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    • 2. 发明申请
      US20080183126A1 APPARATUS AND METHODS FOR EARLY STAGE PERITONITIS DETECTION AND FOR IN VIVO TESTING OF BODILY FLUID 有权
    • APPARATUS AND METHODS FOR EARLY STAGE PERITONITIS DETECTION AND FOR IN VIVO TESTING OF BODILY FLUID
    • 用于早期阶段血液透析检测和体液检测的装置和方法
    • US20080183126A1
    • 2008-07-31
    • US12020171
    • 2008-01-25
    • Frank J. Landherr , Jay M. Lan
    • Frank J. Landherr , Jay M. Lan
    • A61M1/28
    • A61B5/0059 , A61M1/28 , A61M1/285 , A61M2205/331
    • The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of peritonitis, based on optical characteristics of the effluent resolved at cellular scales of distance. For example, according to one aspect of the invention, an APD machine includes, in an effluent flow path, apparatus for early stage peritonitis detection comprising an illumination source and a detector. The source is arranged to illuminate peritoneal effluent in a chamber that forms part of the flow path, and the detector is arranged to detect illuminant scattered by the effluent. The detector detects that reflected or scattered illuminant at a cellular scale of resolution, e.g., on a scale such that separate cellular-sized biological (or other) components in the effluent can be distinguished from one another based on scattering events detected by the detector. Other aspects of the invention provide automated medical testing methods and apparatus that detect the onset of peritonitis and other bodily conditions by testing fluids in the body in vivo, e.g., the patient's peritoneum. Such apparatus and methods utilize a first fiber optic bundle to carry illuminant from a source of the type described above into a bodily organ or cavity, and a second fiber optic bundle to carry illuminant scattered by fluid in that organ or cavity to a detector as described above.
    • 本发明尤其提供了一种自动化医疗方法和装置，其基于流出物的光学特性来测定PD流出物在流动路径（例如，使用APD系统或CAPD装置）中以检测例如腹膜炎的发作， 在距离的细胞尺度。 例如，根据本发明的一个方面，APD机器在流出物流路中包括用于早期腹膜炎检测的装置，其包括照明源和检测器。 来源设置为照射形成流路的一部分的室中的腹膜流出物，并且检测器被布置成检测由流出物散射的发光体。 检测器以分辨率的细胞尺度（例如，尺度）检测反射或散射的光源，使得流出物中的分离的细胞大小的生物（或其他）组分可以基于由检测器检测到的散射事件彼此区分开。 本发明的其它方面提供了自动化的医学测试方法和装置，其通过在体内测试体内的流体（例如患者的腹膜）来检测腹膜炎和其他身体状况的发作。 这种设备和方法利用第一光纤束将源自上述类型的光源的发光体携带到身体器官或空腔中，以及第二光纤束将第二光纤束携带由该器官或空腔中的流体散射的发光体到所述的检测器 以上。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 4. 发明授权
      US08801652B2 Early stage peritonitis detection apparatus and methods 有权
    • Early stage peritonitis detection apparatus and methods
    • 早期腹膜炎检测仪及方法
    • US08801652B2
    • 2014-08-12
    • US11880656
    • 2007-07-23
    • Frank J. Landherr , Lynn E. Jensen , Jay M. Lan
    • Frank J. Landherr , Lynn E. Jensen , Jay M. Lan
    • A61M1/00 , G06F19/00 , B01D61/00
    • A61M1/28 , A61M2205/331
    • The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of peritonitis, based on optical characteristics of the effluent resolved at cellular scales of distance. For example, according to one aspect of the invention, an APD machine includes, in an effluent flow path, apparatus for early stage peritonitis detection comprising an illumination source and a detector. The source is arranged to illuminate peritoneal effluent in a chamber that forms part of the flow path, and the detector is arranged to detect illuminant scattered by the effluent. The detector detects that reflected or scattered illuminant at a cellular scale of resolution, e.g., on a scale such that separate cellular-sized biological (or other) components in the effluent can be distinguished from one another based on scattering events detected by the detector.
