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1. 发明申请

US20060048321A1 Roller for mop 失效
标题翻译：拖把滚筒
公开(公告)号：US20060048321A1
公开(公告)日：2006-03-09
申请号：US10937527
申请日：2004-09-09
申请人： Christopher Boyer , Miroslav Vuckovic
发明人： Christopher Boyer , Miroslav Vuckovic
IPC分类号： A47L13/144
CPC分类号： A47L13/144
摘要： The cleaning implement includes a shaft having an operator end and a cleaning end, a mop head comprising a liquid-absorbent material and a wringing mechanism. The mop head and the wringing mechanism are movable relative to one another between at least a cleaning position and a plurality of wringing positions. The wringing mechanism includes a roller which compresses at least a portion of the liquid-absorbent material to thereby expel liquid therefrom. The plastic roller has a plurality of spaced ribs defining cavities therebetween. The ribs are complementally shaped and dimensioned to allow rolling contact relative to the liquid absorbent material as travel takes place between the cleaning position and a wringing position.
摘要翻译：清洁器具包括具有操作者端和清洁端的轴，包括吸液材料的拖把头和拧紧机构。拖把头和拧紧机构可在至少清洁位置和多个拧紧位置之间相对于彼此移动。拧紧机构包括压缩液体吸收材料的至少一部分从而从其排出液体的辊。塑料辊具有多个间隔开的肋，在它们之间形成空隙。这些肋互补形状和尺寸被设计成允许相对于液体吸收材料的滚动接触，因为在清洁位置和拧紧位置之间发生移动。

2. 发明申请

US20050155171A1 Mop 审中-公开
标题翻译：拖把
公开(公告)号：US20050155171A1
公开(公告)日：2005-07-21
申请号：US10760590
申请日：2004-01-20
申请人： Christopher Boyer , Terry Ashby
发明人： Christopher Boyer , Terry Ashby
IPC分类号： A47L13/146 , A47L13/258
CPC分类号： A47L13/258 , A47L13/146
摘要： The mop includes a handle, a pusher, a front cam, a rear cam, a mop element support and a mop element. The pusher may include a front arm and a rear arm with cam-engaging surfaces. The mop element support has a center portion;, a front portion and a rear portion. The front portion is attached to the center portion by a front living hinge and the rear portion is attached to the center portion by a rear living hinge. As the user moves the pusher relative to the shaft, the pusher would act upon the front cam and the rear cam. The front cam and the rear cams would begin to rotate and cause the rear portion of the mop element support to fold along the rear living hinge and the front portion of the mop element support to fold along the front living hinge. After the mop element has been squeezed, the user would then move the pusher in the opposite direction along the shaft. The pusher would engage the front and rear cams causing the front and rear portions of the mop element support to unfold along the living hinges.
摘要翻译：拖把包括手柄，推动器，前凸轮，后凸轮，拖把元件支架和拖把元件。推动器可以包括具有凸轮接合表面的前臂和后臂。拖把元件支撑件具有中心部分，前部和后部。前部通过前活动铰链附接到中心部分，后部通过后活动铰链附接到中心部分。当用户相对于轴移动推动器时，推动器将作用在前凸轮和后凸轮上。前凸轮和后凸轮将开始旋转，并且使得拖把元件支撑件的后部沿着后活动铰链折叠，并且拖把元件支撑件的前部部分沿着前活动铰链折叠。在拖把元件被挤压之后，使用者将沿着轴沿相反方向移动推动器。推动器将接合前凸轮和后凸轮，导致拖把元件支撑件的前部和后部沿着活动铰链展开。

