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71. 发明授权

US08157559B2 Injection molding apparatus 有权
标题翻译：注塑设备
公开(公告)号：US08157559B2
公开(公告)日：2012-04-17
申请号：US12791581
申请日：2010-06-01
申请人： Takaaki Sato , Takashi Kato , Takeshi Kuriyama
发明人： Takaaki Sato , Takashi Kato , Takeshi Kuriyama
IPC分类号： B29C45/20
CPC分类号： B29C45/2737 , B29C2045/2754
摘要： An injection molding apparatus is provided with a die having a hot nozzle, and a manifold formed by a hot runner. A communication passage that is in communication with the cavity is provided in the die, a concave portion defined at an end portion of the die, and the hot nozzle includes a nozzle body of a cylindrical shape that is inserted in the communication passage, and a flange portion that is formed at an end side of the nozzle body and is exposed outside of the communication passage, in which a band heater that heats the nozzle body is inserted between the communication passage and the nozzle body, and a ring heater that heats this flange is inserted in the concave portion and between the communication passage and the flange.
摘要翻译：注射成型装置设有具有热喷嘴的模头和由热流道形成的歧管。与模腔连通的连通通道设置在模具中，限定在模具的端部的凹部，热喷嘴包括插入连通通路中的圆筒形状的喷嘴体，凸缘部，其形成在喷嘴主体的端部侧，并露出在连通通道的外侧，其中加热喷嘴体的带状加热器插入在连通通道和喷嘴体之间;以及环形加热器，其加热该喷嘴体凸缘插入到凹部中并且连通通道和凸缘之间。

72. 发明申请

US20070054266A1 Chemical sensor system 审中-公开
标题翻译：化学传感器系统
公开(公告)号：US20070054266A1
公开(公告)日：2007-03-08
申请号：US10516210
申请日：2003-05-28
申请人： Takaaki Sato , Junzo Hirono , Hiroshi Hamana , Masato Miyake , Tomohiro Yoshikawa , Jun Miyake
发明人： Takaaki Sato , Junzo Hirono , Hiroshi Hamana , Masato Miyake , Tomohiro Yoshikawa , Jun Miyake
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： G01N33/502 , G01N33/02 , G01N33/5008 , G01N33/5438
摘要： A chemical sensor utilizing a chemical receptor (for example, one stimulating the sense of taste or smell) is provided. More specifically speaking, such a receptor is introduced into cells and the cells are immobilized on a support to form a chip. This chip is then employed as a component of a sensor. This sensor shows a reaction almost the same as the body's perception of the taste or smell or sense, thereby enabling analysis. Thus, it is also usable as an artificial sensory organ. Moreover, this sensor is usable in diagnosis, which imparts a high industrial usefulness to it.
摘要翻译：提供了利用化学受体（例如刺激味觉或嗅觉的化学受体）的化学传感器。更具体地说，将这种受体引入细胞中，将细胞固定在载体上以形成芯片。然后将该芯片用作传感器的组件。该传感器显示与身体对味道或气味或感觉的感觉几乎相同的反应，从而能够进行分析。因此，它也可用作人造感觉器官。此外，该传感器可用于诊断，赋予其高的工业用途。

73. 发明申请

US20060293054A1 Radio control apparatus and link securing method 审中-公开
公开(公告)号：US20060293054A1
公开(公告)日：2006-12-28
申请号：US11283513
申请日：2005-11-21
申请人： Kazunori Obata , Takaaki Sato
发明人： Kazunori Obata , Takaaki Sato
IPC分类号： H04Q7/20
CPC分类号： H04W36/26
摘要： A radio control apparatus 10 is provided with a call management system 18 configured so that, when a mobile station in communication with a first base station by a first communication link requests diversity handover with a second base station, the call management system 18 retrieves a potential information rate that is not higher than an information rate of the first communication link and that is highest, from an information rate table 31 storing information about information rates of communication links securable in the second base station under other radio control apparatus; and a link management system 20 configured so that, when the potential information rate is lower than that of the first communication link, the link management system 20 instructs the first base station to change the first communication link to a second communication link communicable at the potential information rate; the call management system 18 requests the other radio control apparatus to secure a third communication link communicable at the potential information rate and to instruct the second base station to perform communication with the mobile station by the third communication link.

