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1. 发明申请

US20130345408A1 ANTIBODY AGAINST AMYLOID PRECURSOR PROTEIN SIGNAL PEPTIDE 有权
标题翻译：抗体蛋白前体蛋白信号肽抗体
公开(公告)号：US20130345408A1
公开(公告)日：2013-12-26
申请号：US13978584
申请日：2012-01-06
申请人： Hitoshi Fukushima , Masato Hanamura , Mikio Niwa , Masaji Okamoto , Tomoko Naoe , Tetsuhiko Yoshida
发明人： Hitoshi Fukushima , Masato Hanamura , Mikio Niwa , Masaji Okamoto , Tomoko Naoe , Tetsuhiko Yoshida
IPC分类号： C07K16/18
CPC分类号： C07K16/18 , C12N5/12
摘要： An advantage of some aspects of the invention is to provide an antibody against an amyloid precursor protein signal peptide. The invention provides an amyloid precursor protein signal peptide.
摘要翻译：本发明的一些方面的优点是提供抗淀粉样蛋白前体蛋白信号肽的抗体。本发明提供淀粉样蛋白前体蛋白信号肽。

2. 发明授权

US07998413B2 Biosensor and method of manufacturing biosensor 有权
标题翻译：生物传感器和生物传感器的制造方法
公开(公告)号：US07998413B2
公开(公告)日：2011-08-16
申请号：US12216203
申请日：2008-07-01
申请人： Hitoshi Fukushima , Takayuki Kondo
发明人： Hitoshi Fukushima , Takayuki Kondo
IPC分类号： G01N21/00 , G02B6/00 , G01N33/53
CPC分类号： G01N21/6452 , G01N21/553 , G01N21/6428 , G01N21/6454
摘要： Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.
摘要翻译：本发明的方面可以是一种廉价的生物传感器，其能够在短时间内测量多个样品，并且仅适合于一次使用（一次性）。根据本发明的生物传感器可以包括透光基板，设置在透光基板的一个面上的探针固定区域，设置在从其背面照射探针固定区域的基板的另一面上的发光元件以及设置在基板的另一面上的光接收元件，其检测来自探针固定区域的背侧的反射光的光强度。由此，能够得到在一个基板上形成的生物传感器。

3. 发明申请

US20100264024A1 BIOCHIP, BIOSENSOR AND INSPECTION SYSTEM 有权
标题翻译：生物传感器，生物传感器和检测系统
公开(公告)号：US20100264024A1
公开(公告)日：2010-10-21
申请号：US11617267
申请日：2006-12-28
申请人： Hitoshi FUKUSHIMA
发明人： Hitoshi FUKUSHIMA
IPC分类号： G01N27/26
CPC分类号： B82Y30/00 , B82Y15/00 , G01N27/4145
摘要： A biochip, includes: an ink-jet head portion detachably mountable to a biosensor; a sensing electrode formed with a work electrode, a reference electrode, and a counter electrode; and a thin film transistor.
摘要翻译：生物芯片包括：可拆卸地安装到生物传感器的喷墨头部; 形成有工作电极，参考电极和对电极的感测电极; 和薄膜晶体管。

4. 发明授权

US07491496B2 Method for immobilizing nucleic acid and method for manufacturing biosensor using the same method 失效
标题翻译：用于固定核酸的方法和使用相同方法制造生物传感器的方法
公开(公告)号：US07491496B2
公开(公告)日：2009-02-17
申请号：US11090238
申请日：2005-03-28
申请人： Hiroshi Takiguchi , Hitoshi Fukushima
发明人： Hiroshi Takiguchi , Hitoshi Fukushima
IPC分类号： C12Q1/68 , C12M1/00
CPC分类号： B82Y30/00 , C12Q1/6832 , C12Q2565/518 , C12Q2527/125 , C12Q2525/197
摘要： A method is provided to enable high-density absorption when immobilizing nucleic acid probes onto a solid support surface by suppressing electrostatic repulsion among the nucleic acids. A nucleic acid immobilization method to immobilize a nucleic acid onto a solid support, includes: preparing a solution containing a probe molecule which includes a nucleic acid, a spacer molecule, and at least one kind of a divalent cation; and contacting the solution with the solid support for incubation.
摘要翻译：提供了一种通过抑制核酸之间的静电排斥将核酸探针固定在固体支持物表面上以实现高密度吸收的方法。将核酸固定在固体支持体上的核酸固定方法包括：制备含有探针分子的溶液，所述探针分子包括核酸，间隔子分子和至少一种二价阳离子; 并将溶液与固体支持物接触以进行孵育。

