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    • 1. 发明授权
    • Electromagnetic radiation delivery apparatus
    • 电磁辐射输送装置
    • US08623002B2
    • 2014-01-07
    • US10566199
    • 2004-07-20
    • Michiel Errit RoersmaBernardus Leonardus Gerardus Bakker
    • Michiel Errit RoersmaBernardus Leonardus Gerardus Bakker
    • A61B18/18
    • A61N5/0616A61B18/20A61B18/203A61B2018/00452A61B2018/00636A61B2090/064
    • The present invention relates to a device for administering electromagnetic radiation to human tissue, in particular light to skin. The device comprises a treatment head with a recess (10) in which the light is emitted and in which the air pressure may be decreased by a pump (11). The device also comprises a pressure gauge (8) for measuring the pressure in the recess (10). Above a certain threshold value the device will not function, because this indicates an incorrect positioning of the device on the skin, which might cause harm to persons. By providing the pressure gauge (8), an operator may determine whether the positioning of the treatment head is correct. The device is advantageously automated in that the pressure gauge (8) is connected to control means (5) for controlling the source (3) of radiation.
    • 本发明涉及一种用于向人体组织,特别是对皮肤照射电磁辐射的装置。 该装置包括具有凹部(10)的处理头,其中发射光,并且其中空气压力可以通过泵(11)减小。 该装置还包括用于测量凹部(10)中的压力的​​压力计(8)。 超过某个阈值时,设备将不起作用,因为这表示设备在皮肤上的定位不正确,可能会对人造成伤害。 通过提供压力计(8),操作者可以确定治疗头的定位是否正确。 该装置有利地是自动化的,因为压力计(8)连接到用于控制辐射源(3)的控制装置(5)。
    • 2. 发明授权
    • Calibration of optical analysis making use of multivariate optical elements
    • 使用多变量光学元件的光学分析校准
    • US07899636B2
    • 2011-03-01
    • US11721368
    • 2005-12-12
    • Bernardus Leonardus Gerardus Bakker
    • Bernardus Leonardus Gerardus Bakker
    • G06F19/00G01J3/00
    • G01N21/65G01J3/28G01N21/276G01N2021/1748G01N2201/1293
    • A method of calibrating an optical analysis system uses multivariate optical signal analysis. The method includes determining a parameter of a reference sample, and comparing the actually determined parameter with a reference parameter that represents a precise and real property of the reference sample. Based on the comparison, a calibration value is determined that is applicable to perform a calibration of the optical analysis system with respect to at least one compound or analyte of the reference sample. Parameters and reference parameters of a reference sample may refer to a concentration of an analyte dissolved in the sample, or to spectroscopic background signals that have to be taken into account when performing a spectral analysis based on optical signals obtained from the reference sample. Analyte-specific reference data is stored in a calibration unit of the optical analysis system and allows a high degree of automation of the calibration process.
    • 校准光学分析系统的方法使用多变量光信号分析。 该方法包括确定参考样本的参数,以及将实际确定的参数与表示参考样本的精确和不动性的参考参数进行比较。 基于比较,确定适用于相对于参考样品的至少一种化合物或分析物执行光学分析系统的校准的校准值。 参考样品的参数和参考参数可以指溶解在样品中的分析物的浓度,或者基于从参考样品获得的光学信号进行光谱分析时必须考虑的光谱背景信号。 分析物特异性参考数据存储在光学分析系统的校准单元中,并允许校准过程的高度自动化。
    • 4. 发明授权
    • Device for treating human skin by means of radiation
    • 用于通过辐射处理人体皮肤的装置
    • US07252628B2
    • 2007-08-07
    • US10538620
    • 2003-11-18
    • Robbert Adrianus Maria Van HalBernardus Leonardus Gerardus BakkerMichiel Errit RoersmaPeter Bjerring
    • Robbert Adrianus Maria Van HalBernardus Leonardus Gerardus BakkerMichiel Errit RoersmaPeter Bjerring
    • A61N5/00
    • A61B18/203A61B2018/00011A61B2018/00452A61B2018/00476A61B2018/1807
    • The invention relates to a device (1) for treating human skin by means of radiation. The device has a housing (5) with a radiation exit opening (13), a radiation source (9) which is accommodated in the housing, and a radiation path (15) between the radiation source and the radiation exit opening. A radiation filter (17) is provided in the radiation path. According to the invention the radiation filter (17) comprises water (23) which is in solid state at least during an initial phase of operation of the device (1). The water in solid state has an optical transmission spectrum which corresponds to the optical transmission spectrum of water in liquid state as present in the skin. As a result the water in solid state acts as an ideal filter for the IR light and near IR light, which would otherwise be absorbed by the water in the skin and cause unwanted heating of the skin. An additional advantage of the water in solid state is its relatively high heat absorbing capacity and its ability to cool the skin in case of direct thermal contact with the skin. In a particular embodiment the device (1) is an epilator for the removal of hairs from the human skin, the radiation source (9) being a flash lamp which generates light pulses having a high energy density and a broad optical spectrum.
