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1. 发明申请

US20050239046A1 Method and apparatus for measuring changes in cell volume 审中-公开
标题翻译：用于测量细胞体积变化的方法和装置
公开(公告)号：US20050239046A1
公开(公告)日：2005-10-27
申请号：US11072732
申请日：2005-03-04
申请人： Frederick Sachs , Zonglu Hua , Stephen Besch , Harsh Chopra , Anthony Auerbach , Philip Gottlieb , Daniel Ateya
发明人： Frederick Sachs , Zonglu Hua , Stephen Besch , Harsh Chopra , Anthony Auerbach , Philip Gottlieb , Daniel Ateya
IPC分类号： C12Q1/00 , C12Q1/02 , G01N15/02 , G01N33/487 , G01N33/50 , G01N33/569
CPC分类号： G01N15/0266 , G01N33/5026 , G01N33/569
摘要： A method and apparatus for measuring changes in cell volume generally includes introducing cells into a chamber having a volume between 2 and 100 times the volume of the introduced cell. A first electrically conductive extracellular fluid is introduced into the chamber and a current is applied. The current flow is measured. The first fluid is exchanged with a second electrically conductive extracellular fluid and a current is applied. The current flow is measured. The first current flow result and the second current flow result are used in conjunction with known current flows to monitor changes in the volume corresponding to fluid flow between the cell and an extracellular fluid.
摘要翻译：用于测量细胞体积变化的方法和装置通常包括将细胞引入具有介入细胞体积的2至100倍的体积的室中。将第一导电细胞外液引入腔室并施加电流。测量电流。第一流体与第二导电细胞外液体交换，并且施加电流。测量电流。第一电流流动结果和第二电流流动结果与已知的电流一起使用，以监测对应于细胞和细胞外液体之间的流体流动的体积变化。

2. 发明申请

US20060261800A1 Selectively conductive structure 有权
标题翻译：选择导电结构
公开(公告)号：US20060261800A1
公开(公告)日：2006-11-23
申请号：US11355626
申请日：2006-02-16
申请人： Harsh Chopra , Zonglu Hua , Matthew Sullivan , Jason Armstrong
发明人： Harsh Chopra , Zonglu Hua , Matthew Sullivan , Jason Armstrong
IPC分类号： G01R13/04
CPC分类号： G01R33/093 , B82Y25/00 , G01R33/09
摘要： The invention includes a conductor with a first side and a second side. The conductor may be sized to have a cross-section diameter substantially similar to a Fermi wavelength of electrons in the conductor, the cross-section diameter being taken substantially perpendicular to a primary direction in which current could flow through the conductor. The conductor size may be selected so that when a magnetic field less than a threshold value is applied to the conductor, the first side of the conductor has a first magnetic state and the second side of the conductor has a second magnetic state. However, when a magnetic field of sufficient strength is applied to the magnetic conductor the first side and the second side will be caused to have the same magnetic state. The material of the conductor may be selected from those for which magnetoresistance magnitude of the material oscillates as a function of the material's cross-sectional area, and the cross-sectional area of the conductor may be selected to correspond to a peak of the function.
摘要翻译：本发明包括具有第一侧和第二侧的导体。导体的尺寸可以具有与导体中的电子的费米波长基本相似的截面直径，其截面直径基本上垂直于电流可以流过导体的主要方向。可以选择导体尺寸，使得当小于阈值的磁场被施加到导体时，导体的第一侧具有第一磁状态，并且导体的第二侧具有第二磁状态。然而，当向磁导体施加足够强度的磁场时，将使第一侧和第二侧具有相同的磁状态。导体的材料可以选自材料的磁阻大小作为材料的横截面积的函数振荡的材料，并且导体的横截面面积可以被选择为对应于功能的峰值。

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