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81. 发明申请

US20060223821A1 Piperidinyl piperazine derivatives useful as inhibitors of chemokine receptors 失效
标题翻译：可用作趋化因子受体抑制剂的哌啶基哌嗪衍生物
公开(公告)号：US20060223821A1
公开(公告)日：2006-10-05
申请号：US11358520
申请日：2006-02-21
申请人： Tze-Ming Chan , Kathleen Cox , Wenqing Feng , Michael Miller , Daniel Weston , Stuart McCombie
发明人： Tze-Ming Chan , Kathleen Cox , Wenqing Feng , Michael Miller , Daniel Weston , Stuart McCombie
IPC分类号： A61K31/496 , C07D403/14
CPC分类号： C07D211/96 , C07D401/06 , C07D401/14
摘要： In its many embodiments, the present invention provides a novel class of compounds of structural formula IA or IB where R1-R8 are as disclosed herein as inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
摘要翻译：在其许多实施方案中，本发明提供了一类新颖结构式IA或IB的化合物，其中R 1至R 8如本文所公开的CCR5受体的抑制剂制备这些化合物的方法，含有一种或多种这样的化合物的药物组合物，制备包含一种或多种这类化合物的药物制剂的方法，以及使用这种化合物治疗，预防，抑制或改善与CCR5相关的一种或多种疾病的方法或药物组合物。本发明还涉及本发明化合物与一种或多种可用于治疗人类免疫缺陷病毒（HIV）的抗病毒剂或其它药剂的组合的用途。本发明还涉及本发明化合物单独或与另一种药剂组合用于治疗实体器官移植排斥，移植物抗宿主病，关节炎，类风湿性关节炎，炎症性肠病，特应性皮炎，牛皮癣，哮喘，过敏或多发性硬化。

82. 发明申请

US20060219144A1 Telescoping mast having variable height locking and a chain erection mechanism with a cable management system 有权
公开(公告)号：US20060219144A1
公开(公告)日：2006-10-05
申请号：US11336265
申请日：2006-01-20
申请人： Michael Phelan , Michael Miller , Tom Ellington
发明人： Michael Phelan , Michael Miller , Tom Ellington
IPC分类号： B63B15/00
CPC分类号： B66F13/005 , B66F3/06 , F16G13/20 , Y10S254/06
摘要： A telescoping mast for supporting and raising a load may be telescopically extended by a zipper-action chain extension system further comprising a system for the management of one or more cables, such as power or communication cables traversing the length of the mast, and is capable of being locked into a rigid formation along a range of telescopic lengths.

83. 发明申请

US20060201948A1 Fluid containers with reservoirs in their closures and methods of use 有权
标题翻译：在其封闭件中具有储存器的流体容器和使用方法
公开(公告)号：US20060201948A1
公开(公告)日：2006-09-14
申请号：US11077630
申请日：2005-03-10
申请人： Richard Ellson , Michael Miller , Arlen Bramwell
发明人： Richard Ellson , Michael Miller , Arlen Bramwell
IPC分类号： B65D25/04
CPC分类号： B01L3/50853 , B01L3/50855 , B01L2200/142 , B01L2300/0829 , B01L2300/10 , G01N2035/00455 , Y10T436/25
摘要： Fluid containers are disclosed which have fluid reservoirs in their closures. These reservoirs are advantageous to hold sacrificial fluid which lessens the loss of the fluid of interest to the outside through evaporation. The reservoirs may have openings to the inside or outside of the container, or to both. Reservoirs with openings to the outside serve to reduce evaporative loss by raising the partial pressure of fluid in the vicinity of the contact between the closure and the remainder of the container. The reservoirs may be refillable without opening the container. In one embodiment a fluid reservoir allows the zone of contact between the closure and the remainder of the container to be immersed in fluid, so that gases seeking to escape the interior of the container must pass through fluid.
摘要翻译：公开了在其封闭件中具有流体储存器的流体容器。这些储存器有利于保持牺牲流体，其通过蒸发减少感兴趣的流体的损失。储存器可以具有到容器的内部或外部的开口，或者具有到两者的开口。具有向外部开口的容器用于通过提高封闭件和容器的其余部分之间的接触附近的流体的分压来减少蒸发损失。储存器可以在不打开容器的情况下重新填充。在一个实施例中，流体储存器允许封闭件和容器的其余部分之间的接触区浸没在流体中，使得试图逃离容器内部的气体必须通过流体。

