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1. 发明授权

US06175628B1 Method and system for broadcasting/distributing digital audio and video to a television 失效
标题翻译：将数字音视频广播/分发给电视的方法和系统
公开(公告)号：US06175628B1
公开(公告)日：2001-01-16
申请号：US09071368
申请日：1998-05-04
申请人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
发明人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
IPC分类号： H04L914
CPC分类号： H04N7/1675 , H04H20/61 , H04H60/23 , H04N7/162 , H04N21/4305 , H04N21/4341 , H04N21/4405
摘要： An audio input interface (122) receives a digital audio signal and identifies an audio bitstream which is optionally decrypted by a decryption unit (123), and decoded by an audio decoding unit (124). An audio digital to analog converter (126) converts the decoded audio bitstream to an analog audio signal which is optionally decrypted by an audio analog decryption unit (127). A video input interface (142) receives a digital video signal and identifies a video bitstream which is optionally decrypted by a video digital decryption unit (143), and decoded by a video decoding unit (144). A video digital to analog converter (146) converts the decoded video bitstream to an analog video signal that is optionally decrypted by a video analog decryption unit (147). An analog transmitter (150) mixes the analog audio signal and analog video signal and transmits an analog output signal to a television (110).
摘要翻译：音频输入接口（122）接收数字音频信号并识别由解密单元（123）可选解密的音频比特流，并由音频解码单元（124）解码。音频数模转换器（126）将解码的音频比特流转换为可选地由音频模拟解密单元（127）解密的模拟音频信号。视频输入接口（142）接收数字视频信号并识别由视频数字解密单元（143）可选解密的视频比特流，并由视频解码单元（144）解码。视频数/模转换器（146）将解码的视频比特流转换成视频模拟解密单元（147）任选解密的模拟视频信号。模拟发射机（150）混合模拟音频信号和模拟视频信号，并将模拟输出信号发送到电视机（110）。

2. 发明申请

US20160009696A1 COMPOUNDS INHIBITING LEUCINE-RICH REPEAT KINASE ENZYME ACTIVITY 有权
公开(公告)号：US20160009696A1
公开(公告)日：2016-01-14
申请号：US14772290
申请日：2014-02-27
申请人： Michael MILLER , Kallol BASU , Duane DEMONG , Jack SCOTT , Wei LI , Joel HARRIS , Andrew STAMFORD , Marc POIRIER , Paul TEMPEST , MERCK SHARP & DOHME CORP.
发明人： Michael Miller , Kallol Basu , Duane DeMong , Jack Scott , Wei Li , Joel Harris , Andrew Stamford , Marc Poirier , Paul Tempest
IPC分类号： C07D403/14 , C07D401/14 , C07D491/107 , C07D417/14 , C07D471/10 , C07D413/14 , C07D498/08
CPC分类号： C07D403/14 , A61K31/505 , A61K31/506 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/10 , C07D491/107 , C07D498/08
摘要： The present invention is directed to indazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.

3. 发明授权

US08026731B1 Method and apparatus for constructing images from measurements of impedance 有权
标题翻译：用于从阻抗测量构建图像的方法和装置
公开(公告)号：US08026731B1
公开(公告)日：2011-09-27
申请号：US11738404
申请日：2007-04-20
申请人： Jack Scott Emery
发明人： Jack Scott Emery
IPC分类号： G01R27/08 , G01R27/26 , G01N27/02
CPC分类号： A61B5/0536
摘要： Apparatus and methods are disclosed for obtaining an image of the impedance properties of an object by inferring a measure of straight-line path impedance along a plurality of paths from a plurality of current amplitude and phase measurements made between combinations of electrodes placed at selected points, and/or from measurements of the intensity of the electromagnetic signal emitted when an alternating current is made to resonate along the straight line path.
摘要翻译：公开的装置和方法用于通过从放置在选定点处的电极的组合之间进行的多个电流幅度和相位测量推断沿着多个路径的直线路径阻抗的测量来获得对象的阻抗特性的图像，和/或当使交流电沿着直线路径共振时发射的电磁信号的强度的测量。

