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1. 发明授权

US08529962B2 Method of making demineralized bone particles 有权
标题翻译：脱矿质颗粒的制备方法
公开(公告)号：US08529962B2
公开(公告)日：2013-09-10
申请号：US13010084
申请日：2011-01-20
申请人： John W. Morris , Lawrence A. Shimp , Kenneth C. Petersen , Albert Manrique , David Kaes , Nelson Scarborough , Michael Dowd
发明人： John W. Morris , Lawrence A. Shimp , Kenneth C. Petersen , Albert Manrique , David Kaes , Nelson Scarborough , Michael Dowd
IPC分类号： A61K35/32
CPC分类号： A61K35/32 , A61F2/4644 , A61F2002/4645 , A61K45/06 , A61L27/3608 , A61L27/365 , A61L27/3683 , A61L27/3691 , A61L27/3695 , A61L2430/40 , C07K14/78
摘要： Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles.
摘要翻译：通过使整个骨骼软化，然后再次分解脱矿质骨以提供脱矿质骨颗粒，获得脱矿质骨颗粒。

2. 发明授权

US08268008B2 Osteoimplants and methods for their manufacture 有权
标题翻译：骨架植物及其制造方法
公开(公告)号：US08268008B2
公开(公告)日：2012-09-18
申请号：US11489262
申请日：2006-07-19
申请人： Randal R. Betz , Scott D. Boden , Christine Clark , Nanette Forsyth , John W. Morris , Kathy Traianedes
发明人： Randal R. Betz , Scott D. Boden , Christine Clark , Nanette Forsyth , John W. Morris , Kathy Traianedes
IPC分类号： A61F2/28
CPC分类号： A61F2/28 , A61F2/4455 , A61F2/4644 , A61F2002/2817 , A61F2002/2835 , A61F2002/30059 , A61F2002/30075 , A61F2002/30153 , A61F2002/30329 , A61F2002/30593 , A61F2002/30677 , A61F2002/30805 , A61F2002/30957 , A61F2002/30975 , A61F2002/4649 , A61F2210/0061 , A61F2220/0025 , A61F2230/0019 , A61F2310/00293 , A61F2310/00329 , A61F2310/00365 , A61L27/3608 , A61L27/365 , A61L27/3658 , A61L27/38 , A61L31/005 , A61L2430/02
摘要： An osteoimplant is made up of a coherent aggregate of elongate bone particles.
摘要翻译：骨植入物由细长骨颗粒的相干骨料组成。

3. 发明申请

US20110040334A1 INTERVERTEBRAL IMPLANT WITH MOVEMENT RESISTANT STRUCTURE 有权
标题翻译：具有运动阻力结构的椎间植入物
公开(公告)号：US20110040334A1
公开(公告)日：2011-02-17
申请号：US12914051
申请日：2010-10-28
申请人： David R. Kaes , John W. Morris , Lawrence A. Shimp , John Winterbottom , Fred Geisler
发明人： David R. Kaes , John W. Morris , Lawrence A. Shimp , John Winterbottom , Fred Geisler
IPC分类号： A61B17/88 , A61F2/28 , A61B17/70
CPC分类号： A61F2/28 , A61B17/86 , A61F2/30965 , A61F2/4455 , A61F2/446 , A61F2002/2839 , A61F2002/30057 , A61F2002/30059 , A61F2002/30062 , A61F2002/30131 , A61F2002/30176 , A61F2002/30354 , A61F2002/30405 , A61F2002/30492 , A61F2002/30578 , A61F2002/30677 , A61F2002/30777 , A61F2002/30785 , A61F2002/30836 , A61F2002/30841 , A61F2002/3085 , A61F2002/30904 , A61F2002/4475 , A61F2002/449 , A61F2210/0004 , A61F2220/0025 , A61F2220/0033 , A61F2230/0013 , A61F2230/0054 , A61F2310/00017 , A61F2310/00023 , A61F2310/00131 , A61F2310/00293 , A61F2310/00365
摘要： An implant unit used in surgery has a body made from osteogenic implantable material and including an implant portion and a retaining portion, which is coupled to and extends transversely to the implant portion. The retaining portion is attached to the sidewall of the adjoining vertebral body or mammal bone to prevent displacement of the implant portion relative to the vertebral body or mammal bone and to accelerate fusion therebetween.
摘要翻译：在手术中使用的植入单元具有由成骨可植入材料制成的主体，并且包括植入部分和保持部分，该部分与植入部分相连并横向延伸。保持部分附接到邻接的椎体或哺乳动物骨的侧壁，以防止植入部分相对于椎体或哺乳动物骨骼移位，并加速其间的融合。

