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71. 发明申请

US20050158725A1 Method of amplifying nucleic acid by electromagnetic induction heating and reaction container and reaction device to be used therein 审中-公开
标题翻译：通过电磁感应加热和反应容器放大核酸的方法及其中使用的反应装置
公开(公告)号：US20050158725A1
公开(公告)日：2005-07-21
申请号：US10510819
申请日：2003-09-24
申请人： Tetsuo Yukimasa , Nobuhiko Ozaki , Masaya Nakatani , Hidenobu Yaku , Hiroaki Oka , Kimi Fukahi
发明人： Tetsuo Yukimasa , Nobuhiko Ozaki , Masaya Nakatani , Hidenobu Yaku , Hiroaki Oka , Kimi Fukahi
IPC分类号： C07H21/00 , C12Q1/68 , C12M1/34
CPC分类号： C07H21/00 , C12Q1/6844
摘要： The present invention provides a reaction container, a reaction device, and a method of amplifying a nucleic acid, which are suitable for locally heating a sample which contains a nucleic acid, enable rapid control of temperature changes in the sample, provide easy fabrication, and are low cost. The invention provides a reaction container used for a nucleic acid amplification reaction, which includes a sample holding portion formed from a cavity in the reaction container; and a heating element for heating a sample which contains a nucleic acid and which is held in the sample holding portion, wherein the heating element is made of a conductive material and arranged at a location where the sample or the sample and the periphery of the cavity is (are) to be locally heated, the conductive material generating heat by electromagnetic induction.
摘要翻译：本发明提供一种反应容器，反应装置和扩增核酸的方法，其适用于局部加热含有核酸的样品，能够快速控制样品中的温度变化，提供容易的制造，以及是低成本的。本发明提供了用于核酸扩增反应的反应容器，其包括由反应容器中的空腔形成的样品保持部分; 以及加热元件，用于加热含有核酸并被保持在样品保持部分中的样品，其中所述加热元件由导电材料制成并且布置在样品或样品和空腔周边的位置被局部加热，导电材料通过电磁感应产生热量。

72. 发明申请

US20050000934A1 Method for manufacturing resonant device 失效
标题翻译：制造谐振装置的方法
公开(公告)号：US20050000934A1
公开(公告)日：2005-01-06
申请号：US10494640
申请日：2003-08-20
申请人： Masaya Nakatani , Hirofumi Tajika
发明人： Masaya Nakatani , Hirofumi Tajika
IPC分类号： G01C19/56 , G01C19/5628 , H01L41/08 , H01L41/22 , H01L41/23 , H01L41/332 , H03H3/02 , H03H9/21 , H01B13/00
CPC分类号： G01C19/5628 , G01C19/5621 , H03H9/21 , H03H2003/026
摘要： A piezoelectric member and an electrode are formed over a silicon substrate. The piezoelectric member and the electrode are patterned by photolithography. The silicon substrate is etched to form a body. A protective film is formed on at least one surface of the body. Another surface having no protective film thereon is etched to obtain a resonant device. The body is etched in its thickness direction accurately while a resonance frequency of the body is measured. The manufacturing processes allow the resonance frequency and a gap frequency of the resonant device to be adjusted to predetermined values.
摘要翻译：在硅衬底上形成压电元件和电极。压电元件和电极通过光刻图案化。硅衬底被蚀刻以形成体。在身体的至少一个表面上形成保护膜。在其上没有保护膜的另一表面被蚀刻以获得谐振装置。在测量身体的共振频率的同时，精确地蚀刻身体的厚度方向。制造过程允许共振频率和谐振装置的间隙频率被调节到预定值。

