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1. 发明申请

US20060124859A1 Multimode ionization mode separator 有权
标题翻译：多模电离模式分离器
公开(公告)号：US20060124859A1
公开(公告)日：2006-06-15
申请号：US11349469
申请日：2006-02-06
申请人： Steven Fischer , Darrell Gourley , Patricia Cormia
发明人： Steven Fischer , Darrell Gourley , Patricia Cormia
IPC分类号： H01J27/24
CPC分类号： H01J49/107 , H01J49/06 , H01J49/165
摘要： A multimode ionization source includes an electrospray ionization source for providing a charged aerosol, an atmospheric pressure ionization source downstream from the electrospray ionization source for further ionizing said charged aerosol, and a mode separator, or mask, situated so as to separate a portion of the charged aerosol and prevent the portion from being exposed to the atmospheric pressure ionization source.
摘要翻译：多模电离源包括用于提供带电气溶胶的电喷雾离子化源，用于电喷雾离子化源的下游的大气压电离源，用于进一步电离所述带电气体，以及模式分离器或掩模，并且防止该部分暴露于大气压电离源。

2. 发明申请

US20060076505A1 Ion sampling for APPI mass spectrometry 有权
公开(公告)号：US20060076505A1
公开(公告)日：2006-04-13
申请号：US11290187
申请日：2005-11-30
申请人： Steven Fischer , Darrell Gourley , Patricia Cormia , James Bertsch , Karl Hanold
发明人： Steven Fischer , Darrell Gourley , Patricia Cormia , James Bertsch , Karl Hanold
IPC分类号： H01J27/24
CPC分类号： G01N30/7253 , H01J27/24 , H01J49/0431 , H01J49/145 , H01J49/162
摘要： An atmospheric pressure ion source, e.g. for a mass spectrometer, that produces ions by atmospheric pressure photoionization (APPI). It includes a vaporizer, a photon source for photoionizing vapor molecules upon exit from the vaporizer, a passageway for transporting ions to, for example, a mass spectrometer system, and a means for directing the ions into the passageway. The center axis of the vaporizer and the center axis of the passageway form an angle that may be about 90 degrees. Included in the invention is a method for creating ions by atmospheric pressure photoionization along an axis and directing them into a passageway oriented at an angle to that axis.

3. 发明申请

US20050211911A1 Apparatus and method for sensor control and feedback 有权
标题翻译：传感器控制和反馈的装置和方法
公开(公告)号：US20050211911A1
公开(公告)日：2005-09-29
申请号：US11067136
申请日：2005-02-25
申请人： Steven Fischer , Darrell Gourley , Glen Ingle , Timothy Joyce
发明人： Steven Fischer , Darrell Gourley , Glen Ingle , Timothy Joyce
IPC分类号： H01J27/00 , H01J49/10
CPC分类号： H01J49/04 , H01J49/10 , H01J49/107 , H01J49/165
摘要： The present invention relates to an apparatus and method for use with a mass spectrometry system. The invention provides an ion source, infrared emitter and sensor with closed control feedback loop coupled to the infrared emitter. Methods of control and heating using the apparatus of the present invention are also disclosed.
摘要翻译：本发明涉及一种与质谱系统一起使用的装置和方法。本发明提供一种离子源，红外发射器和传感器，其具有耦合到红外发射器的闭合控制反馈环路。还公开了使用本发明的设备进行控制和加热的方法。

4. 发明申请

US20070023675A1 Multimode ionization source 有权
标题翻译：多模电离源
公开(公告)号：US20070023675A1
公开(公告)日：2007-02-01
申请号：US11444095
申请日：2006-05-31
申请人： Steven Fischer , Darrell Gourley , James Bertsch
发明人： Steven Fischer , Darrell Gourley , James Bertsch
IPC分类号： H01J27/24
CPC分类号： H01J49/107 , H01J49/0445 , H01J49/162 , H01J49/165 , H01J49/168
摘要： The present invention provides an apparatus and method for use with a mass spectrometer. The multimode ionization source of the present invention provides one or more atmospheric pressure ionization sources (e.g., electrospray, atmospheric pressure chemical ionization and/or atmospheric pressure photoionization) for ionizing molecules. A method of producing ions using the multimode ionization source is also disclosed. The apparatus and method provide the advantages of the combined ion sources without the inherent disadvantages of the individual sources. In an embodiment, the multimode ionization source includes an infrared emitter enclosed in an inner chamber for drying a charged aerosol. ESI/APCI multimode sources may include a corona needle shield and/or an auxiliary electrode.
摘要翻译：本发明提供了一种与质谱仪一起使用的装置和方法。本发明的多模电离源提供用于电离分子的一个或多个大气压电离源（例如电喷雾，大气压化学电离和/或大气压光电离）。还公开了使用多模电离源产生离子的方法。该装置和方法提供了组合离子源的优点，而没有各个源的固有缺点。在一个实施例中，多模式电离源包括封闭在内室中用于干燥带电气溶胶的红外发射器。 ESI / APCI多模式源可以包括电晕针护罩和/或辅助电极。

