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61. 发明申请

US20060165728A1 Campylobacter glycans and glycopeptides 有权
标题翻译：弯曲杆菌聚糖和糖肽
公开(公告)号：US20060165728A1
公开(公告)日：2006-07-27
申请号：US10523459
申请日：2003-07-30
申请人： Noel Young , Jean-Robert Brisson , John Kelly , David Watson , Christine Szymanski , Harold Jarrell
发明人： Noel Young , Jean-Robert Brisson , John Kelly , David Watson , Christine Szymanski , Harold Jarrell
IPC分类号： A61K39/02 , C08B37/00 , C07K14/205 , C12Q1/04
CPC分类号： G01N33/56922 , A61K39/105 , C07H3/06 , G01N2400/02 , Y02A50/47
摘要： Multiple strains and species of Campylobacter were found to share a common glycan moitie which is present in a plurality of surface-exposed glycoproteins. This glycan has the formula: GalNAc-a1,4-GalNAc-a1,4-[Glc-β1,3]GalNAc-a1,4-GalNAc-a1,4-GalNAc-a1,3-Bac, wherein Bac is 2,4-diacetamido-2,4,6-trideoxy-D-glucopyranose. This glycan and immunologically active fragments of it have use as vaccines against campylobacter infection in humans and animals. As well, antibodies which specifically bind these compounds may be provided. Such antibodies and vaccines may be used to prevent or neutralize campylobacter infections in livestock thereby preventing this pathogen from entering the human food chain. The glycan may be linked to one or more amino acids to form a glycopeptide. As well, a method for determining the glycan structure of an intact glycoprotein consists of subjecting a sample to high resolution magic angle spinning nuclear magnetic resonance (HR-MAS-NMR) spectroscopy.
摘要翻译：发现多种菌株和种类的弯曲杆菌分享一种常见的多糖表面暴露糖蛋白中存在的多糖异味。该聚糖具有下式：GalNAc-a1,4-GalNAc-a1,4 [Glc-β1,3] GalNAc-a1,4-GalNAc-a1,4-GalNAc-a1,3-Bac，其中Bac为2， 4-二乙酰氨基-2,4,6-三脱氧-D-吡喃葡萄糖。该聚糖及其免疫活性片段可用作针对人和动物中弯曲杆菌感染的疫苗。同样，可以提供特异性结合这些化合物的抗体。这样的抗体和疫苗可用于预防或中和家畜中的弯曲杆菌感染，从而防止该病原体进入人类食物链。聚糖可以连接到一个或多个氨基酸以形成糖肽。同样，确定完整糖蛋白的聚糖结构的方法包括使样品进行高分辨率魔角旋转核磁共振（HR-MAS-NMR）光谱。

62. 发明授权

US06636468B2 Method and apparatus for laser power control during recording 有权
公开(公告)号：US06636468B2
公开(公告)日：2003-10-21
申请号：US09818055
申请日：2001-03-26
申请人： Dan Salmonsen , John Kelly
发明人： Dan Salmonsen , John Kelly
IPC分类号： G11B509
CPC分类号： G11B7/1267 , G11B7/00458
摘要： A method comprises writing data to a disk using a write laser, and halting recording at a stopping point, prior to an end of the disk. The method further comprises reading the data recorded on the disk and evaluating the data. The method further comprises adjusting the characteristics of the write laser, if appropriate, and restarting the writing using the adjusted characteristics for the write laser.

63. 外观设计

USD290040S Orthodontic bracket 失效
公开(公告)号：USD290040S
公开(公告)日：1987-05-26
申请号：US609068
申请日：1984-05-10
申请人： John Kelly
设计人： John Kelly

