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    • 71. 发明申请
    • CRYOSTAT
    • US20070261429A1
    • 2007-11-15
    • US11718958
    • 2005-11-08
    • David Teehan
    • David Teehan
    • F25B19/00F25D25/00
    • A01N1/02A01N1/0257F17C2270/0509F25D19/006G01N1/06G01N1/42G01N2001/065
    • A cryostat includes a rotatable mounting arranged to rotate about a first rotational axis, the mounting extending substantially in a first plane, a sample plate arranged in use to support a sample, located on the rotatable mounting, and a heat sink located adjacent the side of the mounting distant from the sample plate. A thermal conductor extends between the sample plate and the heat sink. The conductor extends through an aperture in the rotatable mounting. A rotatable sample holder for a cryostat includes a sample plate having a first side arranged in use to support a sample, a drive gear arranged to rotate about a first rotational axis, and a driven gear arranged to rotate about a second rotational axis, engaged with the drive gear and coupled to the sample plate such that rotation of the drive gear causes the driven gear and sample holder to rotate. The first rotational axis does not intersect the second rotational axis.
    • 低温恒温器包括可旋转的安装件,其布置成围绕第一旋转轴线旋转,所述安装件基本上在第一平面中延伸;样品板,其布置用于支撑位于所述可旋转安装件上的样品;以及散热器, 远离样品板的安装。 导热体在样品板和散热片之间延伸。 导体延伸穿过可旋转安装件中的孔。 用于低温恒温器的可旋转样品保持器包括样品板,其具有布置成用于支撑样品的第一侧,布置成围绕第一旋转轴线旋转的驱动齿轮和布置成围绕第二旋转轴线旋转的从动齿轮, 驱动齿轮并联接到样品板,使得驱动齿轮的旋转导致从动齿轮和样品保持器旋转。 第一旋转轴线不与第二旋转轴线相交。
    • 72. 发明申请
    • Apparatus and method for preparing frozen tissue specimens
    • 用于制备冷冻组织标本的装置和方法
    • US20060236703A1
    • 2006-10-26
    • US11111431
    • 2005-04-21
    • David Rada
    • David Rada
    • F25D25/00F25D17/02
    • A01N1/02A01N1/0257F25D3/105
    • An apparatus and method for preparing frozen tissue specimens includes a base supporting a pair of rotary motion platforms and a center platform. The rotary motion platforms are movable from an open, side-by-side position to a closed, center platform-covering position. The rotary motion platform includes a plurality of cryogenic discs, each identified for receiving a plurality of tissue samples. The center platform includes a plurality of cryogenic discs, each having a plurality of bores for receiving object holders thereon, each object holder for receiving a frozen specimen thereon. The center platform cryogenic discs each have a channel system with intersecting peripheral, chordal and radial channels. A moistening tray includes structure having a closed, object holder wetting position and an open, object holder elevating position. Further disclosed is the use of a tissue orientation map, usable on temporary tattoos and tissue receiving sheets for specimen orientation and mapping of tumor roots. Also disclosed are labels and identification methods, fiber-reinforced embedding compounds and the use of treated polyester sheets for tissue specimen placement.
    • 用于制备冷冻组织标本的装置和方法包括支撑一对旋转运动平台和中心平台的基座。 旋转运动平台可以从打开的并排位置移动到封闭的中心平台覆盖位置。 旋转运动平台包括多个低温盘,每个被识别用于接收多个组织样本。 中心平台包括多个低温盘,每个低温盘具有多个用于在其上接收物体夹持器的孔,每个物体保持器用于在其上接收冷冻标本。 中心平台的低温圆盘每个都有一个通道系统,具有相交的外围,弦和径向通道。 润湿托盘包括具有封闭的物体保持器润湿位置和开放的物体保持器提升位置的结构。 进一步公开的是使用可用于临时纹身和组织接收片材以进行样本取向和肿瘤根部的映射的组织取向图。 还公开了标签和鉴定方法,纤维增强包埋化合物和用于组织样本放置的经处理的聚酯片的用途。
    • 73. 发明申请
    • Cryogenic storage system with improved temperature control
    • 低温储存系统具有改进的温度控制
    • US20060090479A1
    • 2006-05-04
    • US11299578
    • 2005-12-12
    • Michael IarocciStephen ValentineBrian Wowk
    • Michael IarocciStephen ValentineBrian Wowk
    • F17C3/08F17C13/02
    • A01N1/02A01N1/0257F17C2270/0509G01N1/42
    • A cryogenic storage system for cryogenic storage using liquid refrigerant is provided. The cryogenic storage system includes first and second vacuum vessels, a vacuum source, a quantity of a liquid refrigerant, and at least one temperature control assembly. An insulating wall may be provided on an interior surface of one of the vessels. A common vacuum condition is provided in voids that are present in the wall of the first and second vessels as well as in the insulating wall. The at least one temperature control assembly includes a power supply, a temperature sensor, a heater, and a conductive element. The at least one conductive element provides a link or thermal coupling between a space defined in the first vessel and the liquid refrigerant stored in the second vessel.
    • 提供了一种使用液体制冷剂的低温储存系统。 低温存储系统包括第一和第二真空容器,真空源,一定数量的液体制冷剂和至少一个温度控制组件。 绝缘壁可以设置在其中一个容器的内表面上。 在存在于第一和第二容器的壁以及绝缘壁中的空隙中提供常见的真空条件。 所述至少一个温度控制组件包括电源,温度传感器,加热器和导电元件。 所述至少一个导电元件提供在第一容器中限定的空间和存储在第二容器中的液体制冷剂之间的连接或热耦合。