4. 发明授权

US07833245B2 Intervertebral implant with movement resistant structure 有权
标题翻译：椎间植入物抗运动结构
公开(公告)号：US07833245B2
公开(公告)日：2010-11-16
申请号：US10483804
申请日：2002-07-12
申请人： David R. Kaes , John W. Morris , Lawrence A. Shimp , John Winterbottom , Fred Geisler
发明人： David R. Kaes , John W. Morris , Lawrence A. Shimp , John Winterbottom , Fred Geisler
IPC分类号： A61B17/70 , A61F2/44
CPC分类号： A61F2/28 , A61B17/86 , A61F2/30965 , A61F2/4455 , A61F2/446 , A61F2002/2839 , A61F2002/30057 , A61F2002/30059 , A61F2002/30062 , A61F2002/30131 , A61F2002/30176 , A61F2002/30354 , A61F2002/30405 , A61F2002/30492 , A61F2002/30578 , A61F2002/30677 , A61F2002/30777 , A61F2002/30785 , A61F2002/30836 , A61F2002/30841 , A61F2002/3085 , A61F2002/30904 , A61F2002/4475 , A61F2002/449 , A61F2210/0004 , A61F2220/0025 , A61F2220/0033 , A61F2230/0013 , A61F2230/0054 , A61F2310/00017 , A61F2310/00023 , A61F2310/00131 , A61F2310/00293 , A61F2310/00365
摘要： An implant unit used in surgery has a body made from osteogenic implantable material and including an implant portion and a retaining portion, which is coupled to and extends transversely to the implant portion. The retaining portion is attached to the sidewall of the adjoining vertebral body or mammal bone to prevent displacement of the implant portion relative to the vertebral body or mammal bone and to accelerate fusion therebetween.
摘要翻译：在手术中使用的植入单元具有由成骨可植入材料制成的主体，并且包括植入部分和保持部分，该部分与植入部分相连并横向延伸。保持部分附接到邻接的椎体或哺乳动物骨的侧壁，以防止植入部分相对于椎体或哺乳动物骨骼移位，并加速其间的融合。

5. 发明授权

US07780708B2 Implant retaining device 失效
标题翻译：植入物保持装置
公开(公告)号：US07780708B2
公开(公告)日：2010-08-24
申请号：US10923392
申请日：2005-01-31
申请人： John W. Morris , Lawrence A. Shimp , David R. Kaes
发明人： John W. Morris , Lawrence A. Shimp , David R. Kaes
IPC分类号： A61B17/70 , A61B17/80
CPC分类号： A61B17/7059 , A61B17/80 , A61B17/86 , A61B2017/00831 , A61F2/28 , A61F2/30749 , A61F2/442 , A61F2/4455 , A61F2/446 , A61F2/447 , A61F2002/2817 , A61F2002/30794 , A61F2220/0008 , A61F2310/00179 , A61F2310/00359
摘要： There is provided an implant retaining device, which has the effect of preventing an intervertebral implant from jutting out of the receiving bed. The implant retaining device generally includes a plate having at least one throughbore to receive a screw, and a screw for securing the plate to the vertebrae. The plate may be dimensioned to cover a portion of the opening of a receiving bed, and thus, need only be secured to a single vertebral body. In an alternate embodiment, the plate may be used during bone fracture correction procedures to prevent a bone screw from backing out of engagement with adjacent bone sections. A method of retaining an intervertebral implant using the device is also provided.
摘要翻译：提供了一种植入物保持装置，其具有防止椎间植入物从接受床突出的作用。植入物保持装置通常包括具有至少一个通孔以容纳螺钉的板和用于将板固定到椎骨的螺钉。该板的尺寸可以确定为覆盖接收床的开口的一部分，因此仅需要固定到单个椎体。在替代实施例中，可以在骨折矫正程序期间使用该板，以防止骨螺钉脱离与相邻骨段的接合。还提供了使用该装置保持椎间植入物的方法。

