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1. 发明申请

US20140064054A1 DETECTION OF DATA IN BURST CUTTING AREA OF OPTICAL DISK 审中-公开
标题翻译：光盘切割区数据检测
公开(公告)号：US20140064054A1
公开(公告)日：2014-03-06
申请号：US14075159
申请日：2013-11-08
申请人： Maarten Kuijper , Bart Van Rompaey , Jacobus Petrus Josephus Heemskerk , Cornelis Marinus Schep , Josephus Arnoldus Henricus Maria Kahlman
发明人： Maarten Kuijper , Bart Van Rompaey , Jacobus Petrus Josephus Heemskerk , Cornelis Marinus Schep , Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G11B7/007
CPC分类号： G11B7/00736 , G11B7/0053 , G11B7/013 , G11B20/00086 , G11B20/10009 , G11B20/1426 , G11B2020/122 , G11B2020/1453 , G11B2220/2541
摘要： An apparatus generates outgoing data to be provided on an optical disk in a burst cutting area. The burst cutting area further comprises markings which cause a marking frequency spectrum when reading out the burst cutting area. The apparatus comprises a channel coder which receives processed data and supplies the outgoing data having an outgoing data frequency spectrum with suppressed DC-content. The apparatus further comprises a data processing device which generates the processed data to obtain an outgoing frequency spectrum wherein a frequency component causing interference with a low frequent component of the markings is suppressed or not present.
摘要翻译：一种装置在突发切割区域中生成要提供在光盘上的输出数据。突发切割区域还包括当读出突发切割区域时引起标记频谱的标记。该装置包括一个信道编码器，它接收处理后的数据，并提供具有抑制的DC内容的输出数据频谱的输出数据。该装置还包括一个数据处理装置，该数据处理装置产生处理后的数据以获得输出频谱，其中抑制或不存在导致对标记的低频成分的干扰的频率分量。

2. 发明申请

US20120250005A1 BIOSENSOR SYSTEM FOR SINGLE PARTICLE DETECTION 有权
标题翻译：用于单颗粒检测的生物传感器系统
公开(公告)号：US20120250005A1
公开(公告)日：2012-10-04
申请号：US13498482
申请日：2010-09-23
申请人： Johannes Joseph Hubertina Barbara Schleipen , Joannes Baptist Adrianus Dionisius Van Zon , Derk Jan Wilfred Klunder , Toon Hendrik Evers , Josephus Arnoldus Henricus Maria Kahlman , Ron Martinus Laurentius Van Lieshout , Mikhail Mikhaylovich Ovsyanko
发明人： Johannes Joseph Hubertina Barbara Schleipen , Joannes Baptist Adrianus Dionisius Van Zon , Derk Jan Wilfred Klunder , Toon Hendrik Evers , Josephus Arnoldus Henricus Maria Kahlman , Ron Martinus Laurentius Van Lieshout , Mikhail Mikhaylovich Ovsyanko
IPC分类号： G01N21/49 , G01R33/12
CPC分类号： G01N33/54373 , G01N15/10 , G01N15/1031 , G01N21/47 , G01N21/49 , G01N21/51 , G01N21/552 , G01N21/6458 , G01N27/72 , G01N33/54313 , G01N2015/0065 , G01N2201/12 , G01R33/1269
摘要： The present invention is related to a biosensor system for the detection of particles comprising: a biosensor cartridge comprising a sensor surface, a biosensor magnet assembly on one side of the cartridge for generating a magnetic field effective at the cartridge and the sensor surface, the first biosensor magnet assembly comprising at least two magnetic sub-units separated by a gap, a first optical detection system for detecting the particles arranged at the same side of the cartridge as the magnet assembly, whereas the magnet assembly is designed in a way that the optical detection is accomplished through the gap of the magnet assembly.
摘要翻译：本发明涉及一种用于检测颗粒的生物传感器系统，包括：生物传感器盒，包括传感器表面，在盒的一侧上的生物传感器磁体组件，用于产生在盒和感测器表面有效的磁场;第一生物传感器磁体组件，其包括由间隙分隔开的至少两个磁性子单元;第一光学检测系统，用于检测与磁体组件位于盒的同一侧的颗粒，而磁体组件设计成使得光学通过磁体组件的间隙实现检测。