73. 发明授权

US06588883B2 Liquid injector, method of manufacturing the injector, and ink-jet spray using the injector 有权
标题翻译：液体注射器，制造喷射器的方法，以及使用喷射器的喷墨喷射
公开(公告)号：US06588883B2
公开(公告)日：2003-07-08
申请号：US10046531
申请日：2002-01-14
申请人： Masaya Nakatani , Katsumasa Miki
发明人： Masaya Nakatani , Katsumasa Miki
IPC分类号： B41J204
CPC分类号： B41J2/161 , B41J2/1623 , B41J2/1628 , B41J2/1631 , B41J2/1632
摘要： A liquid injector having a liquid eject outlet side reduced in size is provided. In a head block of the liquid injector, a pressurizing chamber is linearly aligned with a liquid eject outlet and liquid feed inlet.
摘要翻译：提供具有液体喷射出口侧尺寸减小的液体喷射器。在液体注射器的头部块中，加压室与液体喷射出口和液体进料入口线性对准。

74. 发明授权

US08687939B2 Recording/reproducing system, recording/reproducing apparatus, and method for controlling recording/reproducing apparatus 失效
标题翻译：记录/再现系统，记录/再现装置和用于控制记录/再现装置的方法
公开(公告)号：US08687939B2
公开(公告)日：2014-04-01
申请号：US12439201
申请日：2007-07-12
申请人： Hisashi Ohashi , Masaya Nakatani
发明人： Hisashi Ohashi , Masaya Nakatani
IPC分类号： H04N5/775
CPC分类号： H04N5/23293 , G11B31/006 , H04N5/23216 , H04N5/77 , H04N5/781
摘要： According to the present invention, even in the case where an external recording apparatus is designed to be small and capable of being connected to various types of video equipment and is equipped with various types of operation units, an alarm display section, and so on, if the external recording apparatus is connected to a main apparatus, a menu for the external recording apparatus is provided to the main apparatus to accept a setting for the external recording apparatus with the main apparatus.
摘要翻译：根据本发明，即使在将外部记录装置设计得很小并且能够连接到各种类型的视频设备并且配备有各种类型的操作单元，报警显示部分等的情况下，如果外部记录设备连接到主设备，则将外部记录设备的菜单提供给主设备以接受用主设备的外部记录设备的设置。

75. 发明授权

US08333896B2 Component separation device, method of manufacturing the same, and method of separating components using the same 有权
标题翻译：元件分离装置及其制造方法以及使用其分离成分的方法
公开(公告)号：US08333896B2
公开(公告)日：2012-12-18
申请号：US10543835
申请日：2004-11-25
申请人： Masaya Nakatani
发明人： Masaya Nakatani
IPC分类号： C02F1/34
CPC分类号： C02F1/34 , B01D21/283 , B01L3/502753 , B01L2400/0439
摘要： A component separation device includes a substrate having a flow path formed therein and arranged to store a fluid containing a liquid component and a solid component, and an actuator causing the fluid stored in the flow path to vibrate. The actuator includes a first electrode provided on the substrate apart from the flow path, and a first piezoelectric member provided on the first electrode, and a second electrode provided on the first piezoelectric member. This separation device prevents the actuator from being contaminated by the fluid, and separates the components efficiently.
摘要翻译：部件分离装置包括具有形成在其中的流路的基板，其布置成存储包含液体部件和固体部件的流体，以及使存储在流路中的流体振动的致动器。致动器包括设置在离开流路的基板上的第一电极和设置在第一电极上的第一压电元件和设置在第一压电元件上的第二电极。该分离装置防止致动器被流体污染，并且有效地分离组件。

