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81. 发明授权

US6024703A Ultrasound device for axial ranging 失效
公开(公告)号：US6024703A
公开(公告)日：2000-02-15
申请号：US852977
申请日：1997-05-07
申请人： Claudio I. Zanelli , Jeffrey J. Giba , Michael A. Davis , Douglas Murphy-Chutorian
发明人： Claudio I. Zanelli , Jeffrey J. Giba , Michael A. Davis , Douglas Murphy-Chutorian
IPC分类号： A61B17/00 , A61B17/22 , A61B18/20 , A61B18/24 , A61B8/00
CPC分类号： A61B18/20 , A61B18/24 , A61B2017/00106 , A61B2017/00247 , A61B2017/22072 , A61B2018/00392 , A61B2018/00636
摘要： A treatment tool such as a catheter, MIS or other surgical tool apparatus for placement within a heart chamber, organ aperture or other body opening and axial ranging therein, the apparatus particularly adapted for laser-assisted percutaneous transmyocardial revascularization (MTR). At the distal end of the tool is an annular ultrasound transducer with associated structure, positioned to transmit ultrasound signals substantially axially aligned with the axis of the treatment tool to the cardiovascular tissue, the transducer further receiving returning signals from the cardiovascular tissue to be treated. In a preferred embodiment, the transducer comprises a piezoelectric crystal material. The transducer assembly is attached to the distal tip of the tool such that a laser delivery means or other functional device can be extended through the lumen of the tool and the annular ultrasound transducer. In a preferred embodiment, the invention is a modular ultrasound device capable of being detachably attached to a steerable catheter, MIS or other surgical tool apparatus. The system also comprises a signal interface extending from the ultrasound transducer and signal processing component operatively connected to the signal interface for real time determination of at least one boundary surface of cardiovascular tissue relative to one or more positions of the distal tip of the treatment tool. A method of delivering laser energy to tissue is disclosed, the method including the steps of positioning the firing tip of a laser delivery means adjacent the front surface of the tissue, delivering laser energy to the tissue, transmitting ultrasound energy to the tissue, receiving ultrasound signals reflected from at least the rear surface of the tissue, and determining the distance betwveen the firing tip of the laser delivery means and the rear surface of the tissue. In a preferred embodiment, the method includes quantitative determination of the contractility or motion of the beating heart, such that changes in the depth of tissue can be used to control the channel depth or other treatment parameters. Retrolasing can also be achieved by mechanically piercing the tissue to a determined depth based on axial ranging measurements, and retracting the treatment tool while simultaneously delivering laser energy therefrom.

82. 发明授权

US5739109A Method of treating neuroinflammatory degenerative diseases 失效
标题翻译：治疗神经炎症性退行性疾病的方法
公开(公告)号：US5739109A
公开(公告)日：1998-04-14
申请号：US608434
申请日：1996-02-28
申请人： Jeffrey E. Galpin , Dennis A. Casciato , Michael A. Davis , Saul M. Levin , MerriBeth Adams , Candace B. Pert , Michael R. Ruff , Gary Globe
发明人： Jeffrey E. Galpin , Dennis A. Casciato , Michael A. Davis , Saul M. Levin , MerriBeth Adams , Candace B. Pert , Michael R. Ruff , Gary Globe
IPC分类号： A61K38/08 , A61K38/16 , A61K38/07
CPC分类号： A61K38/08 , A61K38/162
摘要： The present invention relates to a method of treating neuroinflammatory degenerative diseases which are cytokine mediated. The method involves administration of an effective amount of Peptide T or a related Peptide to diminish, halt or reverse the patient's loss of function due to neuroinflammation.
摘要翻译：本发明涉及治疗神经炎症性退行性疾病的方法，其是细胞因子介导的。该方法包括施用有效量的肽T或相关肽以减少，停止或逆转患者由于神经炎症引起的功能丧失。

