专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

61. 发明授权

US06451830B1 Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity 失效
标题翻译：取代的N，N-二取代的非稠合杂环氨基化合物用于抑制胆固醇酯转移蛋白活性的用途
公开(公告)号：US06451830B1
公开(公告)日：2002-09-17
申请号：US09991085
申请日：2001-11-14
申请人： James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
发明人： James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
IPC分类号： A61K31421
CPC分类号： C07C323/25 , B01D2201/345 , C07B2200/07 , C07C215/08 , C07C215/16 , C07C217/58 , C07C217/84 , C07C217/88 , C07C217/90 , C07C217/92 , C07C219/06 , C07C219/28 , C07C219/34 , C07C225/22 , C07C229/38 , C07C229/52 , C07C229/60 , C07C233/25 , C07C233/43 , C07C233/69 , C07C233/80 , C07C235/20 , C07C235/24 , C07C235/56 , C07C237/30 , C07C237/38 , C07C255/13 , C07C255/21 , C07C255/24 , C07C255/54 , C07C255/58 , C07C271/28 , C07C275/34 , C07C275/40 , C07C311/21 , C07C311/58 , C07C317/32 , C07C317/36 , C07C323/19 , C07C323/20 , C07C323/31 , C07C323/32 , C07C323/37 , C07C323/44 , C07C323/65 , C07C327/30 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2603/18 , C07D207/335 , C07D209/82 , C07D213/38 , C07D213/62 , C07D225/08 , C07D239/26 , C07D239/34 , C07D251/46 , C07D257/04 , C07D263/04 , C07D265/14 , C07D295/088 , C07D295/108 , C07D295/135 , C07D295/192 , C07D307/04 , C07D307/38 , C07D333/20 , C07D333/28 , C07D491/10
摘要： The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted non-fused heterocyclo amines. A preferred specific N,N-disubstituted non-fused heterocyclo amine is the compound:
摘要翻译：本发明涉及可用作胆固醇酯转移蛋白（CETP;血浆脂质转移蛋白-1）的抑制剂的取代多环芳基和杂芳基叔杂烷基胺化合物的用途以及用于治疗动脉粥样硬化和其它冠状动脉疾病的化合物，组合物和方法。优选的叔杂烷基胺化合物是取代的N，N-二取代的非稠合杂环胺。优选的具体的N，N-二取代的非稠合杂环胺是化合物：

62. 发明授权

US06451823B1 Use of substituted N-phenoxy-N-phenyl aminoalcohol compounds for inhibiting cholesteryl ester transfer protein activity 失效
标题翻译：使用取代的N-苯氧基-N-苯基氨基醇化合物抑制胆固醇酯转移蛋白活性
公开(公告)号：US06451823B1
公开(公告)日：2002-09-17
申请号：US09990645
申请日：2001-11-14
申请人： James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
发明人： James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
IPC分类号： C07C23300
CPC分类号： C07C323/25 , B01D2201/345 , C07B2200/07 , C07C215/08 , C07C215/16 , C07C217/58 , C07C217/84 , C07C217/88 , C07C217/90 , C07C217/92 , C07C219/06 , C07C219/28 , C07C219/34 , C07C225/22 , C07C229/38 , C07C229/52 , C07C229/60 , C07C233/25 , C07C233/43 , C07C233/69 , C07C233/80 , C07C235/20 , C07C235/24 , C07C235/56 , C07C237/30 , C07C237/38 , C07C255/13 , C07C255/21 , C07C255/24 , C07C255/54 , C07C255/58 , C07C271/28 , C07C275/34 , C07C275/40 , C07C311/21 , C07C311/58 , C07C317/32 , C07C317/36 , C07C323/19 , C07C323/20 , C07C323/31 , C07C323/32 , C07C323/37 , C07C323/44 , C07C323/65 , C07C327/30 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2603/18 , C07D207/335 , C07D209/82 , C07D213/38 , C07D213/62 , C07D225/08 , C07D239/26 , C07D239/34 , C07D251/46 , C07D257/04 , C07D263/04 , C07D265/14 , C07D295/088 , C07D295/108 , C07D295/135 , C07D295/192 , C07D307/04 , C07D307/38 , C07D333/20 , C07D333/28 , C07D491/10
摘要： The invention relates to use of substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N-phenoxy-N-phenyl aminoalcohols. A preferred specific N-phenoxy-N-phenyl aminoalcohol is the compound:
摘要翻译：本发明涉及可用作胆固醇酯转移蛋白（CETP;血浆脂质转移蛋白-1）的抑制剂的取代多环芳基和杂芳基叔杂烷基胺化合物的用途以及用于治疗动脉粥样硬化和其它冠状动脉疾病的化合物，组合物和方法。优选的叔杂烷基胺化合物是取代的N-苯氧基-N-苯基氨基醇。优选的特定N-苯氧基-N-苯基氨基醇是化合物：