76. 发明授权

US08257962B2 Extracellular potential measuring device and its manufacturing method 有权
标题翻译：细胞外电位测定装置及其制造方法
公开(公告)号：US08257962B2
公开(公告)日：2012-09-04
申请号：US10513392
申请日：2004-03-08
申请人： Masaya Nakatani , Hiroaki Oka , Fumiaki Emoto
发明人： Masaya Nakatani , Hiroaki Oka , Fumiaki Emoto
IPC分类号： C12M1/42 , C12M3/00 , C12N13/00
CPC分类号： G01N33/48728
摘要： An extracellular potential measuring device includes a plate portion having a first surface and a second surface opposite to the first surface, and an electrode provided on the second surface of the plate portion. In the plate portion, a pocket having an opening which opens to the first surface is formed, and a through-hole communicating to the second surface from the pocket. The through-hole communicates from a position which is closer to the opening than a deepest point of the first pocket. The electrode is provided around of the opening of the through-hole. In this device, even if a cell to be examined does not reach the deepest point of the pocket, a cell membrane of the cell can tightly attaches onto the through-hole securely without a clearance. Hence, culture solution inside the through-hole is isolated from culture solution over an upper surface of the plate portion, thereby allowing electrochemical changes caused by activities of the cell to be detected efficiently with a detector electrode.
摘要翻译：细胞外电位测量装置包括具有第一表面和与第一表面相对的第二表面的板部分，以及设置在板部分的第二表面上的电极。在该板部分中，形成具有向第一表面开口的开口的口袋，以及从口袋连通到第二表面的通孔。通孔从比第一口袋的最深点更靠近开口的位置连通。电极设置在通孔的开口周围。在该装置中，即使要检查的细胞未达到口袋的最深点，细胞的细胞膜可以牢固地紧贴在通孔上而没有间隙。因此，通孔内部的培养液在培养液的上表面上与培养液分离，从而能够通过检测器电极有效地检测细胞活性引起的电化学变化。

77. 发明申请

US20100019782A1 CELLULAR POTENTIAL MEASUREMENT CONTAINER 审中-公开
标题翻译：细胞电位测量容器
公开(公告)号：US20100019782A1
公开(公告)日：2010-01-28
申请号：US11916947
申请日：2006-06-28
申请人： Eiji Watanabe , Akira Higuchi , Masaya Nakatani
发明人： Eiji Watanabe , Akira Higuchi , Masaya Nakatani
IPC分类号： G01R27/08
CPC分类号： G01N33/48728
摘要： The present invention provides a cellular potential measurement container that can measure a cellular potential with high accuracy while suppressing noise even when the number of the cells to be subjected to the measurement is increased. The cellular potential measurement container includes a first solution reservoir 14, a second solution reservoir 15, a partition substrate 18, a first electrode 27a, a second electrode 27b, a first measurement terminal 13a, and a second measurement terminal 13b. The first solution reservoir 14 and the second solution reservoir 15 are partitioned with the partition substrate 18, and the partition substrate 18 has a through hole 19. A first end of the through hole 19 is open toward the first solution reservoir 14 while a second end of the through hole 19 is open toward the second solution reservoir 15. The opening at the first end of the through hole 19 can hold a cell. The first electrode 27a is arranged so that a first solution can come into contact with the first electrode, and the second electrode 27b is arranged so that a second solution can come into contact with the second electrode. In the cellular potential measurement container with the above configuration, an electric signal amplifying device 16 further is provided, and the first measurement terminal 13a or the second measurement terminal 13b is connected to the first electrode 27a or the second electrode 27b via this electric signal amplifying device 16.
摘要翻译：本发明提供一种细胞电位测量容器，即使在要进行测量的细胞数量增加的同时，也可以以高精度测量细胞电位，同时抑制噪声。细胞电位测量容器包括第一溶液储存器14，第二溶液储存器15，分隔基板18，第一电极27a，第二电极27b，第一测量端子13a和第二测量端子13b。第一溶液储存器14和第二溶液储存器15被分隔基板18分隔开，分隔基板18具有通孔19.通孔19的第一端向第一溶液储存器14开口，而第二端通孔19朝向第二溶液储存器15开口。通孔19的第一端处的开口可以容纳电池。第一电极27a被布置成使得第一溶液可以与第一电极接触，并且第二电极27b被布置成使得第二溶液可以与第二电极接触。在具有上述结构的细胞电位测量容器中，还设置有电信号放大装置16，并且第一测量端子13a或第二测量端子13b经由该电信号放大与第一电极27a或第二电极27b连接设备16。

