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1. 发明授权

US06975893B2 Mass transport limited in vivo analyte sensor 有权
标题翻译：大量运输有限的体内分析物传感器
公开(公告)号：US06975893B2
公开(公告)日：2005-12-13
申请号：US10723381
申请日：2003-11-25
申请人： James L. Say , Henning Sakslund , Michael F. Tomasco , Jay D. Audett , Hyun Cho , Duane O. Yamasaki , Adam Heller
发明人： James L. Say , Henning Sakslund , Michael F. Tomasco , Jay D. Audett , Hyun Cho , Duane O. Yamasaki , Adam Heller
IPC分类号： G01N33/483 , A61B5/00 , A61B5/145 , A61B5/1468 , A61B5/1486 , C12Q1/00 , G01N27/327 , G01N27/416 , G01N27/49 , G01N33/487 , A61B5/05
CPC分类号： A61B5/14865 , A61B5/1486 , C12Q1/002 , C12Q1/006 , Y10S977/925
摘要： An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.
摘要翻译：包括工作电极和靠近工作电极的分析物响应感测层的体内电化学传感器。感测层暴露在传感器的边缘处，其中传感器信号至少部分地通过质量传送分析物到感测层而受到限制。传感器被配置和布置成用于植入哺乳动物的身体以与哺乳动物体液接触。分析物经由传感器的边缘扩散到感测元件，从而限制分析物到传感元件的质量传递。这是因为传感器边缘的溶液接触表面积远小于感测层的开放面。

2. 发明授权

US5066728A Radiation-reactive phenylbutadiene multiblock copolymers 失效
标题翻译：辐射反应性苯基丁二烯多嵌段共聚物
公开(公告)号：US5066728A
公开(公告)日：1991-11-19
申请号：US589139
申请日：1990-09-27
申请人： Jay D. Audett
发明人： Jay D. Audett
IPC分类号： C08F297/02 , C09J153/00
CPC分类号： C08F297/02 , C09J153/00
摘要： A multiblock copolymer comprising endblocks of phenylbutadiene and an elastomeric midblock of a conjugated diene such as isoprene or butadiene is disclosed. The copolymer is crosslinkable by EB radiation such that the crosslinks are confined primarily to the endblock domains in the polymer with minimal crosslinking occurring in the rubbery matrix. Also disclosed are blends of the copolymers with tackifier resins compatible with the midblock regions. The blends provide a curable PSA having enhanced cohesive strength while maintaining adhesive properties.
摘要翻译：公开了包含苯基丁二烯的端基和共轭二烯的弹性体中间嵌段如异戊二烯或丁二烯的多嵌段共聚物。该共聚物可通过EB辐射进行交联，使得交联键主要限于聚合物中的末端嵌段结构域，而在橡胶基体中发生最少的交联。还公开了共聚物与与中间区域相容的增粘树脂的共混物。共混物提供具有增强的内聚强度同时保持粘合性能的可固化PSA。

3. 发明授权

US5587261A UV/EB curable butyl copolymers for lithographic and corrosion-resistant coating 失效
标题翻译：用于平版印刷和耐腐蚀涂层的UV / EB可固化丁基共聚物
公开(公告)号：US5587261A
公开(公告)日：1996-12-24
申请号：US473858
申请日：1995-06-07
申请人： Jay D. Audett , Kenneth O. McElrath
发明人： Jay D. Audett , Kenneth O. McElrath
IPC分类号： C09D123/22 , C08F2/46 , C08F8/00 , C08L23/22 , C09D123/02 , C09D125/00 , C09D125/18 , G03F7/028 , G03F7/038 , G03C3/00 , B41N1/00 , B41N6/00 , G03F7/00
CPC分类号： G03F7/0388 , C08F8/00 , C08L23/22 , Y02P20/582 , Y10S430/106 , Y10S430/114 , Y10S430/116 , Y10S430/117 , Y10S522/904 , Y10S522/905
摘要： A lithographic coating and method of framing a lithographic image are disclosed. The method comprises coating at least a portion of a surface of an article with a radiation-crosslinkable polymer, and exposing the coated surface to a pattern of radiation to crosslink the polymer in a lithographic image. The functionalized polymer is a copolymer of an isoolefin of 4 to 7 carbon atoms and para-alkylstyrene, wherein the para-alkylstyrene is functionalized with a radiation reactive group at the para-alkyl group of the para-alkylstyrene.
摘要翻译：公开了一种平版印刷涂层和一种构图平版印刷图像的方法。该方法包括用辐射可交联的聚合物涂覆制品的表面的至少一部分，并将涂覆的表面暴露于辐射图案以在光刻图像中交联聚合物。官能化聚合物是具有4至7个碳原子的异烯烃和对 - 烷基苯乙烯的共聚物，其中对烷基苯乙烯用对位烷基苯乙烯的对位烷基上的辐射反应性基团官能化。