63. 发明授权

US06440999B1 Intimal thickening inhibitory agent 失效
标题翻译：内膜增厚抑制剂
公开(公告)号：US06440999B1
公开(公告)日：2002-08-27
申请号：US09637022
申请日：2000-08-14
申请人： Osamu Cynshi , Reiko Sekimori , Yoshiaki Kato
发明人： Osamu Cynshi , Reiko Sekimori , Yoshiaki Kato
IPC分类号： A01N4312
CPC分类号： C07C323/20 , C07C43/23 , C07C317/22
摘要： An intimal thickening inhibitory agent comprising, as an active ingredient, a compound represented by formula (1): wherein x represents an oxygen atom or a group of formula (2) —S—(O)n (2) wherein n represents an integer of from 0 to 2, R1 represents a hydrogen atom or an acyl group; R2 represents a hydrogen atom, a lower alkyl group or a lower alkenyl group; R3 represents a lower alkyl group; and R4, R5, and R6, which may be the same or different, each represent a hydrogen atom or a substituted or unsubstituted alkyl group; or R3 and R4 may be taken together to form a 5-membered ring; or R5 and R6 may be taken together to form a cycloalkyl group; provided that R6 is nil when R3 and R4 are taken together to form benzofuran or benzo[b]thiophene.
摘要翻译：一种内膜增稠抑制剂，其包含作为活性成分的由式（1）表示的化合物：其中x表示氧原子或式（2）的基团，其中n表示0至2的整数，R 1表示氢原子或酰基; R2表示氢原子，低级烷基或低级烯基; R3表示低级烷基; 和可以相同或不同的R 4，R 5和R 6各自表示氢原子或取代或未取代的烷基; 或者R 3和R 4可以一起形成5元环; 或者R 5和R 6可以一起形成环烷基; 条件是当R 3和R 4一起形成苯并呋喃或苯并[b]噻吩时，R6为零。

