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61. 发明申请

US20100145174A1 System And Method For Providing A Personalized Tool For Estimating Glycated Hemoglobin 审中-公开
标题翻译：提供用于估计糖化血红蛋白的个性化工具的系统和方法
公开(公告)号：US20100145174A1
公开(公告)日：2010-06-10
申请号：US12372662
申请日：2009-02-17
申请人： Clifton A. Alferness , Gust H. Bardy
发明人： Clifton A. Alferness , Gust H. Bardy
IPC分类号： A61B5/00
CPC分类号： G06F19/3475 , A61B5/14532 , G01N33/723 , G06F19/3456 , G06F19/3481 , G16H10/60 , G16H15/00 , G16H50/50
摘要： A system and method for providing a personalized tool for estimating glycated hemoglobin is provided. An electronically-stored history of empirically measured glucose levels for a patient is maintained over a set period of time in order of increasing age. A decay factor is applied to each of the measured glucose levels. The measured glucose levels are aggregated and scaled as decayed into an estimate of glycated hemoglobin for the time period. The glycated hemoglobin estimate is displayed to the patient.
摘要翻译：提供了一种用于提供用于估计糖化血红蛋白的个性化工具的系统和方法。电子存储病历经验测量的葡萄糖水平的历史在一定时间段内按照年龄的增加来维持。对每个测量的葡萄糖水平应用衰减因子。测量的葡萄糖水平被聚合并按比例衰变为糖化血红蛋白的估计时间段。糖尿病血红蛋白估计显示给患者。

62. 发明申请

US20080172074A1 Transesophageal gastric reduction method and device for practicing same 审中-公开
标题翻译：经食道胃缩小方法及其实践手段
公开(公告)号：US20080172074A1
公开(公告)日：2008-07-17
申请号：US11654397
申请日：2007-01-16
申请人： Steve G. Baker , Sean Totten , John C. Bayne , Clifton A. Alferness , Stefan J. M. Kraemer
发明人： Steve G. Baker , Sean Totten , John C. Bayne , Clifton A. Alferness , Stefan J. M. Kraemer
IPC分类号： A61B17/30
CPC分类号： A61B17/068 , A61B17/0401 , A61B2017/0409 , A61B2017/0419 , A61F5/0086
摘要： A system and method forms a gastric reduction pouch within a stomach associated with an esophagus. The method includes the steps of delivering, down the esophagus, a substantially planar annular member into the stomach, drawing stomach wall tissue to a juxtaposed relation with the annular member; and securing, to the annular member, the stomach wall tissue juxtaposed to the annular member.
摘要翻译：系统和方法在与食道相关的胃内形成胃减压袋。该方法包括以下步骤：将食道向下传送基本上平面的环形构件进入胃部，将胃壁组织拉伸成与环形构件并置的关系; 并且将与所述环形构件并置的胃壁组织固定到所述环形构件。

63. 发明申请

US20080119866A1 Removable anchored lung volume reduction devices and methods 有权
标题翻译：可拆卸锚固肺体积减少装置及方法
公开(公告)号：US20080119866A1
公开(公告)日：2008-05-22
申请号：US11880090
申请日：2007-07-19
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61M29/00
CPC分类号： A61B17/12104 , A61B17/12022 , A61B17/1204 , A61B17/12159 , A61B17/12172 , A61B2017/1205 , A61B2017/22051 , A61B2017/22067 , A61F2002/043
摘要： An intra-bronchial device may be placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes an obstructing member that prevents air from being inhaled into the lung portion, and an anchor that anchors the obstruction device within the air passageway. The anchor may piercingly engage the air passageway wall. The anchor may be releasable from the air passageway for removal of the obstructing member. The anchor may be releasable by collapsing a portion of the obstructing member, or by drawing the obstructing member toward the larynx. The obstructing member may be a one-way valve.
摘要翻译：可以将支气管内装置放置并锚定在患者的空气通道中以折叠与空气通道相关联的肺部分。该装置包括防止空气被吸入肺部的阻塞构件，以及将阻塞装置固定在空气通道内的锚固件。锚固件可以穿透空气通道壁。锚固件可以从空气通道释放以去除阻塞构件。锚固件可以通过塌缩阻塞构件的一部分，或者通过将阻塞构件拉向喉部来释放。阻塞构件可以是单向阀。

