专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

81. 发明申请

US20050175707A1 Process of forming and modifying particles and compositions produced thereby 失效
公开(公告)号：US20050175707A1
公开(公告)日：2005-08-11
申请号：US10512345
申请日：2003-04-23
申请人： James Talton , Christopher McConville
发明人： James Talton , Christopher McConville
IPC分类号： A61K9/00 , A61K9/14 , A61K9/16 , A61K9/51 , B01J2/18 , B01J13/04
CPC分类号： A61K9/0075 , A61K9/0043 , A61K9/14 , A61K9/145 , A61K9/146 , A61K9/1688 , A61K9/1694 , A61K9/5138 , A61K9/5146 , A61K9/5153 , A61K9/5192 , B01J2/18 , B01J13/04
摘要： The present invention relates to processes for forming particles including drugs in a solution, changing the bulk or surface properties of a drug particle, and/or microencapsulation drug particles, and compositions produced thereby. In some embodiments, the process described utilized mechanical agitation, more specifically low-frequency sonication, under controlled conditions, which provides mild shear forces during forming and/or precipitation to control the particle growth and mixing properties. Particle size can range from less than about 200 nanometers to greater than about one millimeter, depending on the processing conditions and application. The process described can be used to form a drug particle suspension, dry a wet powder slurry or suspension, as well as to improve the surface properties of the particle through conditioning the structure of the particle or particle surface and/or annealing the particle or particle surface. Annealing or conditioning drug particles may be used to force an amorphous to crystalline transition, creating a more stable powder, or smooth a particle surface. In addition, the process can be used to microencapsulate particles by suspending the microparticles in a non-solvent including a coating material (such as a biodegradable polymer) under controlled process conditions. The powder compositions produced thereby possess improved properties including, but not limited to, improved flow and dispersibility, controlled bioadhesion, stability, resistance to moisture, dissolution/release profiles, and/or bioavailabilities. This process, and the compositions produced, provide significant advantages in the manufacture of pharmaceutical particulate formulations, as well as biomedical, diagnostic, and chromatography particulate compositions, where sensitive macromolecules, such as proteins or DNA, are involved that would be degraded using more rigorous processing conditions or temperatures.