64. 发明授权

US06239077B1 Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof 有权
标题翻译：氨基乙腈衍生物农业和园艺杀虫剂含有相同的用途
公开(公告)号：US06239077B1
公开(公告)日：2001-05-29
申请号：US09295319
申请日：1999-04-21
申请人： Nobuharu Andoh , Osamu Sanpei , Kazuyuki Sakata
发明人： Nobuharu Andoh , Osamu Sanpei , Kazuyuki Sakata
IPC分类号： A01N3734
CPC分类号： C07D213/30 , A01N37/26 , A01N37/34 , C07C255/26 , C07C255/57 , C07C309/65 , C07C311/09 , C07C317/22 , C07C317/44 , C07C317/50 , C07C323/19 , C07C323/20 , C07C323/60 , C07C323/62 , C07C2601/02 , C07C2601/14 , C07D213/64 , C07D213/65 , C07D213/69 , C07D213/81 , C07D213/82 , C07D213/85
摘要： An aminoacetonitrile derivative of the formula (I): (wherein Ar1 and Ar2 represents phenyl group; substituted phenyl group having at least one subsituent selected from halogen atom, nitro group, cyano group, (halo) C1-C6 alkyl group, (halo) C1-C6 alkoxyl group, (substituted) pheny group, (substituted) phenyloxy group and (substituted) phenylacetylene group; (substituted) pyridyl group; and (substituted) naphthyl group, Q represents —C(R1)(R2)— (wherein R1 and R2 represent hydrogen atom, halogen atom, (halo) C1-C6 alkyl group, (halo) C1-C6 alkoxy group, (substituted) C3-C6 cycloalkyl group), or R1 and R2 may be bound to represent C2-C6 alkylene group), —CH═CH— or —C≡C—, d is 0 or an integer of 1, R3 represents hydrogen atom, (halo) C1-C6 alkyl group, R4, R5, R6, R7 and R8 represent hydrogen atom, halogen atom, (halo) C1-C6 alkyl group, W is —O—, —S—, —SO2— or —N(R9)— (wherein R9 is a hydrogen atom or C1-C6 alkyl group), and a and b are 0 or an integer of 1 to 4)), an agricultural and hortecultural insecticide containing as an active ingredient said derivative, and a method for using the insecticide.
摘要翻译：式（I）的氨基乙腈衍生物:(其中Ar1和Ar2表示苯基;具有至少一个选自卤素原子，硝基，氰基，（卤代）C 1 -C 6烷基，（卤素） C1-C6烷氧基，（取代）苯基，（取代）苯氧基和（取代）苯乙炔基;（取代）吡啶基;（取代）萘基，Q表示-C（R1）（R2） - （其中 R 1和R 2表示氢原子，卤素原子，（卤素）C 1 -C 6烷基，（卤素）C 1 -C 6烷氧基，（取代的）C 3 -C 6环烷基），或者R 1和R 2可以结合表示C 2 -C 6 亚烷基），-CH = CH-或-C = C-，d为0或整数1，R 3表示氢原子，（卤素）C 1 -C 6烷基，R 4，R 5，R 6，R 7和R 8表示氢原子，卤素原子，（卤素）C 1 -C 6烷基，W是-O - ， - S - ， - SO 2 - 或-N（R 9） - （其中R 9是氢原子或C 1 -C 6烷基） a和b为0或1〜4的整数）），农业和水平含有作为活性成分的所述衍生物的文化杀虫剂以及使用杀虫剂的方法。

65. 发明授权

US6114572A Substituted phenols and thiophenols useful as antioxidant agents 失效
标题翻译：用作抗氧化剂的取代的酚和苯酚
公开(公告)号：US6114572A
公开(公告)日：2000-09-05
申请号：US974112
申请日：1997-11-19
申请人： Roger A. Parker , Paul S. Wright , Steven J. Busch , Kim S. Chen , Mark T. Yates
发明人： Roger A. Parker , Paul S. Wright , Steven J. Busch , Kim S. Chen , Mark T. Yates
IPC分类号： C07C43/23 , C07C69/017 , C07C323/20 , C07C67/02 , A01N31/00 , C07C41/00 , C07C59/00
CPC分类号： C07C43/23 , C07C323/20 , C07C69/017
摘要： The present invention provides compounds of the formula ##STR1## wherein X is selected from the group consisting of ##STR2## Y is thio, oxy or a methylene group; Z is hydrogen or --C(O)--(CH.sub.2).sub.m --Q wherein Q is hydrogen or --COOH and m is an integer 1, 2, 3 or 4;R.sub.1 is C.sub.1 -C.sub.6 alkyl; andR.sub.2, R.sub.3 and R.sub.4 are each independently hydrogen or C.sub.1 -C.sub.6 alkyl;or a stereoisomer thereof; useful for the treatment of atherosclerosis and chronic inflammatory disorders; for inhibiting cytokine-induced expression of VCAM-1 and/or ICAM-1; for inhibiting the peroxidation of LDL lipid; for lowering plasma cholesterol; and as anti-oxidant chemical additives useful for preventing oxidative deterioration in organic materials.
摘要翻译：本发明提供下式的化合物其中X选自Y是硫代，氧基或亚甲基; Z是氢或-C（O） - （CH 2）m-Q其中Q是氢或-COOH，m是整数1,2,3或4; R1是C1-C6烷基; 并且R 2，R 3和R 4各自独立地为氢或C 1 -C 6烷基; 或其立体异构体; 可用于治疗动脉粥样硬化和慢性炎症性疾病; 用于抑制VCAM-1和/或ICAM-1的细胞因子诱导的表达; 用于抑制LDL脂质的过氧化; 用于降低血浆胆固醇; 以及用作防止有机材料氧化变质的抗氧化剂。