3. 发明授权

US08139452B2 Record carrier comprising an additional sync-color pattern and method and device for use with such record carrier 有权
标题翻译：记录载体包括附加的同步颜色图案，以及与这种记录载体一起使用的方法和装置
公开(公告)号：US08139452B2
公开(公告)日：2012-03-20
申请号：US10533505
申请日：2003-11-04
申请人： Josephus Arnoldus Henricus Maria Kahlman
发明人： Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G11B20/22 , G11B7/24
CPC分类号： G11B20/1217 , G11B20/1403 , G11B2020/1287 , G11B2020/1453 , G11B2020/1476
摘要： The invention relates to a format for storing information on an optical recording medium. According to said format the record carrier comprises a synchronization pattern, which synchronization pattern comprises an identifying part consisting of a bit sequence chosen from 100 101, 010 101, 101 001, 010 100 or 100 100.
摘要翻译：本发明涉及一种在光学记录介质上存储信息的格式。根据所述格式，记录载体包括一个同步模式，该同步模式包括一个识别部分，该识别部分由从100 101，010 101，101 001，010 100或100 100中选择的比特序列组成。

4. 发明申请

US20100311183A1 MAGNETIC BEAD ACTUATION USING FEEDBACK FOR FTIR BIOSENSOR 有权
标题翻译：使用FTIR生物传感器反馈的磁珠执行
公开(公告)号：US20100311183A1
公开(公告)日：2010-12-09
申请号：US12865864
申请日：2009-02-02
申请人： Josephus Arnoldus Henricus Maria Kahlman
发明人： Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G01N21/75
CPC分类号： G01N33/54333 , G01N21/552 , G01N27/745 , G01N33/54373 , G01N35/0098
摘要： The invention provides a method for controlling actuation of label particles in a biosensor device, in particular a biosensor device using frustrated total internal reflection. By applying a predetermined actuation force on the label particles and determining the effect of the applied actuation force in a binding volume or surface of a sensor cartridge of the biosensor device, a feedback control of the actuation force is applied. Furthermore, a biosensor device is provided which is adapted for forming the method according to the invention.
摘要翻译：本发明提供一种用于控制生物传感器装置中的标签颗粒致动的方法，特别是使用沮丧的全内反射的生物传感器装置。通过对标签颗粒施加预定的致动力并确定所施加的致动力对生物传感器装置的传感器盒的装订体积或表面的影响，施加致动力的反馈控制。此外，提供适于形成根据本发明的方法的生物传感器装置。

5. 发明申请

US20100290052A1 EVANESCENT FIELD MODULATION IN A BIOSENSOR 有权
标题翻译：生物传感器中的EVANESCENT现场调制
公开(公告)号：US20100290052A1
公开(公告)日：2010-11-18
申请号：US12810867
申请日：2008-12-18
申请人： Johannes Joseph Hubertina Barbara Schleipen , Dominique Maria Bruls , Josephus Arnoldus Henricus Maria Kahlman
发明人： Johannes Joseph Hubertina Barbara Schleipen , Dominique Maria Bruls , Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G01N21/55
CPC分类号： G01N21/552
摘要： The present invention provides an FTIR system comprising a first light source emitting light of a first wavelength, a sample volume with an adjacent sensor surface, a detector for detecting light reflected at said sensor surface. The sensor surface is illuminated by said first light source fulfilling the condition of total internal reflection and generating an evanescent field with a decay length within the sample volume. The system further comprises means for changing the decay length of the evanescent field and means for correlating the detected signals with the change of the decay length of the evanescent field.
摘要翻译：本发明提供了一种FTIR系统，包括发射第一波长的光的第一光源，具有相邻传感器表面的样品体积，用于检测在所述传感器表面反射的光的检测器。所述传感器表面由满足全内反射条件的所述第一光源照射，并产生具有在样品体积内的衰减长度的ev逝场。该系统还包括用于改变ev逝场的衰减长度的装置和用于使检测到的信号与ev逝场的衰减长度变化相关联的装置。

