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1. 发明授权

US08403983B2 Heart valve 有权
标题翻译：心脏瓣膜
公开(公告)号：US08403983B2
公开(公告)日：2013-03-26
申请号：US12569856
申请日：2009-09-29
申请人： Arshad Quadri , J. Brent Ratz
发明人： Arshad Quadri , J. Brent Ratz
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2403 , A61F2/2409 , A61F2/2412 , A61F2/2415 , A61F2/848 , A61F2002/8483 , A61F2002/8486 , A61F2210/0076 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , Y10T29/49426
摘要： A replacement heart valve can comprise a valve body and an elongate frame. The valve body can define a plurality of leaflets adapted to move between an open state and a coapted state. The elongate frame can be configured to move between a radially compacted state and a radially expanded state, the frame comprising a plurality of struts. Stitches attach the valve body to the plurality of struts. At least one of the stitches can be a loose stitch configured to freely slide over the corresponding strut when the frame is moved between the radially compacted and radially expanded states.
摘要翻译：替换心脏瓣膜可包括阀体和细长框架。阀体可以限定适于在打开状态和受压状态之间移动的多个传单。细长框架可构造成在径向压实状态和径向膨胀状态之间移动，框架包括多个支柱。接头将阀体附接到多个支柱。当框架在径向压实和径向膨胀状态之间移动时，至少一个线圈可以是构造成在相应的支柱上自由滑动的松线圈。

2. 发明授权

US5133725A Adjustable intra-liminal valvulotome 失效
标题翻译：可调节内侧瓣膜瓣切开术
公开(公告)号：US5133725A
公开(公告)日：1992-07-28
申请号：US614114
申请日：1990-11-16
申请人： Arshad Quadri
发明人： Arshad Quadri
IPC分类号： A61B17/22
CPC分类号： A61B17/32075 , A61B2017/22097
摘要： An adjustable intraluminal valvulotome comprises a hollow tubular member and a pair of substantially identical, opposed cutting blades provided at the distal end of the tubular member. Each of the cutting blades has a first cutting blade at its trailing edge and a second cutting blade at one side generally transverse to the first cutting blade. The outer faces of the cutting blades have a complex convex surface. The cutting blades are movable between an extended position and a retracted postion with respect to the distal end of the tubular member and between an open position in which the cutting blades are spaced apart from each other and a closed position in which said cutting blades are drawn tightly against each other, by the operation of a pair of spring wires respectively attached to the cutting blades and slidable within the tubular member. The distal end of the tubular member is provided with a receptacle for receiving the first cutting edges of the cutting blades in the retracted position. A coil spring can be provided within the tubular member, through which the spring wires pass, to facilitate movement of the cutting blades between their open and closed positions.
摘要翻译：可调节的腔内瓣膜切开机包括中空管状构件和设置在管状构件的远端处的一对基本相同的相对的切割刀片。每个切割刀片在其后缘具有第一切割刀片，并且在一侧的大致横向于第一切割刀片的第二切割刀片。切割刀片的外表面具有复杂的凸面。切割刀片可相对于管状构件的远端在延伸位置和缩回位置之间以及切割刀片彼此间隔开的打开位置和在其中绘制所述切割刀片的关闭位置之间移动通过分别附接到切割刀片并可在管状构件内滑动的一对弹簧丝的操作彼此紧密地抵靠。管状构件的远端设置有用于在缩回位置接收切割刀片的第一切削刃的容器。螺旋弹簧可以设置在管状构件内，弹簧丝通过该螺旋弹簧，以便于切割刀片在其打开和关闭位置之间移动。

3. 发明授权

US5049154A Adjustable intra-luminal valvulotome 失效
标题翻译：可调节腔内瓣膜切开术
公开(公告)号：US5049154A
公开(公告)日：1991-09-17
申请号：US390410
申请日：1989-08-07
申请人： Arshad Quadri
发明人： Arshad Quadri
IPC分类号： A61B17/22
CPC分类号： A61B17/32075 , A61B2017/22097
摘要： An adjustable intraluminal valvulotome including a hollow tubular member in which is slidably disposed a control wire. First and second spring wire elements respectively interconnect first and second cutting blades having first and second perpendicular cutting edges to one end of the control wire. There is a handle member proximate the other end of the control wire for controlling longitudinal movement of the control wire in and out of the tubular member. The handle member enables the first and second cutting blades to move from a first extended cutting position to a second retracted position. A receptacle at the distal end of the tubular member restrains the cutting blades in a fully retracted non-cutting position and prevents their engagement with the vein or valves. A method of using a valvulotome to rupture and render inoperative the valves is also disclosed.
摘要翻译：一种可调节的腔内瓣膜切开机，其包括中空管状构件，其中可滑动地设置控制线。第一和第二弹簧丝元件将具有第一和第二垂直切削刃的第一和第二切割刀片分别互连到控制线的一端。在控制线的另一端附近有一个手柄构件，用于控制控制线进出管状构件的纵向运动。手柄构件使得第一和第二切割刀片能够从第一延伸切割位置移动到第二缩回位置。在管状构件的远端处的容器限制切割刀片处于完全缩回的非切割位置并防止它们与静脉或阀门的接合。还公开了使用瓣膜切开术破裂并使瓣膜不起作用的方法。

