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61. 发明申请

US20100315191A1 Patterned magnetic inductors 审中-公开
标题翻译：图案磁感应器
公开(公告)号：US20100315191A1
公开(公告)日：2010-12-16
申请号：US11580798
申请日：2006-10-13
申请人： T. Danny Xiao , Xinqing Ma , Steve Murphy
发明人： T. Danny Xiao , Xinqing Ma , Steve Murphy
IPC分类号： H01F5/00 , H01F7/06
CPC分类号： H01F1/33 , B82Y25/00 , H01F1/0054 , H01F1/344 , H01F41/046 , H01F41/16 , H01F41/20 , H01F41/22 , H01F41/26 , H01F41/30 , H01F2017/0066 , H05B2214/04 , Y10T29/4902 , Y10T29/49075
摘要： A patterned inductor includes a conductive path and a nanostructured magnetic composition deposited on the conductive path. The magnetic composition can be screen printed, inkjetted, electrodeposited, spin coated, physical vapor deposited, or chemical vapor deposited onto the conductive path.
摘要翻译：图案化电感器包括导电路径和沉积在导电路径上的纳米结构磁性组合物。磁性组合物可以丝网印刷，喷墨，电沉积，旋涂，物理气相沉积或化学气相沉积到导电路径上。

62. 发明申请

US20100279024A1 REPROGRAMMABLE PARALLEL NANOMANUFACTURING 有权
标题翻译：可再生平行纳米生物学
公开(公告)号：US20100279024A1
公开(公告)日：2010-11-04
申请号：US12376646
申请日：2007-10-01
申请人： Thomas M. Crawford
发明人： Thomas M. Crawford
IPC分类号： B05D3/06 , B05D3/00 , B05D1/00
CPC分类号： H01F1/0063 , B82Y25/00 , B82Y30/00 , H01F1/0054 , H01F1/111
摘要： A method of producing a nanoscale structure having substantially immobilized nanoparticles arranged at a predetermined patterned is generally disclosed. First, a curable polymeric solution is placed within a well defined by a wafer. The curable polymeric solution includes a curable polymeric material and a magnetically coated nanoparticle. The well is positioned adjacent to an atomically-smooth medium. A recording head is moved in a predetermined manner to produce a magnetic field profile that substantially immobilizes the magnetically coated nanoparticle within the curable polymeric solution in the well. The curable polymeric solution is cured such that the magnetically coated nanoparticle remains substantially immobilized after the magnetic field profile is removed.
摘要翻译：通常公开了一种制备具有以预定图案化布置的基本上固定的纳米级纳米尺度结构的方法。首先，将可固化的聚合物溶液放置在由晶片限定的阱内。可固化的聚合物溶液包括可固化的聚合物材料和磁性涂覆的纳米颗粒。井与原子光滑介质相邻。记录头以预定的方式移动以产生磁场分布，其基本上将磁性涂覆的纳米颗粒固定在井中的可固化聚合物溶液中。固化的聚合物溶液被固化，使得在除去磁场分布之后，磁性涂覆的纳米颗粒保持基本上固定。

63. 发明授权

US07807217B2 Method of producing self-assembled cubic FePt nanoparticles and apparatus using same 有权
标题翻译：自组装立方FePt纳米粒子的制备方法及其使用方法
公开(公告)号：US07807217B2
公开(公告)日：2010-10-05
申请号：US11481388
申请日：2006-07-05
申请人： Nisha Shukla , Timothy John Klemmer , Dieter Klaus Weller , Chao Liu
发明人： Nisha Shukla , Timothy John Klemmer , Dieter Klaus Weller , Chao Liu
IPC分类号： B05D1/12
CPC分类号： G11B5/653 , B22F1/0022 , B22F9/24 , B22F2001/0037 , B82Y30/00 , G11B5/65 , H01F1/0054 , H01F1/065 , H01F10/123 , H01F10/265
摘要： A method comprises: heating a solution of platinum acetylacetonate, Fe(CO)5, oleic acid, and oleylamine in dichlorobenzene to a reflux temperature, refluxing the solution, and using the solution to deposit FePt nanoparticles. A magnetic storage medium that includes cubic FePt particles is also provided.
摘要翻译：一种方法包括：将乙酰丙酮酸铂，Fe（CO）5，油酸和油胺在二氯苯中的溶液加热至回流温度，回流该溶液，并使用该溶液沉积FePt纳米颗粒。还提供了包括立方FePt颗粒的磁存储介质。