4. 发明申请

US20080095740A1 PIPERIDINE DERIVATIVES USEFUL AS CCR5 ANTAGONISTS 审中-公开
标题翻译：哌啶衍生物作为CCR5拮抗剂有用
公开(公告)号：US20080095740A1
公开(公告)日：2008-04-24
申请号：US11925119
申请日：2007-10-26
申请人： Michael Miller , Jack Scott
发明人： Michael Miller , Jack Scott
IPC分类号： A61K31/506 , A61K31/538 , A61K31/551 , A61K31/675 , A61K31/7056 , A61K31/7068 , A61K31/7072 , A61K31/708 , A61K38/20 , A61P31/18
CPC分类号： C07D401/14
摘要： The present invention provides a compound of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein the various moieties are as defined in the specification. The present invention also provides pharmaceutical compositions containing the compound of this invention, and methods of treatment using the compound of this invention. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
摘要翻译：本发明提供下式的化合物或其药学上可接受的盐或溶剂合物，其中各种部分如说明书中所定义。本发明还提供含有本发明化合物的药物组合物和使用本发明化合物的治疗方法。本发明还涉及本发明化合物与一种或多种可用于治疗人类免疫缺陷病毒（HIV）的抗病毒剂或其它药剂的组合的用途。本发明还涉及本发明化合物单独或与另一种药剂组合用于治疗实体器官移植排斥，移植物抗宿主病，关节炎，类风湿性关节炎，炎症性肠病，特应性皮炎，牛皮癣，哮喘，过敏或多发性硬化。

5. 发明申请

US20070203183A1 Diaryl piperidines as CB1 modulators 审中-公开
标题翻译：二芳基哌啶作为CB1调节剂
公开(公告)号：US20070203183A1
公开(公告)日：2007-08-30
申请号：US11652227
申请日：2007-01-11
申请人： Jack Scott , Jay Weinstein , Michael Miller , Andrew Stamford , Eric Gilbert , Yan Xia , William Greenlee , Sarah Li
发明人： Jack Scott , Jay Weinstein , Michael Miller , Andrew Stamford , Eric Gilbert , Yan Xia , William Greenlee , Sarah Li
IPC分类号： A61K31/454 , C07D211/54 , A61K31/445 , C07D401/02
CPC分类号： C07D211/18 , C07D211/22 , C07D211/26 , C07D211/28 , C07D211/30 , C07D211/32 , C07D211/58 , C07D211/60 , C07D211/76 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/06 , C07D413/12 , C07D417/06 , C07D471/10
摘要： A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome (e.g., obesity, waist circumference, lipid profile, and insulin sensitivity), neuroinflammatory disorders, cognitive disorders, psychosis, addictive behavior, gastrointestinal disorders, and cardiovascular conditions.
摘要翻译：具有式（I）的通式结构的化合物或其药学上可接受的盐，溶剂化物或酯可用于治疗疾病，病症或病症如代谢综合征（例如，肥胖，腰围，脂质分布和胰岛素敏感性），神经炎症性疾病，认知障碍，精神病，成瘾行为，胃肠道疾病和心血管疾病。

6. 发明申请

US20060025441A1 Bipiperidinyl derivatives useful as inhibitors of chemokine receptors 失效
标题翻译：可用作趋化因子受体抑制剂的二哌啶基衍生物
公开(公告)号：US20060025441A1
公开(公告)日：2006-02-02
申请号：US10979075
申请日：2004-11-01
申请人： Michael Miller , Jack Scott
发明人： Michael Miller , Jack Scott
IPC分类号： A61K31/4545 , C07D401/04
CPC分类号： C07D413/14 , C07D401/14
摘要： In its many embodiments, the present invention provides a novel class of bipiperidinyl compounds as inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
摘要翻译：在其许多实施方案中，本发明提供了作为CCR5受体的抑制剂的新类型的联哌啶化合物，制备这些化合物的方法，含有一种或多种这样的化合物的药物组合物，制备包含一种或多种这样的化合物的药物制剂的方法，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CCR5相关的一种或多种疾病的方法。本发明还涉及本发明化合物与一种或多种可用于治疗人类免疫缺陷病毒（HIV）的抗病毒剂或其它药剂的组合的用途。本发明还涉及本发明化合物单独或与另一种药剂组合用于治疗实体器官移植排斥，移植物抗宿主病，关节炎，类风湿性关节炎，炎症性肠病，特应性皮炎，牛皮癣，哮喘，过敏或多发性硬化。

7. 发明授权

US06577354B2 Method and system for broadcasting digital audio and video to an analog wireless device 有权
公开(公告)号：US06577354B2
公开(公告)日：2003-06-10
申请号：US10021997
申请日：2001-12-13
申请人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
发明人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
IPC分类号： H04N538
CPC分类号： H04N7/1675 , H04H20/08 , H04H20/63 , H04H60/80 , H04N5/38 , H04N5/4401 , H04N5/602 , H04N21/43637 , H04N21/439
摘要： An audio input interface (122) receives a digital audio signal and identifies an audio bitstream which is optionally decrypted by a decryption unit (123), and decoded by an audio decoding unit (124). An audio digital to analog converter (126) converts the decoded audio bitstream to an analog audio signal which is optionally decrypted by an audio analog decryption unit (127). A video input interface (142) receives a digital video signal and identifies a video bitstream which is optionally decrypted by a video digital decryption unit (143), and decoded by a video decoding unit (144). A video digital to analog converter (146) converts the decoded video bitstream to an analog video signal that is optionally decrypted by a video analog decryption unit (147). An analog transmitter (150) mixes the analog audio signal and analog video signal and transmits an analog wireless output signal to an analog wireless device (110).