3. 发明授权

US08088631B2 Lanthanide-doped NaYF4 nanocrystals, method of preparing and uses thereof 有权
标题翻译：掺杂镧系元素的NaYF4纳米晶体，其制备方法和用途
公开(公告)号：US08088631B2
公开(公告)日：2012-01-03
申请号：US12125201
申请日：2008-05-22
申请人： John A. Capobianco , John-Christopher Boyer , Louis A. Cuccia , Fiorenzo Vetrone
发明人： John A. Capobianco , John-Christopher Boyer , Louis A. Cuccia , Fiorenzo Vetrone
IPC分类号： G01N33/553
CPC分类号： C01F17/0031 , B82Y15/00 , B82Y30/00 , C01P2002/52 , C01P2002/72 , C01P2002/77 , C01P2002/84 , C01P2002/86 , C01P2004/04 , C01P2004/22 , C01P2004/52 , C01P2004/64 , C09D11/037 , G01N33/588
摘要： The present invention relates to a method of preparing lanthanide-doped NaYF4 nanocrystals, the method comprising: (A) providing a first solution comprising a non-coordinating solvent, a fatty acid coordinating ligand, sodium trifluoroacetate, yttrium trifluoroacetate, a first doping lanthanide trifluoroacetate and a second doping lanthanide trifluoroacetate, and a second solution comprising the non-coordinating solvent and the fatty acid coordinating ligand, the first and second solutions being substantially free of water and oxygen; (B) in an inert atmosphere, slowly adding the first solution heated at a temperature between about 100° C. and about 150° C. to the second solution heated at temperature between about 290° C. and about 330° C., thereby producing a reaction mixture containing the nanocrystals; and (C) recovering the nanocrystals from the reaction mixture. The invention also relates to lanthanide-doped uniformly shaped cubic NaYF4 nanocrystals having an average particle size of at most about 50 nm with a standard deviation of at most about 15%. Finally, the invention also relates to methods of (A) identifying or authenticating a product, (B) labelling an analyte, (C) detecting an analyte, and (D) producing a light source for the telecommunication industry using the above nanocrystals.
摘要翻译：本发明涉及一种制备镧系元素掺杂的NaYF4纳米晶体的方法，所述方法包括：（A）提供包含非配位溶剂，脂肪酸配位配体，三氟乙酸钠，三氟乙酸钇，第一掺杂镧系元素三氟乙酸盐和第二掺杂镧系元素三氟乙酸盐，以及包含所述非配位溶剂和所述脂肪酸配位配体的第二溶液，所述第一和第二溶液基本上不含水和氧; （B）在惰性气氛中，将在约100℃至约150℃的温度下加热的第一溶液缓慢加入到在约290℃至约330℃之间的温度下加热的第二溶液，由此产生含有纳米晶体的反应混合物; 和（C）从反应混合物中回收纳米晶体。本发明还涉及平均粒度为至多约50nm的标准偏差至多约15％的镧系元素掺杂均匀形状的立方晶NaYF4纳米晶体。最后，本发明还涉及（A）鉴定或认证产品的方法，（B）标记分析物，（C）检测分析物，和（D）使用上述纳米晶体生产电信工业的光源。

4. 发明申请

US20060211901A1 Process for the co-production of cumene and secondary butyl benzene 有权
公开(公告)号：US20060211901A1
公开(公告)日：2006-09-21
申请号：US11082263
申请日：2005-03-17
申请人： Christopher Boyer , Mitchell Loescher
发明人： Christopher Boyer , Mitchell Loescher
IPC分类号： C07C2/68
CPC分类号： C07C2/66 , C07C2529/70 , C07C2531/08 , Y02P20/127 , Y10S203/06 , C07C15/085 , C07C15/02
摘要： Cumene and secondary butyl benzene are produced simultaneously in a distillation column reactor by feeding propylene, butylene and benzene to the reactor. Unreacted benzene is removed as overheads and cumene and secondary butyl benzene are removed as products. The catalysts used are acid cation exchange resins, zeolites, particularly beta zeolite.