64. 发明授权

US07781078B2 Method and system for magnetic recording using self-organized magnetic nanoparticles 失效
标题翻译：使用自组织磁性纳米粒子的磁记录方法和系统
公开(公告)号：US07781078B2
公开(公告)日：2010-08-24
申请号：US12241509
申请日：2008-09-30
申请人： Rene J. M. van de Veerdonk , Xiaowei Wu , Dieter K. Weller
发明人： Rene J. M. van de Veerdonk , Xiaowei Wu , Dieter K. Weller
IPC分类号： G11B5/65 , G11B5/712
CPC分类号： B82Y25/00 , B82Y10/00 , G11B5/00 , G11B5/012 , G11B5/02 , G11B5/09 , G11B5/127 , G11B5/17 , G11B5/33 , G11B5/70605 , G11B5/712 , G11B5/714 , G11B5/74 , G11B5/743 , G11B5/82 , G11B11/002 , G11B11/03 , G11B2005/0002 , G11B2005/0005 , G11B2005/0021 , H01F1/0054 , H01F1/009 , H01F1/068 , Y10T428/24942 , Y10T428/25 , Y10T428/2991 , Y10T428/2995 , Y10T428/2998
摘要： A method and system for magnetic recording using self-organized magnetic nanoparticles is disclosed. The method may include depositing surfactant coated nanoparticles on a substrate, wherein the surfactant coated nanoparticles represent first bits of recorded information. The surfactant coating is then removed from selected of the surfactant coated nanoparticles. The selected nanoparticles with their surfactant coating removed may then be designated to represent second bits of recorded information. The surfactant coated nanoparticles have a first saturation magnetic moment and the selected nanoparticles with the surfactant coating removed have a second saturation magnetic moment. Therefore, by selectively removing the surfactant coating from certain nanoparticles, a write operation for recording the first and second bits of information may be performed. A read operation may be carried out by detecting the different magnetic moments of the surfactant coated nanoparticles and the non-surfactant coated nanoparticles.
摘要翻译：公开了一种使用自组织磁性纳米颗粒进行磁记录的方法和系统。该方法可以包括在衬底上沉积表面活性剂涂覆的纳米颗粒，其中表面活性剂涂覆的纳米颗粒表示记录信息的第一位。然后从选择的表面活性剂涂覆的纳米颗粒中除去表面活性剂涂层。然后将其去除其表面活性剂涂层的所选择的纳米颗粒指定为表示记录信息的第二位。表面活性剂涂覆的纳米颗粒具有第一饱和磁矩，并且去除了表面活性剂涂层的所选纳米颗粒具有第二饱和磁矩。因此，通过从某些纳米颗粒中选择性地去除表面活性剂涂层，可以执行用于记录信息的第一和第二位的写入操作。可以通过检测表面活性剂涂覆的纳米颗粒和非表面活性剂涂覆的纳米颗粒的不同磁矩来进行读取操作。