    • 本发明尤其提供了一种自动化医疗方法和装置，其基于流出物的光学特性来测定PD流出物在流动路径（例如，使用APD系统或CAPD装置）中以检测例如腹膜炎的发作， 在距离的细胞尺度。 例如，根据本发明的一个方面，APD机器在流出物流路中包括用于早期腹膜炎检测的装置，其包括照明源和检测器。 来源设置为照射形成流路的一部分的室中的腹膜流出物，并且检测器被布置成检测由流出物散射的发光体。 检测器以分辨率的细胞尺度（例如，尺度）检测反射或散射的光源，使得流出物中的分离的细胞大小的生物（或其他）组分可以基于由检测器检测到的散射事件彼此区分开。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Espacenet 法律信息 同族专利 专利引用
    • 5. 发明授权
      US08728023B2 Apparatus and methods for early stage peritonitis detection including self-cleaning effluent chamber 有权
    • Apparatus and methods for early stage peritonitis detection including self-cleaning effluent chamber
    • 用于早期腹膜炎检测的装置和方法，包括自清流出室
    • US08728023B2
    • 2014-05-20
    • US12020192
    • 2008-01-25
    • Frank J. Landherr , Jay M. Lan
    • Frank J. Landherr , Jay M. Lan
    • G06F19/00 , A61M1/00 , B01D61/00
    • A61B5/0059 , A61M1/28 , A61M1/285 , A61M2205/331
    • The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of peritonitis, based on optical characteristics of the effluent resolved at cellular scales of distance. For example, according to one aspect of the invention, an APD machine includes, in an effluent flow path, apparatus for early stage peritonitis detection comprising an illumination source and a detector. The source is arranged to illuminate peritoneal effluent in a chamber that forms part of the flow path, and the detector is arranged to detect illuminant scattered by the effluent. The detector detects that reflected or scattered illuminant at a cellular scale of resolution, e.g., on a scale such that separate cellular-sized biological (or other) components in the effluent can be distinguished from one another based on scattering events detected by the detector. According to aspects of the invention, the chamber can utilize a deflector to effect turbulent flow for purposes of cleaning biological and other materials from the chamber walls.
    • 本发明尤其提供了一种自动化医疗方法和装置，其基于流出物的光学特性来测定PD流出物在流动路径（例如，使用APD系统或CAPD装置）中以检测例如腹膜炎的发作， 在距离的细胞尺度。 例如，根据本发明的一个方面，APD机器在流出物流路中包括用于早期腹膜炎检测的装置，其包括照明源和检测器。 来源设置为照射形成流路的一部分的室中的腹膜流出物，并且检测器被布置成检测由流出物散射的发光体。 检测器以分辨率的细胞尺度（例如，尺度）检测反射或散射的光源，使得流出物中的分离的细胞大小的生物（或其他）组分可以基于由检测器检测到的散射事件彼此区分开。 根据本发明的方面，室可以利用偏转器来实现湍流，以便从室壁清洁生物材料和其它材料。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Espacenet 法律信息 同族专利 专利引用
    • 7. 发明申请
      US20080183127A1 APPARATUS AND METHODS FOR EARLY STAGE PERITONITIS DETECTION INCLUDING SELF-CLEANING EFFLUENT CHAMBER 有权
    • APPARATUS AND METHODS FOR EARLY STAGE PERITONITIS DETECTION INCLUDING SELF-CLEANING EFFLUENT CHAMBER
    • 用于早期阶段周期检测的装置和方法，包括自清洁液体室
    • US20080183127A1
    • 2008-07-31
    • US12020192
    • 2008-01-25
    • Frank J. Landherr , Jay M. Lan
    • Frank J. Landherr , Jay M. Lan
    • A61M1/28
    • A61B5/0059 , A61M1/28 , A61M1/285 , A61M2205/331
    • The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of peritonitis, based on optical characteristics of the effluent resolved at cellular scales of distance. For example, according to one aspect of the invention, an APD machine includes, in an effluent flow path, apparatus for early stage peritonitis detection comprising an illumination source and a detector. The source is arranged to illuminate peritoneal effluent in a chamber that forms part of the flow path, and the detector is arranged to detect illuminant scattered by the effluent. The detector detects that reflected or scattered illuminant at a cellular scale of resolution, e.g., on a scale such that separate cellular-sized biological (or other) components in the effluent can be distinguished from one another based on scattering events detected by the detector. According to aspects of the invention, the chamber can utilize a deflector to effect turbulent flow for purposes of cleaning biological and other materials from the chamber walls.
