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61. 发明授权

US5322574A Method of manufacturing a high strength, high conductivity copper-silver alloy 失效
标题翻译：制造高强度，高电导率铜 - 银合金的方法
公开(公告)号：US5322574A
公开(公告)日：1994-06-21
申请号：US743223
申请日：1991-08-09
申请人： Yoshikazu Sakai , Kiyoshi Inoue , Hiroshi Maeda
发明人： Yoshikazu Sakai , Kiyoshi Inoue , Hiroshi Maeda
IPC分类号： C22C9/00 , C22F1/00 , C22F1/02 , C22F1/08 , H01L23/48 , H01L23/495
CPC分类号： H01L23/49579 , C22F1/02 , C22F1/08 , H01L2924/0002
摘要： The present invention provides a new copper alloy containing silver from 4 to 32 at. %, which is useful for a magnet conductor, an IC lead frame, etc., having simultaneously a high strength and a high conductivity, manufactured by blending from 4 to 32 at. % silver into copper, casting, rapidly cooling and cold-working wherein the cold-working step includes a hot working treatment at a reduction rate of 40% to 70% at temperatures of from 300.degree. to 500.degree. C.
摘要翻译：本发明提供一种含有4〜32at银的新型铜合金。％，其对于具有高强度和高导电性的磁体导体，IC引线框架等是有用的，通过混合4至32at制造。％银成铜，铸造，快速冷却和冷加工，其中冷加工步骤包括在300℃至500℃的温度下以40％至70％的还原率进行的热加工处理。

62. 发明授权

US5299411A Wrapping sheet winding apparatus 失效
标题翻译：包装纸卷绕装置
公开(公告)号：US5299411A
公开(公告)日：1994-04-05
申请号：US982035
申请日：1992-11-24
申请人： Kiyohumi Yamamoto , Hiroshi Maeda , Susumu Suzuki
发明人： Kiyohumi Yamamoto , Hiroshi Maeda , Susumu Suzuki
IPC分类号： B65B11/04 , B65B25/14
CPC分类号： B65B25/148
摘要： A wrapping sheet is disposed on a roll so that marginal portions of the wrapping sheet extend beyond the respective side faces of the roll. A wrapping sheet winding apparatus for winding the wrapping sheet around the roll has a pair of chucks which are drivingly engaged with a core of the roll and rotate the roll to wind therearound the wrapping sheet. Each of the chucks is provided with suction holes formed on the outer peripheral surface thereof.
摘要翻译：包装片设置在卷筒上，使得包装片的边缘部分延伸超出卷的相应侧面。用于将包裹片卷绕在卷上的包装纸卷绕装置具有一对卡盘，该卡盘与卷轴的芯部驱动地接合，并使卷筒旋转以围绕包装片卷绕。每个卡盘设置有形成在其外周面上的吸孔。

63. 发明授权

US5298524A Acidic polycyclic ether antibiotic having an anticoccidial and growth promotant activity 失效
标题翻译：具有抗球虫和生长促进活性的酸性多环醚抗生素
公开(公告)号：US5298524A
公开(公告)日：1994-03-29
申请号：US655440
申请日：1992-03-27
申请人： John P. Dirlam , Walter P. Cullen , Hiroshi Maeda , Junsuke Tone
发明人： John P. Dirlam , Walter P. Cullen , Hiroshi Maeda , Junsuke Tone
IPC分类号： A23K1/17 , A23K1/18 , C07H19/01 , C12P17/18 , C12P19/44 , A01N43/12
CPC分类号： C07H19/01 , A23K20/195 , A23K50/30 , C12P17/18 , C12P19/44 , Y10S435/825
摘要： An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53764. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.
摘要翻译： PCT No.PCT / US88 / 01954 Sec。 371日期：1992年3月27日 102（e）1992年3月27日PCT PCT。1988年6月9日。具有通过X射线晶体学建立的结构的酸性多环醚抗生素通过新型微生物Actinomadura sp。 ATCC 53764.这种新型抗生素可用作鸡的抗球虫病，预防或治疗猪痢疾，以及作为牛和猪的生长促进剂。