5. 发明申请

US20070155673A1 USE OF BVDU FOR INHIBITING THE GROWTH OF HYPERPROLIFERATIVE CELLS 审中-公开
标题翻译：使用BVDU抑制高增殖细胞的生长
公开(公告)号：US20070155673A1
公开(公告)日：2007-07-05
申请号：US11627341
申请日：2007-01-25
申请人： Christopher Boyer , David Lackey , H. Shepard
发明人： Christopher Boyer , David Lackey , H. Shepard
IPC分类号： A61K31/7072 , A61K31/7056 , A61K31/56 , A61K31/513
CPC分类号： A61K45/06 , A61K31/513 , A61K31/56 , A61K31/7056 , A61K31/7072 , G01N33/5011 , A61K2300/00
摘要： This invention provides methods for selectively killing a hyperproliferative cell by contacting the cell with the compound BVdU, its derivatives and pharmaceutically acceptable salts. Further provided by this invention is a method for treating a pathology in a subject characterized by pathological, hyperproliferative cells by administering to the subject an effective amount of the compound BVdU, its derivatives and pharmaceutically acceptable salts. The invention also provides a method for screening for potential therapeutic agents by contacting a neoplastic cell with the agent and with BVdU and performing an assay to detect inhibition of proliferation and cell killing. The invention also provides methods for selecting from among a patient population, patients that are likely to benefit from treatment with BVdU, by determining the level of endogenous, intracellular TK and TS. The invention also provides methods for sensitizing patients to the therapeutic effects of BVdU by treatment with substances that result in the increase in the levels of TK in hyperproliferative cells.
摘要翻译：本发明提供了通过使细胞与化合物BVdU及其衍生物和药学上可接受的盐接触来选择性杀死过度增殖细胞的方法。本发明进一步提供的是通过向受试者施用有效量的化合物BVdU及其衍生物和药学上可接受的盐来治疗特征在于病理性，过度增殖细胞的受试者的病理学的方法。本发明还提供了通过使肿瘤细胞与该药物和BVdU接触并进行测定以检测增殖和细胞杀伤的抑制来筛选潜在治疗剂的方法。本发明还提供了通过确定内源性，细胞内TK和TS的水平从患者群体中选择可能受益于BVdU治疗的患者的方法。本发明还提供了通过用导致过度增殖细胞中TK水平增加的物质进行处理使患者感觉BVdU治疗效果的方法。

6. 发明申请

US20060155154A1 Process for the selective hydrogenation of alkynes 审中-公开
标题翻译：炔烃选择性氢化方法
公开(公告)号：US20060155154A1
公开(公告)日：2006-07-13
申请号：US11031900
申请日：2005-01-07
申请人： J. Ryu , Christopher Boyer
发明人： J. Ryu , Christopher Boyer
IPC分类号： C07C5/03
CPC分类号： C10G45/34 , C07C7/167 , C10G49/002
摘要： A process for removal of acetylenic compounds from hydrocarbon streams in which a hydrocarbon feed having a target fraction which contains a first concentration of acetylenic compounds and olefins is contacted with a catalyst selective for the hydrogenation of acetylenic compounds in the presence of hydrogen and a solvent having a boiling point higher than the boiling point of the target fraction in a distillation reaction zone under conditions of temperature, pressure and hydrogen concentration favoring the hydrogenation of acetylenic compounds in which the target fraction is recovered as overheads having a second concentration of acetylenic compounds lower than said first concentration and the solvent is recovered as bottoms.
摘要翻译：一种从烃流中除去炔属化合物的方法，其中具有含有第一浓度的炔属化合物和烯烃的目标馏分的烃进料在氢气和溶剂存在下与选择性氢化炔属化合物的催化剂接触，在温度，压力和氢气浓度的条件下，在蒸馏反应区中沸点高于目标馏分的沸点，有利于其中回收目标馏分的炔属化合物的氢化，其中第二浓度的炔属化合物低于所述第一浓度和溶剂作为底部回收。

