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71. 发明授权

US07853033B2 Hearing aid design 失效
标题翻译：助听器设计
公开(公告)号：US07853033B2
公开(公告)日：2010-12-14
申请号：US11752196
申请日：2007-05-22
申请人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
发明人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
IPC分类号： H04R25/00
CPC分类号： H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要： A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, a microphone, and a hollow tube which contains a steroid or drug. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.
摘要翻译：助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。助听器模块包含扬声器或听觉换能器，为模块供电的电池或其它电源，信号处理电路，麦克风和含有类固醇或药物的中空管。模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。遥控单元允许用户进行简单的调节，例如音量和/或音调（频率）控制。

72. 发明申请

US20100217243A1 PARTIALLY IMPLANTABLE MEDICAL DEVICES AND TREATMENT METHODS ASSOCIATED WITH SAME 审中-公开
标题翻译：部分可植入医疗器械及与其相关的治疗方法
公开(公告)号：US20100217243A1
公开(公告)日：2010-08-26
申请号：US12390437
申请日：2009-02-21
申请人： Alfred E. Mann
发明人： Alfred E. Mann
IPC分类号： A61M5/142
CPC分类号： A61M39/0247 , A61M5/1407 , A61M5/14244 , A61M15/00 , A61M2202/064 , A61M2205/12 , A61M2205/50 , A61M2205/8206
摘要： Partially implantable medical devices and methods associated with partially implantable medical devices.
摘要翻译：部分可植入的医疗设备和与部分可植入医疗设备相关的方法。

73. 发明申请

US20080147050A1 External Infusion Device With Remote Programming, Bolus Estimator and/or Vibration Alarm Capabilities 审中-公开
公开(公告)号：US20080147050A1
公开(公告)日：2008-06-19
申请号：US11670395
申请日：2007-02-01
申请人： Alfred E. Mann , James D. Causey , Alan Haubach , Luis J. Malave , John Livingston , Cliff Hague , Chad Srisathapat , Jay Yonemoto , Deborah Ruppert , Dennis P. Bishop , Adrian Gut , Bob Murtfeldt
发明人： Alfred E. Mann , James D. Causey , Alan Haubach , Luis J. Malave , John Livingston , Cliff Hague , Chad Srisathapat , Jay Yonemoto , Deborah Ruppert , Dennis P. Bishop , Adrian Gut , Bob Murtfeldt
IPC分类号： A61K9/22
CPC分类号： A61M5/1723 , A61M5/14244 , A61M5/172 , A61M5/36 , A61M2005/1402 , A61M2005/1403 , A61M2205/18 , A61M2205/3561 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2209/01 , A61M2230/201 , G06F19/00 , G06F19/3468 , Y02A90/22 , Y02A90/26 , Y10S128/903
摘要： An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an indication device. The receiver is coupled to the housing and for receiving remotely generated commands. The processor is coupled to the housing and the receiver to receive remotely generated commands and to control the external infusion device in accordance with the commands. The indication device indicates when a command has been received and indicates when the command is being utilized to control the external infusion device so that the external infusion device is capable of being concealed from view when being remotely commanded. The remote commander includes a commander housing, a keypad for transmitting commands, and a transmitter for transmitting commands to the receiver of the external infusion device.

74. 发明申请

US20080139874A1 Fully Implantable Hearing Aid System 失效
标题翻译：全植入式助听器系统
公开(公告)号：US20080139874A1
公开(公告)日：2008-06-12
申请号：US11883728
申请日：2006-02-23
申请人： William Slattery , Alfred E. Mann , Byron L. Moran
发明人： William Slattery , Alfred E. Mann , Byron L. Moran
IPC分类号： H04R25/00
CPC分类号： H04R25/604 , H04R25/554 , H04R25/558 , H04R2225/67
摘要： A fully implantable hearing aid system comprised of an implantable sound generator module and an implantable sound receiver module connected by an implantable electric cable. The system includes: a) a sound generator module configured for implantation in subcutaneous tissue to place an output electric/acoustic (E/A) transducer, e.g., a speaker, immediately adjacent to, or preferably, extending percutaneously into, a patient's outer ear canal; b) a sound receiver module configured for implantation proximate to a patient's pinna to place an input acoustic/electric (AJE) transducer, e.g., a microphone, so that it is acoustically isolated from the E/A transducer; and c) an electric cable configured for implantation in subcutaneous tissue for directly electrically connecting said sound receiver module and said sound generator module.
摘要翻译：一种完全可植入的助听器系统，包括由可植入电缆连接的可植入声音发生器模块和可植入声音接收器模块。该系统包括：a）声音发生器模块，其配置用于植入皮下组织以将输出的电/声（E / A）换能器，例如扬声器紧邻或优选地经皮延伸到患者的外耳运河; b）声音接收器模块，其配置用于在患者的耳廓附近植入以放置例如麦克风的输入声/电（AJE）换能器，使得其与E / A换能器声学隔离; 以及c）配置用于植入皮下组织以直接电连接所述声音接收器模块和所述声音发生器模块的电缆。

