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1. 发明授权

US09261496B2 Device for high throughput investigations of multi-cellular interactions 有权
标题翻译：用于多细胞相互作用的高通量调查的装置
公开(公告)号：US09261496B2
公开(公告)日：2016-02-16
申请号：US13876293
申请日：2011-09-29
申请人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
发明人： Roger Dale Kamm , Haruhiko Harry Asada , Waleed Ahmed Farahat , Ioannis K. Zervantonakis , Levi B. Wood , Chandrasekhar Kothapalli , Seok Chung , Jeffrey D. Macklis , Suzanne Tharin , Johanna Varner , Young Kum Park , Kwang Ho Lee , Le Thanh Tu Nguyen , Choong Kim
IPC分类号： C12M1/34 , C12M3/00 , G01N33/50 , B01L3/00 , C12M3/06 , C12M1/00 , C12M1/12
CPC分类号： G01N33/5008 , B01L3/502753 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2300/0681 , B01L2300/069 , B01L2300/0816 , C12M23/16 , C12M23/22 , C12M25/14 , C12M29/04 , G01N33/5011 , G01N33/5029 , G01N33/5058 , G01N33/5064
摘要： Provided herein are microfluidic devices that can be used as a 3D bioassay, e.g., for drug screening, personalized medicine, tissue engineering, wound healing, and other applications. The device has a series of channels {e.g., small fluid channels) in a small polymer block wherein one or more of the channels can be filled with a biologically relevant gel, such as collagen, which is held in place by posts. As shown herein, when the device is plated with cells such as endothelial cells, new blood vessels grow in the gel, which is thick enough for the cells to grow in three dimensions. Other channels, e.g., fluid channels, allow drugs or biological material to be exposed to the 3D cell growth. Cells, such as endothelial cells, can be cultured and observed as they grow on the surface of a 3D gel scaffold, where e.g., rates of angiogenesis can be measured, as well as intervascularization and extravascularization of cancerous cells.
摘要翻译：本文提供的微流体装置可用作3D生物测定，例如用于药物筛选，个性化医学，组织工程，伤口愈合和其它应用。该装置在小聚合物嵌段中具有一系列通道（例如，小的流体通道），其中一个或多个通道可以填充生物相关凝胶，例如通过柱保持在适当位置的胶原。如本文所示，当该装置镀有诸如内皮细胞的细胞时，新的血管在凝胶中生长，其足够厚以使细胞在三维中生长。其他通道，例如流体通道，允许药物或生物材料暴露于3D细胞生长。可以在3D凝胶支架的表面上生长细胞，例如内皮细胞，并且观察细胞，其中例如可以测量血管发生的速率，以及癌细胞的血管间血管形成和血管外再造。

2. 发明授权

US09130119B2 Non-polar and semi-polar light emitting devices 有权
标题翻译：非极性和半极性发光器件
公开(公告)号：US09130119B2
公开(公告)日：2015-09-08
申请号：US12001227
申请日：2007-12-11
申请人： Steven P. DenBaars , Mathew C. Schmidt , Kwang Choong Kim , James S. Speck , Shuji Nakamura
发明人： Steven P. DenBaars , Mathew C. Schmidt , Kwang Choong Kim , James S. Speck , Shuji Nakamura
IPC分类号： H01L33/00 , H01L33/32 , B82Y20/00 , H01L33/06 , H01L33/16 , H01L33/22 , H01S5/22 , H01S5/223 , H01S5/34 , H01S5/343
CPC分类号： H01L33/32 , B82Y20/00 , H01L33/06 , H01L33/16 , H01L33/22 , H01S5/2201 , H01S5/2231 , H01S5/3404 , H01S5/34333
摘要： An (Al, Ga, In)N light emitting device, such as a light emitting diode (LED), in which high light generation efficiency is realized by fabricating the device on non-polar or semi-polar III-Nitride crystal geometries. Because non-polar and semi-polar emitting devices have significantly lower piezoelectric effects than c-plane emitting devices, higher efficiency emitting devices at higher current densities can be realized.
摘要翻译：一种（Al，Ga，In）N发光器件，例如发光二极管（LED），其中通过以非极性或半极性III氮化物晶体几何形状制造器件来实现高发光效率。因为非极性和半极性发射器件具有比c面发射器件显着更低的压电效应，所以可以实现在更高电流密度下的更高效率的发射器件。