65. 发明申请

US20100143263A1 MAGNETIC RESONANCE IMAGING CONTRAST AGENTS COMPRISING ZINC-CONTAINING MAGNETIC METAL OXIDE NANOPARTICLES 有权
标题翻译：包含含锌金属氧化物纳米粒子的磁共振成像对比剂
公开(公告)号：US20100143263A1
公开(公告)日：2010-06-10
申请号：US12527482
申请日：2008-04-11
申请人： Jinwoo Cheon , Young-wook Jun , Jung-tak Jang
发明人： Jinwoo Cheon , Young-wook Jun , Jung-tak Jang
IPC分类号： A61K49/06 , C01G9/02
CPC分类号： A61K49/1875 , A61K49/1836 , A61K49/1863 , A61K49/1866 , A61K49/1869 , B82Y5/00 , B82Y25/00 , C01G49/0063 , C01G49/009 , C01P2002/72 , C01P2002/85 , C01P2004/04 , C01P2006/42 , H01F1/0054 , Y10S977/773 , Y10S977/93
摘要： The present invention relates to an MRI contrast agent that includes zinc-containing water-soluble metal oxide nanoparticles and has an improved contrast effect. The zinc-containing water-soluble metal oxide nanoparticles are characterized by addition of zinc to a matrix comprising the metal oxide nanoparticles or by substitution of metal in the matrix, resulting in the improved contrast effect of MRI. In addition, the zinc-containing metal oxide nanoparticles of the present invention include the MRI contrast agent t having hybrid structures of “zinc-containing metal oxide nanoparticle—biologically/chemically active material” in which the nanoparticle is conjugated with a bioactive material such as proteins, antibodies, and chemical materials.
摘要翻译：本发明涉及包含含锌水溶性金属氧化物纳米粒子并具有改善的对比效果的MRI造影剂。含锌水溶性金属氧化物纳米颗粒的特征在于将锌添加到包含金属氧化物纳米颗粒的基质中或通过置换基质中的金属，导致MRI的对比度改善。此外，本发明的含锌金属氧化物纳米颗粒包括具有“含锌金属氧化物纳米颗粒 - 生物/化学活性材料”的混合结构的MRI造影剂t，其中纳米颗粒与生物活性材料如蛋白质，抗体和化学物质。

66. 发明申请

US20100123456A1 METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION, MAGNETIC PARTICLES AND THE USE OF MAGNETIC PARTICLES 有权
标题翻译：在动作区域，磁性颗粒和磁性颗粒的使用中影响和/或检测磁性颗粒的方法
公开(公告)号：US20100123456A1
公开(公告)日：2010-05-20
申请号：US12523548
申请日：2008-01-18
申请人： Hans M. Boeve , Denis Markov
发明人： Hans M. Boeve , Denis Markov
IPC分类号： G01R33/12 , H01F1/04 , G01N33/553 , G01N33/573
CPC分类号： A61B5/05 , A61B5/0515 , A61K49/1818 , A61K49/1869 , B82Y25/00 , H01F1/0054 , H01F1/344
摘要： A method for influencing and/or detecting magnetic particles in a region of action, magnetic particles and the use of magnetic particles is disclosed, which method comprises the steps of: —introducing magnetic particles into a region of action, —generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action —changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles change locally, —acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the magnetic particles comprise a core region and a shell region, the core region comprising a magnetic material, wherein the magnetic material of the core region is provided as a mainly metallic material of comparably high saturation magnetization, wherein the shell region comprises mainly a metal oxide material or a noble metal material.
摘要翻译：公开了一种用于影响和/或检测磁性颗粒的作用区域，磁性颗粒和使用磁性颗粒的方法，该方法包括以下步骤： - 将磁性颗粒引入作用区域，产生磁选择场具有其磁场强度的空间中的图案，使得具有低磁场强度的第一子区域和具有较高磁场强度的第二子区域在动作区域中形成，该位置改变位于通过磁驱动场在动作区域中的两个子区域，使得磁性颗粒的磁化在局部变化， - 信号，该信号取决于作用区域中的磁化，该磁化受到变化的影响在第一和第二子区域的空间中的位置，其中磁性颗粒包括芯区域和壳体区域，芯区域包括磁性配合物其中芯区的磁性材料被提供为具有相当高的饱和磁化强度的主要金属材料，其中壳区主要包括金属氧化物材料或贵金属材料。

