会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 82. 发明申请
    • USER INTERFACE
    • 用户界面
    • US20120317515A1
    • 2012-12-13
    • US13579453
    • 2010-03-08
    • Wei WangKongqiao WangXiaohui XieYingfei LiuXia WangHuanglingzi LiuBin WangZhen LiuYuezhong Tang
    • Wei WangKongqiao WangXiaohui XieYingfei LiuXia WangHuanglingzi LiuBin WangZhen LiuYuezhong Tang
    • G06F3/048
    • G06F3/0488G06F1/1626G06F3/0482G06F2200/1637
    • An apparatus, a method, a computer program and a graphical user interface is provided. The apparatus comprises at least one processor; and at least one memory storing computer program instructions, the at least one processor being configured to execute the computer program instructions to cause the apparatus at least to perform: controlling a display to display one or more graphical items from a first layer of a hierarchical menu system; in response to user selection of a first graphical item from the first layer of the hierarchical menu system, entering a second layer of the hierarchical menu system, wherein entering the second layer of the hierarchical menu system comprises displaying one or more further graphical items, from the second layer of the hierarchical menu system, associated with the first graphical item; detecting a change in inclination of the apparatus, while the one or more graphical items from the first layer of the hierarchical menu system are displayed on the display; and controlling, after detecting the change in inclination of the apparatus, the display to display a preview comprising the one or more further graphical items, associated with the first graphical item, from the second layer of the hierarchical menu system.
    • 提供了一种装置,方法,计算机程序和图形用户界面。 该装置包括至少一个处理器; 以及至少一个存储计算机程序指令的存储器,所述至少一个处理器被配置为执行所述计算机程序指令以使所述设备至少执行:控制显示器以从分层菜单的第一层显示一个或多个图形项目 系统; 响应于来自分层菜单系统的第一层的用户选择第一图形项目,进入层级菜单系统的第二层,其中进入层级菜单系统的第二层包括显示一个或多个其他图形项目,从 与第一图形项目相关联的分级菜单系统的第二层; 在显示器上显示来自分层菜单系统的第一层的一个或多个图形项目,检测装置的倾斜度变化; 以及在检测到所述装置的倾斜度的变化之后,控制所述显示器,以从所述分级菜单系统的第二层显示包括与所述第一图形项目相关联的所述一个或多个另外的图形项目的预览。
    • 86. 发明申请
    • TRACEABLE RETINOID ACID FOR IMAGING, DISEASE PREVENTION AND THERAPY
    • 用于成像,疾病预防和治疗的可追踪的抗感染药
    • US20120244079A1
    • 2012-09-27
    • US13319012
    • 2010-05-06
    • Shi KeMichel MawadWei Wang
    • Shi KeMichel MawadWei Wang
    • C07D403/08A61K49/04A61K49/00
    • A61K49/0052A61K49/0032G01N33/5008G01N33/5014G01N33/5088G01N33/574G01N33/582G01N2800/56
    • The present invention provides nonradioactive NIR optical imaging agents based up on the structure of retinoid acid derivatives. The nonradioactive NIR optical imaging agent has been evaluated at the cellular level by confocal microscopy, and in vivo in a whole animal using a various xenograft models. The specific uptake of this agent in human cancer cells and multiple xenograft models demonstrate that nonradioactive near infrared dye labeled retinoid metabolites and/or analogs are useful for early stage cancer studies and diagnoses. Also, the present invention provides that nonradioactive near infrared dye labeled retinoid metabolites and/or analogs are useful for visualization of drug redistribution within the body which is useful in determining the optimal biological dose. Ultimately, the visualization data can be used as an analytical tool to reduce any systemic toxicity.
    • 本发明提供了基于类视黄酸衍生物结构的非放射性近红外光学成像剂。 已经通过共聚焦显微镜在细胞水平上评估了非放射性近红外光学成像剂,并且在使用各种异种移植模型的整个动物体内进行了评估。 该药物在人类癌细胞和多种异种移植物模型中的特异性摄取表明,非放射性近红外染料标记的类视黄醇代谢物和/或类似物可用于早期癌症研究和诊断。 此外,本发明提供非放射性近红外染料标记的类视黄醇代谢物和/或类似物可用于体内药物再分布的可视化,其可用于确定最佳生物剂量。 最终,可视化数据可用作分析工具,以减少任何全身毒性。