3. 发明授权

US08956896B2 Metalorganic chemical vapor deposition (MOCVD) growth of high performance non-polar III-nitride optical devices 有权
标题翻译：金属有机化学气相沉积（MOCVD）生长的高性能非极性III族氮化物光学器件
公开(公告)号：US08956896B2
公开(公告)日：2015-02-17
申请号：US13440087
申请日：2012-04-05
申请人： Mathew C. Schmidt , Kwang Choong Kim , Hitoshi Sato , Steven P. DenBaars , James S. Speck , Shuji Nakamura
发明人： Mathew C. Schmidt , Kwang Choong Kim , Hitoshi Sato , Steven P. DenBaars , James S. Speck , Shuji Nakamura
IPC分类号： H01L21/36 , H01L33/00 , H01L21/00 , B82Y20/00 , H01L21/02 , H01S5/343
CPC分类号： H01L33/0075 , B82Y20/00 , H01L21/0237 , H01L21/02389 , H01L21/02458 , H01L21/02507 , H01L21/0254 , H01S5/34333 , H01S2304/04
摘要： A method of device growth and p-contact processing that produces improved performance for non-polar III-nitride light emitting diodes and laser diodes. Key components using a low defect density substrate or template, thick quantum wells, a low temperature p-type III-nitride growth technique, and a transparent conducting oxide for the electrodes.
摘要翻译：一种器件生长和p接触处理的方法，其产生非极性III族氮化物发光二极管和激光二极管的改善的性能。使用低缺陷密度衬底或模板的关键组件，厚量子阱，低温p型III族氮化物生长技术和用于电极的透明导电氧化物。

4. 发明授权

US08436389B2 Light emitting device having a plurality of non-polar light emitting cells and a method of fabricating the same 有权
标题翻译：具有多个非极性发光单元的发光器件及其制造方法
公开(公告)号：US08436389B2
公开(公告)日：2013-05-07
申请号：US13482851
申请日：2012-05-29
申请人： Kwang Choong Kim , Won Cheol Seo , Dae Won Kim , Dae Sung Kal , Kyung Hee Ye
发明人： Kwang Choong Kim , Won Cheol Seo , Dae Won Kim , Dae Sung Kal , Kyung Hee Ye
IPC分类号： H01L33/00
CPC分类号： H01L33/32 , H01L27/153 , H01L33/0079 , H01L33/18 , H01L33/20 , H01L33/44 , H01L33/62 , H01L2924/0002 , H01L2924/00
摘要： The present invention relates to a light emitting device having a plurality of non-polar light emitting cells and a method of fabricating the same. Nitride semiconductor layers are disposed on a Gallium Nitride substrate having an upper surface. The upper surface is a non-polar or semi-polar crystal and forms an intersection angle with respect to a c-plane. The nitride semiconductor layers may be patterned to form light emitting cells separated from one another. When patterning the light emitting cells, the substrate may be partially removed in separation regions between the light emitting cells to form recess regions. The recess regions are filled with an insulating layer, and the substrate is at least partially removed by using the insulating layer.
摘要翻译：本发明涉及具有多个非极性发光单元的发光器件及其制造方法。氮化物半导体层设置在具有上表面的氮化镓衬底上。上表面是非极性或半极性的晶体，相对于c面形成交叉角。氮化物半导体层可以被图案化以形成彼此分离的发光单元。当图案化发光单元时，可以在发光单元之间的分离区域中部分地去除衬底，以形成凹陷区域。凹部区域填充有绝缘层，并且通过使用绝缘层至少部分地去除衬底。

5. 发明申请

US20120256158A1 Al(x)Ga(1-x)N-CLADDING-FREE NONPOLAR III-NITRIDE BASED LASER DIODES AND LIGHT EMITTING DIODES 审中-公开
标题翻译： Al（x）Ga（1-x）N型无铅非极性III型氮化物激光二极管和发光二极管
公开(公告)号：US20120256158A1
公开(公告)日：2012-10-11
申请号：US13495231
申请日：2012-06-13
申请人： Daniel F. Feezell , Mathew C. Schmidt , Kwang Choong Kim , Robert M. Farrell , Daniel A. Cohen , James S. Speck , Steven P. DenBaars , Shuji Nakamura
发明人： Daniel F. Feezell , Mathew C. Schmidt , Kwang Choong Kim , Robert M. Farrell , Daniel A. Cohen , James S. Speck , Steven P. DenBaars , Shuji Nakamura
IPC分类号： H01L33/04
CPC分类号： H01L33/32 , B82Y20/00 , H01L33/02 , H01L33/06 , H01L33/16 , H01S5/3211 , H01S5/34333
摘要： A method for fabricating AlxGa1-xN-cladding-free nonpolar III-nitride based laser diodes or light emitting diodes. Due to the absence of polarization fields in the nonpolar crystal planes, these nonpolar devices have thick quantum wells that function as an optical waveguide to effectively confine the optical mode to the active region and eliminate the need for Al-containing waveguide cladding layers.
摘要翻译：一种制造Al x Ga 1-x N不包覆非极性III族氮化物基激光二极管或发光二极管的方法。由于在非极性晶面中没有极化场，这些非极性器件具有用作光波导的厚量子阱，以有效地将光学模式限制在有源区，并且不需要含Al波导覆层。

