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1. 发明授权

US08543208B2 Systems and methods for interacting with an implantable medical device 有权
公开(公告)号：US08543208B2
公开(公告)日：2013-09-24
申请号：US12554959
申请日：2009-09-07
申请人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R. M. Upton
发明人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R. M. Upton
IPC分类号： A61N1/00
CPC分类号： A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
摘要： An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

2. 发明授权

US08369940B2 Devices and methods for monitoring physiological information relating to sleep with an implantable device 有权
标题翻译：用于通过可植入装置监测与睡眠相关的生理信息的装置和方法
公开(公告)号：US08369940B2
公开(公告)日：2013-02-05
申请号：US13274037
申请日：2011-10-14
申请人： Felice Sun , Benjamin D Pless , Barbara Gibb
发明人： Felice Sun , Benjamin D Pless , Barbara Gibb
IPC分类号： A61B5/048
CPC分类号： A61B5/4812 , A61B5/01 , A61B5/0205 , A61B5/02438 , A61B5/026 , A61B5/04012 , A61B5/0452 , A61B5/0476 , A61B5/0478 , A61B5/11 , A61B5/1118 , A61B5/14551 , A61B5/4815 , A61B5/686 , A61N1/36082 , A61N1/36135 , G06F19/00
摘要： Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.
摘要翻译：这里描述的是用于监测与睡眠相关的生理信息的可植入装置和方法。可植入装置通常设计成包括用于感测生理信息的至少一个传感器，用于使用低计算能力处理生理信息以检测睡眠阶段的处理器以及电池。然后可以使用检测到的睡眠阶段信息来指示睡眠质量，识别或监测医疗状况或指导治疗。

3. 发明授权

US07136695B2 Patient-specific template development for neurological event detection 有权
公开(公告)号：US07136695B2
公开(公告)日：2006-11-14
申请号：US09977052
申请日：2001-10-12
申请人： Benjamin D. Pless , Thomas K. Tcheng , Eyad Kishawi , Barbara Gibb , Javier Echauz , Rosana Esteller
发明人： Benjamin D. Pless , Thomas K. Tcheng , Eyad Kishawi , Barbara Gibb , Javier Echauz , Rosana Esteller
IPC分类号： A61B5/0476 , A61N1/18
CPC分类号： G06F19/3418 , A61B5/0476 , A61B5/4094 , A61B5/7217 , G06F19/00
摘要： An epileptiform activity patient-specific template creation system permits a user to efficiently develop an optimized set of patient-specific parameters for epileptiform activity detection algorithms. The epileptiform activity patient template creation system is primarily directed for use with an implantable neurostimulator system having EEG storage capability, in conjunction with a computer software program operating within a computer workstation having a processor, disk storage and input/output facilities for storing, processing and displaying patient EEG signals. The implantable neurostimulator is operative to store records of EEG data when neurological events are detected, when it receives external commands to record, or at preset or random times. The computer workstation operates on stored and uploaded records of EEG data to derive the patient-specific templates.

4. 发明申请

US20060212092A1 Systems and methods for interacting with an implantable medical device 有权
公开(公告)号：US20060212092A1
公开(公告)日：2006-09-21
申请号：US11436190
申请日：2006-05-16
申请人： Benjamin Pless , David Fischell , Barbara Gibb , Lisa Guzzo , Adrian Upton
发明人： Benjamin Pless , David Fischell , Barbara Gibb , Lisa Guzzo , Adrian Upton
IPC分类号： A61N1/36
CPC分类号： A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
摘要： An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.

