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1. 发明授权

US07853033B2 Hearing aid design 失效
标题翻译：助听器设计
公开(公告)号：US07853033B2
公开(公告)日：2010-12-14
申请号：US11752196
申请日：2007-05-22
申请人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
发明人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
IPC分类号： H04R25/00
CPC分类号： H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要： A hearing aid module is shaped for insertion into a tunnel made through the soft tissue that connects the retro-auricular space with the ear canal. The hearing aid module contains a speaker or auditory transducer, a battery or other power source powering the module, signal processing circuitry, a microphone, and a hollow tube which contains a steroid or drug. Telemetry circuitry within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit. A remote control unit permits the user to make simple adjustments, such as volume and/or tone (frequency) control.
摘要翻译：助听器模块被成形为插入到通过将耳环空间与耳道连接的软组织制成的隧道中。助听器模块包含扬声器或听觉换能器，为模块供电的电池或其它电源，信号处理电路，麦克风和含有类固醇或药物的中空管。模块内的遥测电路允许使用外部编程单元对信号处理电路进行所需的频率响应或信号处理策略的编程。遥控单元允许用户进行简单的调节，例如音量和/或音调（频率）控制。

2. 发明授权

US06786860B2 Hearing aid design 失效
标题翻译：助听器设计
公开(公告)号：US06786860B2
公开(公告)日：2004-09-07
申请号：US10264962
申请日：2002-10-03
申请人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
发明人： Albert A. Maltan , Alfred E. Mann , James P. McGivern , Philip H. Lee
IPC分类号： H04R2500
CPC分类号： H04R25/505 , H04R25/554 , H04R25/558 , H04R25/60 , H04R25/65 , H04R25/658 , H04R2225/51 , H04R2225/67 , H04R2420/07
摘要： A hearing aid module (60) is shaped for insertion into a tunnel (40) made through the soft tissue that connects the retro-auricular space (50) with the ear canal (30). A hollow tube (44) may first be chronically or acutely implanted in such tunnel, and the hearing aid module inserted into the tube. The tube or hearing aid module may have a coating (45) containing a steroid or drug adapted to minimize infection and/or inflammation. The hearing aid module contains a speaker (65), a battery or other power source (66) powering the module, signal processing circuitry (67), and a microphone (63). Telemetry circuitry (69) within the module allows the signal processing circuitry to be programmed with a desired frequency response or signal processing strategy using an external programming unit (74). A remote control unit (75) permits the user to make simple adjustments, such as volume and/or tone control.
摘要翻译：助听器模块（60）被成形为用于插入通过将耳蜗空间（50）与耳道（30）连接的软组织制成的隧道（40）中。首先中空管（44）可以长期或急性地植入这样的隧道中，并且将助听器模块插入管中。管或助听器模块可以具有包含适于使感染和/或炎症最小化的类固醇或药物的涂层（45）。助听器模块包括为模块供电的扬声器（65），电池或其他电源（66），信号处理电路（67）和麦克风（63）。模块内的遥测电路（69）允许信号处理电路使用外部编程单元（74）以所需的频率响应或信号处理策略进行编程。遥控单元（75）允许用户进行简单的调节，例如音量和/或音调控制。

3. 发明授权

US08934968B2 Neurostimulation and coronary artery disease treatment 有权
标题翻译：神经刺激和冠状动脉疾病治疗
公开(公告)号：US08934968B2
公开(公告)日：2015-01-13
申请号：US11779769
申请日：2007-07-18
申请人： Todd K. Whitehurst , James R. Thacker , James P. McGivern , Kelly H. McClure
发明人： Todd K. Whitehurst , James R. Thacker , James P. McGivern , Kelly H. McClure
IPC分类号： A61N1/362 , A61N1/36 , A61M5/142
CPC分类号： A61N1/36114 , A61M5/14276 , A61M2205/054 , A61M2205/3523 , A61M2205/8206 , A61M2230/06
摘要： A method for treating a patient may include treating coronary artery disease in combination with angina pectoris and/or the control of angina pain by delivering chemical and/or electrical stimulation pulses to the cardiac and/or nervous tissue of the patient in a coordinated manner. A system for treating a patient suffering from coronary artery disease and angina may include a stimulator that generates at least one pulse in accordance with prescribed parameters, a catheter, a lead, and/or a sensor.
摘要翻译：用于治疗患者的方法可以包括通过以协调的方式将化学和/或电刺激脉冲递送到患者的心脏和/或神经组织来治疗与心绞痛联合的冠状动脉疾病和/或控制心绞痛。用于治疗患有冠状动脉疾病和心绞痛的患者的系统可以包括根据规定参数产生至少一个脉冲的刺激器，导管，引线和/或传感器。