67. 发明申请

US20100113861A1 METALLIC NANOPARTICLES WITH COATED SHELLS AND APPLICATIONS OF SAME 审中-公开
标题翻译：具有涂层的金属纳米颗粒及其应用
公开(公告)号：US20100113861A1
公开(公告)日：2010-05-06
申请号：US12606958
申请日：2009-10-27
申请人： Alexandru S. Biris , Yang Xu , Zhongrui Li , Alexandru R. Biris
发明人： Alexandru S. Biris , Yang Xu , Zhongrui Li , Alexandru R. Biris
IPC分类号： A61N2/00 , B32B5/00 , H01F1/01 , A61K49/06 , A61K9/14 , A61K38/02 , A61K39/395 , A61K31/7052
CPC分类号： A61K9/141 , A61K9/0009 , A61K9/5115 , A61K41/0052 , A61K51/02 , A61N1/406 , A61N5/0601 , A61N5/062 , B82Y25/00 , H01F1/0054 , Y10T428/2991 , Y10T428/2998
摘要： A process or method for treating cancer. In one embodiment, the method includes the steps of providing a plurality of metallic nanoparticles, wherein each of the plurality of metallic nanoparticles has a core formed with a first metallic material, and a shell formed with a non-metallic material containing carbon, and wherein the shell is formed to enclose the metallic core completely, introducing said metallic nanoparticles into a mammal such that said metallic nanoparticles selectively target at least one type of cancerous cell, and subsequently applying at least one radio frequency of electromagnetic waves to said mammal for a period of time effective to induce skin currents in the cores of the first metallic material of said metallic nanoparticles to cause heat generated locally around targeted at least one type of cancerous cell to kill said cancerous cell.
摘要翻译：用于治疗癌症的方法或方法。在一个实施方案中，该方法包括提供多个金属纳米颗粒的步骤，其中多个金属纳米颗粒中的每一个具有形成有第一金属材料的芯和由含有碳的非金属材料形成的壳，并且其中壳体被形成为完全包围金属芯，将所述金属纳米颗粒引入到哺乳动物中，使得所述金属纳米粒子选择性地靶向至少一种类型的癌细胞，并且随后向所述哺乳动物施加至少一个电磁波射频一段时间的时间有效地诱导所述金属纳米颗粒的第一金属材料的芯中的皮肤电流，以引起局部周围的靶向至少一种类型的癌细胞杀死所述癌细胞的热。

68. 发明授权

US07691285B2 Magnetic nanoparticles having improved magnetic properties 失效
标题翻译：具有改善磁性能的磁性纳米颗粒
公开(公告)号：US07691285B2
公开(公告)日：2010-04-06
申请号：US10564228
申请日：2004-07-09
申请人： Joachim Teller , Fritz Westphal , Cordula Gruettner
发明人： Joachim Teller , Fritz Westphal , Cordula Gruettner
IPC分类号： H01F1/00
CPC分类号： A61K33/26 , A61K47/60 , A61K47/61 , A61K47/6849 , A61K47/6923 , A61K47/6929 , A61K49/186 , A61K49/1863 , A61K49/1875 , A61K51/1255 , B82Y5/00 , B82Y25/00 , H01F1/0054 , H01F1/445 , Y10S977/811 , Y10S977/83 , Y10S977/838
摘要： The invention relates to a method for producing magnetic nanoparticles which are made of metal oxide-polymer composites and are provided with an increased magnetic mobility, among other things, due the high metal oxide content and the morphological structure thereof. High-pressure homogenization has proven to be a reliable technique for producing the inventive magnetic nanoparticles. According to said technique, the components metal oxide and polymer are processed in a carrier medium. Water is used in most cases at pressures ranging from 500 bar to 1200 bar while using great shearing forces. High pressure homogenization creates a colloidally stable magnetic particle population having a diameter ranging below 200 nm while also resulting in the produced magnetic nanoparticles being provided with greater magnetic moments than the metal oxide used as an initial material at low magnetic field strengths. The inventive particles are particularly suitable for applications in the bioanalytical and diagnostic field, in bioseparation processes, and as a carrier material in high throughput screening.
摘要翻译：本发明涉及一种由金属氧化物 - 聚合物复合材料制成的磁性纳米颗粒的制造方法，其特征在于由于高的金属氧化物含量及其形态结构而具有增加的磁性迁移率。已经证明高压均质化是生产本发明磁性纳米颗粒的可靠技术。根据所述技术，组分金属氧化物和聚合物在载体介质中加工。大多数情况下，在500 bar至1200 bar的压力下使用水，同时使用极大的剪切力。高压均质化产生直径在200nm以下的胶体稳定的磁性粒子群，同时还使得所制备的磁性纳米粒子具有比在低磁场强度下用作初始材料的金属氧化物更大的磁矩。本发明的颗粒特别适用于生物分析和诊断领域，生物分离过程中的应用，以及高通量筛选中的载体材料。

