专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08187251B2 Methods of treating cardiac arrhythmia 有权
标题翻译：治疗心律失常的方法
公开(公告)号：US08187251B2
公开(公告)日：2012-05-29
申请号：US11591126
申请日：2006-10-31
申请人： U. Hiram Chee , Richard L. Mueller , James R. Kermode , Curtis P. Tom , Douglas Murphy-Chutorian
发明人： U. Hiram Chee , Richard L. Mueller , James R. Kermode , Curtis P. Tom , Douglas Murphy-Chutorian
IPC分类号： A61M31/00
CPC分类号： A61B17/32037 , A61B17/282 , A61B17/3207 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/22077 , A61B2018/00392 , A61B2018/00839 , A61B2018/00875 , A61B2018/1425 , A61B2090/064 , A61B2090/067 , A61B2218/002 , A61M5/30 , A61M37/0092 , A61M2025/0089
摘要： Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.
摘要翻译：本发明的实施例的方法和装置适于治疗患者体内的组织。本发明的各方面可以用于各种各样的应用中，但是某些实施方案提供了通过将组织损伤剂输送到心脏的选定区域来治疗心房颤动的微创替代方案。本发明的一个示例性实施方案提供了治疗心律失常的方法。该方法包括将身体的远端组织接触部分定位成与心脏组织的组织表面表面接触; 检测组织接触部分和组织表面之间的表面接触; 然后通过身体的组织接触部分将组织消融剂注入心脏组织。

2. 发明授权

US06620153B2 Intraoperative myocardial device and stimulation procedure 失效
标题翻译：术中心肌装置及刺激程序
公开(公告)号：US06620153B2
公开(公告)日：2003-09-16
申请号：US09854072
申请日：2001-05-11
申请人： Richard L. Mueller , Douglas Murphy-Chutorian , Stuart D. Harman
发明人： Richard L. Mueller , Douglas Murphy-Chutorian , Stuart D. Harman
IPC分类号： A61G1820
CPC分类号： A61B18/24 , A61B2017/00172 , A61B2017/00247 , A61B2017/22074 , A61B2017/22077 , A61B2018/00392 , A61B2018/208
摘要： An apparatus for stimulating revascularization of myocardium tissue in the ventricular wall of a human heart is disclosed. The apparatus includes means for moving the distal end of an optical fiber element forwardly through the epicardium of the heart and into the myocardium and emitting relatively low power bursts of laser energy from the distal end to form stimulus injury zones that promote capillary growth and tissue revascularization. Each penetration of the optical fiber element may produce multiple stimulus zones spaced radially from or in line with the axis of the optical fiber element. Apparatus for moving the optical fiber element and controlling the laser emissions in a predetermined manner is also disclosed.
摘要翻译：公开了一种用于刺激人心脏心室壁心肌组织血运重建的装置。该装置包括用于将光纤元件的远端向前移动通过心脏心外膜并进入心肌的装置，并且从远端发射相对低功率的激光能量脉冲以形成促进毛细血管生长和组织血运重建的刺激性损伤区域。光纤元件的每次穿透可以产生与光纤元件的轴线径向间隔开或与光纤元件的轴线成间隔的多个刺激区域。还公开了用于移动光纤元件并以预定方式控制激光发射的装置。

3. 发明授权

US5999678A Laser delivery means adapted for drug delivery 失效
标题翻译：用于药物输送的激光输送装置
公开(公告)号：US5999678A
公开(公告)日：1999-12-07
申请号：US773430
申请日：1996-12-27
申请人： Douglas Murphy-Chutorian , Richard L. Mueller , Stuart D. Harman , Steve A. Daniel , Larry Witham , Bruce Richardson
发明人： Douglas Murphy-Chutorian , Richard L. Mueller , Stuart D. Harman , Steve A. Daniel , Larry Witham , Bruce Richardson
IPC分类号： A61B17/00 , A61B18/24 , G02B6/06 , A61B17/36 , A61M31/00
CPC分类号： A61B18/24 , A61B2017/00247 , A61B2018/00392
摘要： A drug delivery apparatus for dispensing a predetermined amount of one or more drugs into a laser created opening in the human body, the apparatus consisting of a laser delivery means such as an optical fiber or fiber bundle, a drug conduit which transfers the one or more drugs, drug solutions or other substances to the distal end of the laser delivery means, and the laser delivery means disposed essentially coaxially with the drug conduit. Laser delivery means is used to create a TMR channel or other opening in the body. Dispensed drug or other substance travels through the drug conduit and emanates from the drug conduit to be delivered into the TMR channel or other laser created opening. Drug is dispensed by manually or automatically activating an electric motor which actuates a piston element. A method of use is also disclosed.
摘要翻译：一种用于将预定量的一种或多种药物分配到人体内的激光产生开口中的药物输送装置，该装置由诸如光纤或纤维束的激光输送装置组成，药物导管将一个或多个药物，药物溶液或其它物质，并且激光输送装置基本上与药物导管同轴地设置。激光输送装置用于在体内产生TMR通道或其他开口。分配的药物或其他物质通过药物导管，并从药物导管发出，以被输送到TMR通道或其他激光产生的开口中。药物通过手动或自动激活致动活塞元件的电动机来分配。还公开了一种使用方法。