5. 发明授权

US07407628B2 Biosensor and method of manufacturing biosensor 失效
公开(公告)号：US07407628B2
公开(公告)日：2008-08-05
申请号：US10911627
申请日：2004-08-05
申请人： Hitoshi Fukushima , Takayuki Kondo
发明人： Hitoshi Fukushima , Takayuki Kondo
IPC分类号： G01N21/00 , G01N33/53
CPC分类号： G01N21/6452 , G01N21/553 , G01N21/6428 , G01N21/6454
摘要： Aspects of the invention can be an inexpensive biosensor capable of measuring a number of samples in a short time, and suitable for only one-time use (expendable). The biosensor according to the invention can include a light transmissive substrate, a probe fixing region provided on one face of the light transmissive substrate, a light emitting element provided on the other face of the substrate that irradiates the probe fixing region from the back side thereof, and a light receiving element provided on the other face of the substrate that detects the light intensity of the reflected light from the back side of the probe fixing region. Thereby, a biosensor formed in one substrate can be obtained.

6. 发明授权

US06762050B2 Manufacture of a microsensor device and a method for evaluating the function of a liquid by the use thereof 有权
标题翻译：微传感器装置的制造和使用该液体的功能的评价方法
公开(公告)号：US06762050B2
公开(公告)日：2004-07-13
申请号：US09870588
申请日：2001-06-01
申请人： Hitoshi Fukushima , Tatsuya Shimoda , Hywel Morgan
发明人： Hitoshi Fukushima , Tatsuya Shimoda , Hywel Morgan
IPC分类号： C12M136
CPC分类号： G01N33/54366 , B01J2219/00378 , B01J2219/00653 , B01J2219/00659 , B41J2/01 , C12Q1/6834 , C40B60/14
摘要： In order to form organic thin films on electrodes, a solution of a material for the organic thin film is accurately printed via an ink-jet onto the surface of microelectrodes as required, thereby producing a high density array of microelectrodes. Further, a solution of a sample substance or a liquid substance to be sensed is ejected into air via an ink-jet nozzle to fall to the surface of organic thin membranes on the microelectrodes so that the sample can be evaluated.
摘要翻译：为了在电极上形成有机薄膜，根据需要，通过喷墨将有机薄膜的材料溶液精确地印刷到微电极的表面上，从而产生高密度的微电极阵列。此外，待检测的样品物质或液体物质的溶液通过喷墨嘴喷射到空气中以落在微电极上的有机薄膜表面上，从而可以评估样品。

7. 发明授权

US4884081A Magnetic ink and method of printing 失效
标题翻译：磁性墨水和印刷方法
公开(公告)号：US4884081A
公开(公告)日：1989-11-28
申请号：US199482
申请日：1988-05-27
申请人： Hitoshi Fukushima , Katsumori Takei , Kohei Iwamoto , Hiroto Nakamura
发明人： Hitoshi Fukushima , Katsumori Takei , Kohei Iwamoto , Hiroto Nakamura
IPC分类号： B41J2/315 , B41J2/385 , B41J31/05 , B41M5/26 , B41M5/382 , B41N1/12 , C09D5/23 , C09D11/02
CPC分类号： B41M5/38285 , B41J2/315 , B82Y15/00
摘要： A thermal transfer magnetic ink, ink sheet and method of printing with the magnetic ink and apparatus which will print high quality images and characters. The heat-fusible magnetic ink transfer sheet includes a heat-fusible magnetic ink layer disposed on a heat resistant support film. The magnetic ink layer includes minute magnetic particles dispersed in a binder and has a surface tension lower than about 20 dynes/cm when melted. The magnetic properties of the ink combined with the melted ink's surface tension, permit avoiding contact between the ink transfer sheet and the recording medium. A magnetic field pulls the ink melted by a print head off of the support film so that the melted ink flies from the ink transfer sheet to the recording medium.
摘要翻译：热转印磁性墨水，油墨纸和使用磁性墨水和设备印刷的方法，其将打印高质量的图像和字符。热熔性墨水转印片包括设置在耐热支撑膜上的热熔性墨水层。磁性墨层包括分散在粘合剂中的微小磁性颗粒，并且当熔化时表面张力低于约20达因/厘米。墨水的磁性能与熔融墨水的表面张力结合，可以避免墨水转印片材和记录介质之间的接触。磁场将由打印头熔化的油墨从支撑膜拉出，使得熔融的油墨从油墨转印纸飞到记录介质。