82. 发明申请

US20050100666A1 AEROSOL METHOD AND APPARATUS, COATED PARTICULATE PRODUCTS, AND ELECTRONIC DEVICES MADE THEREFROM 失效
标题翻译：气溶胶方法和装置，涂层颗粒产品及其制造的电子设备
公开(公告)号：US20050100666A1
公开(公告)日：2005-05-12
申请号：US10904257
申请日：2004-11-01
申请人： Mark Hampden-Smith , Toivo Kodas , Quint Powell , Daniel Skamser , James Caruso , Clive Chandler
发明人： Mark Hampden-Smith , Toivo Kodas , Quint Powell , Daniel Skamser , James Caruso , Clive Chandler
IPC分类号： B01J2/00 , B01J2/02 , B01J2/04 , B01J2/16 , B01J2/18 , B01J13/02 , B01J19/00 , B01J19/10 , B01J19/24 , B22F1/00 , B22F1/02 , B22F9/02 , B22F9/24 , B24B37/04 , C01B13/18 , C01B17/20 , C01G15/00 , C01G23/00 , C01G25/00 , C09G1/02 , C09K3/14 , C09K11/02 , C09K11/08 , C09K11/56 , C09K11/58 , C09K11/59 , C09K11/62 , C09K11/64 , C09K11/66 , C09K11/67 , C09K11/77 , C22C1/10 , C22C32/00 , H01G4/008 , H01J29/20 , H01L21/321 , H01L23/498 , B29B9/00 , B05D7/00
CPC分类号： B01J2/003 , B01J2/006 , B01J2/02 , B01J2/04 , B01J13/02 , B01J19/10 , B01J19/2405 , B01J2219/00112 , B01J2219/00155 , B01J2219/00159 , B01J2219/00162 , B01J2219/00166 , B01J2219/00171 , B01J2219/00186 , B22F1/0018 , B22F1/02 , B22F1/025 , B22F9/02 , B22F9/026 , B22F9/24 , B22F9/30 , B22F2998/00 , B22F2999/00 , B24B37/044 , B82Y30/00 , C01B13/18 , C01B13/185 , C01B17/20 , C01G15/006 , C01G23/003 , C01G23/006 , C01G25/00 , C01P2002/60 , C01P2002/70 , C01P2004/03 , C01P2004/32 , C01P2004/34 , C01P2004/50 , C01P2004/52 , C01P2004/61 , C01P2004/62 , C01P2004/80 , C01P2006/10 , C01P2006/22 , C01P2006/60 , C01P2006/80 , C09G1/02 , C09K3/1436 , C09K3/1463 , C09K11/025 , C09K11/0805 , C09K11/0877 , C09K11/562 , C09K11/565 , C09K11/567 , C09K11/584 , C09K11/595 , C09K11/623 , C09K11/625 , C09K11/642 , C09K11/643 , C09K11/644 , C09K11/662 , C09K11/666 , C09K11/671 , C09K11/672 , C09K11/7701 , C09K11/7708 , C09K11/7718 , C09K11/7729 , C09K11/7731 , C09K11/7734 , C09K11/7746 , C09K11/7769 , C09K11/7771 , C09K11/7774 , C09K11/7776 , C09K11/7784 , C09K11/7786 , C09K11/7787 , C09K11/7789 , C09K11/7797 , C22C1/1026 , C22C32/0089 , H01G4/0085 , H01J29/20 , H01L21/3212 , H01L23/49883 , H01L2924/0002 , H01L2924/09701 , Y10T428/12007 , Y10T428/12014 , Y10T428/12056 , Y10T428/1216 , Y10T428/12181 , Y10T428/256 , Y10T428/2982 , Y10T428/2991 , B22F1/0014 , B22F1/0048 , B22F2202/01 , B22F3/008 , B22F2202/11 , H01L2924/00
摘要： Provided is an aerosol method, and accompanying apparatus, for preparing powdered products of a variety of materials involving the use of an ultrasonic aerosol generator (106) including a plurality of ultrasonic transducers (120) underlying and ultrasonically energizing a reservoir of liquid feed(102) which forms droplets of the aerosol. Carrier gas (104) is delivered to different portions of the reservoir by a plurality of gas delivery ports (136) delivering gas from a gas delivery system. The aerosol is pyrolyzed to form particles, which are then cooled and collected. The invention also provides powders that include coated particles made by the method and devices made using the coated particles.
摘要翻译：提供了一种用于制备各种材料的粉末产品的气溶胶方法和配套装置，其涉及使用超声波气溶胶发生器（106），所述超声波气溶胶发生器包括多个超声换能器（120），所述多个超声波换能器在液体进料（102）），其形成气溶胶的液滴。载气（104）通过从气体输送系统输送气体的多个气体输送口（136）输送到储存器的不同部分。气溶胶被热解形成颗粒，然后将其冷却并收集。本发明还提供了包括通过该方法制备的涂覆颗粒和使用涂覆颗粒制备的装置的粉末。