5. 发明申请

US20130073003A1 Devices, Methods, and Systems for Harvesting Energy in the Body 审中-公开
标题翻译：用于在体内收获能量的装置，方法和系统
公开(公告)号：US20130073003A1
公开(公告)日：2013-03-21
申请号：US13674729
申请日：2012-11-12
申请人： Benjamin David Pless , Carl Lance Boling , Barbara Gibb , Adolf van der Heide , Brett M. Wingeier
发明人： Benjamin David Pless , Carl Lance Boling , Barbara Gibb , Adolf van der Heide , Brett M. Wingeier
IPC分类号： A61N1/378
CPC分类号： A61N1/3785 , H02N2/18 , H02N11/002
摘要： In some embodiments, the power generator for converting mechanical energy to electrical energy may include a compressible element adapted and configured to be placed in an environment having a variable compressive force such as varying ambient pressures. The compressible element may be compressed by a force applied by the variable pressure to the compressible element. The power generator may further include a transducer that may be coupled to the compressible element and that may convert mechanical energy from the compression of the compressible element to electrical energy. In some embodiments, the power generator may be adapted to be an implantable power generator for converting mechanical energy from a patient to electrical energy, such that the compressible element adapted and configured to be placed between two adjacent tissue layers of the patient and to be compressed by a force applied from the two adjacent tissue layers to the compressible element.
摘要翻译：在一些实施例中，用于将机械能转换成电能的发电机可以包括可压缩元件，该可压缩元件适于并被配置为放置在具有可变压缩力（例如变化的环境压力）的环境中。可压缩元件可以通过由可变压力施加到可压缩元件的力而被压缩。发电机还可以包括可耦合到可压缩元件并且可将机械能从可压缩元件的压缩转换为电能的换能器。在一些实施例中，发电机可以适于作为可植入的发电机，用于将来自患者的机械能转换成电能，使得可压缩元件适于并被配置成放置在患者的两个相邻组织层之间并被压缩通过从两个相邻组织层施加到可压缩元件的力。

6. 发明申请

US20110112381A1 Devices and methods for monitoring physiological information relating to sleep with an implantable device 有权
公开(公告)号：US20110112381A1
公开(公告)日：2011-05-12
申请号：US12971455
申请日：2010-12-17
申请人： Felice Sun , Benjamin D. Pless , Barbara Gibb
发明人： Felice Sun , Benjamin D. Pless , Barbara Gibb
IPC分类号： A61B5/00
CPC分类号： A61B5/4812 , A61B5/01 , A61B5/0205 , A61B5/02438 , A61B5/026 , A61B5/04012 , A61B5/0452 , A61B5/0476 , A61B5/0478 , A61B5/11 , A61B5/1118 , A61B5/14551 , A61B5/4815 , A61B5/686 , A61N1/36082 , A61N1/36135 , G06F19/00
摘要： Described here are implantable devices and methods for monitoring physiological information relating to sleep. The implantable devices are generally designed to include at least one sensor for sensing physiological information, a processor for processing the physiological information using low computational power to detect a sleep stage, and a battery. The detected sleep stage information may then be used to indicate sleep quality, identify or monitor a medical condition, or guide treatment thereof.

7. 发明申请

US20090326610A1 Systems and methods for interacting with an implantable medical device 有权
标题翻译：用于与可植入医疗装置相互作用的系统和方法
公开(公告)号：US20090326610A1
公开(公告)日：2009-12-31
申请号：US12554959
申请日：2009-09-07
申请人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R.M. Upton
发明人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R.M. Upton
IPC分类号： A61N1/08
CPC分类号： A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
摘要： An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.
摘要翻译：交互式可植入医疗装置系统包括可植入医疗装置和能够与可植入医疗装置进行双向通信和相互作用的网络使能的外部装置。外部设备被编程为与其他类似启用的设备进行交互。该系统通过消除对植入式医疗设备询问和编程的不必要的地理限制，以及允许患者，医生和其他用户访问医疗记录，历史和信息以及随时接收状态和护理相关的警报和消息来促进改善患者护理可以访问通信网络。