64. 发明授权

US5180582A Superoxide dismutase derivatives, a method of producing the same and medicinal uses of the same 失效
标题翻译：超氧化物歧化酶衍生物，其制备方法及其药用用途
公开(公告)号：US5180582A
公开(公告)日：1993-01-19
申请号：US836861
申请日：1992-02-19
申请人： Hiroshi Maeda , Fujio Suzuki , Tatsuya Oda
发明人： Hiroshi Maeda , Fujio Suzuki , Tatsuya Oda
IPC分类号： A61K38/44 , C12N9/02
CPC分类号： C12N9/0089 , A61K38/446
摘要： The invention provides a superoxide dismutase derivative of the general formula[SOD][Z]wherein [SOD] represents a superoxide dismutase having 1 to 22 or 24 groups each derived from an amino groups by removal of one hydrogen atom in lieu of amino groups; [Z] represents a monovalent copolymer group, constituting units of which are a group of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each represents a hydrogen atom or a residue derived by a removal of a hydroxyl group from an alkanol of 1 to 8 carbon atoms, an ethylene glycol monoalkyl ether containing an alkyl moiety of 1 to 4 carbon atoms or a glycerin dialkyl ether containing alkyl moieties of 1 to 4 carbon atoms, provided that either R.sup.1 or R.sup.2 and either R.sup.3 or R.sup.4 each represents a hydrogen atom, and a residue derived from the group of the above-mentioned formula by removal of OR.sup.1, OR.sup.2, OR.sup.3 or OR.sup.4 group from one of its COOR.sup.1, COOR.sup.2, COOR.sup.3 and COOR.sup.4 groups (where the bond on the carbon atom of the carbonyl group is attached to [SOD]), said monovalent copolymer group having an average molecular weight of 500 to 200,000; and n represents an integer of 1 to 22 or 24 corresponding to the number of said groups each derived from an amino group by removal of one hydrogen atom in said [SOD], or a pharmaceutically acceptable salt thereof. There also is provided a method for producing the above derivative and salt. The invention is further directed to medicinal uses and pharmaceutical compositions for oral administration.
摘要翻译：本发明提供了一种通式[SOD] [Z]的超氧化物歧化酶衍生物，其中[SOD]代表通过除去一个氢原子代替氨基，每个衍生自氨基的具有1至22个或24个基团的超氧化物歧化酶; [Z]表示单价共聚物基团，其构成单元为式“IMAGE”的基团，其中R 1，R 2，R 3和R 4各自表示氢原子或通过从烷醇中除去羟基而得到的残基 1至8个碳原子的烷基部分，含有1至4个碳原子的烷基部分的乙二醇单烷基醚或含有1至4个碳原子的烷基部分的甘油二烷基醚，条件是R 1或R 2以及R 3或R 4各自表示氢原子和衍生自上述式的基团的残基，通过从其COOR1，COOR2，COOR3和COOR4基团之一除去OR1，OR2，OR3或OR4基团（其中羰基的碳原子上的键所述单价共聚物基团的平均分子量为500〜200,000; n表示通过除去所述[SOD]中的一个氢原子而衍生自氨基的所述基团的数目的1-22或24的整数或其药学上可接受的盐。还提供了制备上述衍生物和盐的方法。本发明进一步涉及药物用途和用于口服给药的药物组合物。