6. 发明授权

US08273311B2 Apparatus and method for separating biological particles using difference between gravity and magnetic force 有权
标题翻译：使用重力和磁力之间的差异分离生物颗粒的装置和方法
公开(公告)号：US08273311B2
公开(公告)日：2012-09-25
申请号：US12160242
申请日：2007-01-11
申请人： Kang Sun Lee , Ji Yoon Kang , Sung Shin Ryu , In Hye Lee , Choong Kim , Su Kyoung Chae , Jin Woo Lee
发明人： Kang Sun Lee , Ji Yoon Kang , Sung Shin Ryu , In Hye Lee , Choong Kim , Su Kyoung Chae , Jin Woo Lee
IPC分类号： B01D21/00
CPC分类号： B03C1/288 , B03C1/30
摘要： Disclosed is an apparatus and method for injecting liquid-drops of particle mixture liquid including a mixture of biological particles, affecting magnetic field, and having only positive particles, which are combined with magnetic responsive material, separated by magnetic force, and having negative particles, which are not combined with magnetic responsive material, precipitated by gravity.
摘要翻译：本发明涉及一种装置和方法，用于将包括影响磁场的生物颗粒的混合物的粒子混合液体的液滴注入，并且仅具有正磁性颗粒，其与通过磁力分离并具有负性颗粒的磁响应材料组合，其不与磁响应材料结合，由重力沉淀。

7. 发明申请

US20120199809A1 METALORGANIC CHEMICAL VAPOR DEPOSITION (MOCVD) GROWTH OF HIGH PERFORMANCE NON-POLAR III-NITRIDE OPTICAL DEVICES 有权
标题翻译：金属化学气相沉积（MOCVD）高性能非极性III-NITRIDE光学器件的生长
公开(公告)号：US20120199809A1
公开(公告)日：2012-08-09
申请号：US13440087
申请日：2012-04-05
申请人： Mathew C. Schmidt , Kwang Choong Kim , Hitoshi Sato , Steven P. DenBaars , James S. Speck , Shuji Nakamura
发明人： Mathew C. Schmidt , Kwang Choong Kim , Hitoshi Sato , Steven P. DenBaars , James S. Speck , Shuji Nakamura
IPC分类号： H01L33/04
CPC分类号： H01L33/0075 , B82Y20/00 , H01L21/0237 , H01L21/02389 , H01L21/02458 , H01L21/02507 , H01L21/0254 , H01S5/34333 , H01S2304/04
摘要： A method of device growth and p-contact processing that produces improved performance for non-polar III-nitride light emitting diodes and laser diodes. Key components using a low defect density substrate or template, thick quantum wells, a low temperature p-type III-nitride growth technique, and a transparent conducting oxide for the electrodes.
摘要翻译：一种器件生长和p接触处理的方法，其产生非极性III族氮化物发光二极管和激光二极管的改善的性能。使用低缺陷密度衬底或模板的关键组件，厚量子阱，低温p型III族氮化物生长技术和用于电极的透明导电氧化物。