7. 发明申请

US20050256353A1 Selective hydrogenation of butadiene 有权
标题翻译：丁二烯的选择性氢化
公开(公告)号：US20050256353A1
公开(公告)日：2005-11-17
申请号：US10926207
申请日：2004-08-25
申请人： Christopher Boyer
发明人： Christopher Boyer
IPC分类号： C07C5/03 , C07C5/05 , C07C7/163
CPC分类号： C07C5/05 , C07C7/163 , C07C11/08 , C07C11/02
摘要： A process for the selective hydrogenation of dienes in mixed streams of olefin containing hydrocarbons, such as butadiene in a mixed C4 stream with minimum loss of monoolefins is disclosed wherein the reactor is operated at conditions which induce pulse flow. The pulse flow is induced in a downflow boiling point reactor by vaporization of a portion of the liquid feed at proper conditions.
摘要翻译：公开了一种在具有最小单烯烃损失的混合C 4+流中的含烯烃类烃如混合物流中二烯选择性氢化的方法，其中反应器在引起脉冲流动的条件下操作。在适当的条件下，通过一部分液体进料的蒸发，在下流沸点反应器中引发脉冲流。

8. 发明申请

US20050080035A1 Use of BVDU for inhibiting the growth of hyperproliferative cells 审中-公开
标题翻译：使用BVDU抑制过度增殖细胞的生长
公开(公告)号：US20050080035A1
公开(公告)日：2005-04-14
申请号：US10954797
申请日：2004-09-29
申请人： Christopher Boyer , David Lackey
发明人： Christopher Boyer , David Lackey
IPC分类号： A61K31/7072 , A61K45/06 , G01N33/50
CPC分类号： A61K45/06 , A61K31/513 , A61K31/56 , A61K31/7056 , A61K31/7072 , G01N33/5011 , A61K2300/00
摘要： This invention provides methods for selectively killing a hyperproliferative cell by contacting the cell with the compound BVdU, its derivatives and pharmaceutically acceptable salts. Further provided by this invention is a method for treating a pathology in a subject characterized by pathological, hyperproliferative cells by administering to the subject an effective amount of the compound BVdU, its derivatives and pharmaceutically acceptable salts. The invention also provides a method for screening for potential therapeutic agents by contacting a nonplastic cell with the agent and with BVdU and performing an assay to detect inhibition of proliferation and cell killing. The invention also provides methods for selecting from among a patient population, patients that are likely to benefit from treatment with BVdU, by determining die level of endogenous, intracellular TK and TS. The invention also provides methods for sensitizing patients to the therapeutic effects of BVdU by treatment with substances that result in the increase in the levels of TK in hyperproliferative cells.
摘要翻译：本发明提供了通过使细胞与化合物BVdU及其衍生物和药学上可接受的盐接触来选择性杀死过度增殖细胞的方法。本发明进一步提供的是通过向受试者施用有效量的化合物BVdU及其衍生物和药学上可接受的盐来治疗特征在于病理性，过度增殖细胞的受试者的病理学的方法。本发明还提供了通过使非肿瘤细胞与药物和BVdU接触并进行测定以检测增殖和细胞杀伤的抑制来筛选潜在治疗剂的方法。本发明还提供了通过确定内源性，细胞内TK和TS的死亡水平从患者群体中选择可能受益于BVdU治疗的患者的方法。本发明还提供了通过用导致过度增殖细胞中TK水平增加的物质进行处理使患者感觉BVdU治疗效果的方法。