4. 发明授权

US08712547B2 Cavernous nerve stimulation via unidirectional propagation of action potentials 有权
标题翻译：通过动作电位的单向传播进行海绵体神经刺激
公开(公告)号：US08712547B2
公开(公告)日：2014-04-29
申请号：US13036278
申请日：2011-02-28
申请人： Todd K. Whitehurst , James P. McGivern , Rafael Carbunaru , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley
发明人： Todd K. Whitehurst , James P. McGivern , Rafael Carbunaru , Matthew I. Haller , Tom Xiaohai He , Kerry Bradley
IPC分类号： A61N1/05 , A61N1/372
CPC分类号： A61N1/0556 , A61N1/0551 , A61N1/36071 , A61N1/37205
摘要： An implantable stimulation device includes a device body; at least one set of partitioned electrodes disposed on a portion of the device body and configured and arranged for application of electrical stimulation to adjacent tissue; and insulating material separating the partitioned electrodes from each other. Each set of partitioned electrodes includes a plurality of partitioned electrodes disposed around a circumference of the device body. The implantable stimulation device can be configured and arranged so that each of the partitioned electrodes is independently programmable.
摘要翻译：可植入刺激装置包括装置主体; 至少一组分隔电极，其设置在所述装置主体的一部分上，并被配置和布置成用于对相邻组织施加电刺激; 以及将分隔电极彼此分离的绝缘材料。每组分隔电极包括围绕装置主体的圆周设置的多个分隔电极。可植入式刺激装置可以被配置和布置成使得每个分隔电极可独立编程。

5. 发明授权

US08364278B2 Lead assembly for implantable microstimulator 有权
标题翻译：可植入微型激励器的导线组件
公开(公告)号：US08364278B2
公开(公告)日：2013-01-29
申请号：US10503281
申请日：2003-01-29
申请人： Anne M. Pianca , Todd K. Whitehurst , James P. McGivern
发明人： Anne M. Pianca , Todd K. Whitehurst , James P. McGivern
IPC分类号： A61N1/05
CPC分类号： H01R43/16 , A61N1/05 , H01R13/5224 , Y10T29/49204
摘要： A lead assembly for a small implantable medical device connects a remote electrode to a microdevice and inhibits fluid ingress into the connection. Microdevices may provide either or both tissue stimulation and sensing. Known microdevices include spaced apart electrodes on the outer surface of the microdevice. The lead assembly includes an insulated lead including a proximal end and a distal end, with at least one conductor therebetween; at least one electrode at the distal end of the lead and electrically connected to the at least one conductor, and a connector attached to the proximal end of the lead and adapted to be removably connectable to the microdevice. The connector includes at least one contact to electrically connect at least one device electrode on the microdevice to the at least one conductor. The lead assembly is configured to inhibit fluid ingress into the connector.
摘要翻译：用于小型可植入医疗装置的引导组件将远程电极连接到微型装置并且阻止流体进入连接。微器件可以提供组织刺激和感测之一或两者。已知的微器件在微器件的外表面上包括间隔开的电极。引线组件包括绝缘引线，其包括近端和远端，其间具有至少一个导体; 在所述引线的远端处的至少一个电极并且电连接到所述至少一个导体，以及连接到所述引线的近端并适于可移除地连接到所述微器件的连接器。所述连接器包括至少一个接触件，以将所述微器件上的至少一个器件电极电连接到所述至少一个导体。引线组件被配置为抑制流体进入连接器。