74. 发明授权

US07035639B2 Radio control apparatus and link securing method 有权
公开(公告)号：US07035639B2
公开(公告)日：2006-04-25
申请号：US10346109
申请日：2003-01-17
申请人： Kazunori Obata , Takaaki Sato
发明人： Kazunori Obata , Takaaki Sato
IPC分类号： H04Q7/20
CPC分类号： H04W36/26
摘要： A radio control apparatus 10 is provided with a call management system 18 configured so that, when a mobile station in communication with a first base station by a first communication link requests diversity handover with a second base station, the call management system 18 retrieves a potential information rate that is not higher than an information rate of the first communication link and that is highest, from an information rate table 31 storing information about information rates of communication links securable in the second base station under other radio control apparatus; and a link management system 20 configured so that, when the potential information rate is lower than that of the first communication link, the link management system 20 instructs the first base station to change the first communication link to a second communication link communicable at the potential information rate; the call management system 18 requests the other radio control apparatus to secure a third communication link communicable at the potential information rate and to instruct the second base station to perform communication with the mobile station by the third communication link.

75. 发明授权

US06935072B2 Weather strip having variable length holding lip 有权
标题翻译：天气条具有不同长度的嘴唇
公开(公告)号：US06935072B2
公开(公告)日：2005-08-30
申请号：US10193582
申请日：2002-07-12
申请人： Harumi Kogiso , Kiminori Mine , Masaki Ohashi , Takaaki Sato , Tomofumi Nishikawa , Masahiro Nozaki , Toshihiro Nahara
发明人： Harumi Kogiso , Kiminori Mine , Masaki Ohashi , Takaaki Sato , Tomofumi Nishikawa , Masahiro Nozaki , Toshihiro Nahara
IPC分类号： B60J10/00 , B60J10/08 , E06B7/16
CPC分类号： B60J10/24 , B60J10/18 , B60J10/22 , B60J10/265 , B60J10/30 , B60J10/32 , B60J10/33 , B60J10/80
摘要： A weather strip includes a trim body having a generally U-shaped cross section, a hollow seal portion that protrudes from an outside surface of the trim body, and a holding lip formed on the trim body so as to extend from an inside surface of the trim body toward the inside of the trim body. The weather strip is mounted on the vehicle body such that the trim body is held by a flange provided at a periphery of a door opening of a motor vehicle. The weather strip is formed by extrusion molding such that the length of the holding lip is changed in a stepped manner in accordance with the thickness of the flange.
摘要翻译：防风条包括具有大致U形横截面的装饰体，从装饰主体的外表面突出的中空密封部分和形成在装饰主体上的保持唇部，以便从该内侧表面延伸修剪身体朝向修剪体的内部。风挡条安装在车身上，使得装饰体由设置在机动车辆的门开口周边的凸缘保持。通过挤压成型形成防风条，使得保持唇缘的长度根据凸缘的厚度以阶梯式改变。

76. 发明授权

US06911526B2 Compounds that inhibit the interaction between signal-transducing proteins and the GLGF (PDZ/DHR) domain and uses thereof 失效
标题翻译：抑制信号转导蛋白与GLGF（PDZ / DHR）结构域之间相互作用的化合物及其用途
公开(公告)号：US06911526B2
公开(公告)日：2005-06-28
申请号：US08681219
申请日：1996-07-22
申请人： Takaaki Sato , Junn Yanagisawa
发明人： Takaaki Sato , Junn Yanagisawa
IPC分类号： A61K45/00 , A61K38/00 , A61K38/08 , A61P31/12 , A61P35/00 , A61P43/00 , C07K5/10 , C07K7/06 , C07K7/08 , C07K14/47 , G01N33/50 , C07K14/705
CPC分类号： C07K14/4747 , A61K38/00 , G01N33/5011 , G01N2333/705 , G01N2333/70571 , G01N2333/70578 , G01N2333/912
摘要： This invention provides for a composition capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein. This invention also provides a method of identifying a compound capable of inhibiting specific binding between a signal-transducing protein and a cytoplasmic protein. This invention also provides a method of inhibiting the proliferation of cancer cells. This invention also provides a method of treating cancer with a composition in an amount effective to result in an amount in apoptosis of the cells. This invention also provides a method of inhibiting the proliferation of virally infected cells. This invention also provides for a method of treating a virally-infected subject with a composition in an amount effective to result in apoptosis of the cells. This invention also provides for pharmaceutical compositions.
摘要翻译：本发明提供能够抑制信号转导蛋白和细胞质蛋白之间的特异性结合的组合物。本发明还提供鉴定能够抑制信号转导蛋白和细胞质蛋白之间特异性结合的化合物的方法。本发明还提供了抑制癌细胞增殖的方法。本发明还提供了一种用有效导致细胞凋亡量的组合物治疗癌症的方法。本发明还提供了抑制病毒感染细胞增殖的方法。本发明还提供了用有效导致细胞凋亡的量的组合物治疗病毒感染的受试者的方法。本发明还提供药物组合物。