4. 发明申请

US20120238996A1 METHODS OF TREATING CARDIAC ARRHYTHMIA 审中-公开
标题翻译：治疗心脑血管病的方法
公开(公告)号：US20120238996A1
公开(公告)日：2012-09-20
申请号：US13481251
申请日：2012-05-25
申请人： U. Hiram Chee , Richard L. Mueller , James R. Kermode , Curtis P. Tom , Douglas Murphy-Chutorian
发明人： U. Hiram Chee , Richard L. Mueller , James R. Kermode , Curtis P. Tom , Douglas Murphy-Chutorian
IPC分类号： A61M37/00
CPC分类号： A61B17/32037 , A61B17/282 , A61B17/3207 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/22077 , A61B2018/00392 , A61B2018/00839 , A61B2018/00875 , A61B2018/1425 , A61B2090/064 , A61B2090/067 , A61B2218/002 , A61M5/30 , A61M37/0092 , A61M2025/0089
摘要： Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.
摘要翻译：本发明的实施例的方法和装置适于治疗患者体内的组织。本发明的各方面可以用于各种各样的应用中，但是某些实施方案提供了通过将组织损伤剂输送到心脏的选定区域来治疗心房颤动的微创替代方案。本发明的一个示例性实施方案提供了治疗心律失常的方法。该方法包括将身体的远端组织接触部分定位成与心脏组织的组织表面表面接触; 检测组织接触部分和组织表面之间的表面接触; 然后通过身体的组织接触部分将组织消融剂注入心脏组织。

5. 发明申请

US20070055230A1 Methods of treating cardiac arrhythmia 有权
标题翻译：治疗心律失常的方法
公开(公告)号：US20070055230A1
公开(公告)日：2007-03-08
申请号：US11591126
申请日：2006-10-31
申请人： U. Chee , Richard Mueller , James Kermode , Curtis Tom , Douglas Murphy-Chutorian
发明人： U. Chee , Richard Mueller , James Kermode , Curtis Tom , Douglas Murphy-Chutorian
IPC分类号： A61B18/14
CPC分类号： A61B17/32037 , A61B17/282 , A61B17/3207 , A61B34/20 , A61B2017/00243 , A61B2017/00247 , A61B2017/22077 , A61B2018/00392 , A61B2018/00839 , A61B2018/00875 , A61B2018/1425 , A61B2090/064 , A61B2090/067 , A61B2218/002 , A61M5/30 , A61M37/0092 , A61M2025/0089
摘要： Methods and apparatus of embodiments of the invention are adapted to treat tissue inside a patient's body. Aspects of the invention can be used in a wide variety of applications, but certain embodiments provide minimally invasive alternatives for treating atrial fibrillation by delivering a tissue-damaging agent to selected areas of the heart. One exemplary embodiment of the invention provides a method of treating cardiac arrhythmia. This method includes positioning a distal tissue-contacting portion of a body in surface contact with a tissue surface of cardiac tissue; detecting the surface contact between the tissue-contacting portion and the tissue surface; and thereafter, injecting a tissue-ablating agent into the cardiac tissue through the tissue-contacting portion of the body.
摘要翻译：本发明的实施例的方法和装置适于治疗患者体内的组织。本发明的各方面可以用于各种各样的应用中，但是某些实施方案提供了通过将组织损伤剂输送到心脏的选定区域来治疗心房颤动的微创替代方案。本发明的一个示例性实施方案提供了治疗心律失常的方法。该方法包括将身体的远端组织接触部分定位成与心脏组织的组织表面表面接触; 检测组织接触部分和组织表面之间的表面接触; 然后通过身体的组织接触部分将组织消融剂注入心脏组织。