83. 发明授权

US5937910A Linings for pipelines and passageways 失效
标题翻译：管道和通道衬
公开(公告)号：US5937910A
公开(公告)日：1999-08-17
申请号：US557067
申请日：1995-11-13
申请人： Brian Burnett Chandler
发明人： Brian Burnett Chandler
IPC分类号： F16L55/16 , B01J2/18 , B01J13/02 , B29C35/02 , B29C35/08 , B29C63/00 , B29C63/36 , B29C67/24 , B29C70/58 , B29K101/10 , B29L23/00 , C08K7/16 , C08L101/00 , F16L55/165
CPC分类号： B29C70/58 , B01J13/02 , B01J2/18 , B29C35/08 , B29C63/0069 , B29C67/247 , F16L55/1656 , B29C2035/0811 , B29C35/0261 , B29C63/00 , B29K2105/0014 , B29K2105/16 , B29L2023/006
摘要： The invention provides that flexible lining tubes for application to underground pipelines and passageways comprise absorbent material which is impregnated with curable synthetic resin which can be cured when the tube is placed on the pipeline or passageway surface so that a rigid pipe within the pipe is formed. The curing of the resin is controlled by filling the curing agent into micropores or microporous particles which are dispersed throughout the resin. The curing agent is only released when the resin is subjected to applied energy such as sonic and/or heat energy. A preferred method is to include CURIE temperature magnetic particles in the resin and to excite (and thus heat) the magnetic particles by applying an alternating high frequency magnetic field. The heat from the magnetic particles opens the microporous particles and causes desorbence of the curing agent and then cure of the resin. The invention also provides that the curing agent is absorbed into the absorbent layer in the first place using sonic energy.
摘要翻译： PCT No.PCT / GB94 / 01453 Sec。 371日期：1995年11月13日 102（e）1995年11月13日PCT PCT 1994年7月5日PCT公布。出版物WO95 / 01861 日期1995年1月19日本发明提供用于地下管线和通道的挠性衬管包括浸渍有可固化合成树脂的吸收材料，当管被放置在管道或通道表面上时，可固化，使得刚性管内管道形成。通过将固化剂填充到分散在树脂中的微孔或微孔颗粒来控制树脂的固化。只有当树脂受到诸如声波和/或热能的施加能量时，固化剂才被释放。优选的方法是将CURIE温度磁性颗粒包括在树脂中并通过施加交替的高频磁场来激发（并因此加热）磁性颗粒。来自磁性颗粒的热量打开微孔颗粒并导致固化剂的脱附，然后固化树脂。本发明还提供了使用声能首先将固化剂吸收到吸收层中。

84. 发明授权

US5911741A Process and device to pelletize substances which can be dispensed in the form of drops 失效
标题翻译：可以以液滴形式分配的物质造粒的方法和装置
公开(公告)号：US5911741A
公开(公告)日：1999-06-15
申请号：US489815
申请日：1995-06-13
申请人： Gunther Weyermanns , Stefan Zerwas
发明人： Gunther Weyermanns , Stefan Zerwas
IPC分类号： B01J2/06 , B01J2/18 , F25C1/00 , F25D13/06
CPC分类号： F25C1/00 , B01J2/06 , B01J2/18
摘要： The invention relates to a process and an apparatus for pelleting materials capable of forming drops, in which the materials to be pelleted are added dropwise into a coolant liquid bath (5), preferably a liquified gas, hardened and are kept separate on a vibratory conveyor unit (7) with supply of vibratory energy and are completely frozen solid, exploiting the temperature of the cold gas.
摘要翻译：本发明涉及一种用于造粒能够形成液滴的材料的方法和设备，其中待沉淀的材料被逐滴加入冷却剂液体浴（5）中，优选液化气体，硬化，并在振动输送机单元（7）提供振动能量，完全冷冻固体，利用冷气的温度。

85. 发明授权

US5891212A Apparatus and method for making uniformly 失效
公开(公告)号：US5891212A
公开(公告)日：1999-04-06
申请号：US931295
申请日：1997-09-16
申请人： Jie Tang , Gary B. Hess , Mark D. Muszynski , Thomas S. Goehring
发明人： Jie Tang , Gary B. Hess , Mark D. Muszynski , Thomas S. Goehring
IPC分类号： B01J2/02 , B01J2/04 , B01J2/06 , B01J2/16 , B01J2/18 , B22F1/00 , B22F9/08 , B23K35/02 , C21D9/00 , H05K3/34 , B06B1/20
CPC分类号： B01J2/06 , B01J2/02 , B01J2/04 , B01J2/16 , B01J2/18 , B22F1/0048 , B22F9/08 , B23K35/0244 , C21D9/0068 , B22F2009/0816 , B22F2009/0836 , B22F2009/086 , B22F2009/0892 , B22F2998/00 , B22F2999/00 , C21D2281/02 , H05K3/3478
摘要： Uniform sized and shaped spheres are formed by applying a minute periodic disturbance to a low viscosity liquid material. Pressure forces the material through at least one orifice in a crucible as a steady laminar stream. The stream enters an enclosed controlled temperature solidification environment which contains at least one heat transfer medium. A charging means is applied to the stream as the stream exits the crucible and breaks into a plurality of spheres to deflect the spheres as they pass through an electric field. The enclosed controlled temperature solidification environment cools and substantially solidifies the spheres.