6. 发明授权

US06368322B1 Surgical bone screw 失效
标题翻译：手术骨螺钉
公开(公告)号：US06368322B1
公开(公告)日：2002-04-09
申请号：US09542556
申请日：2000-04-03
申请人： Howard J. Luks , John W. Boyle , Lawrence A. Shimp , David R. Kaes , John W. Morris , Erik O. Martz , Daniel E. Rosenthal
发明人： Howard J. Luks , John W. Boyle , Lawrence A. Shimp , David R. Kaes , John W. Morris , Erik O. Martz , Daniel E. Rosenthal
IPC分类号： A61B1786
CPC分类号： A61B17/864 , A61B17/861 , A61B17/8645 , A61B17/866 , A61B17/8877 , Y10S606/91
摘要： An interference screw suitable for surgical use is provided. The interference screw is constructed from bone and includes an elongated body having an outer threaded surface, a tapered insertion end and a central throughbore. Insertion tool engaging structure is formed along the walls defining the throughbore. The insertion tool engaging structure extends from the proximal end of the elongated body over a substantial portion of the length of the elongated body. The insertion tool engaging structure functions to distribute the forces required to insert the interference screw throughout the body of the interference screw to prevent fracturing of the interference screw during insertion into bone.
摘要翻译：提供适合于外科手术的干涉螺钉。干涉螺钉由骨构成并且包括具有外螺纹表面，锥形插入端和中心穿透孔的细长主体。插入工具接合结构沿着限定穿透孔的壁形成。插入工具接合结构在细长体的长度的大部分上从细长体的近端延伸。插入工具接合结构用于分配将干涉螺钉插入干涉螺钉的整个主体所需的力，以防止在插入骨中时干扰螺钉的断裂。

7. 发明授权

US06277149B1 Ramp-shaped intervertebral implant 有权
标题翻译：斜坡状椎间植入物
公开(公告)号：US06277149B1
公开(公告)日：2001-08-21
申请号：US09328242
申请日：1999-06-08
申请人： John W. Boyle , Lawrence A. Shimp , David R. Kaes , John W. Morris , Erik O. Martz , Todd M. Boyce , Mark Daugherty
发明人： John W. Boyle , Lawrence A. Shimp , David R. Kaes , John W. Morris , Erik O. Martz , Todd M. Boyce , Mark Daugherty
IPC分类号： A61F244
CPC分类号： A61F2/4611 , A61F2/28 , A61F2/30771 , A61F2/30965 , A61F2/442 , A61F2/4465 , A61F2/447 , A61F2002/2817 , A61F2002/2825 , A61F2002/2835 , A61F2002/30112 , A61F2002/30115 , A61F2002/30131 , A61F2002/30153 , A61F2002/30158 , A61F2002/3023 , A61F2002/30235 , A61F2002/30238 , A61F2002/30266 , A61F2002/3028 , A61F2002/30324 , A61F2002/30772 , A61F2002/30774 , A61F2002/30785 , A61F2002/30789 , A61F2002/3082 , A61F2002/30836 , A61F2002/30843 , A61F2002/30904 , A61F2002/30952 , A61F2002/4623 , A61F2002/4627 , A61F2002/4649 , A61F2230/0004 , A61F2230/0006 , A61F2230/0013 , A61F2230/0019 , A61F2230/0026 , A61F2230/0063 , A61F2230/0069 , A61F2230/0082 , A61F2250/0036 , A61F2310/00017 , A61F2310/00023 , A61F2310/00131 , A61F2310/00293 , A61F2310/00359
摘要： A ramp-shaped intervertebral implant is disclosed. The implant has a body having a first end, a second end, a top surface and a bottom surface. At least one of the top and bottom surfaces is tapered and converges towards the second end of the body. An opening extends through the body and has one end opening onto the top surface of the implant and the other end opening onto the bottom surface of the implant. The implant can be formed from the diaphysis or metaphysis of a long bone, wherein the intramedullary canal of the long bone defines the opening. Alternately, the implant can be made from any biocompatible material having the requisite strength requirement.
摘要翻译：公开了一种斜坡状椎间植入物。植入物具有具有第一端，第二端，顶表面和底表面的主体。顶表面和底表面中的至少一个是锥形的并且朝向身体的第二端会聚。开口延伸穿过主体并且在植入物的顶表面上具有一个端部开口，并且另一端开口延伸到植入物的底表面上。植入物可以由长骨的骨干或干be形成，其中长骨的髓内管限定开口。或者，植入物可以由具有必要强度要求的任何生物相容性材料制成。