64. 发明授权

US4040629A Commodities board game apparatus 失效
标题翻译：商品棋盘游戏机
公开(公告)号：US4040629A
公开(公告)日：1977-08-09
申请号：US589019
申请日：1975-06-23
申请人： John Kelly
发明人： John Kelly
IPC分类号： A63F1/04 , A63F3/00 , A63F9/00 , A63F9/04 , A63F11/00
CPC分类号： A63F3/00063 , A63F1/04 , A63F2003/00066 , A63F2011/0018 , A63F2011/0067 , A63F2250/1073 , A63F9/0468
摘要： A game apparatus adapted to acquaint players with the procedures and risks in trading in the commodities market. The apparatus includes a game board that delineates a plurality of commodities and the conditions under which they are traded, a spinner on the deck board for establishing the beginning prices of each of the commodities, a deck of price fluctuation cards for randomly establishing daily changes in the price of each commodity, dial indicators associated with the board for showing the current price of each commodity as it fluctuates, and transaction slips for recording each player's trading transactions.
摘要翻译：一种游戏设备，适合于让玩家了解商品市场交易中的程序和风险。该装置包括描绘多个商品的游戏板及其交易条件，甲板上的旋转器，用于确定每个商品的起始价格，一组价格波动卡，用于随机地建立日常变化每个商品的价格，与董事会相关的指标指标，以显示每种商品的波动的当前价格，以及记录每个玩家的交易交易的交易单。

65. 发明授权

US09439708B2 Neuromodulation cryotherapeutic devices and associated systems and methods 有权
公开(公告)号：US09439708B2
公开(公告)日：2016-09-13
申请号：US13279326
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins , Michael Turovskiy
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2017/22054 , A61B2017/22067 , A61B2018/00023 , A61B2018/00166 , A61B2018/0022 , A61B2018/00232 , A61B2018/0025 , A61B2018/00261 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/0212 , A61B2018/0262
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.

66. 发明授权

US09238747B2 Stain blocking compositions 有权
标题翻译：污渍组合物
公开(公告)号：US09238747B2
公开(公告)日：2016-01-19
申请号：US12272016
申请日：2008-11-17
申请人： Jacob Wildeson , John Kelly , Audrey Cosyns , Harm Wiese
发明人： Jacob Wildeson , John Kelly , Audrey Cosyns , Harm Wiese
IPC分类号： C08L37/00 , C08L39/00 , B05D3/02 , C08L31/00 , C08L33/00 , C08F220/06 , C08L33/06 , C09D133/08 , C09D133/00 , C09D133/10 , C09D143/02
CPC分类号： C09D5/002 , C09D133/00 , C09D133/08 , C09D133/10 , C09D133/12 , C09D143/02
摘要： An aqueous coating composition for blocking stains and a method of using the coating composition is described. The coating composition includes an aqueous dispersion of a copolymer that is derived from a single stage emulsion polymerization of an ethylenically unsaturated nonionic monomer, greater than 0 and less than 1.5% by weight of an ethylenically unsaturated strong acid monomer or salt thereof, and greater than 1.5% and less than 3% by weight of methacrylic acid.
摘要翻译：描述了用于阻挡污渍的水性涂料组合物和使用该涂料组合物的方法。涂料组合物包括共聚物的水分散体，其衍生自烯键式不饱和非离子单体的单阶段乳液聚合，大于0且小于1.5重量％的烯属不饱和强酸单体或其盐，并且大于 1.5％且小于3％的甲基丙烯酸。

67. 发明授权

US09060754B2 Neuromodulation cryotherapeutic devices and associated systems and methods 有权
标题翻译：神经调节冷冻治疗装置及相关系统和方法
公开(公告)号：US09060754B2
公开(公告)日：2015-06-23
申请号：US13279328
申请日：2011-10-23
申请人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
发明人： Naomi Buckley , Benjamin J. Clark , Michael Cummins , Danny Donovan , Luke Hughes , Brian Kelly , Gary Kelly , Grace Kelly , John Kelly , Seamus Ledwith , Gwenda McMullin , Karun D. Naga , Stephen Nash , Eric Ryba , Fiachra Sweeney , Vincenzo Tilotta , Roman Turovskiy , Lana Woolley , Denise Zarins , Mark Gelfand , Mark S. Leung , Barry Mullins
IPC分类号： A61B18/02 , A61B18/00
CPC分类号： A61B18/02 , A61B2018/00214 , A61B2018/00232 , A61B2018/00255 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/0212
摘要： Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.
摘要翻译：本文公开了神经调节冷冻治疗装置及相关系统和方法。根据特定实施例构造的冷冻治疗装置包括细长轴和在轴的远端部分处的冷却组件。轴可以被配置为将血管内远端部分定位在肾动脉内或其他邻近肾动脉处的处置部位。冷冻治疗装置还可以包括被配置为将液体制冷剂运送到冷却组件的供应管腔。冷却组件可以包括与供应内腔流体连通的施加器，并且构造成当处于展开状态时，将冷冻治疗冷却递送到靠近目标部位的神经。