65. 发明授权

US5147858A Acidic polycyclic ether useful as an anticoccidial agent and as a growth promotant 失效
标题翻译：酸性聚合物有效地作为抗焦虑剂和作为生长促进剂
公开(公告)号：US5147858A
公开(公告)日：1992-09-15
申请号：US487947
申请日：1990-04-16
申请人： John P. Dirlam , Walter P. Cullen , Hiroshi Maeda , Junsuke Tone
发明人： John P. Dirlam , Walter P. Cullen , Hiroshi Maeda , Junsuke Tone
IPC分类号： C12P19/00 , A23K1/16 , A23K1/17 , A61K31/35 , A61K31/70 , A61K31/7028 , A61K31/7042 , A61K31/7048 , A61P31/00 , A61P33/02 , C07D493/10 , C07H7/06 , C07H15/04 , C07H17/04 , C07H19/01 , C12N1/20 , C12P17/06 , C12P19/60 , C12R1/03
CPC分类号： C07H19/01 , A23K20/195 , Y10S435/825
摘要： An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Actinomadura sp. ATCC 53676. This novel antibiotic is useful as an anticoccidial in chickens and as a growth promotant in cattle and swine.

66. 发明授权

US5073567A Antiparasitic agent 失效
标题翻译：抗菌剂
公开(公告)号：US5073567A
公开(公告)日：1991-12-17
申请号：US557885
申请日：1990-07-25
申请人： Yasuhiro Kojima , Hiroshi Maeda , Satoshi Nishiyama , David A. Perry
发明人： Yasuhiro Kojima , Hiroshi Maeda , Satoshi Nishiyama , David A. Perry
IPC分类号： C12P17/18 , A01N43/90 , A23K20/195 , A61K31/365 , A61P3/00 , A61P33/00 , A61P33/10 , C07D493/22 , C12N1/20 , C12P17/08 , C12R1/465
CPC分类号： C07D493/22 , A01N43/90 , A23K20/195
摘要： An antibiotic compound of the formula: ##STR1## is an antiparasitic agent active against insect pests, acari, free living nematodes and endo- and ectoparasites. It is prepared by fermentation using the microorganism Streptomyces griseochromogenes ATCC 53928.

67. 发明授权

US5064855A Acid polycyclic ether antibiotic 失效
标题翻译：酸性多环醚抗生素
公开(公告)号：US5064855A
公开(公告)日：1991-11-12
申请号：US649120
申请日：1991-01-28
申请人： Walter P. Cullen , James R. Hauske , Gloria J. Kostek , Hiroshi Maeda , Junsuke Tone
发明人： Walter P. Cullen , James R. Hauske , Gloria J. Kostek , Hiroshi Maeda , Junsuke Tone
IPC分类号： C07D493/10 , C12P17/06
CPC分类号： C07D493/10 , C12P17/06 , C12R1/465
摘要： An acidic polycyclic ether antibiotic, having structure established by X-ray crystallography, is formed by fermentation of a novel microorganism, Streptomyces sp. ATCC 53862. This novel antibiotic is useful as an anticoccidial in chickens, in the prevention or treatment of swine dysentery, and as a growth promotant in cattle and swine.
摘要翻译：通过X射线晶体学建立的结构的酸性多环醚类抗生素是通过新型微生物Streptomyces sp。 ATCC 53862.这种新型抗生素可用作鸡的抗球虫，预防或治疗猪痢疾，以及作为牛和猪的生长促进剂。