8. 发明授权

US5928238A Bone dowel cutter 失效
标题翻译：骨榫刀
公开(公告)号：US5928238A
公开(公告)日：1999-07-27
申请号：US773191
申请日：1996-12-27
申请人： Nelson Scarborough , John W. Morris
发明人： Nelson Scarborough , John W. Morris
IPC分类号： A61B10/00 , A61B10/02 , A61B17/00 , A61B17/16 , A61B17/32 , A61F2/28 , A61F2/30 , A61F2/46
CPC分类号： A61F2/4644 , A61B17/1637 , A61B10/025 , A61B17/32053 , A61B2017/00969 , A61F2/3094 , A61F2002/2839 , A61F2002/4649 , Y10T408/8923 , Y10T408/8973 , Y10T408/90
摘要： A device is provided for cutting dowels from a bone mass which is easily disassembled for cleaning and sterilization. The dowel cutter includes an axial mounting member having a proximal end portion configured for engagement with a drill chuck and a distal end portion configured to receive a cylindrical cutting blade, an elongated supporting shaft having a distal end portion configured to support a drill guide, and a securement mechanism formed integral with the mounting member for releasably maintaining the relative orientation of the supporting shaft and the axial mounting member during utilization.
摘要翻译：提供一种用于从骨块切割榫钉的装置，其易于拆卸以进行清洁和灭菌。定位销切割器包括轴向安装构件，该轴向安装构件具有构造成用于与钻头卡盘接合的近端部分和构造成接收圆柱形切割刀片的远端部分，细长支撑轴，其具有构造成支撑钻子引导器的远端部分，以及与安装构件形成一体的固定机构，用于在使用期间可释放地保持支撑轴和轴向安装构件的相对定向。

9. 发明授权

US5846484A Pressure flow system and method for treating a fluid permeable workpiece such as a bone 失效
标题翻译：压力流动系统和用于处理流体可渗透的工件（例如骨）的方法
公开(公告)号：US5846484A
公开(公告)日：1998-12-08
申请号：US821603
申请日：1997-03-20
申请人： Nelson L. Scarborough , John W. Morris , James L. Russell , Michael Dowd
发明人： Nelson L. Scarborough , John W. Morris , James L. Russell , Michael Dowd
IPC分类号： B08B5/02 , A61L2/00 , A61L27/00 , A61L27/36 , B08B3/02 , A61M31/00
CPC分类号： A61F2/4644 , A61L2/0088 , A61L27/3608 , A61L27/3683 , A61F2002/4646 , Y10S623/923
摘要： A pressure flow system and method for its use are provided for contacting the interior of a fluid permeable, e.g., porous, workpiece. The system includes a fluid pressure chamber having an inlet port and an opening formed in one of the chamber walls. An adjustable seal capable of providing a fluid-tight seal about the exterior of a workpiece having a non-uniform surface is positioned within the opening. Fluid under pressure is supplied to the pressure chamber to force fluid to flow through the internal matrix of the workpiece. In a preferred embodiment, the workpiece is a bone or a section thereof, and the fluid is forced to flow from the endosteal portion of bone to the periosteal portion of bone through the vasculature and porous structure of the bone to remove blood, bone marrow and/or other non-bone constituent(s) from the bone. Alternatively, the fluid can be chosen to decontaminate and/or demineralize the bone, to stain the bone to improve visualization of the bone microvasculature or to impregnate with pharmacological agents (antibiotics, bone growth factors, etc.) so that bone can act as a delivery system.
摘要翻译：提供了一种压力流动系统及其使用方法，用于使流体可渗透的例如多孔的工件的内部接触。该系统包括流体压力室，其具有形成在其中一个室壁中的入口和开口。能够在具有不均匀表面的工件的外部提供流体密封的可调节密封件定位在开口内。在压力下的流体被供应到压力室以迫使流体流过工件的内部基体。在优选实施例中，工件是骨或其部分，并且迫使流体通过骨的脉管系统和多孔结构从骨的内膜部分流动到骨的骨膜部分，以去除血液，骨髓和 /或来自骨的其它非骨组分。或者，可以选择流体以对骨进行去污和/或去矿物质，染色骨以改善骨微血管的可视化或用药物（抗生素，骨生长因子等）浸渍，使得骨可以作为输送系统。

10. 发明授权

US5654977A Method and apparatus for real time defect inspection of metal at elevated temperature 失效
标题翻译：金属在高温下进行实时缺陷检测的方法和装置
公开(公告)号：US5654977A
公开(公告)日：1997-08-05
申请号：US382526
申请日：1995-02-02
申请人： John W. Morris
发明人： John W. Morris
IPC分类号： G01N25/72 , G01N33/20
CPC分类号： G01N33/20 , G01N25/72
摘要： A system for detecting, in real time, the existence, depth, extent, and type of a defect in an above ambient temperature object which has been formed by working or other heat input. Such defect detection is performed by analyzing IR emissions from the product, and from a defect site in particular, in order to assess the characteristics of the detected defect. The defect observables are then compared with known defect training data in order to characterize the defect as to type, depth and extent.
摘要翻译：一种用于实时检测由工作或其它热输入形成的上述环境温度对象中的缺陷的存在，深度，程度和类型的系统。通过分析来自产品的IR发射，特别是从缺陷部位来进行这种缺陷检测，以评估检测到的缺陷的特性。然后将缺陷可观察值与已知的缺陷训练数据进行比较，以表征关于类型，深度和程度的缺陷。

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