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1. 发明授权

US08768484B2 High-voltage CMOS neuroelectronic interface for a multichannel vestibular prosthesis 有权
标题翻译：用于多通道前庭假体的高压CMOS神经电子界面
公开(公告)号：US08768484B2
公开(公告)日：2014-07-01
申请号：US13812107
申请日：2011-07-26
申请人： Charles Coleman Della Santina , Andreas Andreou , Zaven Kalayjian , Gene Fridman , Bryce Chiang , Julius Georgiou
发明人： Charles Coleman Della Santina , Andreas Andreou , Zaven Kalayjian , Gene Fridman , Bryce Chiang , Julius Georgiou
IPC分类号： A61N1/05
CPC分类号： A61N1/3727 , A61B5/11 , A61B5/6847 , A61B2562/0219 , A61N1/0526 , A61N1/0541 , A61N1/36036
摘要： A multichannel vestibular prosthesis includes a sensor system and a microcontroller configured to communicate with the sensor system to receive sensor signals from the sensor system while in operation. The microcontroller is configured to provide control signals in response to the sensor signals. The multichannel vestibular prosthesis also includes a neuroelectronic interface integrated circuit configured to communicate with the microcontroller to receive the control signals, and a plurality of electrodes electrically connected to the neuroelectronic interface integrated circuit. The neuroelectronic interface integrated circuit includes a digital controller configured to communicate with the microcontroller, a plurality of digital-to-analog converters configured to communicate with the digital controller, and a plurality of analog current control circuits, each constructed to communicate with a respective one of the plurality of digital-to-analog converters. Each of the plurality of analog current control circuits can be electrically connected directly or under software control to a respective one of a plurality of electrodes for delivering electrical stimuli to at least one vestibular nerve, and the digital controller is configured to control amplitudes, frequencies, polarities and durations of currents to be delivered to any combination of the plurality of electrical leads.
摘要翻译：多通道前庭假体包括传感器系统和被配置为与传感器系统通信的微控制器，以在操作中从传感器系统接收传感器信号。微控制器被配置为响应于传感器信号提供控制信号。多通道前庭假体还包括被配置为与微控制器通信以接收控制信号的神经电子接口集成电路，以及电连接到神经电子接口集成电路的多个电极。神经电子接口集成电路包括被配置为与微控制器进行通信的数字控制器，被配置为与数字控制器进行通信的多个数模转换器，以及多个模拟电流控制电路，每个模拟电流控制电路被构造为与相应的一个通信的多个数模转换器。多个模拟电流控制电路中的每一个可以直接地或在软件控制下电连接到多个电极中的相应一个电极，用于将电刺激递送到至少一个前庭神经，并且数字控制器被配置为控制幅度，频率，电流的极性和持续时间被输送到多个电引线的任何组合。

2. 发明申请

US20130131761A1 HIGH-VOLTAGE CMOS NEUROELECTRONIC INTERFACE FOR A MULTICHANNEL VESTIBULAR PROSTHESIS 有权
标题翻译：用于多通道VESTIBULAR PROSTHISIS的高压CMOS神经电接口
公开(公告)号：US20130131761A1
公开(公告)日：2013-05-23
申请号：US13812107
申请日：2011-07-26
申请人： Charles Coleman Della Santina , Andreas Andreou , Zaven Kalayjian , Gene Fridman , Bryce Chiang , Julius Georgiou
发明人： Charles Coleman Della Santina , Andreas Andreou , Zaven Kalayjian , Gene Fridman , Bryce Chiang , Julius Georgiou
IPC分类号： A61N1/372 , A61N1/00
CPC分类号： A61N1/3727 , A61B5/11 , A61B5/6847 , A61B2562/0219 , A61N1/0526 , A61N1/0541 , A61N1/36036
摘要： A multichannel vestibular prosthesis includes a sensor system and a microcontroller configured to communicate with the sensor system to receive sensor signals from the sensor system while in operation. The microcontroller is configured to provide control signals in response to the sensor signals. The multichannel vestibular prosthesis also includes a neuroelectronic interface integrated circuit configured to communicate with the microcontroller to receive the control signals, and a plurality of electrodes electrically connected to the neuroelectronic interface integrated circuit. The neuroelectronic interface integrated circuit includes a digital controller configured to communicate with the microcontroller, a plurality of digital-to-analog converters configured to communicate with the digital controller, and a plurality of analog current control circuits, each constructed to communicate with a respective one of the plurality of digital-to-analog converters. Each of the plurality of analog current control circuits can be electrically connected directly or under software control to a respective one of a plurality of electrodes for delivering electrical stimuli to at least one vestibular nerve, and the digital controller is configured to control amplitudes, frequencies, polarities and durations of currents to be delivered to any combination of the plurality of electrical leads.
摘要翻译：多通道前庭假体包括传感器系统和被配置为与传感器系统通信的微控制器，以在操作中从传感器系统接收传感器信号。微控制器被配置为响应于传感器信号提供控制信号。多通道前庭假体还包括被配置为与微控制器通信以接收控制信号的神经电子接口集成电路，以及电连接到神经电子接口集成电路的多个电极。神经电子接口集成电路包括被配置为与微控制器进行通信的数字控制器，被配置为与数字控制器通信的多个数模转换器，以及多个模拟电流控制电路，每个模拟电流控制电路被构造成与相应的一个通信的多个数模转换器。多个模拟电流控制电路中的每一个可以直接地或在软件控制下电连接到多个电极中的相应一个电极，用于将电刺激递送到至少一个前庭神经，并且数字控制器被配置为控制幅度，频率，电流的极性和持续时间被输送到多个电引线的任何组合。

3. 发明申请

US20060193356A1 Die level optical transduction systems 审中-公开
标题翻译：晶片光学转导系统
公开(公告)号：US20060193356A1
公开(公告)日：2006-08-31
申请号：US11333498
申请日：2006-01-17
申请人： Robert Osiander , Andreas Andreou , Francisco Tejada , Danielle Wesolek , Joseph Miragliotta , Philippe Pouliquen , Dennis Wickenden
发明人： Robert Osiander , Andreas Andreou , Francisco Tejada , Danielle Wesolek , Joseph Miragliotta , Philippe Pouliquen , Dennis Wickenden
IPC分类号： H01S3/00 , G01B9/02
CPC分类号： G01B9/02051 , G01B9/02023 , G01B9/02067 , G01B2290/25 , G01D5/266
摘要： A scalable architecture based in silicon on sapphire (SOS) CMOS for building an interferometric optical detection system to sense the motion of a resonating MEMS device or to detect the motion of any object to which the system is packaged. The SOS CMOS device is packaged with both vertical cavity surface emitting lasers (VCSELs) and MEMS devices. The optical transparency of the sapphire substrate together with the ultra thin silicon PIN photodiodes available in the SOS process allows for the design of both a Michelson-type and Fabry-Perot-type interferometer. The detectors, signal processing electronics and VCSEL drivers are built on the SOS CMOS for a complete system.
摘要翻译：一种基于蓝宝石（SOS）CMOS的可扩展架构，用于构建干涉光学检测系统，以感测谐振MEMS器件的运动或检测系统所封装的任何对象的运动。 SOS CMOS器件与垂直腔表面发射激光器（VCSEL）和MEMS器件封装。蓝宝石衬底的光学透明度与SOS工艺中可用的超薄硅PIN光电二极管一起允许设计迈克尔逊型和法布里 - 珀罗型干涉仪。检测器，信号处理电子设备和VCSEL驱动器都建立在SOS CMOS上，用于完整的系统。

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