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    • 9. 发明授权
    • Blood bag system for separation and isolation of neocytes and gerocytes
    • 用于分离和分离新细胞和巨细胞的血袋系统
    • US5300060A
    • 1994-04-05
    • US772402
    • 1991-10-07
    • Edward J. Nelson
    • Edward J. Nelson
    • A61J1/10A61M1/02A61M39/22A61M5/00
    • A61M1/0209A61M1/0218A61M2039/222A61M2202/0429A61M2202/0431A61M2202/0439
    • A generally flat, elongated edge-sealed polymeric blood bag having a length to width ratio of at least 2 to 1 and one end portion in tapering communication with a connected single tubing which in turn is in closed communication via a Y-connector with both a bag access port and at least one other Y-connector. The second Y-connector is in closed communication with at least one auxiliary bag, preferably two auxiliary bags. Once the upper neocyte portion is expressed from the elongated blood bag the lower, more dense gerocytes can be saved in the original elongated bag or expressed into another connected bag via the Y-connector assembly for subsequent use or storage. The bag system is especially useful for separating and isolating both components of a neocyte/gerocyte red blood cell mixture in an open system and for providing a means for saving the otherwise discarded gerocytes for subsequent use. A physiological solution can be introduced via the Y-connector assemblies into the elongated bag to reconstitute the dense gerocytes.
    • 一种长度与宽度比至少为2比1的一般扁平细长的边缘密封的聚合血袋,以及一个与连接的单个管道呈锥形连通的端部,该连接的单一管道又通过Y型连接器与 袋入口和至少一个其他Y型连接器。 第二个Y型连接器与至少一个辅助袋,最好是两个辅助袋密封连通。 一旦从细长的血袋表达上部新细胞部分,下部更密集的巨细胞可以保存在原始细长的袋子中,或者通过Y型连接器组件被表达到另一个连接的袋子中以供后续使用或储存。 袋系统特别可用于在开放系统中分离和分离新细胞/巨细胞红血细胞混合物的两种组分,并提供用于储存另外丢弃的大豆细胞以供随后使用的方法。 可以通过Y型连接器组件将生理溶液引入细长袋中以重构密集的细胞。