8. 发明授权

US06185305B2 Method and system for broadcasting digital audio to a radio 失效
标题翻译：将数字音频广播到广播的方法和系统
公开(公告)号：US06185305B2
公开(公告)日：2001-02-06
申请号：US09071047
申请日：1998-05-04
申请人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
发明人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
IPC分类号： H04L914
CPC分类号： H04H20/61 , H04H60/23 , H04R1/00 , H04R1/005
摘要： An audio input interface (122) receives a digital audio signal and identifies an audio bitstream which is optionally decrypted by a decryption unit (123), and decoded by an audio decoding unit (124). An audio digital to analog converter (126) converts the decoded audio bitstream to an analog audio signal which is optionally decrypted by an audio analog decryption unit (127). An analog transmitter (150) transmits the analog audio signal to a radio (110).
摘要翻译：音频输入接口（122）接收数字音频信号并识别由解密单元（123）可选解密的音频比特流，并由音频解码单元（124）解码。音频数模转换器（126）将解码的音频比特流转换为可选地由音频模拟解密单元（127）解密的模拟音频信号。模拟发射机（150）将模拟音频信号发送到无线电装置（110）。

9. 发明授权

US07647615B1 Method and system for distributing digital audio and video to an analog wireless device 失效
标题翻译：将数字音频和视频分发到模拟无线设备的方法和系统
公开(公告)号：US07647615B1
公开(公告)日：2010-01-12
申请号：US09071046
申请日：1998-05-04
申请人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
发明人： Jurgen Reinold , David Knappenberger , Mathew Cucuzella , Jack Scott Geranen , Jeff Lee , Michael E. Williams
IPC分类号： H04N60/32 , H04N7/173
CPC分类号： H04N7/1675 , H04N21/2368 , H04N21/4325 , H04N21/4341
摘要： An audio input interface (122) receives a digital audio signal and identifies an audio bitstream which is optionally decrypted by a decryption unit (123), and decoded by an audio decoding unit (124). An audio digital to analog converter (126) converts the decoded audio bitstream to an analog audio signal which is optionally decrypted by an audio analog decryption unit (127) and output by an audio output interface (128) to an analog wireline device (100). A video input interface (142) receives a digital video signal and identifies a video bitstream which is optionally decrypted by a video digital decryption unit (143), and decoded by a video decoding unit (144). A video digital to analog converter (146) converts the decoded video bitstream to an analog video signal that is optionally decrypted by a video analog decryption unit (147) and output by a video output interface (148) to the analog wireline device (100).
摘要翻译：音频输入接口（122）接收数字音频信号并识别由解密单元（123）可选解密的音频比特流，并由音频解码单元（124）解码。音频数模转换器（126）将解码的音频比特流转换成模拟音频信号，模拟音频信号可选地由音频模拟解密单元（127）解密并由音频输出接口（128）输出到模拟有线设备（100）。视频输入接口（142）接收数字视频信号并识别由视频数字解密单元（143）可选解密的视频比特流，并由视频解码单元（144）解码。视频数/模转换器（146）将解码视频比特流转换成视频模拟解密单元（147）可选地解密并由视频输出接口（148）输出到模拟有线设备（100）的模拟视频信号，。

10. 发明申请

US20060241121A1 Substituted piperazines as CB1 antagonists 失效
标题翻译：取代的哌嗪作为CB1拮抗剂
公开(公告)号：US20060241121A1
公开(公告)日：2006-10-26
申请号：US11292264
申请日：2005-12-01
申请人： William Greenlee , Jay Weinstein , Eric Gilbert , Michael Miller , Jack Scott , Andrew Stamford
发明人： William Greenlee , Jay Weinstein , Eric Gilbert , Michael Miller , Jack Scott , Andrew Stamford
IPC分类号： A61K31/496 , A61K31/495 , C07D403/04 , C07D241/04
CPC分类号： C07D241/04 , C07D401/04 , C07D401/06 , C07D401/10 , C07D401/12 , C07D403/06 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/06 , C07D405/08 , C07D405/12 , C07D409/04 , C07D409/06 , C07D409/12 , C07D409/14 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/10
摘要： Compounds of Formula (I): or pharmaceutically acceptable salts, solvates, or esters thereof, are useful in treating diseases or conditions mediated by CB1 receptors, such as metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, addiction (e.g., smoking cessation), gastrointestinal disorders, and cardiovascular conditions.
摘要翻译：式（I）化合物或其药学上可接受的盐，溶剂合物或酯可用于治疗由CB1受体介导的疾病或病症，例如代谢综合征和肥胖症，神经炎症性疾病，认知障碍精神病，成瘾（如戒烟），胃肠道疾病和心血管疾病。

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