4. 发明授权

US5376503A UV/EB curable copolymers for lithographic and corrosion-resistant coating applications 失效
标题翻译：用于平版印刷和耐腐蚀涂层应用的UV / EB可固化共聚物
公开(公告)号：US5376503A
公开(公告)日：1994-12-27
申请号：US982104
申请日：1992-11-24
申请人： Jay D. Audett , Kenneth O. McElrath
发明人： Jay D. Audett , Kenneth O. McElrath
IPC分类号： C09D123/22 , C08F2/46 , C08F8/00 , C08L23/22 , C09D123/02 , C09D125/00 , C09D125/18 , G03F7/028 , G03F7/038 , G03C1/492
CPC分类号： G03F7/0388 , C08F8/00 , C08L23/22 , Y02P20/582 , Y10S430/106 , Y10S430/114 , Y10S430/116 , Y10S430/117 , Y10S522/904 , Y10S522/905
摘要： A lithographic coating and method of framing a lithographic image are disclosed. The method comprises coating at least a portion of a surface of an article with a radiation-crosslinkable polymer, and exposing the coated surface to a pattern of radiation to crosslink the polymer in a lithographic image. The functionalized polymer is a copolymer of an isoolefin of 4 to 7 carbon atoms and para-alkylstyrene, wherein the para-alkylstyrene is functionalized with a radiation reactive group at the para-alkyl group of the para-alkylstyrene.
摘要翻译：公开了一种平版印刷涂层和一种构图平版印刷图像的方法。该方法包括用辐射可交联的聚合物涂覆制品的表面的至少一部分，并将涂覆的表面暴露于辐射图案以在光刻图像中交联聚合物。官能化聚合物是具有4至7个碳原子的异烯烃和对 - 烷基苯乙烯的共聚物，其中对烷基苯乙烯用对位烷基苯乙烯的对位烷基上的辐射反应性基团官能化。

5. 发明授权

US5135816A Radiation-reactive phenylbutadiene multiblock copolymers 失效
标题翻译：辐射反应性苯基丁二烯多嵌段共聚物
公开(公告)号：US5135816A
公开(公告)日：1992-08-04
申请号：US763093
申请日：1991-09-20
申请人： Jay D. Audett
发明人： Jay D. Audett
IPC分类号： C08F297/02 , C09J153/00
CPC分类号： C08F297/02 , C09J153/00 , Y10T428/31645 , Y10T428/31696 , Y10T428/31833 , Y10T428/31899 , Y10T428/31924 , Y10T428/31931
摘要： A method for preparing a substrate coated or laminated with a multiblock copolymer comprising endblocks of phenylbutadiene and an elastomeric midblock of a conjugated diene such as isoprene or butadiene is disclosed. The copolymer is crosslinkable by EB radiation such that the crosslinks are confined primarily to the endblock domains in the polymer with minimal crosslinking occurring in the rubbery matrix. Also disclosed are blends of the copolymers with tackifier resins compatible with the midblock regions. The blends provide a curable PSA having enhanced cohesive strength while maintaining adhesive properties.
摘要翻译：公开了一种制备涂覆或层压有多嵌段共聚物的基材的方法，该多嵌段共聚物包含苯基丁二烯的端嵌段和共轭二烯如异戊二烯或丁二烯的弹性体中间嵌段。该共聚物可通过EB辐射进行交联，使得交联键主要限于聚合物中的末端嵌段结构域，而在橡胶基体中发生最少的交联。还公开了共聚物与与中间区域相容的增粘树脂的共混物。共混物提供具有增强的内聚强度同时保持粘合性能的可固化PSA。