86. 发明授权

US5204162A Non-spherical bodies 失效
标题翻译：非球体
公开(公告)号：US5204162A
公开(公告)日：1993-04-20
申请号：US770369
申请日：1991-10-03
申请人： Thomas D. Ketcham
发明人： Thomas D. Ketcham
IPC分类号： B01J2/00 , B01J2/18 , B01J2/20 , B01J2/22
CPC分类号： B01J2/22 , B01J2/18 , Y10T428/12382 , Y10T428/24777 , Y10T428/2913 , Y10T428/2973 , Y10T428/2975 , Y10T428/2982
摘要： Non-spherical bodies having a circular cross-section that is 0.5-200 microns in diameter and that are longer than the cross-sectional diameter, and a method of making such bodies by reshaping non-spherical bodies. The method comprises positioning a monolayer of unsintered, deformable, spherical bodies between smooth facing surfaces on two flat formers, and applying a mild shearing force to at least one of the formers.

87. 发明授权

US4871489A Spherical particles having narrow size distribution made by ultrasonic vibration 失效
标题翻译：通过超声波振动制造的具有窄尺寸分布的球形颗粒
公开(公告)号：US4871489A
公开(公告)日：1989-10-03
申请号：US185298
申请日：1988-04-19
申请人： Thomas D. Ketcham
发明人： Thomas D. Ketcham
IPC分类号： B01J2/08 , B01J2/18
CPC分类号： B01J2/18 , B01J2/08
摘要： An apparatus and process for producing liquid droplets having a narrow size distribution. Thin liquid streams are forced under pressure through a plurality of orifices in an orifice plate, the largest of which orifices has a diameter not greater than about three times the diameter of the smallest of those orifices. Also the thin liquid streams are vibrated to cause the breakup of each stream into droplets having a narrow size distribution.
摘要翻译：一种用于生产具有窄尺寸分布的液滴的装置和方法。薄的液体流在压力下被迫穿过孔板中的多个孔，其中最大的孔具有不大于这些孔中最小孔的直径的大约三倍的直径。此外，薄的液体流被振动以使每个流分解成具有窄尺寸分布的液滴。

88. 发明授权

US3983740A Method and apparatus for forming a stream of identical drops at very high speed 失效
标题翻译：用于以非常高的速度形成相同液滴流的方法和装置
公开(公告)号：US3983740A
公开(公告)日：1976-10-05
申请号：US548097
申请日：1975-02-07
申请人： Francois Danel
发明人： Francois Danel
IPC分类号： B01J2/18 , B01J19/10 , B01L3/02 , B05B15/04 , B05B17/06 , B26F3/00 , G01N35/10 , G01N3/32
CPC分类号： B01L3/0268 , B01J19/10 , B01J2/18 , B05B15/0431 , B05B17/0607 , B26F3/004 , G01N2035/1041 , Y10T83/364
摘要： A method and apparatus for producing a very fast succession of identical well-defined drops, driven at very high speed, in which a jet of liquid which is divided into droplets by high-frequency vibration is produced at very high speed.
摘要翻译：以非常高的速度产生非常快速连续的相同且明确定义的液滴的方法和装置，其中通过高频振动被分成液滴的液体射流以非常高的速度产生。