84. 发明申请

US20060152524A1 Four color digital cinema system with extended color gamut and copy protection 有权
标题翻译：四色数字影院系统具有扩展的色域和复制保护
公开(公告)号：US20060152524A1
公开(公告)日：2006-07-13
申请号：US11033782
申请日：2005-01-12
申请人： Michael Miller , Michael Murdoch , Thomas Madden
发明人： Michael Miller , Michael Murdoch , Thomas Madden
IPC分类号： G09G5/02
CPC分类号： G11B20/00086 , G06T1/0028 , G06T2201/0064 , G11B20/00826 , G11B20/00884 , H04N5/913 , H04N9/3173 , H04N9/3182 , H04N9/3194 , H04N9/67 , H04N2005/91392
摘要： A color display system including a display device for four or more visible color primaries and a processor for controlling the four or more color primaries to selectively render portions of an image or image sequence such that visually equivalent colors displayed in two or more image portions differ in their spectral composition.
摘要翻译：一种彩色显示系统，包括用于四个或更多可见颜色原色的显示装置和一个用于控制四个或更多个颜色原色以选择性地渲染图像或图像序列的部分的处理器，使得在两个或更多图像部分中显示的视觉上相当的颜色不同它们的光谱组成。

85. 发明授权

US07064542B2 Hybrid Hall vector magnetometer 失效
标题翻译：混合霍尔矢量磁强计
公开(公告)号：US07064542B2
公开(公告)日：2006-06-20
申请号：US11172663
申请日：2005-07-01
申请人： Mark B. Johnson , Michael Miller , Brian Bennett
发明人： Mark B. Johnson , Michael Miller , Brian Bennett
IPC分类号： G01R33/07
CPC分类号： G01R33/07 , Y10S977/853 , Y10S977/865
摘要： A modified hybrid Hall effect device is provided which is the combination of a conventional Hall effect device and a second Hall effect device having a Hall plate coupled to a ferromagnetic layer. The hybrid Hall effect device can be used to determine the independent magnetic field vector components comprising a vector magnetic field, such as for determining the x and the z components of a magnetic field, or for measuring the total magnitude of a vector magnetic field of any orientation. The modified Hall Effect device can be adapted for use as a magnetic field sensor for the detection of macroscopic objects that have associated magnetic fields, or for microscopic objects that have been tagged by microscopic magnetic particles. In one specific form, a plurality of hybrid Hall devices are electrically connected together to form an array in which a plurality of rows of hybrid Hall devices are electrically coupled to each other along a current axis, and the array is used for the detection of microscopic objects.
摘要翻译：提供了一种改进的混合霍尔效应装置，它是常规霍尔效应装置和具有耦合到铁磁层的霍尔板的第二霍尔效应装置的组合。可以使用混合霍尔效应装置来确定包括矢量磁场的独立磁场矢量分量，例如用于确定磁场的x和z分量，或用于测量任意的矢量磁场的总大小方向。修改的霍尔效应装置可以适用于用于检测具有相关磁场的宏观物体的磁场传感器，或用于由微观磁性颗粒标记的微观物体。在一个具体形式中，多个混合霍尔器件电连接在一起以形成阵列，其中多行混合霍尔器件沿着电流轴彼此电耦合，并且该阵列用于微观检测对象