6. 发明申请

US20100188076A1 MICROELECTRONIC SENSOR DEVICE WITH MAGNETIC FIELD GENERATOR AND CARRIER 审中-公开
标题翻译：具有磁场发生器和载体的微电子传感器装置
公开(公告)号：US20100188076A1
公开(公告)日：2010-07-29
申请号：US12667396
申请日：2007-10-23
申请人： Josephus Arnoldus Henricus Maria Kahlman , Jeroen Veen
发明人： Josephus Arnoldus Henricus Maria Kahlman , Jeroen Veen
IPC分类号： G01N27/72
CPC分类号： G01R33/1269 , B01L3/502761 , B01L2200/0636 , B01L2400/043 , G01N21/552 , G01N27/745
摘要： The invention relates to a microelectronic sensor device for manipulating a sample in an exchangeable carrier (111), for example for optically detecting target particles (1) in a sample liquid that is provided in a sample chamber (2) of the carrier (111). The microelectronic sensor device comprises a number of n>1 magnetic field generators (141-143), e.g. electromagnetic coils, with which magnetic fields can be generated in a target region (110). A control unit (150) is provided that can determine and evaluate the mutual coupling or the self-inductance of the magnetic field generators and/or signals from magnetic field sensors attached to the carrier with respect to the presence and/or state of a carrier (111) in the target region (110). In this way, the control unit (150) can for example detect if the carrier (111) is correctly positioned in the sensor device and/or where a magnetically interactive substance (1, 120) is located.
摘要翻译：本发明涉及一种用于操纵可交换载体（111）中的样品的微电子传感器装置，例如用于光学检测设置在载体（111）的样品室（2）中的样品液体中的目标颗粒（1）。微电子传感器装置包括多个n≥1个磁场发生器（141-143），例如，电磁线圈，可以在目标区域（110）中产生磁场。提供控制单元（150），其可以相对于载体的存在和/或状态来确定和评估附接到载体的磁场传感器的磁场发生器和/或信号的相互耦合或自感（111）在目标区域（110）中。以这种方式，控制单元（150）可以例如检测载体（111）是否被正确地定位在传感器装置中和/或磁性交互物质（1,120）所在的位置。

7. 发明申请

US20090278534A1 MAGNETIC SENSOR DEVICE FOR AND A METHOD OF SENSING MAGNETIC PARTICLES 审中-公开
标题翻译：用于感应磁性颗粒的磁传感器装置和方法
公开(公告)号：US20090278534A1
公开(公告)日：2009-11-12
申请号：US12305385
申请日：2007-06-18
申请人： Josephus Arnoldus Henricus Maria Kahlman
发明人： Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G01R33/09
CPC分类号： G01R33/12 , B82Y25/00 , G01N15/0656 , G01N27/745 , G01N33/54326 , G01N33/54373 , G01R33/09 , G01R33/093 , G01R33/1269
摘要： A magnetic sensor device (300) for sensing magnetic particles (15), the magnetic sensor device (300) comprising a magnetic field generator unit (12) adapted for generating a plurality of different magnetic field configurations assigned to a plurality of different magnetic excitation states of the magnetic particles (15), a sensing unit (11) adapted for sensing a plurality of detection signals influenced by the magnetic particles (15) in the different magnetic field configurations, and a combining unit (30) adapted for combining the plurality of signals to thereby derive information indicative of the presence of the magnetic particles (15).
摘要翻译：一种用于感测磁性颗粒（15）的磁性传感器装置（300），该磁性传感器装置（300）包括一个适于产生分配给多个不同磁激励状态的多个不同磁场配置的磁场发生器单元（12）的磁性颗粒（15）的感测单元（11），适用于感测由不同磁场结构中的磁性颗粒（15）影响的多个检测信号的感测单元（11），以及组合单元（30）信号，从而导出指示磁性颗粒（15）的存在的信息。