5. 发明申请

US20060086908A1 MULTIMODE IONIZATION MODE SEPARATOR 有权
标题翻译：多模式离子化模式分离器
公开(公告)号：US20060086908A1
公开(公告)日：2006-04-27
申请号：US10971658
申请日：2004-10-22
申请人： Steven Fischer , Darrell Gourley , Patricia Cormia
发明人： Steven Fischer , Darrell Gourley , Patricia Cormia
IPC分类号： H01J49/10
CPC分类号： H01J49/107 , H01J49/06 , H01J49/165
摘要： A multimode ionization source includes an electrospray ionization source for providing a charged aerosol, an atmospheric pressure ionization source downstream from the electrospray ionization source for further ionizing said charged aerosol, and a mode separator, or mask, situated so as to separate a portion of the charged aerosol and prevent the portion from being exposed to the atmospheric pressure ionization source.
摘要翻译：多模电离源包括用于提供带电气溶胶的电喷雾离子化源，用于电喷雾离子化源的下游的大气压电离源，用于进一步电离所述带电气体，以及模式分离器或掩模，并且防止该部分暴露于大气压电离源。

6. 发明申请

US20050045833A1 Ion sampling for APPI mass spectrometry 有权
标题翻译：离子采样用于APPI质谱
公开(公告)号：US20050045833A1
公开(公告)日：2005-03-03
申请号：US10863967
申请日：2004-06-08
申请人： Steven Fischer , Darrell Gourley , Patricia Cormia , James Bertsch , Karl Hanold
发明人： Steven Fischer , Darrell Gourley , Patricia Cormia , James Bertsch , Karl Hanold
IPC分类号： G01N30/72 , H01J49/04 , H01J49/00
CPC分类号： G01N30/7253 , H01J27/24 , H01J49/0431 , H01J49/145 , H01J49/162
摘要： An atmospheric pressure ion source, e.g. for a mass spectrometer, that produces ions by atmospheric pressure photoionization (APPI). It includes a vaporizer, a photon source for photoionizing vapor molecules upon exit from the vaporizer, a passageway for transporting ions to, for example, a mass spectrometer system, and a means for directing the ions into the passageway. The center axis of the vaporizer and the center axis of the passageway form an angle that may be about 90 degrees. Included in the invention is a method for creating ions by atmospheric pressure photoionization along an axis and directing them into a passageway oriented at an angle to that axis.
摘要翻译：大气压离子源，例如用于通过大气压光电离（APPI）产生离子的质谱仪。它包括蒸发器，用于在蒸发器出口时使蒸汽分子光离子化的光子源，用于将离子输送到例如质谱仪系统的通道和用于将离子引导到通道中的装置。蒸发器的中心轴线和通道的中心轴线形成大约90度的角度。本发明中包括一种通过沿着轴的大气压力光离子化产生离子的方法，并将它们引导到与该轴成一定角度的通道中。

7. 发明申请

US20060243917A1 Apparatus and method for sensor control and feedback 有权
公开(公告)号：US20060243917A1
公开(公告)日：2006-11-02
申请号：US11471954
申请日：2006-06-21
申请人： Steven Fischer , Darrell Gourley , Glen Ingle , Timothy Joyce
发明人： Steven Fischer , Darrell Gourley , Glen Ingle , Timothy Joyce
IPC分类号： H01J27/24
CPC分类号： H01J49/04 , H01J49/10 , H01J49/107 , H01J49/165
摘要： The present invention relates to an apparatus and method for use with a mass spectrometry system. The invention provides an ion source, infrared emitter and sensor with closed control feedback loop coupled to the infrared emitter. Methods of control and heating using the apparatus of the present invention are also disclosed.

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