86. 发明申请

US20060111454A1 Composition to reduce adhesion between a conformable region and a mold 有权
标题翻译：组合物以减少适形区域和模具之间的粘附
公开(公告)号：US20060111454A1
公开(公告)日：2006-05-25
申请号：US11068171
申请日：2005-02-28
申请人： Frank Xu , Michael Miller
发明人： Frank Xu , Michael Miller
IPC分类号： B01F17/00 , B01F3/08
CPC分类号： G03F7/0002 , B82Y10/00 , B82Y40/00
摘要： The present invention provides compositions that feature improved preferential adhesion and release characteristics with respect to a substrate and a mold having imprinting material disposed therebetween. To that end, the compositions facilitate bifurcation of the imprinting into a surfactant-component-rich sub-portion and a surfactant-component-depleted sub-portion located between said surfactant-component-rich sub-portion and said substrate. This surfactant-component-rich sub-portion attenuates the adhesion forces between the mold and the imprinting material, once solidified.
摘要翻译：本发明提供了相对于基底和具有设置在其间的压印材料的模具具有改进的优先粘附和释放特性的组合物。为此，组合物有利于将压印物分成富含表面活性剂组分的亚部分和位于所述富表面活性剂组分的子部分和所述底物之间的表面活性剂组分贫乏的子部分。该表面活性剂成分丰富的子部分一旦固化，就会使模具和压印材料之间的粘合力衰减。

87. 发明授权

US06997134B2 Drum breader and coating redistribution system 失效
标题翻译：鼓面包机和涂层再分配系统
公开(公告)号：US06997134B2
公开(公告)日：2006-02-14
申请号：US10359023
申请日：2003-02-05
申请人： Robert Phillip Bayus , David Alan Bailey , Ramesh M. Gunawardena , Michael Miller , Harold Eugene Patterson
发明人： Robert Phillip Bayus , David Alan Bailey , Ramesh M. Gunawardena , Michael Miller , Harold Eugene Patterson
IPC分类号： B05C19/06
CPC分类号： A23G3/0095 , A23G3/0085 , A23G3/0089 , A23L13/57 , A23P20/13
摘要： A drum breader and coating recirculation system that includes a spreader positioned at an end of the drum, the spreader having a plurality of angled surfaces to distribute coatings evenly; a screening platform positioned downstream of the spreader having a drive device for imparting straight-line angular displacement to the screening platform; and a drum feed conveyor positioned downstream of the screening platform, the drum feed conveyor having a belt extending at least partially along an upward angle.
摘要翻译：鼓面包机和涂层再循环系统，其包括位于滚筒末端的撒布机，撒布机具有多个成角度的表面以均匀地分布涂层; 位于撒布机下游的筛选平台具有用于向筛选平台施加直线角位移的驱动装置; 以及位于所述筛选平台下游的滚筒进料输送机，所述滚筒进料输送机具有至少部分地沿着向上的角度延伸的带。

88. 发明申请

US20060030784A1 Collection filter 审中-公开
标题翻译：收集过滤器
公开(公告)号：US20060030784A1
公开(公告)日：2006-02-09
申请号：US11247707
申请日：2005-10-11
申请人： Michael Miller , Joseph Mark
发明人： Michael Miller , Joseph Mark
IPC分类号： A61B10/00
CPC分类号： A61B10/025 , A61B10/0283 , A61B17/3498 , A61B2010/0208 , A61B2017/00973 , A61B2217/005 , A61B2217/007
摘要： A filter element is provided for use with a tissue cutting device. The tissue cutting device includes a tissue collection trap in which the filter element is mounted. The filter element includes a body formed of a mesh material. The mesh material is constructed to allow for fluids to pass through a portion of the filter element while tissue samples excised by the cutting device are retained therein.
摘要翻译：提供了一种与组织切割装置一起使用的过滤元件。组织切割装置包括其中安装有过滤元件的组织收集阱。过滤元件包括由网状材料形成的主体。网状材料被构造成允许流体通过过滤元件的一部分，而由切割装置切除的组织样品保持在其中。