66. 发明授权

US6103753A Intimal thickening inhibitory agent 失效
标题翻译：内膜增厚抑制剂
公开(公告)号：US6103753A
公开(公告)日：2000-08-15
申请号：US68610
申请日：1998-05-06
申请人： Osamu Cynshi , Reiko Sekimori , Yoshiaki Kato
发明人： Osamu Cynshi , Reiko Sekimori , Yoshiaki Kato
IPC分类号： C07C43/23 , C07C317/22 , C07C323/20 , A01N43/12
CPC分类号： C07C323/20 , C07C317/22 , C07C43/23
摘要： An intimal thickening inhibitory agent comprising, as an active ingredient, a compound represented by formula (1): ##STR1## wherein X represents an oxygen atom or a group of formula (2): ##STR2## wherein n represents an integer of from 0 to 2, R.sub.1 represents a hydrogen atom or an acyl group; R.sub.2 represents a hydrogen atom, a lower alkyl group or a lower alkenyl group; R.sub.3 represents a lower alkyl group; and R.sub.4, R.sub.5, and R.sub.6, which may be the same or different, each represent a hydrogen atom or a substituted or unsubstituted alkyl group; or R.sub.3 and R.sub.4 may be taken together to form a 5-membered ring; or R.sub.5 and R.sub.6 may be taken together to form a cycloalkyl group; provided that R.sub.6 is nil when R.sub.3 and R.sub.4 are taken together to form benzofuran or benzo[b]thiophene.
摘要翻译： PCT No.PCT / JP96 / 03279 Sec。 371日期：1998年5月6日 102（e）日期1998年5月6日PCT 1996年11月8日PCT PCT。公开号WO97 / 17066 日期：1997年5月15日一种内膜增稠抑制剂，其包含作为活性成分的由式（1）表示的化合物：其中X表示氧原子或式（2）的基团：其中n表示0至2的整数 R1表示氢原子或酰基; R2表示氢原子，低级烷基或低级烯基; R3表示低级烷基; 和可以相同或不同的R 4，R 5和R 6各自表示氢原子或取代或未取代的烷基; 或者R 3和R 4可以一起形成5元环; 或者R 5和R 6可以一起形成环烷基; 条件是当R 3和R 4一起形成苯并呋喃或苯并[b]噻吩时，R6为零。

67. 发明授权

US5936128A 5,6-dihydropyrone derivatives as protease inhibitors and antiviral agents 失效
标题翻译：作为蛋白酶抑制剂的5,6-二氢吡喃酮衍生物和抗病毒剂
公开(公告)号：US5936128A
公开(公告)日：1999-08-10
申请号：US79689
申请日：1998-05-15
申请人： Edmund Lee Ellsworth , Elizabeth Lunney , Bradley Dean Tait
发明人： Edmund Lee Ellsworth , Elizabeth Lunney , Bradley Dean Tait
IPC分类号： C07D335/02 , A61K31/35 , A61K31/351 , A61K31/352 , A61K31/365 , A61K31/366 , A61K31/38 , A61K31/382 , A61K31/44 , A61K31/443 , A61P31/04 , A61P31/12 , A61P31/18 , C07C321/26 , C07C323/20 , C07C323/22 , C07C381/04 , C07D211/84 , C07D211/86 , C07D309/32 , C07D309/38 , C07D311/96 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/06 , C07D407/12 , C07D317/44
CPC分类号： C07D405/04 , C07C321/26 , C07C323/20 , C07C323/22 , C07D211/86 , C07D309/32 , C07D311/96 , C07D405/12 , C07D407/06 , C07D407/12 , C07C2101/08 , C07C2101/10 , C07C2101/14 , C07C2101/16
摘要： The present invention relates to novel 5,6-dihydropyrone derivatives and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The 5,6-dihydropyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized 5,6-dihydropyrones and of related structures.
摘要翻译：本发明涉及新颖的5,6-二氢吡喃酮衍生物和有效抑制HIV天冬氨酰蛋白酶阻断HIV感染性的相关结构。 5,6-二氢吡喃酮衍生物可用于开发用于治疗细菌和病毒感染和疾病（包括AIDS）的治疗。本发明还涉及多官能化的5,6-二氢吡喃的合成方法和相关结构。

