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1. 发明申请

US20110172643A1 Catheter with Composite Stiffener 有权
标题翻译：导管与复合加强筋
公开(公告)号：US20110172643A1
公开(公告)日：2011-07-14
申请号：US13045102
申请日：2011-03-10
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译：导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。第一和第二加强件同轴地缠绕在近端内衬的外部。远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。第一加强件在到达远端部分之前终止。

2. 发明授权

US07104979B2 Catheter with composite stiffener 有权
公开(公告)号：US07104979B2
公开(公告)日：2006-09-12
申请号：US10079103
申请日：2002-02-19
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.

3. 发明授权

US5995208A Intravascular oximetry catheter 失效
标题翻译：血管内血氧饱和度测定导管
公开(公告)号：US5995208A
公开(公告)日：1999-11-30
申请号：US86789
申请日：1998-05-28
申请人： Jeffrey A. Sarge , Scott T. Tsuchitani , Harlow B. Christianson , Gerald G. Vurek , John M. Sperinde , Darrell H. Ogi
发明人： Jeffrey A. Sarge , Scott T. Tsuchitani , Harlow B. Christianson , Gerald G. Vurek , John M. Sperinde , Darrell H. Ogi
IPC分类号： A61B5/00 , G01N33/48
CPC分类号： A61B5/1459
摘要： Apparatus and a method for monitoring a percentage of the oxygen saturation in the hemoglobin of blood flowing through a blood vessel. An optical sensor that detects the percentage oxygen saturation in blood is disposed proximate a proximal end of the catheter. A thermistor is disposed adjacent to the distal end of the catheter and it is employed to detect changes in blood temperature that indicate the position of the catheter's distal end in the blood vessel. Indicia or marks visible at intervals on the outer surface of the catheter enable a medical practitioner to determine the length of the catheter that has been introduced into the blood vessel. A strain relief that is flexible and resists stretching extends along the length of the catheter. For flushing the distal end of the catheter, a fluid supply may be connected to a lumen running through the catheter to provide the flushing fluid. A removable guide wire is inserted in the lumen when positioning the distal end of the catheter at a location in the blood vessel and provides enhanced rigidity for this purpose. The catheter may be coated with an anticoagulant such as heparin, to prevent blood from coagulating on the exterior surface of the catheter.
摘要翻译：用于监测流过血管的血液的血红蛋白中的氧饱和度百分比的装置和方法。检测血液中氧饱和度百分比的光学传感器设置在导管近端附近。热敏电阻设置在导管的远端附近，并且用于检测指示导管远端在血管中的位置的血液温度变化。在导管的外表面上以间隔可见的标记或标记使医生能够确定已经被导入血管的导管的长度。柔韧且抗拉伸的应变消除部沿着导管的长度延伸。为了冲洗导管的远端，流体供应可以连接到穿过导管的内腔，以提供冲洗液。当将导管的远端定位在血管中的位置时，将可移除的导丝线插入内腔，并为此提供增强的刚性。导管可以用抗凝血剂如肝素涂覆，以防止血液凝结在导管的外表面上。