8. 发明授权

US08140160B2 Systems and methods for interacting with an implantable medical device 有权
标题翻译：用于与可植入医疗装置相互作用的系统和方法
公开(公告)号：US08140160B2
公开(公告)日：2012-03-20
申请号：US11436190
申请日：2006-05-16
申请人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R. M. Upton
发明人： Benjamin D. Pless , David R. Fischell , Barbara Gibb , Lisa Guzzo , Adrian R. M. Upton
IPC分类号： A61N1/36
CPC分类号： A61B5/076 , A61B5/0006 , A61B5/0031 , A61B5/0478 , A61B5/0482 , A61B5/4094 , A61B5/686 , A61B5/742 , A61B5/7475 , A61N1/36064 , A61N1/36135 , A61N1/37252 , A61N1/37258 , A61N1/37282 , G06F19/00
摘要： An interactive implantable medical device system includes an implantable medical device and a network-enabled external device capable of bi-directional communication and interaction with the implantable medical device. The external device is programmed to interact with other similarly-enabled devices. The system facilitates improved patient care by eliminating unnecessary geographic limitations on implantable medical device interrogation and programming, and by allowing patients, physicians, and other users to access medical records, history, and information and to receive status and care-related alerts and messages anywhere there is access to a communications network.
摘要翻译：交互式可植入医疗装置系统包括能够与可植入医疗装置进行双向通信和交互的可植入医疗装置和能够启用网络的外部装置。外部设备被编程为与其他类似启用的设备进行交互。该系统通过消除对植入式医疗设备询问和编程的不必要的地理限制，以及允许患者，医生和其他用户访问医疗记录，历史和信息以及随时接收状态和护理相关的警报和消息来促进改善患者护理可以访问通信网络。

9. 发明授权

US07813793B2 Seizure sensing and detection using an implantable device 有权
标题翻译：使用可植入装置进行检测和检测
公开(公告)号：US07813793B2
公开(公告)日：2010-10-12
申请号：US10973091
申请日：2004-10-25
申请人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
发明人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
IPC分类号： A61B5/00
CPC分类号： A61B5/4094 , A61B5/04012 , A61B5/0476 , A61B5/0478 , A61B5/6868 , A61B5/7203 , A61B5/7242 , A61B5/7246 , A61B5/7264 , A61B5/7275 , G06F19/00
摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.
摘要翻译：使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积在从患者的大脑接收的电图信号中波形的曲线）。根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应作用。

10. 发明授权

US06810285B2 Seizure sensing and detection using an implantable device 有权
标题翻译：使用可植入装置进行检测和检测
公开(公告)号：US06810285B2
公开(公告)日：2004-10-26
申请号：US09896092
申请日：2001-06-28
申请人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh K. Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
发明人： Benjamin D. Pless , Stephen T. Archer , Craig M. Baysinger , Barbara Gibb , Suresh K. Gurunathan , Bruce Kirkpatrick , Thomas K. Tcheng
IPC分类号： A61B50476
CPC分类号： A61B5/4094 , A61B5/04012 , A61B5/0476 , A61B5/0478 , A61B5/6868 , A61B5/7203 , A61B5/7242 , A61B5/7246 , A61B5/7264 , A61B5/7275 , G06F19/00
摘要： A system and method for detecting and predicting neurological events with an implantable device uses a relatively low-power central processing unit in connection with signal processing circuitry to identify features (including half waves) and calculate window-based characteristics (including line lengths and areas under the curve of the waveform) in an electrographic signal received from a patient's brain. The features and window-based characteristics are combinable in various ways according to the invention to detect and predict neurological events in real time, enabling responsive action by the implantable device.
摘要翻译：使用可植入装置检测和预测神经病学的系统和方法使用与信号处理电路相关联的相对低功率的中央处理单元来识别特征（包括半波）并计算基于窗口的特征（包括线路长度和面积在从患者的大脑接收的电图信号中波形的曲线）。根据本发明的特征和基于窗口的特征可以以各种方式组合以实时检测和预测神经病学事件，从而能够实现可植入装置的响应作用。

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