8. 发明申请

US20140072592A1 METHOD OF PREPARING ANTIGEN FOR ACQUIRING ANTI-HYDROPHOBIC PEPTIDE ANTIBODY 有权
标题翻译：制备用于获得抗血栓肽抗体的抗原的方法
公开(公告)号：US20140072592A1
公开(公告)日：2014-03-13
申请号：US13978419
申请日：2012-01-06
申请人： Masaji Okamoto , Masato Hanamura , Hitoshi Fukushima , Tetsuhiko Yoshida
发明人： Masaji Okamoto , Masato Hanamura , Hitoshi Fukushima , Tetsuhiko Yoshida
IPC分类号： G01N33/68 , C07K16/18 , C07K14/705 , C07K14/47 , C07K14/245 , C07K16/12 , C07K16/28
CPC分类号： G01N33/6896 , C07K14/245 , C07K14/4711 , C07K14/70596 , C07K16/1232 , C07K16/18 , C07K16/2896
摘要： The object of the present invention is to provide a method to obtain an antibody for a hydrophobic peptide, which can be used for general purposes easily and with great reliability. Also provided is a method for preparing an antigen characterized in that a hydrophobic peptide, which is unbound to carrier protein, is used as high-molecular-weight aggregates in an aqueous solution containing a nonionic surfactant.
摘要翻译：本发明的目的是提供一种获得疏水性肽抗体的方法，其可以容易且高可靠性地用于一般目的。还提供了制备抗原的方法，其特征在于将未结合载体蛋白的疏水性肽用作含有非离子表面活性剂的水溶液中的高分子量聚集体。

9. 发明授权

US08217857B2 Display, display method, and electronic device 有权
标题翻译：显示，显示方式和电子设备
公开(公告)号：US08217857B2
公开(公告)日：2012-07-10
申请号：US12043698
申请日：2008-03-06
申请人： Takeo Kawase , Takayuki Kondo , Hitoshi Fukushima , Yuji Shinohara
发明人： Takeo Kawase , Takayuki Kondo , Hitoshi Fukushima , Yuji Shinohara
IPC分类号： G09G3/19 , G09G3/30 , G09G3/10
CPC分类号： G09G3/3446 , G02F1/167 , G02F2203/34
摘要： A display, comprising: a planar display section; a pixel space provided next to a side adjacent to one surface of the display section and encapsulating a plurality of kinds of colorants, each kind having a different color; an accumulation section provided in the pixel space and accumulating the colorants; a separation system that separates a specific kind of colorant from the accumulated colorants in the accumulation section; a transfer system that selects at least one kind of colorant from the separated colorants and transfers this colorant to the side adjacent to the display section of the pixel space. The separation system performs separation utilizing the magnitude of a dielectrophoretic force generated in each colorant upon receipt of an alternating electric field of a specific frequency applied by this system, the magnitude varying depending on the kind of the colorant. A color of at least the one kind of colorant transferred by the transfer system is displayed at the display section.
摘要翻译：一种显示器，包括：平面显示部分; 设置在与显示部的一个表面相邻的一侧的像素空间，并且封装多种着色剂，每种着色剂具有不同的颜色; 设置在像素空间中并累积着色剂的累积部分; 分离系统，其将特定种类的着色剂与累积部分中的累积着色剂分离; 转移系统，其从分离的着色剂中选择至少一种着色剂并将该着色剂转移到与像素空间的显示部分相邻的一侧。分离系统在接收到由该系统施加的特定频率的交变电场时，利用每种着色剂中产生的介电电泳力的大小进行分离，其大小根据着色剂的种类而变化。在显示部分显示至少一种由转印系统转印的着色剂的颜色。

10. 发明授权

US07955705B2 Electronic device substrate, method for manufacturing substrate, compound used for substrate, method for manufacturing compound and polymerization initiator including compound 有权
标题翻译：电子器件基板，基板的制造方法，基板用化合物，化合物的制造方法以及包含化合物的聚合引发剂
公开(公告)号：US07955705B2
公开(公告)日：2011-06-07
申请号：US11739837
申请日：2007-04-25
申请人： Hitoshi Fukushima , Shinobu Yokokawa
发明人： Hitoshi Fukushima , Shinobu Yokokawa
IPC分类号： B32B15/04
CPC分类号： C08F291/00 , B82Y10/00 , C08F290/14 , C08F292/00 , C08F293/005 , H01L51/0075 , H01L51/0595 , Y10T428/31504 , Y10T428/31536 , Y10T428/31678
摘要： An electronic device substrate includes a substrate having at least one of a metal and a metal oxide on a surface thereof and an underlying layer having a compound expressed by a following general formula (1): wherein X presents one of a hydrogen atom and a protecting group; Y1 represents one of an oxygen atom, an alkylene group and —N(R1)—, in which R1 represents an alkyl group; Z1 represents a polymerization initiating group; n1 represents an integer from 1 to 4; and m1 represents an integer from 1 to 15.
摘要翻译：电子器件衬底包括其表面上具有金属和金属氧化物中的至少一种的衬底和具有由以下通式（1）表示的化合物的下层：其中X表示氢原子和保护基组; Y1表示氧原子，亚烷基和-N（R1） - 中的一个，其中R1表示烷基; Z1表示聚合引发基团; n1表示1〜4的整数， m1表示1〜15的整数。

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