6. 发明授权

US5585416A UV/EB curable butyl copolymers for lithographic and corrosion-resistant coating applications 失效
公开(公告)号：US5585416A
公开(公告)日：1996-12-17
申请号：US478303
申请日：1995-06-07
申请人： Jay D. Audett , Kenneth O. McElrath
发明人： Jay D. Audett , Kenneth O. McElrath
IPC分类号： C09D123/22 , C08F2/46 , C08F8/00 , C08L23/22 , C09D123/02 , C09D125/00 , C09D125/18 , G03F7/028 , G03F7/038 , C08J3/28 , G03C3/00
CPC分类号： G03F7/0388 , C08F8/00 , C08L23/22 , Y02P20/582 , Y10S430/106 , Y10S430/114 , Y10S430/116 , Y10S430/117 , Y10S522/904 , Y10S522/905
摘要： A lithographic coating and method of framing a lithographic image are disclosed. The method comprises coating at least a portion of a surface of an article with a radiation-crosslinkable polymer, and exposing the coated surface to a pattern of radiation to crosslink the polymer in a lithographic image. The functionalized polymer is a copolymer of an isoolefin of 4 to 7 carbon atoms and para-alkylstyrene, wherein the para-alkylstyrene is functionalized with a radiation reactive group at the para-alkyl group of the para-alkylstyrene.

7. 发明授权

US5585225A UV/EB curable butyl copolymers for lithographic and corrosion-resistant coating applications 失效
标题翻译：用于平版印刷和耐腐蚀涂层应用的UV / EB可固化丁基共聚物
公开(公告)号：US5585225A
公开(公告)日：1996-12-17
申请号：US298450
申请日：1994-10-27
申请人： Jay D. Audett , Kenneth O. McElrath
发明人： Jay D. Audett , Kenneth O. McElrath
IPC分类号： C09D123/22 , C08F2/46 , C08F8/00 , C08L23/22 , C09D123/02 , C09D125/00 , C09D125/18 , G03F7/028 , G03F7/038 , G03C5/00 , G03C1/52
CPC分类号： G03F7/0388 , C08F8/00 , C08L23/22 , Y02P20/582 , Y10S430/106 , Y10S430/114 , Y10S430/116 , Y10S430/117 , Y10S522/904 , Y10S522/905
摘要： A lithographic coating and method of framing a lithographic image are disclosed. The method comprises coating at least a portion of a surface of an article with a radiation-crosslinkable polymer, and exposing the coated surface to a pattern of radiation to crosslink the polymer in a lithographic image. The functionalized polymer is a copolymer of an isoolefin of 4 to 7 carbon atoms and para-alkylstyrene, wherein the para-alkylstyrene is functionalized with a radiation reactive group at the para-alkyl group of the para-alkylstyrene.
摘要翻译：公开了一种平版印刷涂层和一种构图平版印刷图像的方法。该方法包括用辐射可交联的聚合物涂覆制品的表面的至少一部分，并将涂覆的表面暴露于辐射图案以在光刻图像中交联聚合物。官能化聚合物是具有4至7个碳原子的异烯烃和对 - 烷基苯乙烯的共聚物，其中对烷基苯乙烯用对位烷基苯乙烯的对位烷基上的辐射反应性基团官能化。

8. 发明授权

US06654625B1 Mass transport limited in vivo analyte sensor 有权
标题翻译：大量运输有限的体内分析物传感器
公开(公告)号：US06654625B1
公开(公告)日：2003-11-25
申请号：US09595708
申请日：2000-06-16
申请人： James L. Say , Henning Sakslund , Michael F. Tomasco , Jay D. Audett , Hyun Cho , Duane O. Yamasaki , Adam Heller
发明人： James L. Say , Henning Sakslund , Michael F. Tomasco , Jay D. Audett , Hyun Cho , Duane O. Yamasaki , Adam Heller
IPC分类号： A61B505
CPC分类号： A61B5/14865 , A61B5/1486 , C12Q1/002 , C12Q1/006 , Y10S977/925
摘要： An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.
摘要翻译：包括工作电极和靠近工作电极的分析物响应感测层的体内电化学传感器。感测层在传感器的边缘处露出，其中传感器信号至少部分地通过质量传送分析物到感测层而受到限制。传感器被配置和布置成用于植入哺乳动物的身体以与哺乳动物体液接触。分析物经由传感器的边缘扩散到感测元件，从而限制分析物到传感元件的质量传递。这是因为传感器边缘的溶液接触表面积远小于感测层的开放面。