68. 发明授权

US5061741A Method for preparing an oil-in-water type uniform dispersion of liquid droplets and polymerization method for preparing polymer beads of uniform particle size 失效
标题翻译：用于制备液体水溶液的水性均匀分散体的方法和用于制备均匀颗粒尺寸的聚合物珠粒的聚合方法
公开(公告)号：US5061741A
公开(公告)日：1991-10-29
申请号：US611507
申请日：1990-11-13
申请人： Eiji Miyata , Kiyoto Ando , Hiroshi Maeda , Hiroshi Arataki , Seiji Sudo
发明人： Eiji Miyata , Kiyoto Ando , Hiroshi Maeda , Hiroshi Arataki , Seiji Sudo
IPC分类号： B01J19/26 , C08F2/00 , C08F2/04 , C08F2/16
CPC分类号： C08F2/16 , B01J19/26 , B01J2219/00164 , Y10S526/918
摘要： A method for preparing an oil-in-water type uniform dispersion of liquid droplets, which comprises ejecting into an aqueous medium containing a dispersion stabilizer, which forms a continuous phase and moves upwards, a hydrophobic liquid having a specific gravity smaller than the aqueous medium, through a nozzle plate having a plurality of perforations capable of ejecting the hydrophobic liquid upwards, to form liquid droplets of the hydrophobic liquid in the aqueous medium, wherein a nozzle plate having a number of perforations for ejection arranged in a ring form is used as said nozzle plate, and a polymerization method for preparing polymer beads of uniform particle size, which comprises applying the method for preparing an oil-in-water type uniform dispersion of liquid droplets.

69. 发明授权

US5041935A Rotary actuator for positioning magnetic heads in a disk drive 失效
标题翻译：用于将磁头定位在磁盘驱动器中的旋转执行器
公开(公告)号：US5041935A
公开(公告)日：1991-08-20
申请号：US392499
申请日：1989-08-11
申请人： Keiji Aruga , Norihiko Suzuki , Tomoyoshi Yamada , Hiroshi Maeda , Takahiro Imamura
发明人： Keiji Aruga , Norihiko Suzuki , Tomoyoshi Yamada , Hiroshi Maeda , Takahiro Imamura
IPC分类号： G11B5/55 , H01F7/14
CPC分类号： G11B5/5521 , H01F7/145
摘要： A rotary actuator for positioning magnetic heads in a disk drive, comprising a stator assembly and a rotor assembly. An arm assembly having magnetic heads are fixed to the rotor assembly, which rotates back and forth within a limited angle range around a fixed axis of the rotary actuator due to the forces between plural magnets and driving current which flows though flat coils. Two flat coils are aranged on an arcuate inner surface of the stator such that two adjacent vertical parallel portions thereof closely contact with each other. Two flat coils have an electrical connection with a driving source that the currents through the two adjacently parallel portions flow in the same direction. Three permanent magnets are disposed on the rotor surface, the central magnet having a greater lateral width than that of other two side magnets, and a polarity of the central magnet is opposite to that of other magnets. In another embodiment, each of flat coils comprises an inner coil and an outer coil resulting in enhancing the torque of the rotary actuator. Several modifications of coil and permanent magnet arrangement, and other related improvements in the structure thereof are also disclosed.

70. 发明授权

US5026772A Lyophilized pharmaceutical composition of neocarzinostatin derivative 失效
标题翻译：冻干药物组合物新辅佐星素衍生物
公开(公告)号：US5026772A
公开(公告)日：1991-06-25
申请号：US237950
申请日：1988-08-29
申请人： Mitsugu Kobayashi , Go Ohtani , Jun Sekino , Toshimitsu Konno , Hiroshi Maeda
发明人： Mitsugu Kobayashi , Go Ohtani , Jun Sekino , Toshimitsu Konno , Hiroshi Maeda
IPC分类号： A61K9/19 , A61K47/48
CPC分类号： A61K47/48176 , A61K9/19
摘要： A lyophilized pharmaceutical composition comprised of a neocarzinostatin derivative having the formula (SMA)-(NCS)-(SMA), is made by a method including dissolving the neocarzinostatin derivative and stabilizing agent comprising at least one saccharide selected from the group consisting of monosaccharides, disaccharides and dextran in an aqueous buffer solution having a pH ranging from about 7.5 to about 9.5, the stabilizing agent being present in an amount by weight (titer) which is at least equal to that of the neocarzinostatin derivative, to provide a solution; adjusting the pH of the solution to provide a pH-adjusted solution having a pH of about 8.0.+-.0.5; sterilizing the pH-adjusted solution by filtration to provide a sterilized solution; and lyophilizing the sterilized solution.

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