68. 发明授权

US5698702A Intermediate compound for use in production of dihalopropene compound 失效
标题翻译：用于生产二卤丙烯化合物的中间体化合物
公开(公告)号：US5698702A
公开(公告)日：1997-12-16
申请号：US600179
申请日：1996-02-12
申请人： Noriyasu Sakamoto , Masaya Suzuki , Toshio Nagatomi , Kazunori Tsushima , Kimitoshi Umeda
发明人： Noriyasu Sakamoto , Masaya Suzuki , Toshio Nagatomi , Kazunori Tsushima , Kimitoshi Umeda
IPC分类号： C07C43/285 , A01N31/14 , A01N31/16 , A01N43/40 , A01P7/02 , A01P7/04 , C07C43/267 , C07C43/29 , C07C43/295 , C07C205/38 , C07C215/82 , C07C233/25 , C07C251/48 , C07C255/54 , C07C317/22 , C07C323/20 , C07D213/64 , C07D213/643 , C07D213/74 , C07D317/54 , C07D319/16 , C07C43/225 , C07C43/23
CPC分类号： C07D213/64 , A01N31/16 , A01N43/40 , C07C205/38 , C07C233/25 , C07C251/48 , C07C255/54 , C07C317/22 , C07C323/20 , C07C43/29 , C07D213/74 , C07D317/54 , C07D319/16
摘要： There is disclosed a dihalopropene compound of the formula I: ##STR1## wherein l is an integer of 1 to 5; m is an integer of 1 to 4; R.sup.1 's and R.sup.2 's are the same or different and are independently halogen or various other groups; D is oxygen; X's are the same or different and are independently chlorine or bromine; Y is oxygen; Z, P and Q are the same or different and are independently nitrogen or CH, provided that P and Q are not simultaneously nitrogen, and when Y is sulfur, Z is CH. Also disclosed is an insecticide/acaricide comprising the dihalopropene compound as an active ingredient. The dihalopropene compound exhibits excellent insecticidal/acaricidal action. Further disclosed is an intermediate compound for use in the production of the dihalopropene compound.
摘要翻译：公开了式I的二卤丙烯化合物：其中l为1至5的整数; m为1〜4的整数。 R1和R2相同或不同，独立为卤素或其他各种基团; D是氧; X是相同或不同的，独立地是氯或溴; Y是氧; Z，P和Q相同或不同，独立地为氮或CH，条件是P和Q不同时为氮，当Y为硫时，Z为CH。还公开了包含二卤丙烯化合物作为活性成分的杀虫剂/杀螨剂。二卤丙烯化合物显示出优异的杀虫/杀螨作用。还公开了用于制备二卤丙烯化合物的中间体化合物。