75. 发明授权

US06872200B2 External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities 有权
公开(公告)号：US06872200B2
公开(公告)日：2005-03-29
申请号：US10401245
申请日：2003-03-27
申请人： Alfred E. Mann , James D. Causey, III , Alan Haubach , Luis J. Malave , John Livingston , Cliff Hague , Chad Srisathapat , Jay Yonemoto , Deborah Ruppert , Dennis P. Bishop , Adrian Gut , Bob Murtfeldt
发明人： Alfred E. Mann , James D. Causey, III , Alan Haubach , Luis J. Malave , John Livingston , Cliff Hague , Chad Srisathapat , Jay Yonemoto , Deborah Ruppert , Dennis P. Bishop , Adrian Gut , Bob Murtfeldt
IPC分类号： G04G15/00 , A61K9/22 , A61M5/00 , A61M5/14 , A61M5/142 , A61M5/172 , A61M5/20 , A61M5/36 , A61M5/30 , A61M37/00 , G05D6/00 , G05D7/00
CPC分类号： A61M5/1723 , A61M5/14244 , A61M5/172 , A61M5/36 , A61M2005/1402 , A61M2005/1403 , A61M2205/18 , A61M2205/3561 , A61M2205/3592 , A61M2205/505 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2209/01 , A61M2230/201 , G06F19/00 , G06F19/3468 , Y02A90/22 , Y02A90/26 , Y10S128/903
摘要： An infusion system for infusing a liquid into a body includes an external infusion device and a remote commander. The external infusion device includes a housing, a receiver, a processor and an indication device. The receiver is coupled to the housing and for receiving remotely generated commands. The processor is coupled to the housing and the receiver to receive remotely generated commands and to control the external infusion device in accordance with the commands. The indication device indicates when a command has been received and indicates when the command is being utilized to control the external infusion device so that the external infusion device is capable of being concealed from view when being remotely commanded. The remote commander includes a commander housing, a keypad for transmitting commands, and a transmitter for transmitting commands to the receiver of the external infusion device.

76. 发明授权

US06254586B1 Method and kit for supplying a fluid to a subcutaneous placement site 有权
标题翻译：用于向皮下放置位置供应流体的方法和试剂盒
公开(公告)号：US06254586B1
公开(公告)日：2001-07-03
申请号：US09395530
申请日：1999-09-14
申请人： Alfred E. Mann , John J. Mastrototaro , Clifford W. Hague
发明人： Alfred E. Mann , John J. Mastrototaro , Clifford W. Hague
IPC分类号： A61M3100
CPC分类号： A61B5/14865 , A61B5/415 , A61B5/418 , A61B5/6849 , A61M2005/1726
摘要： There is provided a method of supplying a fluid to a placement site. For instance, a sensor set is first mounted onto a skin of a user, and a placement site is contacted with the sensor set. The sensor set includes a base to secure the sensor set to the skin of the user; a cannula coupled to and extending from the base; an insertion device operatively coupled to the sensor set and the cannula to facilitate insertion of the cannula to contact the placement site; an externally extending conduit; and a sensor. The cannula has at least one lumen with an end for fluid communication with the placement site, and also has at least one port formed near another end of the lumen opposite the end for fluid communication. The conduit is in fluid communication with the at least one port of the cannula. The sensor has a sensor portion exposed by the at least one port in the at least one lumen of the cannula to determine a body characteristic of the user at the placement site. After the sensor set is mounted on the user's skin, a fluid is introduced through the externally extending conduit and the lumen to the placement site. Kits for carrying out the inventive methods are also provided.
摘要翻译：提供了将流体供应到放置位置的方法。例如，传感器组首先安装在用户的皮肤上，并且放置位置与传感器组接触。所述传感器组包括用于将所述传感器组固定到使用者皮肤的基座; 耦合到所述基座并从所述基座延伸的插管; 插入装置，其可操作地耦合到所述传感器组和所述插管，以便于套管插入以与所述放置位置接触; 外部延伸导管; 和传感器。插管具有至少一个具有端部的内腔，用于与放置位置流体连通，并且还具有至少一个端口，其形成在与端部相对的端部的另一端附近，用于流体连通。导管与套管的至少一个端口流体连通。传感器具有通过插管的至少一个内腔中的至少一个端口暴露的传感器部分，以确定放置位置处的使用者的身体特征。将传感器组安装在用户的皮肤上后，将流体通过外部延伸的管道和内腔引入到放置位置。还提供了用于实施本发明方法的试剂盒。