77. 发明授权

US5876939A FAS associated proteins 失效
标题翻译： FAS相关蛋白
公开(公告)号：US5876939A
公开(公告)日：1999-03-02
申请号：US858311
申请日：1997-05-19
申请人： John C. Reed , Takaaki Sato
发明人： John C. Reed , Takaaki Sato
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61K48/00 , C07K14/47 , C12N5/10 , C12N9/16 , C12N15/00 , C12N15/10 , C12N15/55 , C12P21/08 , C12Q1/04 , C12Q1/68 , C12R1/91 , G01N33/53
CPC分类号： C07K14/4747 , C12N15/1055 , C12N9/16 , C12Q1/6897 , A61K38/00
摘要： The present invention provides mammalian protein tyrosine phosphatases, human PTP-BAS type 4, human PTP-BAS type 5a and mouse PTP-BAS type 5b, each of which is a Fas-associated protein (FAP), nucleic acid molecules encoding a PTP-BAS type 4 or a PTP-BAS type 5 and antibodies specific for a PTP-BAS type 4 or for a PTP-BAS type 5. The invention also provides methods for identifying FAP's, which can associate with Fas and can modulate apoptosis. The invention also provides screening assays for identifying an agent that can effectively alter the association of a FAP with Fas and, therefore, can increase or decrease the level of apoptosis in a cell. The invention further provides methods of modulating apoptosis in a cell by introducing into the cell a nucleic acid molecule encoding a PTP-BAS or fragment of a PTP-BAS or an antisense nucleotide sequence, which is complementary to a portion of a nucleic acid molecule encoding a PTP-BAS. The invention also provides a method of using a reagent that can specifically bind to a FAP to diagnose a pathology that is characterized by an increased or decreased level of apoptosis in a cell. The invention also provides methods of modulating apoptosis in a cell by contacting the cell with an agent that effectively alters the association of a FAP and Fas in a cell or alters the activity of a FAP in a cell.
摘要翻译：本发明提供哺乳动物蛋白酪氨酸磷酸酶，人PTP-BAS型4，人PTP-BAS型5a和小鼠PTP-BAS型5b，其各自是Fas相关蛋白（FAP），编码PTP- BAS型4或PTP-BAS型5和PTP-BAS型4或PTP-BAS型5特异性抗体。本发明还提供鉴定FAP的方法，其可与Fas结合并可调节细胞凋亡。本发明还提供用于鉴定能够有效改变FAP与Fas的缔合的试剂的筛选测定，因此可以增加或降低细胞凋亡水平。本发明还提供了通过向细胞中引入编码PTP-BAS或PTP-BAS或反义核苷酸序列片段的核酸分子来调节细胞凋亡的方法，所述核酸分子与编码的核酸分子的一部分互补一个PTP-BAS。本发明还提供了使用能够特异性结合FAP的试剂来诊断细胞凋亡水平升高或降低的病理学的方法。本发明还提供了通过使细胞与有效改变细胞中FAP和Fas的缔合的试剂接触而改变细胞凋亡的方法或改变细胞中FAP的活性的方法。