    • 本发明尤其提供了一种自动化医疗方法和装置，其基于流出物的光学特性来测定PD流出物在流动路径（例如，使用APD系统或CAPD设置））以检测例如腹膜炎的发作， 在距离的细胞尺度。 例如，根据本发明的一个方面，APD机器在流出物流路中包括用于早期腹膜炎检测的装置，其包括照明源和检测器。 来源设置为照射形成流路的一部分的室中的腹膜流出物，并且检测器被布置成检测由流出物散射的发光体。 检测器以分辨率的细胞尺度（例如，尺度）检测反射或散射的光源，使得流出物中的分离的细胞大小的生物（或其他）组分可以基于由检测器检测到的散射事件彼此区分开。 根据本发明的方面，室可以利用偏转器来实现湍流，以便从室壁清洁生物材料和其它材料。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Global Dossier Espacenet 法律信息 同族专利 专利引用
    • 8. 发明授权
      US08267885B2 Methods and apparatus for delivering peritoneal dialysis (PD) solution with a peristaltic pump 有权
    • Methods and apparatus for delivering peritoneal dialysis (PD) solution with a peristaltic pump
    • 用蠕动泵输送腹膜透析（PD）溶液的方法和装置
    • US08267885B2
    • 2012-09-18
    • US12347663
    • 2008-12-31
    • Frank J. Landherr , Jay M. Lan
    • Frank J. Landherr , Jay M. Lan
    • A61M1/00
    • A61M1/28
    • In one aspect, the invention provides methods and apparatus for delivering peritoneal dialysis (PD) solution (or other fluids), from a supply to a patient. A first pump, in fluid coupling with the supply, delivers PD solution from the supply to a “mesne” (or intermediate) measuring element, and generates signals indicative of a volume of that delivered PD solution. The mesne measuring element, in fluid coupling with the first pump, generates signals indicative of a volume of PD solution received from that pump. A second pump, fluidly coupled to the mesne measuring element, routes PD solution from the mesne measuring element for delivery to the patient.
    • 一方面，本发明提供了用于从供应物向患者递送腹膜透析（PD）溶液（或其它流体）的方法和装置。 与电源流体耦合的第一个泵将PD解决方案从电源传递到“中间”（或中间）测量元件，并产生指示输送的PD溶液的体积的信号。 与第一泵流体联接的中间测量元件产生指示从该泵接收的PD溶液的体积的信号。 液体耦合到中间测量元件的第二泵将PD溶液从测量元件传送到患者。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Espacenet 法律信息 同族专利 专利引用
    • 10. 发明授权
      US08777891B2 Apparatus and methods for early stage peritonitis detection and for in vivo testing of bodily fluid 有权
    • Apparatus and methods for early stage peritonitis detection and for in vivo testing of bodily fluid
    • 用于早期腹膜炎检测和体内体液检测的装置和方法
    • US08777891B2
    • 2014-07-15
    • US12020171
    • 2008-01-25
    • Frank J. Landherr , Jay M. Lan
    • Frank J. Landherr , Jay M. Lan
    • G06F19/00 , A61M1/00 , B01D61/00
    • A61B5/0059 , A61M1/28 , A61M1/285 , A61M2205/331
    • The invention provides, inter alia, automated medical methods and apparatus that test PD effluent in a flow path (e.g., with an APD system or CAPD setup) to detect, for example, the onset of peritonitis, based on optical characteristics of the effluent resolved at cellular scales of distance. For example, according to one aspect of the invention, an APD machine includes, in an effluent flow path, apparatus for early stage peritonitis detection comprising an illumination source and a detector. The source is arranged to illuminate peritoneal effluent in a chamber that forms part of the flow path, and the detector is arranged to detect illuminant scattered by the effluent. The detector detects that reflected or scattered illuminant at a cellular scale of resolution, e.g., on a scale such that separate cellular-sized biological (or other) components in the effluent can be distinguished from one another based on scattering events detected by the detector. Other aspects of the invention provide automated medical testing methods and apparatus that detect the onset of peritonitis and other bodily conditions by testing fluids in the body in vivo, e.g., the patient's peritoneum. Such apparatus and methods utilize a first fiber optic bundle to carry illuminant from a source of the type described above into a bodily organ or cavity, and a second fiber optic bundle to carry illuminant scattered by fluid in that organ or cavity to a detector as described above.
    • 本发明尤其提供了一种自动化医疗方法和装置，其基于流出物的光学特性来测定PD流出物在流动路径（例如，使用APD系统或CAPD装置）中以检测例如腹膜炎的发作， 在距离的细胞尺度。 例如，根据本发明的一个方面，APD机器在流出物流路中包括用于早期腹膜炎检测的装置，其包括照明源和检测器。 来源设置为照射形成流路的一部分的室中的腹膜流出物，并且检测器被布置成检测由流出物散射的发光体。 检测器以分辨率的细胞尺度（例如，尺度）检测反射或散射的光源，使得流出物中的分离的细胞大小的生物（或其他）组分可以基于由检测器检测到的散射事件彼此区分开。 本发明的其它方面提供了自动化的医学测试方法和装置，其通过在体内测试体内的流体（例如患者的腹膜）来检测腹膜炎和其他身体状况的发作。 这种设备和方法利用第一光纤束将源自上述类型的光源的发光体携带到身体器官或空腔中，以及第二光纤束将第二光纤束携带由该器官或空腔中的流体散射的发光体到所述的检测器 以上。
    • 基本信息 添加关注 加入工作空间 PDF全文 PDF下载 全文下载 相似专利 双屏查看 权利要求书 说明书全文 Espacenet 法律信息 同族专利 专利引用
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