64. 发明授权

US07255674B2 Cardiac reinforcement device 失效
公开(公告)号：US07255674B2
公开(公告)日：2007-08-14
申请号：US10672227
申请日：2003-09-26
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61F2/00
CPC分类号： A61F2/2481 , A61F2002/2484 , A61F2250/0003 , A61M1/1008 , A61M1/106 , A61M1/1068 , A61M1/12
摘要： The present disclosure is directed to a cardiac reinforcement device (CRD) and method for the treatment of cardiomyopathy. The CRD provides for reinforcement of the walls of the heart by constraining cardiac expansion, beyond a predetermined limit, during diastolic expansion of the heart. A CRD of the invention can be applied to the epicardium of the heart to locally constrain expansion of the cardiac wall or to circumferentially constrain the cardiac wall during cardiac expansion.

65. 发明授权

US06997865B2 Cardiac support device with anti-fibrosis lining 有权
标题翻译：心脏支持装置具有抗纤维化内衬
公开(公告)号：US06997865B2
公开(公告)日：2006-02-14
申请号：US10794311
申请日：2004-03-05
申请人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
发明人： Clifton A. Alferness , Jai Shankar Raman , John Melmouth Power
IPC分类号： A61F13/00
CPC分类号： A61F2/2481 , A61F2002/0068
摘要： A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译：生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积，以将其插入体积中并使护套滑过心脏。护套具有在上下端之间的纵向尺寸，足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端。护套适于固定在心脏上，护套至少围绕瓣膜环和心室下肢。护套在心脏上是可调节的，以贴合地符合心脏的外部几何形状，并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张，并允许心脏收缩期间不受阻碍的收缩。

66. 发明授权

US06902524B2 Cardiac disease treatment and device 有权
公开(公告)号：US06902524B2
公开(公告)日：2005-06-07
申请号：US10716020
申请日：2003-11-17
申请人： Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
发明人： Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
IPC分类号： A61B17/00 , A61F2/00 , A61F2/24 , A61F9/00 , A61F11/00 , A61F13/00 , A61M1/10
CPC分类号： A61F2/2481 , Y10S623/904
摘要： A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.

67. 发明授权

US5549641A Atrial fibrillation type selective cardiovertor and method 失效
标题翻译：心房颤动型选择性心脏转移器及方法
公开(公告)号：US5549641A
公开(公告)日：1996-08-27
申请号：US331898
申请日：1994-10-31
申请人： Gregory M. Ayers , Clifton A. Alferness
发明人： Gregory M. Ayers , Clifton A. Alferness
IPC分类号： A61N1/362 , A61N1/39
CPC分类号： A61N1/3918 , A61N1/3622 , A61N1/3962 , A61N1/395
摘要： An atrial cardiovertor/defibrillator provides therapy to the atria corresponding to the type of atrial arrhythmia occurring in the atria of the heart. The atrial cardiovertor/defibrillator includes a memory for storing respective different criteria for each of different types of atrial arrhythmia, a sensor for sensing activity of at least one of the atria of the heart to provide an electrogram signal, and a cardiovertor for providing a corresponding therapy to the heart for each of the different types of atrial arrhythmia. The cardiovertor/defibrillator further includes an atrial arrhythmia detector responsive to the electrogram signal and the stored criteria for identifying one of the types of atrial arrhythmia to cause the cardiovertor to provide therapy to the heart corresponding to the identified atrial arrhythmia.
摘要翻译：房性心律转复/除纤颤器对心房心房发生心房心律失常类型的心房提供治疗。心房心律转移除颤器包括存储器，用于存储针对不同类型心房心律失常的各种不同的标准，用于感测心脏心房中的至少一个的活动以提供电描记图信号的传感器，以及用于提供对应的心律转换器治疗心脏每种不同类型的心房心律失常。心律转移除颤器进一步包括心律失常检测器，其响应于电描记图信号和存储的标准，用于识别心房心律失常的类型之一，以使心脏转移器向心脏对应于所确定的房性心律失常提供治疗。