78. 发明授权

US5632994A Fas associated proteins 失效
标题翻译： Fas相关蛋白
公开(公告)号：US5632994A
公开(公告)日：1997-05-27
申请号：US410804
申请日：1995-03-27
申请人： John C. Reed , Takaaki Sato
发明人： John C. Reed , Takaaki Sato
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61K48/00 , C07K14/47 , C12N5/10 , C12N9/16 , C12N15/00 , C12N15/10 , C12N15/55 , C12P21/08 , C12Q1/04 , C12Q1/68 , C12R1/91 , A61K39/00 , C07K16/00 , G01N33/53
CPC分类号： C07K14/4747 , C12N15/1055 , C12N9/16 , C12Q1/6897 , A61K38/00
摘要： The present invention provides mammalian protein tyrosine phosphatases, human PTP-BAS type 4, human PTP-BAS type 5a and mouse PTP-BAS type 5b, each of which is a Fas-associated protein (FAP), nucleic acid molecules encoding a PTP-BAS type 4 or a PTP-BAS type 5 and antibodies specific for a PTP-BAS type 4 or for a PTP-BAS type 5. The invention also provides methods for identifying FAP's, which can associate with Fas and can modulate apoptosis. The invention also provides screening assays for identifying an agent that can effectively alter the association of a FAP with Fas and, therefore, can increase or decrease the level of apoptosis in a cell. The invention further provides methods of modulating apoptosis in a cell by introducing into the cell a nucleic acid molecule encoding a PTP-BAS or fragment of a PTP-BAS or an antisense nucleotide sequence, which is complementary to a portion of a nucleic acid molecule encoding a PTP-BAS. The invention also provides a method of using a reagent that can specifically bind to a FAP to diagnose a pathology that is characterized by an increased or decreased level of apoptosis in a cell. The invention also provides methods of modulating apoptosis in a cell by contacting the cell with an agent that effectively alters the association of a FAP and Fas in a cell or alters the activity of a FAP in a cell.
摘要翻译：本发明提供哺乳动物蛋白酪氨酸磷酸酶，人PTP-BAS型4，人PTP-BAS型5a和小鼠PTP-BAS型5b，其各自是Fas相关蛋白（FAP），编码PTP- BAS型4或PTP-BAS型5和PTP-BAS型4或PTP-BAS型5特异性抗体。本发明还提供鉴定FAP的方法，其可与Fas结合并可调节细胞凋亡。本发明还提供用于鉴定能够有效改变FAP与Fas的缔合的试剂的筛选测定，因此可以增加或降低细胞凋亡水平。本发明还提供了通过向细胞中引入编码PTP-BAS或PTP-BAS或反义核苷酸序列片段的核酸分子来调节细胞凋亡的方法，所述核酸分子与编码的核酸分子的一部分互补一个PTP-BAS。本发明还提供了使用能够特异性结合FAP的试剂来诊断细胞凋亡水平升高或降低的病理学的方法。本发明还提供了通过使细胞与有效改变细胞中FAP和Fas的缔合的试剂接触而改变细胞凋亡的方法或改变细胞中FAP的活性的方法。

79. 发明授权

US09078185B2 Mobile communication system, network apparatus, and mobile communication method 有权
标题翻译：移动通信系统，网络设备和移动通信方式
公开(公告)号：US09078185B2
公开(公告)日：2015-07-07
申请号：US13636745
申请日：2011-03-23
申请人： Takayuki Tsuneda , Hiroyuki Hosono , Takaaki Sato , Takeshi Terayama , Masafumi Masuda
发明人： Takayuki Tsuneda , Hiroyuki Hosono , Takaaki Sato , Takeshi Terayama , Masafumi Masuda
IPC分类号： H04W72/04 , H04W36/08 , H04W36/32
CPC分类号： H04W36/08 , H04W36/32
摘要： A mobile communication system 100 includes a selection unit 25 configured to select a transition target frequency from the plurality of frequencies when a condition under which a mobile communication terminal not utilize a transition source frequency being any of the plurality of frequencies is fulfilled, and an instruction unit 22 configured to instruct the mobile communication terminal to perform a transition to the transition target frequency selected by the selection unit. The selection unit 25 excludes the transition source frequency from a frequency candidate to be utilized by the mobile communication terminal until an elapsed time after the instruction of the transition to the transition target frequency exceeds a predetermined time.
摘要翻译：移动通信系统100包括：选择单元25，被配置为当移动通信终端不利用多个频率中的任一个的转换源频率的条件时，从多个频率中选择转换目标频率，以及指令单元22，被配置为指示移动通信终端执行到由选择单元选择的转移目标频率的转变。选择单元25从移动通信终端使用的频率候选中排除转换源频率，直到转移到转换目标频率的指令超过预定时间之后的经过时间。

80. 发明授权

US08983428B2 Mobile communication system, home base station, and mobile station 有权
标题翻译：移动通信系统，家庭基站和移动台
公开(公告)号：US08983428B2
公开(公告)日：2015-03-17
申请号：US12740536
申请日：2008-10-28
申请人： Mikio Iwamura , Masafumi Masuda , Takaaki Sato , Takehiro Nakamura
发明人： Mikio Iwamura , Masafumi Masuda , Takaaki Sato , Takehiro Nakamura
IPC分类号： H04W4/00 , H04W48/08
CPC分类号： H04W48/08
摘要： In a mobile communication system according to the present invention, the mobile communication system is configured to manage a specific mobile station which is allowed to communicate through a CSG cell under the control of a home base station (Home-eNB); and a general mobile station (UE) other than the specific mobile station is configured to be capable of using the CSG cell as a camped cell, only when broadcast information indicating an allowance of a camping in the specific cell is received.
摘要翻译：在根据本发明的移动通信系统中，移动通信系统被配置为在家庭基站（Home-eNB）的控制下管理允许通过CSG小区通信的特定移动台; 并且除了特定移动台之外的通用移动台（UE）被配置为仅当接收到指示特定小区中的露营允许的广播信息时才能够使用CSG小区作为驻留小区。

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