4. 发明授权

US5891114A Soft-tip high performance braided catheter 失效
标题翻译：软尖高性能编织导管
公开(公告)号：US5891114A
公开(公告)日：1999-04-06
申请号：US941511
申请日：1997-09-30
申请人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
发明人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M2025/0081 , A61M25/0054
摘要： This is a catheter assembly which may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of a stainless steel or super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter section having a thin wall, controlled stiffness, and high resistance to kinking. The distal-most section of the catheter is much more flexible than are other braided catheters of the genre due to choice of braid construction features of that distal-most section. The distal-most braid, and optionally, intermediate braid components are constructed to be more flexible than the more proximal sections due to deletion of ribbons from the braid structure, change of ribbon material, and change of pitch. The various sections include braids which may have a consistent pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections also due to the presence of stiff polymeric tubing or composited materials in the stiffer section.
摘要翻译：这是一种导管组件，其可以用于进入身体内的组织靶，通常是可通过血管系统接近的靶。本发明的中心是使用通常为不锈钢或超弹性合金带的编织金属加强件，其位于导管主体内，以便产生具有薄壁，受控刚度和高度的导管部分耐扭结。由于选择最远部分的编织结构特征，导管的最远端部分比其他类型的编织导管更加灵活。最远的编织物和任选的中间编织部件被构造成比近侧部分更柔软，这是由于从编织结构中删除丝带，带状材料的变化和间距的变化。各个部分包括可以具有一致间距的编织物或者可以沿着导管或导管部分的轴线的间距变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。导管组件的近端部分通常比较远的部分基本上更硬，这也是由于在刚性部分中存在刚性聚合物管或复合材料。

5. 发明授权

US5611338A Multi-purpose multi-parameter cardiac catheter 失效
标题翻译：多功能多参数心脏导管
公开(公告)号：US5611338A
公开(公告)日：1997-03-18
申请号：US315033
申请日：1994-09-29
申请人： David A. Gallup , John M. Sperinde , William A. Ambrisco , Timothy J. Hughes , Anthony J. Pantages , Jeffrey A. Sarge , Scott T. Tsuchitani
发明人： David A. Gallup , John M. Sperinde , William A. Ambrisco , Timothy J. Hughes , Anthony J. Pantages , Jeffrey A. Sarge , Scott T. Tsuchitani
IPC分类号： A61B5/00 , A61B5/028 , A61B5/145 , A61B5/1459
CPC分类号： A61B5/028 , A61B5/1459
摘要： A multi-lumen, multi-purpose cardiac catheter which incorporates optical filaments and an optical coupler for use with external apparatus for determining the oxygen concentration in the blood of a patient under critical care conditions, as well as incorporating therein a thermal element useable with a second external apparatus for measurement of continuous cardiac output. The thermal element is disposed at a necked down portion of the catheter at the distal end thereof, with at least one of the lumens of the catheter substantially compressed at the necked down portion thereof. The catheter also includes a thermistor and at least one injectate port for enabling the user to also conduct thermal dilution readings and obtain intermittent measurements of cardiac output. The combination of a thermal dilution catheter with a SVO.sub.2 catheter and a continuous cardiac output catheter gives the multi-purpose catheter above described substantial versatility as well as providing the user with a versatile cardiac catheter device which enables him to conduct multiple evaluations of disparate blood-related parameters which require the use of separate apparatus. Simply by switching from one external apparatus to the other, the user can obtain readings for different blood-related parameters useful in the treatment of the cardiac patient.
摘要翻译：一种多腔多用途心脏导管，其包含光纤丝和用于外部设备的光耦合器，用于确定在危重护理条件下患者血液中的氧浓度，以及在其中结合使用的热元件用于测量连续心输出量的第二外部装置。热元件设置在导管的远端处的颈缩部分，其中导管的至少一个腔在其颈缩部分基本上被压缩。导管还包括热敏电阻和至少一个注射口，用于使用户能够进行热稀释读数并获得心输出量的间歇测量。热稀释导管与SVO2导管和连续心输出导管的组合给出了多用途导管以上描述的实质性多功能性，并为使用者提供了多功能心脏导管装置，使他能够进行不同血液 - 需要使用分离设备的相关参数。简单地通过从一个外部设备切换到另一个外部设备，用户可以获得用于治疗心脏病人的不同血液相关参数的读数。