68. 发明授权

US5486198A Atrial defibrillator and method for providing interval timing of successive intervals prior to cardioversion 失效
标题翻译：心房除颤器和在心脏复律之前提供连续间隔的间隔时间的方法
公开(公告)号：US5486198A
公开(公告)日：1996-01-23
申请号：US289701
申请日：1994-08-12
申请人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
发明人： Gregory M. Ayers , Clifton A. Alferness , Harley G. White
IPC分类号： A61N1/39
CPC分类号： A61N1/3956 , A61N1/3918 , A61N1/395 , A61N1/3987
摘要： An atrial defibrillator and method provides cardioverting electrical energy to the atria of a human heart after timing successive R to R intervals. A detector detects ventricular activations of the heart and a timer times intervals between immediately successive ventricular activations. A cardiovertor applies cardioverting electrical energy to the atria of the heart when a second time interval between a third ventricular activation and a second ventricular activation immediately preceding the third ventricular activation satisfies a predetermined criteria with respect to a first time interval between the second ventricular activation and a first ventricular activation immediately preceding the second ventricular activation.
摘要翻译：心房除颤器和方法在定时连续的R至R间隔之后向心脏心房提供心律转复的电能。检测器检测心脏的心室激活，并且定时器在紧接着的心室激活之间进行时间间隔。当在第三心室激活之前的第三心室激活和第二心室激活之间的第二时间间隔相对于第二心室激活和第二心室激活之间的第一时间间隔满足预定标准时，心律转换器将心脏转换电能施加到心脏心房在第二次心室激活之前的第一次心室激活。

69. 发明授权

US5330496A Vascular catheter assembly for tissue penetration and for cardiac stimulation and methods thereof 失效
标题翻译：用于组织穿透和用于心脏刺激的血管导管组件及其方法
公开(公告)号：US5330496A
公开(公告)日：1994-07-19
申请号：US695724
申请日：1991-05-06
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61B17/00 , A61B17/32 , A61M25/01 , A61N1/05
CPC分类号： A61B5/0422 , A61B17/320016 , A61M25/0105 , A61N1/0587 , A61B2017/00247 , A61B2018/00392 , A61M25/0113
摘要： A vascular catheter apparatus for penetration through tissue and for cardiac stimulation, and a methods thereof, are disclosed. The apparatus includes a tubular member having a lumen, and a blunt-end stylet within the lumen. An actuation mechanism causes axial movement of the stylet relative to the catheter tube such that the blunt end of the stylet separate tissue for passage of the catheter through the bored tissue. The stylet itself, or an additional stylet, includes a proximal electrode adapted to be oriented in a cardiac chamber and a distal electrode adapted to be oriented adjacent to the epicardium of the heart to cause cardiac stimulation.
摘要翻译：公开了用于穿透组织并用于心脏刺激的血管导管装置及其方法。该装置包括具有内腔的管状构件和内腔内的平头端管心针。致动机构导致探针相对于导管的轴向移动，使得探针的钝端分开组织以使导管通过钻孔组织。探针本身或另外的探针包括适于被定向在心室中的近端电极和适于被定向成邻近心脏心外膜的远端电极以引起心脏刺激。

70. 发明授权

US5304218A Cardiac lead implanting arrangement and method 失效
标题翻译：心脏铅植入装置及方法
公开(公告)号：US5304218A
公开(公告)日：1994-04-19
申请号：US892177
申请日：1992-06-02
申请人： Clifton A. Alferness
发明人： Clifton A. Alferness
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An arrangement and method facilitates the implantation of an electrode of an endocardial or intravenous lead at an implantation site within the heart of a human. The arrangement includes a guide wire which is formed of flexible material and which may be fed along a predetermined path which includes the implantation site. The arrangement further includes a lead formed of flexible material which includes a proximal end, a distal end, and an electrode to be implanted. The lead further includes an integrally formed follower which slidingly engages the guide wire to permit the lead to be guided along the predetermined path until the electrode to be implanted resides at its implantation site. Thereafter, the guide wire is retracted along the predetermined path to cause the electrode to remain at its implantation site.
摘要翻译：布置和方法有助于在人的心脏内的植入部位植入心内膜或静脉内引线的电极。该装置包括由柔性材料形成并且可以沿着包括植入部位的预定路径进给的导丝。该装置还包括由柔性材料形成的引线，其包括近端，远端和待植入的电极。引线还包括一体形成的从动件，其滑动地接合导丝，以允许引线沿着预定路径被引导，直到待植入的电极位于其注入位置。此后，引导线沿着预定路径缩回以使电极保持在其植入位置。

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