    • 本发明涉及一种用于通过辐射处理人体皮肤的装置(1)。 该装置具有壳体(5),其具有辐射出口(13),容纳在壳体中的辐射源(9)和辐射源与辐射出口之间的辐射路径(15)。 辐射过滤器(17)设置在辐射路径中。 根据本发明,辐射过滤器(17)包括至少在设备(1)的初始操作阶段期间处于固态的水(23)。 固态的水具有对应于存在于皮肤中的处于液态的水的光透射光谱的光透射光谱。 因此,固态的水作为IR光和近红外光的理想过滤器,否则会被皮肤中的水吸收并引起皮肤不必要的加热。 固体水中的另一个优点是其相对较高的吸热能力以及在与皮肤直接热接触的情况下冷却皮肤的能力。 在特定实施例中,装置(1)是用于从人体皮肤去除毛发的脱毛器,所述辐射源(9)是产生具有高能量密度和宽光谱的光脉冲的闪光灯。
    • 5. 发明申请
    • CALIBRATION OF OPTICAL ANALYSIS MAKING USE OF MULTIVARIATE OPTICAL ELEMENTS
    • 光学分析的校准制造多光学元件的使用
    • US20100042348A1
    • 2010-02-18
    • US11721368
    • 2005-12-12
    • Bernardus Leonardus Gerardus BAKKER
    • Bernardus Leonardus Gerardus BAKKER
    • G06F19/00G01J1/10G01J3/00
    • G01N21/65G01J3/28G01N21/276G01N2021/1748G01N2201/1293
    • The invention provides a method of calibrating an optical analysis system that makes use of multivariate optical signal analysis allowing to realize cost-efficient and robust implementation of a spectral analysis of an optical signal. The calibration method makes use of determining a parameter of a reference sample by means of the optical analysis system and comparing the actually determined parameter with a reference parameter that represents a precise and real property of the reference sample. Based on this comparison a calibration value can be determined that is applicable to perform a calibration of the optical analysis system with respect to at least one compound or analyte of the reference sample. Parameters and reference parameters of a reference sample may refer to a concentration of an analyte dissolved in the sample, or to spectroscopic background signals that have to be taken into account when performing a spectral analysis based on optical signals obtained from the reference sample. Various different reference samples providing a reference with respect to different acquisition conditions and different analyte or compound concentrations can be universally used. Analyte-specific reference data is preferably stored in a calibration unit of the optical analysis system and allows a high degree of automation of the calibration process.
    • 本发明提供了一种校准光学分析系统的方法,其利用多变量光信号分析,从而实现光信号的光谱分析的成本有效且鲁棒的实现。 校准方法利用通过光学分析系统确定参考样本的参数,并将实际确定的参数与表示参考样本的精确和不变性的参考参数进行比较。 基于该比较,可以确定适用于相对于参考样品的至少一种化合物或分析物执行光学分析系统的校准的校准值。 参考样品的参数和参考参数可以指溶解在样品中的分析物的浓度,或者基于从参考样品获得的光学信号进行光谱分析时必须考虑的光谱背景信号。 可以普遍使用提供关于不同采集条件和不同分析物或化合物浓度的参考的各种不同参考样品。 分析物特异性参考数据优选地存储在光学分析系统的校准单元中,并允许校准过程的高度自动化。
    • 7. 发明授权
    • Device for treating human skin by means of radiation
    • 用于通过辐射处理人体皮肤的装置
    • US07517344B2
    • 2009-04-14
    • US10536242
    • 2003-10-31
    • Robbert Adrianus Maria Van HalBernardus Leonardus Gerardus BakkerPaul Anton Josef Ackermans
    • Robbert Adrianus Maria Van HalBernardus Leonardus Gerardus BakkerPaul Anton Josef Ackermans
    • A61B18/18
    • A61B18/203A61B2018/00005A61B2018/00452A61B2018/1807
    • The invention relates to a device (1) for treating human skin by means of radiation. The device comprises a housing (3) with a radiation exit opening (13). A radiation source (9) is accommodated in the housing. Radiation generated by the radiation source propagates from the radiation source towards the radiation exit opening via a radiation path (15) comprising a radiation filter having a predetermined transmission spectrum. According to the invention the radiation filter comprises a reflecting surface (23) via which the radiation propagating along the radiation path (15) is reflected. The reflecting surface has a coating which provides the reflecting surface with a reflection spectrum substantially matching the predetermined transmission spectrum. An advantage is that the reflection surface can be optimally and uniformly cooled, so that the heat generated as a result of the absorption of part of the radiation by the radiation filter can be effectively transmitted to a cooling system (25) of the device (1). In a particular embodiment the device (1) is an epilator for removing hairs from the human skin and the radiation source (9) is a flash lamp. The radiation path (15) is enclosed by a channel (17) having a bend (19) and having an inner wall (21) on which the reflecting surface (23) is provided.
    • 本发明涉及一种用于通过辐射处理人体皮肤的装置(1)。 该装置包括具有辐射出口(13)的壳体(3)。 辐射源(9)容纳在壳体中。 由辐射源产生的辐射经由包括具有预定透射光谱的辐射滤光片的辐射路径(15)从辐射源向辐射出口开口传播。 根据本发明,辐射过滤器包括反射表面(23),沿着辐射路径(15)传播的辐射被反射。 反射面具有使反射面具有基本上与预定透射光谱相一致的反射光谱的涂层。 优点在于反射面可以被最佳和均匀地冷却,使得由辐射过滤器吸收一部分辐射而产生的热能被有效地传递到装置(1)的冷却系统(25) )。 在特定实施例中,装置(1)是用于从人体皮肤去除头发的脱毛器,并且辐射源(9)是闪光灯。 辐射路径(15)由具有弯曲部(19)的通道(17)包围,并具有设置有反射面(23)的内壁(21)。