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    • 5. 发明授权
    • Microfabricated gas chromatograph
    • 微型气相色谱仪
    • US08132443B2
    • 2012-03-13
    • US12434180
    • 2009-05-01
    • R Andrew McGillRekha PaiDavid R. MottJennifer L StepnowskiViet Nguyen
    • R Andrew McGillRekha PaiDavid R. MottJennifer L StepnowskiViet Nguyen
    • B01D53/02
    • G01N30/6095B01J20/205B01J20/282B01J20/285B01J2220/54B01L3/502707B01L3/502746B01L2200/0689B01L2300/0816B01L2300/0883B01L2300/1827G01N2030/025
    • The present invention is generally directed to a microfabricated gas chromatograph column having two patterned substrates, each optionally having a stationary phase material coating, bonded together to provide a continuous flow channel. The flow channel can have a serpentine arrangement or a modified serpentine arrangement comprising alternating series of consecutive turns in one direction where each series has enough turns to move carrier gas and analyte molecules from the center of the column cross section to an outer wall of the channel or from one outer wall of the channel to the opposite outer wall. Different portions of the substrates can be coated with differing thicknesses of stationary phase material and/or with different stationary phase materials. The column can have a circular cross-section or a semi-circular cross-section where the flat portion of the cross-section has grooves. Also disclosed is the related method of making the microfabricated gas chromatograph column.
    • 本发明一般涉及一种具有两个图案化基底的微制造气相色谱柱,每个图案化基底可任选地具有固定相材料涂层,粘合在一起以提供连续的流动通道。 流动通道可以具有蛇形排列或修改的蛇形结构,其包括在一个方向上交替连续的连续匝数,其中每个系列具有足够的匝数以将载气和分析物分子从柱截面的中心移动到通道的外壁 或从通道的一个外壁到相对的外壁。 可以用不同厚度的固定相材料和/或用不同的固定相材料涂覆不同部分的基材。 该柱可以具有圆形横截面或半圆形横截面,其中横截面的平坦部分具有凹槽。 还公开了制造微细气相色谱仪柱的相关方法。