69. 发明授权

US07682838B2 Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules 有权
标题翻译：磁性纳米颗粒，磁性检测器阵列及其用于检测生物分子的方法
公开(公告)号：US07682838B2
公开(公告)日：2010-03-23
申请号：US11938187
申请日：2007-11-09
申请人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
发明人： Shan X. Wang , Robert L. White , Chris D. Webb , Guanxiong Li
IPC分类号： G01N33/543 , G01N1/36
CPC分类号： H01F10/3272 , B01J2219/00378 , B01J2219/00497 , B01J2219/00563 , B01J2219/00585 , B01J2219/00596 , B01J2219/00653 , B01J2219/00655 , B01J2219/00677 , B01J2219/00722 , B01J2219/00725 , B01J2219/00734 , B01L3/5027 , B82Y5/00 , B82Y15/00 , B82Y25/00 , B82Y30/00 , C12Q1/6834 , C40B40/06 , C40B40/10 , C40B40/14 , C40B60/14 , C40B70/00 , G01N33/54326 , G01N33/5434 , G01N33/553 , G01N2446/10 , H01F1/0054 , H01F10/3254 , Y10T428/2991 , C12Q2563/143
摘要： Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.
摘要翻译：公开了磁性纳米颗粒及其用于检测生物分子的方法。磁性纳米颗粒可以连接到核酸分子，然后通过与检测器（例如自旋阀检测器或磁性隧道结检测器）连接的互补序列捕获。可以以高特异性和灵敏度实现结合的磁性纳米颗粒的检测。

70. 发明申请

US20100047579A1 COATED, FINE METAL PARTICLES AND THEIR PRODUCTION METHOD 有权
标题翻译：涂层，精细金属颗粒及其生产方法
公开(公告)号：US20100047579A1
公开(公告)日：2010-02-25
申请号：US12442047
申请日：2007-09-18
申请人： Hisato Tokoro , Shigeo Fujii , Takashi Nakabayashi
发明人： Hisato Tokoro , Shigeo Fujii , Takashi Nakabayashi
IPC分类号： B32B1/00 , B05D3/02
CPC分类号： G11B5/712 , B22F1/02 , B22F9/20 , B82Y25/00 , C22C33/0235 , G01N33/553 , H01F1/0054 , H01F1/33 , Y10T428/2991 , Y10T428/2993
摘要： A method for producing coated, fine metal particles comprising the steps of mixing powder comprising TiC and TiN with powder of an oxide of a metal M meeting the relation of ΔGM-O>ΔGTiO2, wherein ΔGM-O represents the standard free energy of formation of metal M oxide, and heat-treating the resultant mixed powder in a non-oxidizing atmosphere to reduce the oxide of the metal M with the powder comprising TiC and TiN, while coating the resultant metal M particles with Ti oxide, and coated, fine metal particles each comprising a metal core particle and a Ti oxide coating and having a carbon content of 0.2-1.4% by mass and a nitrogen content of 0.01-0.2% by mass.
摘要翻译：一种制备涂覆的金属微粒的方法，包括以下步骤：将包含TiC和TiN的粉末与满足以下关系的金属M的氧化物粉末混合;其中＆Dgr; GMi代表标准形成金属M氧化物的自由能，并且在非氧化气氛中对所得混合粉末进行热处理，以用包含TiC和TiN的粉末来还原金属M的氧化物，同时用Ti氧化物涂覆所得金属M颗粒和包含金属核粒子和Ti氧化物被膜，碳含量为0.2〜1.4质量％，氮含量为0.01〜0.2质量％的金属微粒子。

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