4. 发明授权

US09730790B2 Replacement valve and method 有权
公开(公告)号：US09730790B2
公开(公告)日：2017-08-15
申请号：US13403929
申请日：2012-02-23
申请人： Arshad Quadri , J. Brent Ratz , Robrecht Michiels
发明人： Arshad Quadri , J. Brent Ratz , Robrecht Michiels
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2412 , A61F2/2427 , A61F2/2439 , A61F2210/0014 , A61F2210/0076 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2250/0039 , A61F2250/006 , A61F2250/0069 , A61F2250/0071
摘要： A replacement valve has an expandable frame configured to engage a native valve and a valve body mounted to the expandable frame. The valve body can have a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and prevent flow in a second direction, the second direction being opposite the first direction.

5. 发明授权

US09433514B2 Method of securing a prosthesis 有权
标题翻译：固定假体的方法
公开(公告)号：US09433514B2
公开(公告)日：2016-09-06
申请号：US13346593
申请日：2012-01-09
申请人： Arshad Quadri
发明人： Arshad Quadri
IPC分类号： A61F2/24 , A61F2/82 , A61F2/915 , A61F2/848
CPC分类号： A61F2/82 , A61F2/2418 , A61F2/915 , A61F2002/8483 , A61F2002/8486 , A61F2002/91541 , A61F2002/91558 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要： A method of securing a prosthesis atraumatically to body tissue can include one or more of the following steps. A prosthesis can be delivered into a patient. The prosthesis may include an expandable frame. The frame can be expanded within a body cavity of the patient. Expansion of the frame can causes respective ends of both proximal prongs and distal prongs to draw closer together to grasp native tissue between the respective ends of the proximal prongs and distal prongs.
摘要翻译：将假体固定在身体组织上的方法可以包括一个或多个以下步骤。假体可以输送到患者体内。假体可以包括可扩张框架。框架可以在患者体腔内扩张。框架的扩张可使两个近端尖端和远端尖端的相应末端更靠近在一起，以抓住近端尖端和远端尖端的相应末端之间的天然组织。

6. 发明授权

US08414644B2 Vascular implant and delivery system 有权
标题翻译：血管植入和输送系统
公开(公告)号：US08414644B2
公开(公告)日：2013-04-09
申请号：US12761349
申请日：2010-04-15
申请人： Arshad Quadri , J. Brent Ratz
发明人： Arshad Quadri , J. Brent Ratz
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/24 , A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2/2439 , A61F2/95 , A61F2002/9522 , A61F2002/9534 , A61F2220/0016 , A61F2220/0033 , A61F2220/0075 , A61F2230/0013 , A61F2250/001
摘要： A compacted vascular implant can be delivered to a target location within a delivery device. During delivery, the implant can be partially released from the delivery device before full deployment. The delivery device can include an elongated support tube, a locking mechanism, and a sheath. The locking mechanism can be provided on the support tube. The sheath can be configured to slide over the elongated support tube and can be configured to cover the locking mechanism and to restrain at least a portion of the implant.
摘要翻译：压实的血管植入物可以递送到输送装置内的目标位置。在输送期间，在完全展开之前，植入物可以从输送装置部分地释放。输送装置可以包括细长支撑管，锁定机构和护套。锁定机构可以设置在支撑管上。护套可以被配置成在细长支撑管上滑动，并且可以构造成覆盖锁定机构并且限制植入物的至少一部分。

7. 发明授权

US08337541B2 Delivery system for vascular implant 有权
标题翻译：输血系统用于血管植入
公开(公告)号：US08337541B2
公开(公告)日：2012-12-25
申请号：US12572180
申请日：2009-10-01
申请人： Arshad Quadri , J. Brent Ratz
发明人： Arshad Quadri , J. Brent Ratz
IPC分类号： A61F2/84
CPC分类号： A61F2/246 , A61F2/2418 , A61F2/243 , A61F2/2439 , A61F2/95 , A61F2002/9505 , A61F2002/9511 , A61F2002/9517 , A61F2220/0075 , A61F2230/0054 , A61F2230/0067
摘要： A medical treatment system and method of treatment is described having an implant that can be positioned and deployed, then undeployed to allow repositioning of the implant. The system includes a self-expanding medical implant that longitudinally foreshortens upon radially expanding from a radially compacted state, a distal interface configured to attach the implant to a distal mount of a delivery device, and a proximal interface configured to attach the implant to a proximal mount of the delivery device. Moving the distal mount longitudinally away from the proximal mount applies a longitudinal tension to the implant causing the implant to expand longitudinally and contract radially, and moving the distal mount toward the proximal mount reduces a longitudinal tension in the implant allowing the implant to expand radially toward a fully expanded state.
摘要翻译：描述了一种治疗系统和治疗方法，其具有能够定位和展开的植入物，然后去除部署以允许植入物的重新定位。该系统包括自动扩张的医用植入物，其在从径向压实状态径向膨胀时纵向缩短，构造成将植入物附接到输送装置的远端安装件的远端界面，以及被配置为将植入物附接到近端输送装置的安装。将远端安装件纵向远离近侧安装件移动，对植入物施加纵向张力，使得植入物纵向膨胀并径向收缩，并使远端安装件向近端安装件移动，减小了植入物中的纵向张力，使植入物径向扩张一个完全扩张的状态。