77. 发明授权

US6067474A Implantable device with improved battery recharging and powering configuration 失效
标题翻译：具有改进的电池充电和供电配置的可植入设备
公开(公告)号：US6067474A
公开(公告)日：2000-05-23
申请号：US126615
申请日：1998-07-31
申请人： Joseph H. Schulman , Robert Dan Dell , Alfred E. Mann , Michael A. Faltys
发明人： Joseph H. Schulman , Robert Dan Dell , Alfred E. Mann , Michael A. Faltys
IPC分类号： A61F2/02 , A61F2/18 , A61F11/00 , A61N1/08 , A61N1/36 , A61N1/375 , A61N1/378 , H01M2/10 , H01M4/02 , H01M6/10 , H01M10/04 , H01M10/34 , H01M10/46 , H02J7/00 , H02J7/02 , H02J17/00 , A61N1/34
CPC分类号： A61N1/08 , A61N1/36032 , A61N1/375 , A61N1/3787 , H01M10/0436 , H01M10/46 , H01M4/02 , H02J7/025 , H01M10/345 , H01M2/1022 , H01M2/1066 , H01M2004/025 , H01M6/10
摘要： An implantable system, such as a neural stimulator or a cochlear implant system, includes a rechargeable battery configuration having improved recharging and lifetime characteristics. The battery is housed within the implant's case and has first and second electrode plates. Each electrode plate has a plurality of slits that extend across a substantial portion of the plate's surface area. The slits in the electrode plates reduce the magnitude of eddy currents induced in the plates by external ac magnetic fields allowing faster battery recharging times. Alternatively, the electrode plates are wrapped in a spiral configuration such that, in the plane of the spiral, the electrode plates have a small cross-sectional area and no closed current loops. Additionally, the implant device may be housed in a case formed of a high-resistivity material and a circuit included in the implant device is configured to avoid large current loops that would result in eddy current heating. As a backup option, the circuitry of the implant device may optionally be powered from an external battery that inductively couples energy to the same coil that is used to charge the internal battery. In one embodiment, the implantable system is partitioned into first and second implantable cases, each having electrical circuitry therein, and only one having a rechargeable power source therein, facilitating its subsequent replacement for repair or upgrading purposes. The two cases are coupled together when the system is in use. Coupling is achieved either magnetically and/or with a detachable electrical cable. In one embodiment, power is transferred from one implant case to the other using a 3-phase transmission scheme.
摘要翻译：诸如神经刺激器或人工耳蜗植入系统的可植入系统包括具有改善的再充电和寿命特性的可再充电电池配置。电池容纳在植入物壳体内并具有第一和第二电极板。每个电极板具有延伸穿过板的表面区域的大部分的多个狭缝。电极板中的狭缝通过外部交流磁场减小板中感应的涡流的大小，从而允许更快的电池充电时间。或者，电极板被卷绕成螺旋构造，使得在螺旋的平面中，电极板具有小的横截面积并且没有闭合电流环路。另外，植入装置可以容纳在由高电阻率材料形成的壳体中，并且包括在植入装置中的电路被配置为避免将导致涡流加热的大电流环路。作为备用选项，植入装置的电路可以可选地由外部电池供电，外部电池将能量耦合到用于对内部电池充电的相同线圈。在一个实施例中，可植入系统被划分成第一和第二可植入壳体，每个壳体具有电路，并且只有一个在其中具有可再充电的电源，便于其随后的修理或升级目的的更换。当系统使用时，这两种情况耦合在一起。通过磁性和/或可拆卸电缆实现耦合。在一个实施例中，使用3相传输方案将功率从一个植入壳体传送到另一个。

