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    • 88. 发明授权
    • Phenanthroindolizidine derivative and NFκB inhibitor containing same as active ingredient
    • 菲咯啉二氮茚衍生物和含有与活性成分相同的NFkappaB抑制剂
    • US08569327B2
    • 2013-10-29
    • US13124554
    • 2009-10-23
    • Takashi IkedaSeigo SawadaTakashi YaegashiTakeshi MatsuzakiShusuke HashimotoRyuta Yamazaki
    • Takashi IkedaSeigo SawadaTakashi YaegashiTakeshi MatsuzakiShusuke HashimotoRyuta Yamazaki
    • A61K31/403C07D221/18
    • C07D471/04
    • A novel compound having an excellent NFκB inhibitory effect is provided. Specifically disclosed is a compound represented by the following formula (1) or a salt thereof: wherein, R1 represents a hydrogen atom, a lower alkyl group, or the like; R2 represents a hydrogen atom, a lower alkyl group, a halogen atom, or the like; R3 represents a hydrogen atom, a lower alkyl group, a hydroxyl group, or a halogen atom; R4 represents a hydrogen atom or a lower alkyloxy group; R5 represents a hydrogen atom, a lower alkyloxy group, a halogen atom, a hydroxyl group, or a methylenedioxy group formed together with R6 or an isopropylidenedioxy group formed together with R6; R6 represents a hydrogen atom, a lower alkyloxy group, or a methylenedioxy group formed together with R5 or an isopropylidenedioxy group formed together with R5; R7 represents a hydrogen atom or a lower alkyl group; and R8 represents a hydrogen atom, a hydroxyl group, an amino group, a lower alkylcarbonyloxy group, or a halogen atom.
    • 提供了具有优异NFκB抑制作用的新型化合物。 具体公开的是由下式(1)表示的化合物或其盐:其中,R1表示氢原子,低级烷基等; R2表示氢原子,低级烷基,卤素原子等; R3表示氢原子,低级烷基,羟基或卤素原子; R4表示氢原子或低级烷氧基; R5表示与R6一起形成的与R6或异丙烯二氧基一起形成的氢原子,低级烷氧基,卤素原子,羟基或亚甲二氧基; R6表示与R5一起形成的氢原子,低级烷氧基或亚甲二氧基,或与R5形成的异丙烯二氧基; R7表示氢原子或低级烷基; R8表示氢原子,羟基,氨基,低级烷基羰基氧基或卤素原子。
    • 89. 发明申请
    • Air-Conditioning Apparatus and Configuration of Installation of Same
    • 空调设备及其安装配置
    • US20130213614A1
    • 2013-08-22
    • US13399650
    • 2012-02-17
    • Takashi IkedaJoseph Paul BushTakashi OkazakiTomohiko Kasai
    • Takashi IkedaJoseph Paul BushTakashi OkazakiTomohiko Kasai
    • F28D15/00
    • F24F3/044F24F1/0014F24F1/0022F24F13/0209F24F2001/0037
    • An air-conditioning apparatus includes a body casing of an indoor unit formed in a substantially rectangular parallelepiped shape. The body casing is formed with a body inlet port on a body bottom, and a body outlet port is formed in each body side. The body casing houses a centrifugal fan, a fan motor rotatably driving the centrifugal fan, and an indoor heat exchanger disposed so as to surround an outer periphery of the centrifugal fan in planar view. In each of the body outlet port, a joint is protrudingly provided with a body-side duct connecting portion that connects a duct thereto. Further, outlet ports are formed. The air-conditioning apparatus includes a plurality of outlet units each protrudingly provided with an outlet-side duct connecting portion that connects the duct thereto. Furthermore, at least one of the joints is formed with a plurality of the body-side duct connecting portions.
    • 一种空调装置,其特征在于,具备形成为大致长方体的室内机的主体壳体。 主体壳体在主体底部形成有主体入口,并且在每个主体侧形成主体出口。 主体壳体容纳离心风扇,可旋转地驱动离心风扇的风扇马达,以及在平面图中围绕离心式风扇的外周配置的室内热交换器。 在本体出口的每一个中,接头突出地设置有将导管连接到其的主体侧管道连接部。 此外,形成出口。 空调装置包括多个出口单元,每个出口单元突出地设置有将管道连接到其的出口侧管道连接部分。 此外,至少一个接头形成有多个主体侧管道连接部。