8. 发明授权

US07819039B2 Steering apparatus 有权
标题翻译：转向装置
公开(公告)号：US07819039B2
公开(公告)日：2010-10-26
申请号：US12473518
申请日：2009-05-28
申请人： Young Choong Kim
发明人： Young Choong Kim
IPC分类号： B62D1/04
CPC分类号： B63H25/10 , B63H2025/022 , Y10T74/20834
摘要： Disclosed herein is a steering apparatus of a small ship such as a motorboat, which prevents abrasion and noise caused by a gap between a rotary cover and a rotary plate and maximizes steering handle rotation prevention effect. The steering apparatus includes a cylindrical fixed frame; the rotary plate rotatably set inside the fixed frame; a plurality of mounts arranged on the rotary plate and having rolling elements and elastic elements mounted thereon; the elastic elements mounted on the mounts and applying elasticity to the rolling elements to press the rolling elements against the inner face of the fixed frame; the rotary cover including a movable part having movable pieces capable of pressing the rolling elements when a steering shaft is operated and covering the top of the rotary plate to prevent the rolling elements and the elastic elements from being separated from the mounts; the steering shaft penetrating the fixed frame, the rotary plate and the rotary cover; and elastic pads respectively attached to portions of the movable pieces, which come into contact with the rolling elements, to eliminate a gap between each movable piece and each rolling element.
摘要翻译：这里公开了一种诸如摩托艇的小船的转向装置，其防止由旋转盖和旋转板之间的间隙引起的磨损和噪音，并且使转向手柄旋转防止效果最大化。转向装置包括：圆柱形固定框架; 旋转板可旋转地设置在固定框架内; 多个安装件，布置在旋转板上并具有安装在其上的滚动元件和弹性元件; 所述弹性元件安装在所述安装件上并且对所述滚动元件施加弹性以将所述滚动元件压靠在所述固定框架的内表面上; 所述旋转盖包括具有可动部件的可动部件，所述可移动部件能够在转向轴操作时能够按压所述滚动元件并且覆盖所述旋转板的顶部以防止所述滚动元件和所述弹性元件与所述支架分离; 转向轴穿过固定框架，旋转板和旋转盖; 以及分别附接到与滚动元件接触的可动件的部分的弹性垫，以消除每个可动件与每个滚动元件之间的间隙。

9. 发明申请

US20100163900A1 LIGHT EMITTING DEVICE HAVING PLURALITY OF NON-POLAR LIGHT EMITTING CELLS AND METHOD OF FABRICATING THE SAME 有权
标题翻译：具有非极性发光电池的多重性的发光装置及其制造方法
公开(公告)号：US20100163900A1
公开(公告)日：2010-07-01
申请号：US12624011
申请日：2009-11-23
申请人： Won Cheol SEO , Kwang Choong KIM , Kyung Hee YE
发明人： Won Cheol SEO , Kwang Choong KIM , Kyung Hee YE
IPC分类号： H01L33/00 , H01L21/30
CPC分类号： H01L33/007 , H01L27/156
摘要： Disclosed are a light emitting device having a plurality of non-polar light emitting cells and a method of fabricating the same. This method comprises preparing a first substrate of sapphire or silicon carbide having an upper surface with an r-plane, an a-plane or an m-plane. The first substrate has stripe-shaped anti-growth patterns on the upper surface thereof, and recess regions having sidewalls of a c-plane between the anti-growth patterns. Nitride semiconductor layers are grown on the substrate having the recess regions, and the nitride semiconductor layers are patterned to form the light emitting cells separated from one another. Accordingly, there is provided a light emitting device having non-polar light emitting cells with excellent crystal quality.
摘要翻译：公开了具有多个非极性发光单元的发光器件及其制造方法。该方法包括制备具有上表面的蓝宝石或碳化硅的第一衬底，其具有r面，a面或m面。第一衬底在其上表面上具有条状的抗生长图案，以及在抗生长图案之间具有c面侧壁的凹陷区域。在具有凹陷区域的衬底上生长氮化物半导体层，并且将氮化物半导体层图案化以形成彼此分离的发光元件。因此，提供了具有优异的晶体质量的非极性发光单元的发光器件。

10. 发明申请

US20090242870A1 LIGHT EMITTING DEVICE AND METHOD FOR MANUFACTURING THE SAME 审中-公开
公开(公告)号：US20090242870A1
公开(公告)日：2009-10-01
申请号：US12193588
申请日：2008-08-18
申请人： Gyu Beom KIM , Sang Joon LEE , Chang Suk HAN , Kwang Choong KIM
发明人： Gyu Beom KIM , Sang Joon LEE , Chang Suk HAN , Kwang Choong KIM
IPC分类号： H01L33/00
CPC分类号： H01L33/04 , B82Y20/00 , H01L33/32 , H01S5/3063 , H01S5/3216 , H01S5/34333 , H01S2304/04
摘要： Disclosed herein is a light emitting device. The light emitting device includes an n-type nitride semiconductor layer; an active layer on the n-type semiconductor layer, an AlN/GaN layer of a super lattice structure formed by alternately growing an AlN layer and a GaN layer on the active layer, and a p-type nitride semiconductor layer on the AlN/GaN layer of the super lattice structure. At least one of the AlN layer and the GaN layer is doped with a p-type dopant. A method for manufacturing the light emitting device is also provided.

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