6. 发明授权

US06901296B1 Methods and systems for direct electrical current stimulation as a therapy for cancer and other neoplastic diseases 有权
标题翻译：直接电流刺激作为癌症和其他肿瘤疾病治疗的方法和系统
公开(公告)号：US06901296B1
公开(公告)日：2005-05-31
申请号：US10133768
申请日：2002-04-26
申请人： Todd K. Whitehurst , James P. McGivern , Janusz A. Kuzma
发明人： Todd K. Whitehurst , James P. McGivern , Janusz A. Kuzma
IPC分类号： A61N1/08 , A61N1/10 , A61N1/20 , A61N1/372
CPC分类号： A61N1/205 , A61N1/08 , A61N1/37205
摘要： A small implantable stimulator(s) includes at least two electrodes for delivering electrical stimulation to surrounding tissue. The small stimulator provides means of stimulating a neoplasm with direct electrical current, such as relatively low-level direct current, without the need for external appliances during the stimulation session. The stimulator may be configured to be small enough to be implanted entirely within a neoplasm. Open- and closed-loop systems are disclosed.
摘要翻译：一个小的植入式刺激器包括至少两个用于向周围组织传递电刺激的电极。小的刺激器提供了用直接电流刺激肿瘤的手段，例如相对低的直流电流，而不需要在刺激期间的外部器具。刺激器可以被配置为足够小以完全植入肿瘤内。公开了开环和闭环系统。

7. 发明授权

US06650943B1 Fully implantable neurostimulator for cavernous nerve stimulation as a therapy for erectile dysfunction and other sexual dysfunction 有权
标题翻译：用于海绵神经刺激的完全植入式神经刺激器作为勃起功能障碍和其他性功能障碍的治疗方法
公开(公告)号：US06650943B1
公开(公告)日：2003-11-18
申请号：US09799988
申请日：2001-03-06
申请人： Todd K. Whitehurst , James P. McGivern
发明人： Todd K. Whitehurst , James P. McGivern
IPC分类号： A61N136
CPC分类号： A61N1/372 , A61N1/36007 , A61N1/37205
摘要： An implantable stimulator(s) with at least two electrodes, which is small enough to have the electrodes located adjacent to a cavernous nerve(s) or other nerve(s) innervating the reproductive organs, uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a battery is accomplished, for example, by inductive coupling with an external appliance. The small stimulator provides means of stimulating a nerve(s) when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power. In a preferred embodiment, the system is capable of open-and closed-loop operation. In closed-loop operation, at least one implant includes a sensor, and the sensed condition is used to adjust stimulation parameters.
摘要翻译：具有至少两个电极的可植入刺激器，其足够小以使电极位于邻近海绵状神经或支配生殖器官的其他神经，使用电源/存储装置，例如可充电电池这种电池的定期再充电例如通过与外部电器的感应耦合来实现。小刺激器提供在需要时刺激神经的手段，而不需要在刺激期间的外部器具。必要时，外部设备用于传送和/或从刺激器传输数据和传输电力。在优选实施例中，系统能够进行开环和闭环操作。在闭环操作中，至少一个植入物包括传感器，并且所使用的感测条件用于调节刺激参数。

8. 发明授权

US4591940A Signal quality monitor for protective relay system 失效
标题翻译：保护继电器系统的信号质量监控
公开(公告)号：US4591940A
公开(公告)日：1986-05-27
申请号：US682403
申请日：1984-12-17
申请人： Shan C. Sun , James P. McGivern
发明人： Shan C. Sun , James P. McGivern
IPC分类号： H02H1/00 , H02H3/00
CPC分类号： H02H1/0084
摘要： A signal quality monitor, and a protective relay system using the monitor, which utilizes both AC and DC signals from the receiver agc stage to monitor a plurality of different signal parameters. A signal responsive to the noise in the communication channel which transmits at least one of the protective relay signals used in a protective relay comparison function, is also used in the trip circuits of the associated circuit interrupter to continuously adapt or modify the trip level in response to channel noise.
摘要翻译：信号质量监视器和使用监视器的保护继电器系统，其利用来自接收器agc级的AC和DC信号来监测多个不同的信号参数。响应于在通信信道中发送保护继电器比较功能中使用的保护继电器信号中的至少一个的通信信道的信号也被用于相关联的电路断续器的跳闸电路中，以响应于连续地适应或修改跳闸电平通道噪声。