8. 发明申请

US20120179239A1 VASCULAR PROSTHESIS CONNECTING STENT 有权
标题翻译：血管生成连接支架
公开(公告)号：US20120179239A1
公开(公告)日：2012-07-12
申请号：US13346593
申请日：2012-01-09
申请人： Arshad Quadri
发明人： Arshad Quadri
IPC分类号： A61F2/82
CPC分类号： A61F2/82 , A61F2/2418 , A61F2/915 , A61F2002/8483 , A61F2002/8486 , A61F2002/91541 , A61F2002/91558 , A61F2220/0016 , A61F2230/0013 , A61F2230/0054
摘要： An expandable vascular stent includes an m 3 n array of ovals formed in a cylinder, m being the number of columns of ovals in the circumferential direction and n being the number of rows of ovals in the axial direction, and a plurality of prongs extending inwardly from the outer ends of respective ovals in rows 1 and n of the m 3 n array, and being arranged in facing pairs extending from axially-aligned ovals. The cylinder is expandable from an initial diameter to a pre-determined final diameter, wherein an increase in the diameter of the stent results in a substantial decrease in the length of the stent. The tube and the prongs can be made of surgical stainless steel, the tube being expandable using an angioplasty balloon; or the tube and the prongs can be made of a memory metal and the tube is self-expanding.
摘要翻译：可扩张血管支架包括形成在圆筒中的m 3 n椭圆形阵列，m是圆周方向上椭圆的列数，n是椭圆形在轴向方向上的行数，以及向内延伸的多个尖头从m 3 n阵列的行1和n中的相应椭圆形的外端，并且以从轴向对齐的椭圆形延伸的面对对布置。圆柱体从初始直径扩展到预定的最终直径，其中支架直径的增加导致支架长度的显着减小。管和插脚可以由手术不锈钢制成，管可以使用血管成形术气囊扩张; 或者管子和插脚可以由记忆金属制成，并且管子是自膨胀的。

9. 发明申请

US20100298931A1 VASCULAR IMPLANT AND DELIVERY SYSTEM 有权
标题翻译：血管植入和输送系统
公开(公告)号：US20100298931A1
公开(公告)日：2010-11-25
申请号：US12761349
申请日：2010-04-15
申请人： Arshad Quadri , J. Brent Ratz
发明人： Arshad Quadri , J. Brent Ratz
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2/24 , A61F2/2418 , A61F2/243 , A61F2/2436 , A61F2/2439 , A61F2/95 , A61F2002/9522 , A61F2002/9534 , A61F2220/0016 , A61F2220/0033 , A61F2220/0075 , A61F2230/0013 , A61F2250/001
摘要： A vascular implant for replacing a native heart valve comprises a self expanding stent supporting a valve body having leaflets. The stent preferably comprises an anchoring structure configured to prevent the implant from passing through the valve annulus. For delivery, the implant is compacted within a delivery device and secured at one end. During delivery the implant is partially released from the delivery device, and positioning of the implant is verified prior to full release. The implant can be at least partially resheathed and repositioned if desired.
摘要翻译：用于替换天然心脏瓣膜的血管植入物包括支撑具有传单的阀体的自扩张支架。支架优选地包括构造成防止植入物通过瓣膜环的锚定结构。为了交付，植入物在输送装置内压实并固定在一端。在输送期间，植入物部分地从输送装置释放，并且在完全释放之前验证植入物的定位。如果需要，植入物可以至少部分地重新固定并重新定位。

10. 发明申请

US20120215303A1 REPLACEMENT HEART VALVE AND METHOD 有权
标题翻译：更换心瓣和方法
公开(公告)号：US20120215303A1
公开(公告)日：2012-08-23
申请号：US13403929
申请日：2012-02-23
申请人： Arshad Quadri , J. Brent Ratz , Robrecht Michiels
发明人： Arshad Quadri , J. Brent Ratz , Robrecht Michiels
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/24 , A61F2/2412 , A61F2/2427 , A61F2/2439 , A61F2210/0014 , A61F2210/0076 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2250/0039 , A61F2250/006 , A61F2250/0069 , A61F2250/0071
摘要： A replacement heart valve has an expandable frame configured to engage a native valve annulus and a valve body mounted to the expandable frame. The valve body can have a plurality of valve leaflets configured to open to allow flow in a first direction and engage one another so as to close and prevent flow in a second direction, the second direction being opposite the first direction.
摘要翻译：替换心脏瓣膜具有被构造成接合天然瓣膜环的可膨胀框架和安装到可扩张框架的阀体。阀体可以具有多个阀单元，其构造成打开以允许在第一方向上流动并且彼此接合，以便关闭并防止在第二方向上流动，第二方向与第一方向相反。

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