6. 发明授权

US06508804B2 Catheter having continuous lattice and coil reinforcement 有权
标题翻译：导管具有连续的格子和线圈加固
公开(公告)号：US06508804B2
公开(公告)日：2003-01-21
申请号：US09363122
申请日：1999-07-28
申请人： Jeffrey A. Sarge , Henry Nita , Simon Ngoc Huu Nguyen
发明人： Jeffrey A. Sarge , Henry Nita , Simon Ngoc Huu Nguyen
IPC分类号： A61M2500
CPC分类号： A61M25/0053 , A61M25/005
摘要： A reinforced intravascular catheter adapted for use in performing minimally invasive medical procedures. A catheter, in accordance with the present invention, comprising an inner tubular member having an outer surface, a proximal end, a distal end, and a lumen extending therethrough. The catheter further including a support member overlaying the inner tubular member and conforming to the outer surface thereof, the support member including at least one filament forming a plurality of turns. The support member further including at least one multi-layered portion having a first layer and a plurality of additional layers, each layer comprising a plurality of turns formed by at least one filament, the plurality of additional layers each overlaying at least the first layer. The catheter also including an outer layer overlaying both the support member and the inner tubular member. A method of fabricating a catheter in accordance with the present invention is also disclosed.
摘要翻译：适用于执行微创医疗程序的强化血管内导管。根据本发明的导管包括具有外表面，近端，远端和延伸通过其的内腔的内管状构件。所述导管还包括覆盖所述内管状构件并与其一致的外表面的支撑构件，所述支撑构件包括形成多个匝的至少一个细丝。支撑构件还包括具有第一层和多个附加层的至少一个多层部分，每个层包括由至少一个细丝形成的多个匝，所述多个附加层各自至少覆盖第一层。导管还包括覆盖支撑构件和内部管状构件的外层。还公开了根据本发明的制造导管的方法。

7. 发明授权

US06368316B1 Catheter with composite stiffener 失效
公开(公告)号：US06368316B1
公开(公告)日：2002-04-09
申请号：US09096267
申请日：1998-06-11
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M2500
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.

8. 发明授权

US06575959B1 Catheter incorporating an insert molded hub and method of manufacturing 有权
标题翻译：导管插入嵌入式毂和制造方法
公开(公告)号：US06575959B1
公开(公告)日：2003-06-10
申请号：US09472265
申请日：1999-12-27
申请人： Jeffrey A. Sarge , Lex P. Jansen , Lawrence C. Alpert , Greg P Welsh
发明人： Jeffrey A. Sarge , Lex P. Jansen , Lawrence C. Alpert , Greg P Welsh
IPC分类号： A61M2516
CPC分类号： A61M25/0014 , A61M25/0009 , B29L2031/7542 , Y10S128/06 , Y10S128/26
摘要： A catheter for use in vasculature or other lumens within body structures includes a shaft formed from an elongated polymeric flexible tube. A thin polymeric sleeve is placed over a proximal portion of the catheter shaft. A hub structure is injection molded over the sleeve with a polymer of the same type as the polymeric sleeve. The heat from the injection molded polymer of the hub body is sufficient to heat the polymeric sleeve, causing the polymeric sleeve to bond the hub body to the sleeve, and the sleeve to the catheter shaft. In this way, the injection molded polymeric hub structure is fused to the catheter shaft, with a unified polymeric bond, and without the use of adhesive. The plastic sleeve is sufficiently thick to protect the catheter shaft from the heat of the injection molded molten polymer while still allowing the catheter shaft and sleeve to bond to the shaft.
摘要翻译：用于体内结构中的脉管系统或其他内腔的导管包括由细长的聚合物柔性管形成的轴。将薄的聚合物套管置于导管轴的近端部分上。轮毂结构在套筒上用与聚合物套筒相同类型的聚合物注塑成型。来自轮毂体的注射聚合物的热量足以加热聚合物套筒，导致聚合物套筒将轮毂体与套筒结合，并将套筒粘合到导管轴上。以这种方式，注塑聚合物毂结构与导管轴熔合，具有统一的聚合物粘合，并且不使用粘合剂。塑料套筒足够厚以保护导管轴免受注塑熔融聚合物的热量的影响，同时仍然允许导管轴和套筒结合到轴上。