83. 发明授权

US4490431A 0.1 Micron rated polypropylene membrane and method for its preparation 失效
标题翻译： 0.1微米级聚丙烯膜及其制备方法
公开(公告)号：US4490431A
公开(公告)日：1984-12-25
申请号：US438823
申请日：1982-11-03
申请人： Gunter H. Vitzthum , Michael A. Davis
发明人： Gunter H. Vitzthum , Michael A. Davis
IPC分类号： B01D67/00 , B01D69/02 , B01D71/26 , C08J9/00 , C08J9/28 , B32B3/00 , B29D27/04
CPC分类号： C08J9/28 , B01D67/003 , B01D69/02 , B01D71/26 , C08J2201/03 , C08J2201/052 , C08J2201/0542 , C08J2323/12 , Y10T428/249979
摘要： There is disclosed a substantially skinless microporous polypropylene membrane characterized by having(a) a bubble point of about 25 to about 50 psi;(b) a thickness of about 3 to about 7 mils;(c) a nitrogen flow rate of at least 0.5 liters per square centimeter-minute;(d) a burst strength of at least 10 psi; and(e) an S value of about 15, or less.There is also disclosed a method of preparing a microporous polypropylene membrane comprising heating a mixture of about 30 percent polypropylene and about 70 percent, N,N-bis(2-hydroxyethyl)tallowamine, by weight, to a temperature and for a time sufficient to form a homogeneous solution, casting or extruding said solution at a thickness of about 3 to about 7 mils, onto a chill roll maintained at a temperature of from about 50.degree. to about 80.degree. C., allowing said solution to solidify on said chill roll to form a solid sheet, removing said solid sheet from said chill roll and removing at least a substantial portion of the liquid from said sheet to form the microporous polypropylene membrane.
摘要翻译：公开了一种基本上无皮的微孔聚丙烯膜，其特征在于具有（a）约25至约50psi的起泡点; （b）约3至约7密耳的厚度; （c）至少0.5升/平方厘米分钟的氮气流量; （d）至少10psi的爆裂强度; 和（e）约15或更小的S值。还公开了一种制备微孔聚丙烯膜的方法，其包括将约30％聚丙烯和约70％重量的N，N-双（2-羟乙基）牛油胺的混合物加热到足以使形成均匀的溶液，将所述溶液以约3至约7密耳的厚度浇铸或挤出到保持在约50℃至约80℃温度的冷却辊上，使所述溶液在所述冷却辊上固化以形成固体片材，从所述冷却辊中除去所述固体片材并从所述片材中除去至少大部分的液体以形成微孔聚丙烯膜。

84. 发明授权

US09297733B2 Dispersion compensation technique for differential sonar measurement—density meter 有权
标题翻译：差分声纳测量密度计的色散补偿技术
公开(公告)号：US09297733B2
公开(公告)日：2016-03-29
申请号：US13583274
申请日：2011-03-09
申请人： Michael A. Davis
发明人： Michael A. Davis
IPC分类号： G01N9/24 , G01F1/66 , G01N9/00 , G01N11/00
CPC分类号： G01N9/24 , G01F1/663 , G01N9/00 , G01N2011/0073
摘要： The present invention provides a novel technique for canceling substantially the effects of dispersion when two speed of sound (SOS) measurements are required on the materials within a pipe to perform a calculation or derive certain characteristics about the materials flowing in the pipe. According to some embodiments of the present invention, the apparatus may comprise a signal processor configured to receive signals containing information about two speed of sound measurements having two sets of data related to materials within a pipe; and process the two sets of data simultaneously and determine a ridge point by point difference in order to cancel substantially effects of dispersion.
摘要翻译：本发明提供了一种新颖的技术，用于在管道内的材料上需要两个声速（SOS）测量值时，实质上消除色散的影响，以进行计算或得出关于在管道中流动的材料的某些特性。根据本发明的一些实施例，所述装置可以包括信号处理器，其被配置为接收包含关于具有与组件内的材料相关的两组数据的两个声速测量速度的信息的信号; 并且同时处理这两组数据，并确定一个点的点差，以便基本上消除色散的影响。

85. 发明授权

US07752918B2 Apparatus and method for measuring a fluid flow parameter within an internal passage of an elongated body 有权
标题翻译：用于测量细长体的内部通道内的流体流动参数的装置和方法
公开(公告)号：US07752918B2
公开(公告)日：2010-07-13
申请号：US11937003
申请日：2007-11-08
申请人： Michael A. Davis
发明人： Michael A. Davis
IPC分类号： G01F1/20 , G01F1/66
CPC分类号： G01F1/7082 , G01F1/667 , G01F1/712 , G01F1/74
摘要： A method and apparatus for measuring at least one parameter of a fluid flowing through an internal passage of an elongated body is provided. The internal passage is disposed between a first wall and a second wall, and the first wall and the second wall each include an interior surface and an exterior surface. The method includes the steps of providing an array of at least two ultrasonic sensor units, operating the sensor units to transmit ultrasonic signals at one or more frequencies substantially coincident with at least one frequency at which the transmitted ultrasonic signals resonate within the first wall, receiving the ultrasonic signals with the sensor units, and processing the received ultrasonic signals to measure the at least one parameter of fluid flow within the internal passage.
摘要翻译：提供一种用于测量流过细长体的内部通道的流体的至少一个参数的方法和装置。内部通道设置在第一壁和第二壁之间，并且第一壁和第二壁各自包括内表面和外表面。所述方法包括以下步骤：提供至少两个超声波传感器单元的阵列，操作所述传感器单元以一个或多个频率发射超声波信号，所述超声波信号基本上与所述发射的超声波信号在所述第一壁内谐振的至少一个频率重合，接收所述超声波信号与所述传感器单元相关联，并且处理所接收的超声波信号以测量所述内部通道内的流体流动的所述至少一个参数。