78. 发明授权

US5651767A Replaceable catheter system for physiological sensors, stimulating electrodes and/or implantable fluid delivery systems 失效
标题翻译：用于生理传感器，刺激电极和/或可植入流体输送系统的可更换的导管系统
公开(公告)号：US5651767A
公开(公告)日：1997-07-29
申请号：US587881
申请日：1996-01-11
申请人： Joseph H. Schulman , Alfred E. Mann , Charles L. Byers , Jack W. Love
发明人： Joseph H. Schulman , Alfred E. Mann , Charles L. Byers , Jack W. Love
IPC分类号： A61N1/05 , A61M5/00
CPC分类号： A61N1/05 , A61B5/6865
摘要： A replaceable catheter system provides a way to replace an implantable sensor, electrode system, and/or fluid delivery/receiving system. The replaceable catheter system includes an implantable shunt, such as an arteriovenous shunt, attached to an implantable introducer. The introducer and implantable shunt are adapted for surgical implantation within a patient such that it extends from immediately below the patient's skin to the implantable shunt site. The replaceable catheter system further includes a replaceable catheter that is adapted to be contained within the introducer and properly aligned such that an implantable sensor, electrode system, and/or fluid delivery system that is carried by the replaceable catheter is placed in operative association with the implantable shunt and exposed to any fluids passing through the implantable shunt.
摘要翻译：可替换的导管系统提供了替代可植入传感器，电极系统和/或流体递送/接收系统的方法。可替换的导管系统包括可植入的分流器，例如静脉分流器，其附接到可植入导引器。导引器和可植入分流装置适于在患者体内进行手术植入，使得其从患者皮肤的正下方延伸到可植入分流部位。可替换的导管系统还包括可更换的导管，其适于容纳在导引器内并且适当对准，使得由可更换导管携带的可植入传感器，电极系统和/或流体输送系统与可植入分流器并暴露于通过可植入分流器的任何流体。

79. 发明授权

US4506679A Endocardial electrode 失效
标题翻译：心内膜电极
公开(公告)号：US4506679A
公开(公告)日：1985-03-26
申请号：US430912
申请日：1982-09-30
申请人： Alfred E. Mann
发明人： Alfred E. Mann
IPC分类号： A61N1/05 , A61N1/02
CPC分类号： A61N1/057
摘要： An improved endocardial electrode (10) of the type having an electrical conductor (14) encased in material (16) which is generally inert to body fluids and terminating at an exposed, electrically conductive tip (12). A plurality of non-conductive, resilient tines (20) extends from the encasing material (16) near the electrode tip (12). Each tine (20) forms a substantially ninety degree angle with respect to the electrical conductor (14). A blocking surface (22) is provided adjacent to a portion of each tine (20) surface facing the electrode tip (12). The blocking surface (22) allows only an upper portion of each tine to be deformed in the direction of the electrode tip (12) while allowing the entire tine to be deformed away from the electrode tip, thereby providing a decreased deformation resistance as the electrode tip (12) is inserted into a vein (34) or between heart trabeculae, and an increased deformation resistance as the electrode tip (12) is withdrawn through a vein (34) or from heart trabeculae.
摘要翻译：改进的类型的心内膜电极（10）具有被封装在材料（16）中的电导体（14），其通常对体液是惰性的并且终止于暴露的导电尖端（12）。多个不导电的弹性齿（20）从电极末端（12）附近的包裹材料（16）延伸。每个齿（20）相对于电导体（14）形成大致九十度的角度。邻近靠近电极尖端（12）的每个齿（20）表面的一部分设置阻挡表面（22）。阻挡面（22）仅允许每个齿的上部在电极末端（12）的方向上变形，同时允许整个齿从电极尖端变形，从而提供降低的变形阻力，因为电极尖端（12）插入到静脉（34）中或心脏小梁之间，并且随着电极末端（12）通过静脉（34）或心脏小梁撤出，增加的变形阻力。

80. 发明授权

US4082097A Multimode recharging system for living tissue stimulators 失效
标题翻译：用于生活组织刺激因子的多功能补充系统
公开(公告)号：US4082097A
公开(公告)日：1978-04-04
申请号：US688411
申请日：1976-05-20
申请人： Alfred E. Mann , Joseph H. Schulman
发明人： Alfred E. Mann , Joseph H. Schulman
IPC分类号： A61N1/378 , H02J7/02 , A61N1/36
CPC分类号： H02J7/025 , A61N1/3787 , H02J7/022 , Y10S320/21
摘要： A system is disclosed for controlling the charging of a rechargeable battery in an implanted human tissue stimulator by means of an external power source. Included in the stimulator are battery protection devices designed to sense the state of charge of the battery and limit the charging currrent amplitude so as not to exceed a selected maximum based on different criteria including battery state of charge signals from the implanted stimulator which are indicative of the current amplitude and battery state of charge from one of the protection devices are transmited to an external unit. Based on these signals the external unit is operated in one of a plurality of modes to cause the battery to be charged by a current with an optimum safe amplitude irrespective of determined failure of one or more of the battery protection devices.

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