89. 发明申请

US20060025441A1 Bipiperidinyl derivatives useful as inhibitors of chemokine receptors 失效
标题翻译：可用作趋化因子受体抑制剂的二哌啶基衍生物
公开(公告)号：US20060025441A1
公开(公告)日：2006-02-02
申请号：US10979075
申请日：2004-11-01
申请人： Michael Miller , Jack Scott
发明人： Michael Miller , Jack Scott
IPC分类号： A61K31/4545 , C07D401/04
CPC分类号： C07D413/14 , C07D401/14
摘要： In its many embodiments, the present invention provides a novel class of bipiperidinyl compounds as inhibitors of the CCR5 receptors, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with CCR5 using such compounds or pharmaceutical compositions. The invention also relates to the use of a combination of a compound of this invention and one or more antiviral or other agents useful in the treatment of Human Immunodeficiency Virus (HIV). The invention further relates to the use of a compound of this invention, alone or in combination with another agent, in the treatment of solid organ transplant rejection, graft v. host disease, arthritis, rheumatoid arthritis, inflammatory bowel disease, atopic dermatitis, psoriasis, asthma, allergies or multiple sclerosis.
摘要翻译：在其许多实施方案中，本发明提供了作为CCR5受体的抑制剂的新类型的联哌啶化合物，制备这些化合物的方法，含有一种或多种这样的化合物的药物组合物，制备包含一种或多种这样的化合物的药物制剂的方法，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CCR5相关的一种或多种疾病的方法。本发明还涉及本发明化合物与一种或多种可用于治疗人类免疫缺陷病毒（HIV）的抗病毒剂或其它药剂的组合的用途。本发明还涉及本发明化合物单独或与另一种药剂组合用于治疗实体器官移植排斥，移植物抗宿主病，关节炎，类风湿性关节炎，炎症性肠病，特应性皮炎，牛皮癣，哮喘，过敏或多发性硬化。

90. 发明申请

US20050270444A1 Color display device with enhanced pixel pattern 有权
标题翻译：具有增强像素图案的彩色显示设备
公开(公告)号：US20050270444A1
公开(公告)日：2005-12-08
申请号：US10859314
申请日：2004-06-02
申请人： Michael Miller , Michael Murdoch , Paul Kane , Andrew Arnold , Serguei Endrikhovski
发明人： Michael Miller , Michael Murdoch , Paul Kane , Andrew Arnold , Serguei Endrikhovski
IPC分类号： G09G3/20 , G09G3/32 , G09G3/36 , G09G5/02 , G02F1/1335
CPC分类号： G09G3/3216 , G09G3/20 , G09G3/3225 , G09G3/3607 , G09G5/02 , G09G2300/0452 , G09G2320/02
摘要： A color display device, comprising: an array of subpixels of at least four different colors, including at least two relatively higher luminous color subpixels and at least two relatively lower luminous color subpixels, wherein the subpixels are arranged into groups forming at least two distinct types of pixels, each pixel type including the two relatively higher luminous color subpixels and at least one of the two relatively lower luminous color subpixels, and wherein the pixel types are arranged in a pattern such that the relative locations of the two relatively higher luminous color subpixels in each pixel is repeated in adjacent pixels, and the relative location of at least one of the two relatively lower luminance color subpixels is not repeated in at least one adjacent pixel. Various embodiments of the invention enable color display devices with improved image display quality, with both the appearance of jagged lines and the appearance of banding reduced simultaneously.
摘要翻译：一种彩色显示装置，包括：至少四种不同颜色的子像素阵列，包括至少两个相对较高的发光子像素和至少两个相对较低的发光颜色子像素，其中子像素被排列成形成至少两种不同类型的组的像素，每个像素类型包括两个相对较高的发光颜色子像素和两个相对较低的发光颜色子像素中的至少一个，并且其中像素类型被布置成使得两个相对较高的发光颜色子像素的相对位置在相邻像素中重复每个像素，并且在至少一个相邻像素中不重复两个相对较低亮度的彩色子像素中的至少一个的相对位置。本发明的各种实施例使得具有改善的图像显示质量的彩色显示设备能够同时缩短锯齿状线条的外观和条纹的外观。

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