9. 发明授权

US06165163A Soft-tip performance braided catheter 有权
标题翻译：软尖性能编织导管
公开(公告)号：US06165163A
公开(公告)日：2000-12-26
申请号：US277010
申请日：1999-03-26
申请人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
发明人： Thomas Yung-Hui Chien , Lex P. Jansen , Henry Nita , Jeffrey A. Sarge
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/0054 , A61M2025/0081
摘要： This is a catheter assembly which may be used in accessing a tissue target within the body, typically a target which is accessible through the vascular system. Central to the invention is the use of a braided metallic reinforcing member, typically of a stainless steel or super-elastic alloy ribbon, situated within the catheter body in such a way to create a catheter section having a thin wall, controlled stiffness, and high resistance to kinking. The distal-most section of the catheter is much more flexible than are other braided catheters of the genre due to choice of braid construction features of that distal-most section. The distal-most braid, and optionally, intermediate braid components are constructed to be more flexible than the more proximal sections due to deletion of ribbons from the braid structure, change of ribbon material, and change of pitch. The various sections include braids which may have a consistent pitch or may vary in pitch along the axis of the catheter or catheter section. The braided ribbon reinforcing member typically is placed between a flexible outer tubing member and an inner tubing member to produce a catheter section which is very flexible but highly kink resistant. The more proximal sections of the catheter assembly are often substantially stiffer than the more distal sections also due to the presence of stiff polymeric tubing or composited materials in the stiffer section.
摘要翻译：这是一种导管组件，其可以用于进入身体内的组织靶，通常是可通过血管系统接近的靶。本发明的中心是使用通常为不锈钢或超弹性合金带的编织金属加强件，其位于导管主体内，以便产生具有薄壁，受控刚度和高度的导管部分耐扭结。由于选择最远部分的编织结构特征，导管的最远端部分比其他类型的编织导管更加灵活。最远的编织物和任选的中间编织部件被构造成比近侧部分更柔软，这是由于从编织结构中删除丝带，带状材料的变化和间距的变化。各个部分包括可以具有一致间距的编织物或者可以沿着导管或导管部分的轴线的间距变化。编织带加强构件通常放置在柔性外管构件和内管构件之间以产生非常柔性但高度扭结的导管部分。导管组件的近端部分通常比较远的部分基本上更硬，这也是由于在刚性部分中存在刚性聚合物管或复合材料。

10. 发明授权

US08317772B2 Catheter with composite stiffener 有权
标题翻译：导管与复合加强筋
公开(公告)号：US08317772B2
公开(公告)日：2012-11-27
申请号：US13045102
申请日：2011-03-10
申请人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
发明人： Lex P. Jansen , Thomas Yung-Hui Chien , Perry Alvin Fukui , Jeffrey A. Sarge , Lawrence Charles Alpert
IPC分类号： A61M25/00
CPC分类号： A61M25/0053 , A61M25/005 , A61M25/0054
摘要： A catheter comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member comprises a relatively stiff proximal section and a relatively flexible distal section. The proximal section includes an inner tubular liner, a first stiffener comprising a metal alloy, and a second stiffener comprising a non-metal alloy. The first and second stiffeners are coaxially wound exterior to the proximal inner liner. The distal section includes a distal inner tubular liner and the second stiffener coaxially wound exterior to the distal inner liner. The first stiffener terminates before reaching the distal section.
摘要翻译：导管，其包括具有近端，远端和限定在所述近端和远端之间延伸的内腔的通道的细长管状构件。细长管状构件包括相对刚性的近端部分和相对柔性的远端部分。近端部分包括内部管状衬垫，包括金属合金的第一加强件和包括非金属合金的第二加强件。第一和第二加强件同轴地缠绕在近端内衬的外部。远侧部分包括远侧内部管状衬垫，并且第二加强件同轴地缠绕在远端内衬套的外部。第一加强件在到达远端部分之前终止。

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