89. 发明授权

US3933955A Process for producing microspheres 失效
标题翻译：微球制备方法
公开(公告)号：US3933955A
公开(公告)日：1976-01-20
申请号：US275236
申请日：1972-07-26
申请人： Wayne M. Lysher
发明人： Wayne M. Lysher
IPC分类号： B01J2/08 , B01J2/18 , B01J2/06
CPC分类号： B01J2/18 , B01J2/08
摘要： Process for producing microspheres comprises immersing a lower portion of a generally vertical, sol-gel feed tube having a lower microsphere formation needle in an alcohol drying column, feeding sol-gel at a predetermined rate into the upper end of the feed tube, and vibrating the feed tube in a generally horizontal direction at a predetermined amplitude and frequency to produce microspheres from the formation needle of a uniform and predetermined size. An electromagnetic transducer drive for vibrating the feed tube is used in one illustrative embodiment of apparatus for practicing the invention, and an electric motor offset drive is used in another illustrative embodiment of such apparatus. A feed tube having multiple microsphere formation needles at its lower end can be used for producing microspheres in quantity.
摘要翻译：制备微球的方法包括将具有下微球形成针的大体上垂直的溶胶 - 凝胶进料管的下部浸入醇干燥塔中，以预定速率将溶胶 - 凝胶进料到进料管的上端，并振动进料管以预定的振幅和频率在大致水平的方向上以从均匀和预定尺寸的地层针产生微球。在用于实施本发明的装置的一个说明性实施例中使用用于振动进料管的电磁换能器驱动器，并且在该装置的另一说明性实施例中使用电动机偏移驱动器。在其下端具有多个微球形成针的进料管可用于生产微球。

90. 发明授权

US3933954A Preparation of powders having spherical-shaped particles from ionomer resins and ethylene/carboxylic acid copolymer resins 失效
标题翻译：从离聚物树脂和乙烯/羧酸共聚物树脂制备具有球形颗粒的粉末
公开(公告)号：US3933954A
公开(公告)日：1976-01-20
申请号：US419894
申请日：1973-11-28
申请人： John Charles Gebhard, Jr. , Marion Glen Waggoner , James Lang Webster
发明人： John Charles Gebhard, Jr. , Marion Glen Waggoner , James Lang Webster
IPC分类号： C08J3/12 , B01J2/18
CPC分类号： C08J3/12 , C08J2357/00
摘要： Method whereby spherical-shaped copolymer particles having a rough surface are produced. In a closed shear zone of a shear device under positive pressure water, at least 0.6% by weight of ammonia, and up to 50% by weight of copolymers of alpha-olefins and alpha, beta-ethylenically unsaturated carboxylic acids having from 3 to 8 carbon atoms, and optionally an additional monoethylenically unsaturated monomer, the copolymer having from 0% to 90% of the carboxylic acid groups ionized by neutralization with metal ions, are sheared at a temperature above the melting point but below the thermal degradation point of the copolymer to form a homogeneous aqueous slurry wherein the copolymer particles have an average particle size of less than 100 microns. The slurry is maintained with agitation at a temperature above the copolymer melting point for at least 0.5 minute until substantially all the copolymer particles become spherical. Agitation is continued and the slurry is cooled to a temperature below about the copolymer freezing point over a period of at least 0.3 minute while the pressure is maintained at sufficient level to keep the water in the liquid state. The pressure of the cooled slurry is reduced to atmospheric pressure and the copolymer particles are separated from the aqueous component of the slurry. The spherical-shaped particles have an average diameter of 10 to 100 microns and the surface thereof is covered with hemispherical shaped bumps about 0.1 micron in diameter. The particles form a free-flowing powder useful in preparing clear, protective, shatter-resistant coatings for glass, and protective coatings for metals and other materials.
摘要翻译：制造具有粗糙表面的球形共聚物颗粒的方法。在剪切装置在正压水，至少0.6重量％的氨和高达50重量％的α-烯烃和α，β-烯键式不饱和羧酸的共聚物的封闭剪切区域中具有3至8个碳原子和任选的另外的单烯属不饱和单体，通过与金属离子中和而离子化的羧酸基团的0％至90％的共聚物在高于熔点但低于共聚物的热降解点的温度下剪切以形成均匀的含水浆料，其中共聚物颗粒的平均粒度小于100微米。将浆液在高于共聚物熔点的温度下搅拌保持至少0.5分钟，直到基本上所有的共聚物颗粒变成球形。搅拌持续，并将浆料在至少0.3分钟的时间内冷却至低于共聚物凝固点的温度，同时将压力保持在足够的水平以保持水处于液态。将冷却的浆料的压力降低至大气压，并将共聚物颗粒与浆料的水性组分分离。球形颗粒具有10至100微米的平均直径，并且其表面被直径约0.1微米的半球形凸起覆盖。颗粒形成自由流动的粉末，可用于制备玻璃的透明，防护，防碎涂层，以及金属和其他材料的保护涂层。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式