8. 发明申请

US20090243594A1 METHOD AND DEVICE FOR CHARACTERIZATION OF A MAGNETIC FIELD APPLIED TO A MAGNETIC SENSOR 审中-公开
标题翻译：用于磁性传感器的磁场特性的方法和装置
公开(公告)号：US20090243594A1
公开(公告)日：2009-10-01
申请号：US11721573
申请日：2005-12-20
申请人： Josephus Arnoldus Henricus Maria Kahlman
发明人： Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G01R33/09 , G01R35/00 , G01R33/02
CPC分类号： G01R33/093 , B82Y25/00 , G01N27/745 , G01N35/0098 , G01R33/09 , G01R33/12 , G01R33/1269
摘要： The present invention provides a magnetic sensor device comprising a plurality of magnetic sensor elements having a sensitive direction. At least one of the magnetic sensor elements (43) is provided with a flux-guide (44) for concentrating onto the sensor element in its sensitive direction a magnetic field applied to the magnetic sensor device. The applied magnetic field is thus bent into the sensitive direction of the magnetic sensor element by the flux-guide. In that way, the field strength and/or orientation of the applied magnetic field can be measured in the absence of magnetic particles. This may be used for, for example, calibration of magnetic sensor devices.
摘要翻译：本发明提供一种包括具有敏感方向的多个磁传感器元件的磁传感器装置。磁传感器元件（43）中的至少一个设置有磁通（44），用于在其敏感方向上将传感器元件集中在施加到磁传感器装置的磁场上。所施加的磁场因此通过磁通引导件弯曲成磁传感器元件的敏感方向。以这种方式，可以在没有磁性颗粒的情况下测量施加的磁场的场强和/或取向。这可以用于例如磁传感器装置的校准。

9. 发明申请

US20090206832A1 MAGNETIC SENSOR DEVICE 审中-公开
标题翻译：磁传感器装置
公开(公告)号：US20090206832A1
公开(公告)日：2009-08-20
申请号：US12307790
申请日：2007-07-02
申请人： Josephus Arnoldus Henricus Maria Kahlman , Menno Willem Jose Prins , Jeroen Hans Nieuwenhuis
发明人： Josephus Arnoldus Henricus Maria Kahlman , Menno Willem Jose Prins , Jeroen Hans Nieuwenhuis
IPC分类号： G01N27/72 , G01R33/09
CPC分类号： G01R33/093 , B82Y25/00 , G01N27/745 , G01N33/54333 , G01R33/12 , G01R33/1269
摘要： The present invention provides a magnetic sensor device comprising means (11, 14) for increasing a binding possibility of magnetic or magnetizable objects (15) e.g. magnetic particles, onto the binding sites by applying a moving magnetic field. The present invention furthermore provides a biochip (40) comprising at least one such magnetic sensor and a method for detecting and/or quantifying target moieties in a sample fluid by using such a magnetic sensor.
摘要翻译：本发明提供了一种磁传感器装置，其包括用于增加磁性或可磁化物体（15）的结合可能性的装置（11,14），例如，磁性颗粒，通过施加移动磁场到结合位点。本发明还提供了一种生物芯片（40），其包括至少一个这样的磁传感器以及通过使用这种磁传感器来检测和/或定量样品流体中的目标部分的方法。

10. 发明申请

US20090184706A1 SENSOR DEVICE WITH ADAPTIVE FIELD COMPENSATION 审中-公开
标题翻译：具有自适应场补偿的传感器装置
公开(公告)号：US20090184706A1
公开(公告)日：2009-07-23
申请号：US12302046
申请日：2007-05-11
申请人： Haris Duric , Josephus Arnoldus Henricus Maria Kahlman
发明人： Haris Duric , Josephus Arnoldus Henricus Maria Kahlman
IPC分类号： G01N27/72 , G01R35/00
CPC分类号： G01R33/093 , B82Y25/00 , G01N27/745 , G01N33/54326 , G01R33/12 , G01R33/1269
摘要： The invention relates to a magnetic sensor device comprising an excitation wire for the generation of an alternating magnetic excitation field (Bi) and a GMR sensor (12) for sensing reaction fields (B2) generated by magnetized particles (2) in reaction to the excitation fields. Moreover, it comprises a compensator (15) for the generation of a magnetic compensation field (B3) that adaptively cancels predetermined spectral components of all magnetic fields (B2, B3) which lie in the sensitive direction of the magnetic sensor element (12). Measurements of the GMR sensor (12) are thus made robust against gain variations of the sensor.
摘要翻译：本发明涉及一种磁传感器装置，包括用于产生交变磁场（Bi）的激励线和用于感测由激磁颗粒（2）产生的反应场（B2）的GMR传感器（12）领域。此外，它包括用于产生磁补偿场（B3）的补偿器（15），其自动地消除位于磁传感器元件（12）的敏感方向上的所有磁场（B2，B3）的预定频谱分量。因此，GMR传感器（12）的测量对于传感器的增益变化是鲁棒的。

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