78. 发明申请

US20080223132A1 Vibration Piezoelectric Acceleration Sensor 失效
标题翻译：振动压电加速度传感器
公开(公告)号：US20080223132A1
公开(公告)日：2008-09-18
申请号：US10585618
申请日：2005-02-14
申请人： Jiro Terada , Masaya Nakatani , Takami Ishida
发明人： Jiro Terada , Masaya Nakatani , Takami Ishida
IPC分类号： G01P15/09
CPC分类号： G01P15/09 , G01P15/097 , G01P15/18 , G01P2015/084
摘要： A vibration piezoelectric acceleration sensor including a pair of diaphragms linearly and oppositely disposed on a frame, a support body supporting the diaphragm, and a holding part holding the support body slidably in a linear direction, and another pair of diaphragms disposed linearly and oppositely crossing the pair of diaphragms detecting acceleration in two axes, i.e. X and Y directions. The diaphragms are extended and retracted by the acceleration transmitted to the support body through the holding part, changing a natural oscillation frequency. Accordingly, a high change ratio of resonance frequency can be provided with the detection of the acceleration, and the acceleration in two axes directions can be detected without being affected by a change in temperature.
摘要翻译：一种振动压电加速度传感器，包括线性地并相对地设置在框架上的一对隔膜，支撑隔膜的支撑体以及沿直线方向可滑动地保持支撑体的保持部以及与线状地相反地交叉的另一对隔膜一对隔膜检测两轴的加速度，即X和Y方向。通过保持部分传递到支撑体的加速度使膜片伸长和缩回，改变固有的振荡频率。因此，可以通过检测加速度来提供高谐振频率的变化率，并且可以在不受温度变化的影响的情况下检测两个轴向的加速度。

79. 发明授权

US07396673B2 Device for measuring extracellular potential 有权
标题翻译：用于测量细胞外电位的装置
公开(公告)号：US07396673B2
公开(公告)日：2008-07-08
申请号：US10991269
申请日：2004-11-17
申请人： Masaya Nakatani , Nobuhiko Ozaki , Hiroaki Oka
发明人： Masaya Nakatani , Nobuhiko Ozaki , Hiroaki Oka
IPC分类号： C12M1/34
CPC分类号： G01N33/48728
摘要： A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.
摘要翻译：用于测量细胞外电位的感测元件，包括衬底，设置在衬底中的阱，设置在阱的壁上的引导部分和形成在衬底的下表面处的检测电极。指导部分是指导药物。井在底部设置有凹陷，并且第一通孔穿过基底的凹陷和下表面。该井用于将主体细胞，培养液和药物混合在一起。上述构成的感测元件精确地测量由被摄体单元产生的变化。

80. 发明授权

US07083740B2 Method for manufacturing resonant device 失效
标题翻译：制造谐振装置的方法
公开(公告)号：US07083740B2
公开(公告)日：2006-08-01
申请号：US10494640
申请日：2003-08-20
申请人： Masaya Nakatani , Hirofumi Tajika
发明人： Masaya Nakatani , Hirofumi Tajika
IPC分类号： B34C1/22
CPC分类号： G01C19/5628 , G01C19/5621 , H03H9/21 , H03H2003/026
摘要： A piezoelectric member and an electrode are formed over a silicon substrate. The piezoelectric member and the electrode are patterned by photolithography. The silicon substrate is etched to form a body. A protective film is formed on at least one surface of the body. Another surface having no protective film thereon is etched to obtain a resonant device. The body is etched in its thickness direction accurately while a resonance frequency of the body is measured. The manufacturing processes allow the resonance frequency and a gap frequency of the resonant device to be adjusted to predetermined values.
摘要翻译：在硅衬底上形成压电元件和电极。压电元件和电极通过光刻图案化。硅衬底被蚀刻以形成体。在身体的至少一个表面上形成保护膜。在其上没有保护膜的另一表面被蚀刻以获得谐振装置。在测量身体的共振频率的同时，精确地蚀刻身体的厚度方向。制造过程允许共振频率和谐振装置的间隙频率被调节到预定值。

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