9. 发明申请

US20090042314A1 LANTHANIDE-DOPED NAYF4 NANOCRYSTALS, METHOD OF PREPARING AND USES THEREOF 有权
标题翻译：纳米DADED NAYF4纳米晶体，其制备方法及其用途
公开(公告)号：US20090042314A1
公开(公告)日：2009-02-12
申请号：US12125201
申请日：2008-05-22
申请人： John A. Capobianco , John-Christopher Boyer , Louis A. Cuccia , Fiorenzo Vetrone
发明人： John A. Capobianco , John-Christopher Boyer , Louis A. Cuccia , Fiorenzo Vetrone
IPC分类号： G01N33/53
CPC分类号： C01F17/0031 , B82Y15/00 , B82Y30/00 , C01P2002/52 , C01P2002/72 , C01P2002/77 , C01P2002/84 , C01P2002/86 , C01P2004/04 , C01P2004/22 , C01P2004/52 , C01P2004/64 , C09D11/037 , G01N33/588
摘要： The present invention relates to a method of preparing lanthanide-doped NaYF4 nanocrystals, the method comprising: (A) providing a first solution comprising a non-coordinating solvent, a fatty acid coordinating ligand, sodium trifluoroacetate, yttrium trifluoroacetate, a first doping lanthanide trifluoroacetate and a second doping lanthanide trifluoroacetate, and a second solution comprising the non-coordinating solvent and the fatty acid coordinating ligand, the first and second solutions being substantially free of water and oxygen; (B) in an inert atmosphere, slowly adding the first solution heated at a temperature between about 100° C. and about 150° C. to the second solution heated at temperature between about 290° C. and about 330° C., thereby producing a reaction mixture containing the nanocrystals; and (C) recovering the nanocrystals from the reaction mixture. The invention also relates to lanthanide-doped uniformly shaped cubic NaYF4 nanocrystals having an average particle size of at most about 50 nm with a standard deviation of at most about 15%. Finally, the invention also relates to methods of (A) identifying or authenticating a product, (B) labelling an analyte, (C) detecting an analyte, and (D) producing a light source for the telecommunication industry using the above nanocrystals.
摘要翻译：本发明涉及一种制备镧系元素掺杂的NaYF4纳米晶体的方法，所述方法包括：（A）提供包含非配位溶剂，脂肪酸配位配体，三氟乙酸钠，三氟乙酸钇，第一掺杂镧系元素三氟乙酸盐和第二掺杂镧系元素三氟乙酸盐，以及包含所述非配位溶剂和所述脂肪酸配位配体的第二溶液，所述第一和第二溶液基本上不含水和氧; （B）在惰性气氛中，将在约100℃至约150℃的温度下加热的第一溶液缓慢加入到在约290℃至约330℃之间的温度下加热的第二溶液，由此产生含有纳米晶体的反应混合物; 和（C）从反应混合物中回收纳米晶体。本发明还涉及平均粒度为至多约50nm的标准偏差至多约15％的镧系元素掺杂均匀形状的立方晶NaYF4纳米晶体。最后，本发明还涉及（A）鉴定或认证产品的方法，（B）标记分析物，（C）检测分析物，和（D）使用上述纳米晶体生产电信工业的光源。

10. 发明申请

US20070289901A1 ENERGY EFFICIENT METHOD FOR EXOTHERMIC REACTIONS 有权
标题翻译：能量反应的能量有效方法
公开(公告)号：US20070289901A1
公开(公告)日：2007-12-20
申请号：US11845642
申请日：2007-08-27
申请人： Arvids Judzis , Abraham Gelbein , John Adams , Christopher Boyer
发明人： Arvids Judzis , Abraham Gelbein , John Adams , Christopher Boyer
IPC分类号： B01D3/00
CPC分类号： B01D3/009 , B01J19/0033 , B01J2219/00006 , Y10S203/08 , Y10S585/914
摘要： An energy efficient process scheme for a highly exothermic reaction-distillation system in which the reactor is external to the distillation column and the feed to the reactor is a mixture of at least one liquid product stream from the distillation column with or without other liquid/vapor reactants. The reactor is operated under adiabatic and boiling point conditions and at a pressure that results in vaporizing a portion of the liquid flow through the reactor due to the heat of reaction. Under these conditions, reaction temperature is controlled by reactor pressure. The pressure (and hence the temperature) is maintained at a sufficiently high level such that the reactor effluent can be efficiently used to provide reboil heat for the distillation column.
摘要翻译：用于高放热反应 - 蒸馏系统的能量效率方法，其中反应器在蒸馏塔外部和反应器的进料是来自蒸馏塔的至少一种液体产物流与有或没有其它液体/蒸气的混合物反应物。反应器在绝热和沸点条件下运行，并且在由于反应热导致部分液体流过反应器的压力下运行。在这些条件下，反应温度由反应器压力控制。压力（因此温度）保持在足够高的水平，使得反应器流出物可以有效地用于为蒸馏塔提供再沸腾热。

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