86. 发明申请

US20080173100A1 Apparatus And Method For Measuring A Fluid Flow Parameter Within An Internal Passage Of An Elongated Body 有权
标题翻译：用于测量伸长体内部通道内流体流动参数的装置和方法
公开(公告)号：US20080173100A1
公开(公告)日：2008-07-24
申请号：US11937003
申请日：2007-11-08
申请人： Michael A. Davis
发明人： Michael A. Davis
IPC分类号： G01F1/66
CPC分类号： G01F1/7082 , G01F1/667 , G01F1/712 , G01F1/74
摘要： A method and apparatus for measuring at least one parameter of a fluid flowing through an internal passage of an elongated body is provided. The internal passage is disposed between a first wall and a second wall, and the first wall and the second wall each include an interior surface and an exterior surface. The method includes the steps of providing an array Of at least two ultrasonic sensor units, operating the sensor units to transmit ultrasonic signals at one or more frequencies substantially coincident with at least one frequency at which the transmitted ultrasonic signals resonate within the first wall, receiving the ultrasonic signals with the sensor units, and processing the received ultrasonic signals to measure the at least one parameter of fluid flow within the internal passage.
摘要翻译：提供一种用于测量流过细长体的内部通道的流体的至少一个参数的方法和装置。内部通道设置在第一壁和第二壁之间，并且第一壁和第二壁各自包括内表面和外表面。该方法包括以下步骤：提供至少两个超声波传感器单元的阵列，操作传感器单元以一个或多个频率发射超声波信号，该频率与至少一个发射的超声波信号在第一壁内共振的频率基本一致，接收所述超声波信号与所述传感器单元相关联，并且处理所接收的超声波信号以测量所述内部通道内的流体流动的所述至少一个参数。

87. 发明授权

US07322251B2 Method and apparatus for measuring a parameter of a high temperature fluid flowing within a pipe using an array of piezoelectric based flow sensors 有权
标题翻译：用于使用基于压电的流量传感器的阵列测量在管内流动的高温流体的参数的方法和装置
公开(公告)号：US07322251B2
公开(公告)日：2008-01-29
申请号：US10909612
申请日：2004-08-02
申请人： Daniel L. Gysling , Michael A. Davis , James R. Dunphy , Paul F. Croteau , Robert J. Maron
发明人： Daniel L. Gysling , Michael A. Davis , James R. Dunphy , Paul F. Croteau , Robert J. Maron
IPC分类号： G01F1/66
CPC分类号： G01F1/662 , G01F1/7082 , G01F1/712 , G01F1/74
摘要： A method, apparatus and system are provided to measure the process flow of a fluid or medium traveling in a pipe. The system and apparatus feature a standoff and piezoelectric-based sensor arrangement having a plurality of standoffs arranged on a pipe and a plurality of sensor bands, each arranged on a respective plurality of standoffs, each having at least one sensor made of piezoelectric material arranged thereon to detect unsteady pressure disturbances in the process flow in the pipe which in turn can be converted to the velocity of and/or speed of sound propagating within the pipe, and a cooling tube arranged in relation to the plurality of standoffs for actively cooling the sensor band; and further comprise a processing module for converting one or more sensor signals into a measurement containing information about the flow of the fluid or medium traveling in the pipe, as well as a pump and heat exchanger for processing the cooling fluid flowing through the cooling tube. The processing includes maintaining the cooling fluid at a desired operating temperature.
摘要翻译：提供了一种方法，装置和系统来测量在管道中行进的流体或介质的工艺流程。该系统和装置具有一个支座和基于压电的传感器装置，其具有布置在管道上的多个支座和多个传感器带，每个传感器带布置在相应的多个支座上，每个支架具有至少一个由压电材料制成的传感器以检测管道中的过程流动中的不稳定的压力扰动，其又可以转换成在管道内传播的声音的速度和/或速度，以及相对于多个支座布置的冷却管，用于主动冷却传感器带; 并且还包括用于将一个或多个传感器信号转换成包含关于在管道中流动的流体或介质的流动的信息的测量的处理模块，以及用于处理流过冷却管的冷却流体的泵和热交换器。该处理包括将冷却流体保持在期望的操作温度。