6. 发明授权

US6024703A Ultrasound device for axial ranging 失效
公开(公告)号：US6024703A
公开(公告)日：2000-02-15
申请号：US852977
申请日：1997-05-07
申请人： Claudio I. Zanelli , Jeffrey J. Giba , Michael A. Davis , Douglas Murphy-Chutorian
发明人： Claudio I. Zanelli , Jeffrey J. Giba , Michael A. Davis , Douglas Murphy-Chutorian
IPC分类号： A61B17/00 , A61B17/22 , A61B18/20 , A61B18/24 , A61B8/00
CPC分类号： A61B18/20 , A61B18/24 , A61B2017/00106 , A61B2017/00247 , A61B2017/22072 , A61B2018/00392 , A61B2018/00636
摘要： A treatment tool such as a catheter, MIS or other surgical tool apparatus for placement within a heart chamber, organ aperture or other body opening and axial ranging therein, the apparatus particularly adapted for laser-assisted percutaneous transmyocardial revascularization (MTR). At the distal end of the tool is an annular ultrasound transducer with associated structure, positioned to transmit ultrasound signals substantially axially aligned with the axis of the treatment tool to the cardiovascular tissue, the transducer further receiving returning signals from the cardiovascular tissue to be treated. In a preferred embodiment, the transducer comprises a piezoelectric crystal material. The transducer assembly is attached to the distal tip of the tool such that a laser delivery means or other functional device can be extended through the lumen of the tool and the annular ultrasound transducer. In a preferred embodiment, the invention is a modular ultrasound device capable of being detachably attached to a steerable catheter, MIS or other surgical tool apparatus. The system also comprises a signal interface extending from the ultrasound transducer and signal processing component operatively connected to the signal interface for real time determination of at least one boundary surface of cardiovascular tissue relative to one or more positions of the distal tip of the treatment tool. A method of delivering laser energy to tissue is disclosed, the method including the steps of positioning the firing tip of a laser delivery means adjacent the front surface of the tissue, delivering laser energy to the tissue, transmitting ultrasound energy to the tissue, receiving ultrasound signals reflected from at least the rear surface of the tissue, and determining the distance betwveen the firing tip of the laser delivery means and the rear surface of the tissue. In a preferred embodiment, the method includes quantitative determination of the contractility or motion of the beating heart, such that changes in the depth of tissue can be used to control the channel depth or other treatment parameters. Retrolasing can also be achieved by mechanically piercing the tissue to a determined depth based on axial ranging measurements, and retracting the treatment tool while simultaneously delivering laser energy therefrom.

7. 发明授权

US5925012A Laser assisted drug delivery 失效
标题翻译：激光辅助药物输送
公开(公告)号：US5925012A
公开(公告)日：1999-07-20
申请号：US773872
申请日：1996-12-27
申请人： Douglas Murphy-Chutorian , Richard L. Mueller , Stuart D. Harman , Steve A. Daniel , Larry Witham , Robert Lincoln Lathrop, III , Bruce Richardson
发明人： Douglas Murphy-Chutorian , Richard L. Mueller , Stuart D. Harman , Steve A. Daniel , Larry Witham , Robert Lincoln Lathrop, III , Bruce Richardson
IPC分类号： A61B17/00 , A61B18/24 , A61M1/00
CPC分类号： A61B18/24 , A61B2017/00247 , A61B2018/00392
摘要： A drug delivery apparatus for dispensing predetermined volumes of drug, drug solution or other substances into an opening, such as a TMR channel in the human heart, or other laser treated area within the human body, the apparatus consisting of a bifurcated needle with a laser inlet for guiding a laser delivery means, such as an optical fiber or fiber bundle, to adjacent a surface of the human heart or other body structure for creating an opening, such as a TMR channel, or other laser treated area thereon. A drug inlet is for receiving the drug and transmitting the drug to the TMR channel or other laser treated area. Optionally, a piercing tip and/or suction device assists in positioning the apparatus adjacent the tissue to be treated. Drug is dispensed by manually or automatically actuating a piston or syringe element. A method of use is also disclosed.
摘要翻译：用于将预定体积的药物，药物溶液或其它物质分配到诸如人心脏中的TMR通道或人体内的其它激光处理区域的开口中的药物递送装置，该装置由具有激光的分叉针用于将诸如光纤或纤维束的激光传送装置引导到靠近人心或其他身体结构的表面以在其上形成诸如TMR通道或其他激光处理区域的开口。药物入口用于接收药物并将药物传输到TMR通道或其他激光治疗区域。可选地，刺穿尖端和/或抽吸装置有助于将装置定位在待处理组织附近。通过手动或自动启动活塞或注射器元件来分配药物。还公开了一种使用方法。