9. 发明授权

US08588917B2 Fully implantable neurostimulator for autonomic nerve fiber stimulation as a therapy for urinary and bowel dysfunction 失效
标题翻译：用于自主神经纤维刺激的完全植入式神经刺激器作为尿和肠功能障碍的治疗
公开(公告)号：US08588917B2
公开(公告)日：2013-11-19
申请号：US13493753
申请日：2012-06-11
申请人： Todd K. Whitehurst , James P. McGivern , Carla M. Mann
发明人： Todd K. Whitehurst , James P. McGivern , Carla M. Mann
IPC分类号： A61N1/00 , A61B5/103
CPC分类号： A61N1/36007
摘要： An implantable stimulator(s), small enough to be located near or adjacent to an autonomic nerve(s) innervating urinary and/or gastrointestinal structures, uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a power source/storage device is accomplished, for example, by inductive coupling with an external appliance. The small stimulator provides a means of stimulating a nerve(s) or other tissue when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power, if necessary. In a preferred embodiment, the system is capable of open- and closed-loop operation. In closed-loop operation, at least one implant includes at least one sensor, and the sensed condition is used to adjust stimulation parameters.
摘要翻译：小到足以位于支配尿和/或胃肠结构的自主神经附近或邻近的可植入刺激器使用诸如可再充电电池的电源/存储装置。这样的电源/存储装置的定期再充电例如通过与外部电器的感应耦合来实现。小刺激器提供了在需要时刺激神经或其他组织的手段，而不需要在刺激期间的外部器具。必要时，如果需要，外部设备用于向刺激器传送数据和/或从刺激器传输数据。在优选实施例中，系统能够进行开环和闭环操作。在闭环操作中，至少一个植入物包括至少一个传感器，并且所感测到的条件用于调整刺激参数。

10. 发明授权

US08554342B2 Neural stimulation lead fixation 失效
标题翻译：神经刺激铅固定
公开(公告)号：US08554342B2
公开(公告)日：2013-10-08
申请号：US13620138
申请日：2012-09-14
申请人： James R. Thacker , Michael S. Colvin , David K. L. Peterson , James P. McGivern
发明人： James R. Thacker , Michael S. Colvin , David K. L. Peterson , James P. McGivern
IPC分类号： A61N1/05
CPC分类号： A61N1/0558 , A61M25/1002 , A61M25/1011
摘要： An implantable lead having at least one electrode contact at or near its distal end prevents undesirable movement of the electrode contact from its initial implant location. One embodiment relates to a spinal cord stimulation (SCS) lead. A first injectable material is injected into the dura space to mechanically position the electrode array with respect to the spinal cord. Conjunctively for use with adhesives, or alternatively for use instead of the adhesives, a balloon may be positioned on the electrode lead array. The balloon is filled with air, liquid or a compliant material. When inflated, the balloon stabilizes the lead with respect to the spinal cord and holds the lead in place. An elastic aspect of the balloon serves as an internal contained relief valve to limit the pressure the balloon may place on the surrounding tissues when the epidural space is constrained.
摘要翻译：具有在其远端处或其远端处具有至少一个电极接触的可植入引线防止电极接触件从其初始植入位置的不期望的移动。一个实施方案涉及脊髓刺激（SCS）引线。将第一可注射材料注入硬脑膜空间以相对于脊髓机械地定位电极阵列。结合使用粘合剂，或代替粘合剂代替使用，球囊可以位于电极引线阵列上。气球充满空气，液体或柔顺材料。当膨胀时，气囊相对于脊髓稳定铅，并将铅保持在适当位置。气囊的弹性方面用作内部包含的安全阀，以限制当硬膜外腔被约束时球囊可能在周围组织上的压力。

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