88. 发明授权

US06603326B1 Testing integrated circuits with integrated power transistors 有权
标题翻译：用集成功率晶体管测试集成电路
公开(公告)号：US06603326B1
公开(公告)日：2003-08-05
申请号：US09766231
申请日：2001-01-19
申请人： Lawrence T. Tse , Michael A. Davis , Anthony J. Stratakos
发明人： Lawrence T. Tse , Michael A. Davis , Anthony J. Stratakos
IPC分类号： G01R3140
CPC分类号： G01R31/40
摘要： A switching regulator that has first, second, third and fourth terminals, a first power transistor disposed between the first terminal and a first node, a second power transistor disposed between the first node and a second node, a filter including a capacitor and an inductor, and a controller. The first power transistor is partitioned into a plurality of individually-addressable first transistor segments. The second node couples the second and fourth terminals. The second power transistor is partitioned into a plurality of individually-addressable second transistor segments. The inductor is disposed between the first node and the third terminal, and the capacitor is disposed between the third and fourth terminals. The controller is operable in a plurality of modes including a normal mode in which the controller opens and closes all of the first transistor segments and all of the second transistor segments, and a test mode in which the controller opens and closes less than all of the first transistor segments and all of the second transistor segments.
摘要翻译：一种具有第一，第二，第三和第四端子的开关调节器，设置在第一端子和第一节点之间的第一功率晶体管，设置在第一节点和第二节点之间的第二功率晶体管，包括电容器和电感器的滤波器，和控制器。第一功率晶体管被划分成多个可单独寻址的第一晶体管段。第二节点耦合第二和第四终端。第二功率晶体管被划分成多个单独寻址的第二晶体管段。电感器设置在第一节点和第三终端之间，电容器设置在第三和第四终端之间。控制器可以在多种模式中操作，包括其中控制器打开和关闭所有第一晶体管段和所有第二晶体管段的正常模式，以及控制器打开和关闭小于全部的测试模式第一晶体管段和所有第二晶体管段。

89. 外观设计

USD414076S Base for power-operated vegetable slicer 失效
公开(公告)号：USD414076S
公开(公告)日：1999-09-21
申请号：US87523
申请日：1998-05-04
申请人： Michael A. Davis , Christopher T. Troyer
设计人： Michael A. Davis , Christopher T. Troyer

90. 发明授权

US5807490A Method of separating polymers from mixtures thereof 失效
标题翻译：从其混合物中分离聚合物的方法
公开(公告)号：US5807490A
公开(公告)日：1998-09-15
申请号：US621637
申请日：1996-03-26
申请人： Michael A. Davis , Jeffrey S. Dugan , Matthew B. Hoyt , Charles F. Helms, Jr.
发明人： Michael A. Davis , Jeffrey S. Dugan , Matthew B. Hoyt , Charles F. Helms, Jr.
IPC分类号： B29B13/02 , B29B17/02 , B29C47/06 , C08F6/04 , B01D57/00
CPC分类号： D01D5/34 , B29B13/022 , B29B17/02 , B29C47/0016 , B29C47/0023 , B29C47/065 , B29C47/128 , B29C47/26 , C08F6/04 , B29B2017/0203 , B29K2023/06 , B29K2077/00 , B29K2105/06 , Y02W30/622
摘要： A method of separating two immiscible, melt-viscosity-differing thermoplastic polymer components from a mixed liquid stream thereof forms two discrete and continuous phases having a sheath/core configuration, wherein the sheath substantially contains the polymer component with the higher melt viscosity and the core substantially contains the polymer component with the lower melt viscosity. The mixed liquid stream contains a predominant amount (i.e., greater than 50% by volume) of the higher viscosity polymer component and a minority amount (i.e., less than 50% by volume) of the lower viscosity polymer component. The method involves directing the stream through a shear zone at a shear temperature and a shear rate sufficient to form the two discrete and continuous phases, the first of which substantially contains the lower viscosity polymer component and the second of which substantially contains the higher viscosity polymer component.
摘要翻译：从混合液体流中分离出两种不混溶的，熔融不粘的不同的热塑性聚合物组分的方法形成具有鞘/芯构型的两个离散且连续的相，其中护套基本上含有具有较高熔体粘度的聚合物组分和核基本上含有熔体粘度较低的聚合物组分。混合液体流含有较高粘度聚合物组分的主要量（即大于50体积％）和较低粘度聚合物组分的少量（即少于50体积％）。该方法包括在剪切温度和剪切速率下将流引导通过剪切带，其剪切速率足以形成两个离散和连续的相，其中第一个相基本上包含较低粘度的聚合物组分，其中第二个基本上含有较高粘度的聚合物零件。

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