9. 发明授权

US5331049A Water-curable, hot melt adhesive composition 失效
标题翻译：水可固化，热熔胶组合物
公开(公告)号：US5331049A
公开(公告)日：1994-07-19
申请号：US542235
申请日：1990-06-22
申请人： Jay D. Audett , Mun F. Tse
发明人： Jay D. Audett , Mun F. Tse
IPC分类号： C09J143/04 , C09J151/06 , C08G81/02
CPC分类号： C09J151/06 , C09J143/04 , Y10T156/10
摘要： A water-curable hot melt adhesive system is disclosed. The system uses silane hydrolyzable functionality grafted onto an ethylene polymer component, and a tackifier compatible therewith. The ethylene polymer component is a copolymer of ethylene and a hydrocarbyl ester of an .alpha.,.beta.-ethylenically unsaturated carboxylic acid, and the tackifier component provides the adhesive with sufficient silanol condensation catalytic activity to accelerate water curing. The formulation is applied to a substrate surface as a hot melt at a moderate temperature, and subsequently cured by moisture or in a warm water bath. The invention also embodies structural compositions having glass, metallic or leather surfaces adhered with the adhesive and a method for making structural composites.
摘要翻译：公开了一种水可固化热熔粘合剂体系。该系统使用接枝到乙烯聚合物组分上的硅烷可水解官能团和与其相容的增粘剂。乙烯聚合物组分是乙烯和α，β-烯键式不饱和羧酸的烃基酯的共聚物，并且增粘剂组分为粘合剂提供足够的硅烷醇缩合催化活性以加速水固化。该配方在中等温度下作为热熔体施用于基材表面，随后通过水分或在温水浴中固化。本发明还体现了具有粘合剂的玻璃，金属或皮革表面的结构组合物以及制备结构复合材料的方法。

10. 发明授权

US5591551A UV/EB curable butyl copolymers for lithographic and corrosion-resistant coating applications 失效
标题翻译：用于平版印刷和耐腐蚀涂层应用的UV / EB可固化丁基共聚物
公开(公告)号：US5591551A
公开(公告)日：1997-01-07
申请号：US474870
申请日：1995-06-07
申请人： Jay D. Audett , Kenneth O. McElrath
发明人： Jay D. Audett , Kenneth O. McElrath
IPC分类号： C09D123/22 , C08F2/46 , C08F8/00 , C08L23/22 , C09D123/02 , C09D125/00 , C09D125/18 , G03F7/028 , G03F7/038 , G03C3/00
CPC分类号： G03F7/0388 , C08F8/00 , C08L23/22 , Y02P20/582 , Y10S430/106 , Y10S430/114 , Y10S430/116 , Y10S430/117 , Y10S522/904 , Y10S522/905
摘要： A lithographic coating and method of framing a lithographic image are disclosed. The method comprises coating at least a portion of a surface of an article with a radiation-crosslinkable polymer, and exposing the coated surface to a pattern of radiation to crosslink the polymer in a lithographic image. The functionalized polymer is a copolymer of an isoolefin of 4 to 7 carbon atoms and para-alkylstyrene, wherein the para-alkylstyrene is functionalized with a radiation reactive group at the para-alkyl group of the para-alkylstyrene.
摘要翻译：公开了一种平版印刷涂层和一种构图平版印刷图像的方法。该方法包括用辐射可交联的聚合物涂覆制品的表面的至少一部分，并将涂覆的表面暴露于辐射图案以在光刻图像中交联聚合物。官能化聚合物是具有4至7个碳原子的异烯烃和对 - 烷基苯乙烯的共聚物，其中对烷基苯乙烯用对位烷基苯乙烯的对位烷基上的辐射反应性基团官能化。

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