69. 发明授权

US5656619A Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom 失效
标题翻译：二苯基杂烷基衍生物，其制备方法和由其制备的药物和化妆品
公开(公告)号：US5656619A
公开(公告)日：1997-08-12
申请号：US466131
申请日：1995-06-06
申请人： Bernd Janssen , Hans-Heiner Wuest
发明人： Bernd Janssen , Hans-Heiner Wuest
IPC分类号： A61K8/33 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/67 , A61K31/195 , A61Q19/00 , C07C37/11 , C07C39/17 , C07C43/20 , C07C43/205 , C07C43/21 , C07C43/23 , C07C45/44 , C07C47/575 , C07C51/367 , C07C59/70 , C07C65/21 , C07C65/24 , C07C65/26 , C07C69/76 , C07C69/92 , C07C205/06 , C07C205/34 , C07C205/35 , C07C205/37 , C07C211/60 , C07C217/48 , C07C217/58 , C07C217/76 , C07C217/86 , C07C223/06 , C07C229/38 , C07C229/60 , C07C233/18 , C07C233/25 , C07C233/43 , C07C233/47 , C07C233/48 , C07C233/75 , C07C235/42 , C07C255/51 , C07C255/54 , C07C259/10 , C07C309/42 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/16 , C07C323/19 , C07C323/20 , C07C323/32 , C07C323/34 , C07C323/36 , C07C323/41 , C07C323/56 , C07C323/62 , C07C327/30 , C07D263/58 , C07D311/72 , C07F9/38 , C07F9/40 , C07C257/04
CPC分类号： A61K8/46 , A61K8/33 , A61K8/34 , A61K8/36 , A61K8/37 , A61K8/40 , A61K8/41 , A61K8/411 , A61K8/42 , A61K8/445 , A61K8/671 , A61Q19/00 , C07C205/06 , C07C205/34 , C07C205/35 , C07C205/37 , C07C211/60 , C07C217/48 , C07C217/58 , C07C217/76 , C07C217/86 , C07C223/06 , C07C229/38 , C07C229/60 , C07C233/18 , C07C233/25 , C07C233/43 , C07C233/47 , C07C233/48 , C07C233/75 , C07C235/42 , C07C255/54 , C07C259/10 , C07C309/42 , C07C317/22 , C07C317/32 , C07C317/44 , C07C323/16 , C07C323/19 , C07C323/20 , C07C323/32 , C07C323/34 , C07C323/36 , C07C323/41 , C07C323/56 , C07C323/62 , C07C327/30 , C07C37/18 , C07C39/17 , C07C41/26 , C07C43/202 , C07C43/2055 , C07C43/21 , C07C43/23 , C07C45/44 , C07C47/575 , C07C51/367 , C07C65/24 , C07C65/26 , C07C69/76 , C07C69/92 , C07D263/58 , C07D311/58 , C07D311/70 , C07D311/72 , C07D317/22 , C07F9/3834 , C07F9/4021 , C07C2102/10
摘要： Abstract of the Disclosure: Diphenylheteroalkyl derivatives of the formula I ##STR1## where A and R.sup.1 -R.sup.6 have the meanings specified in the description, and the preparation thereof are described.The substances are suitable for controlling diseases and as cosmetic agents.
摘要翻译：本发明摘要：描述了其中A和R 1 -R 6具有本说明书中规定的含义的式I的（I）的二苯基杂烷基衍生物及其制备。该物质适用于控制疾病和化妆品。

70. 发明授权

US5627205A Substituted phenoxyisobutyric acids and esters 失效
标题翻译：取代的苯氧基异丁酸和酯
公开(公告)号：US5627205A
公开(公告)日：1997-05-06
申请号：US510857
申请日：1995-08-03
申请人： Gilbert Regnier , Claude Guillonneau , Jean-Paul Vilaine , Albert Lenaers , Christine Breugnot
发明人： Gilbert Regnier , Claude Guillonneau , Jean-Paul Vilaine , Albert Lenaers , Christine Breugnot
IPC分类号： C07C51/367 , A61K31/19 , A61K31/215 , A61K31/35 , A61K31/352 , A61P3/06 , A61P3/08 , A61P3/10 , A61P9/10 , C07C51/09 , C07C59/68 , C07C59/90 , C07C67/343 , C07C69/712 , C07C69/734 , C07C319/14 , C07C319/20 , C07C323/20 , C07C323/22 , C07D311/72 , A61K31/34 , C07D307/80
CPC分类号： C07C323/22 , C07C323/20 , C07C59/68 , C07C69/712 , C07D311/72 , Y02P20/55
摘要： New substituted phenoxyisobutyric acids and esters that can be used as medicaments and correspond to the formula: ##STR1## wherein X, A, R, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and Z are as defined in the description.Those compounds and their physiologically tolerable salts can be used therapeutically.
摘要翻译：新的取代的苯氧基异丁酸和酯可以用作药物并对应于下式：其中X，A，R，R 1，R 2，R 3，R 4，R 5，R 6，R 7和Z如说明书中所定义。那些化合物及其生理上可耐受的盐可用于治疗。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式