8. 发明申请

US20050113759A1 Catheter retainer 审中-公开
标题翻译：导管固定器
公开(公告)号：US20050113759A1
公开(公告)日：2005-05-26
申请号：US10720889
申请日：2003-11-24
申请人： Richard Mueller , James Kermode , Douglas Murphy-Chutorian
发明人： Richard Mueller , James Kermode , Douglas Murphy-Chutorian
IPC分类号： A61M5/32 , A61M25/02
CPC分类号： A61M25/02 , A61M2025/0233 , A61M2025/028
摘要： A catheter retainer includes a spacer and an anchor that coact to maintain a catheter in a predetermined position within a mammary duct during a ductal lavage procedure. The spacer and the anchor operate together to resist angular or axial displacement of the catheter. A catheter retainer kit is disclosed as well.
摘要翻译：导管保持器包括间隔件和锚固件，其在导管灌洗程序期间共同作用以将导管保持在乳房管道内的预定位置。间隔件和锚固件一起工作以抵抗导管的角度或轴向位移。还公开了导管保持套件。

9. 发明授权

US06846218B2 Breast stabilizing and positioning device and kit 失效
标题翻译：乳房稳定和定位装置和套件
公开(公告)号：US06846218B2
公开(公告)日：2005-01-25
申请号：US10427252
申请日：2003-04-30
申请人： James Kermode , Yumee Gang , Charles M. Schwimmer , Tammy Gravelle , Douglas Murphy-Chutorian
发明人： James Kermode , Yumee Gang , Charles M. Schwimmer , Tammy Gravelle , Douglas Murphy-Chutorian
IPC分类号： A41C3/00 , A41C3/12 , A61B10/00 , A61F13/14
CPC分类号： A61F13/145 , A61F2013/15016
摘要： A breast stabilizing and positioning device comprises a torso band for enveloping and securement about the chest of a human female patient, a breast elevating module and a breast stabilizing ring. The torso band defines a through aperture sized to receive a human breast there through. The breast elevating module is attached to the torso band, and comprises a base framing the through aperture of the torso band and a plurality of flexible, elongate tabs extending radially from the base. The breast stabilizing ring is adapted for securement about the areolar region of a human breast and defines an opening sized to receive a human breast nipple there through. The breast stabilizing ring is adapted for removable engagement with the tabs of the breast elevating module. The present devices assist in performing diagnostic procedures such as ductal lavage, or a surgical procedure, such as removal of ducts from the breast nipple.
摘要翻译：乳房稳定和定位装置包括用于围绕人类女性患者的胸部包围和固定的躯干带，乳房升降模块和乳房稳定环。躯干带定义了一个通孔，其大小通过接收人乳房。乳房提升模块附接到躯干带，并且包括框架通过躯干带的通孔的基部和从基部径向延伸的多个柔性细长的突出部。乳房稳定环适用于围绕人类乳房的非极性区域的固定，并且限定了通过其容纳人乳房乳头的开口。乳房稳定环适于与乳房升降模块的突出部可拆卸地接合。本装置有助于执行诊断程序，例如导管灌洗或外科手术，例如从乳房乳头去除导管。

10. 发明授权

US5713894A Combined mechanical/optical system for transmyocardial revascularization 失效
标题翻译：用于经心肌血运重建的组合机械/光学系统
公开(公告)号：US5713894A
公开(公告)日：1998-02-03
申请号：US607782
申请日：1996-02-27
申请人： Douglas Murphy-Chutorian , Stuart D. Harman
发明人： Douglas Murphy-Chutorian , Stuart D. Harman
IPC分类号： A61B18/20 , A61B17/00 , A61B18/24 , A61N5/06
CPC分类号： A61B18/245 , A61B2017/00247 , A61B2018/00392
摘要： The method for combined mechanical/laser myocardial revascularization of a human heart includes: inserting a mechanical piercing device and an elongated flexible lasing apparatus into the chest cavity of a patient; mechanically piercing, micro-tearing or spreading the epicardium of the heart; and then lasing from beneath the epicardium through the myocardium. The apparatus is guided to an area exterior to a ventricle of the patient's heart, and the distal end of the optical fiber apparatus is placed internal to the exterior wall of the heart through an opening which has been created by mechanically piercing, micro-tearing or spreading the epicardium, so that the myocardium and not the epicardium is irradiated with laser energy to allow passage of said optical fiber distal end or said laser energy into the left ventricular cavity without causing a laser irradiation of the epicardium which might be a cause of operative bleeding and for better allowing the sealing of the epicardium after the apparatus is removed.
摘要翻译：人心脏联合机械/激光心肌血运重建的方法包括：将机械穿刺装置和细长的柔性激光装置插入患者的胸腔; 机械穿刺，微裂或散布心脏的心外膜; 然后通过心肌从心外膜下射出。该装置被引导到患者心脏的心室的外部区域，并且光纤装置的远端通过开口被放置在心脏的外壁的内部，所述开口通过机械刺穿，微撕裂或扩散心外膜，使得心肌而不是心外膜被激光能量照射以允许所述光纤远端或所述激光能量通过到左心室，而不引起激光照射心外膜，这可能是手术的原因出血并且更好地允许在除去装置之后密封心外膜。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式