68. 发明授权

US08959016B2 Activating functions in processing devices using start codes embedded in audio 有权
标题翻译：使用嵌入在音频中的开始代码激活处理设备中的功能
公开(公告)号：US08959016B2
公开(公告)日：2015-02-17
申请号：US13341365
申请日：2011-12-30
申请人： William McKenna , Jason Bolles , John Kelly , John Stavropoulos , Alan Neuhauser , Wendell Lynch
发明人： William McKenna , Jason Bolles , John Kelly , John Stavropoulos , Alan Neuhauser , Wendell Lynch
IPC分类号： G10L15/00
CPC分类号： G10L19/018 , H04H20/93 , H04H60/31 , H04H60/37 , H04H60/58 , H04H60/65 , H04H2201/90
摘要： Apparatus, system and method for performing an action such as accessing supplementary data and/or executing software on a device capable of receiving multimedia are disclosed. After multimedia is received, a monitoring code is detected and a signature is extracted in response thereto from an audio portion of the multimedia. The ancillary code includes a plurality of code symbols arranged in a plurality of layers in a predetermined time period, and the signature is extracted from features of the audio of the multimedia. Supplementary data is accessed and/or software is executed using the detected code and/or signature.
摘要翻译：公开了用于在能够接收多媒体的设备上执行诸如访问补充数据和/或执行软件的动作的装置，系统和方法。在接收到多媒体之后，检测监视码并从多媒体的音频部分响应于此提取签名。辅助代码包括在预定时间段内以多层布置的多个代码符号，并且从多媒体的音频的特征中提取签名。使用检测到的代码和/或签名访问补充数据和/或执行软件。

69. 发明授权

US08542086B2 Conductive polymer electronic devices with surface mountable configuration and methods for manufacturing same 有权
标题翻译：具有表面可安装结构的导电聚合物电子器件及其制造方法
公开(公告)号：US08542086B2
公开(公告)日：2013-09-24
申请号：US12294675
申请日：2007-04-16
申请人： Gordon L. Bourns , Stelar Chu , Daniel E. Grindell , David Huang , John Kelly , Erik Meijer
发明人： Gordon L. Bourns , Stelar Chu , Daniel E. Grindell , David Huang , John Kelly , Erik Meijer
IPC分类号： H01C7/10
CPC分类号： H01C7/021 , H01C1/016 , H01C1/1406 , H01C1/1413 , H01C7/005 , H01C7/028 , H01C7/041 , H01C7/049 , H01C7/18 , H01C17/02 , H01C17/281 , Y10T29/49165
摘要： Surface-mountable conductive polymer electronic devices include at least one conductive polymer active layer laminated between upper and lower electrodes. Upper and lower insulation layers, respectively, sandwich the upper and lower electrodes. First and second planar conductive terminals are formed on the lower insulation layer. First and second cross-conductors are provided by plated through-hole vias, whereby the cross-conductors connect each of the electrodes to one of the terminals. Certain embodiments include two or more active layers, arranged in a vertically-stacked configuration and electrically connected by the cross-conductors and electrodes in parallel. Several embodiments include at least one cross-conductor having a chamfered or beveled entry hole through the upper insulation layer to provide enhanced adhesion between the cross-conductor and the insulation layer. Several methods for manufacturing the present surface-mountable conductive polymer electronic devices are also provided.
摘要翻译：表面安装导电聚合物电子器件包括层压在上电极和下电极之间的至少一个导电聚合物有源层。上下绝缘层分别夹着上下电极。第一和第二平面导电端子形成在下绝缘层上。第一和第二导体由电镀通孔通孔提供，由此将导体将每个电极连接到其中一个端子。某些实施方案包括两个或更多个有源层，其被布置成垂直堆叠的构造并且由交叉导体和电极并联电连接。几个实施例包括至少一个具有通过上绝缘层的倒角或斜面进入孔的交叉导体，以在交叉导体和绝缘层之间提供增强的粘合。还提供了用于制造本表面安装导电聚合物电子器件的几种方法。

70. 发明授权

US08486014B2 Spiral perfusion dilatation balloon for use in valvuloplasty procedure 有权
标题翻译：螺旋灌注扩张球囊用于瓣膜成形术
公开(公告)号：US08486014B2
公开(公告)日：2013-07-16
申请号：US13072689
申请日：2011-03-26
申请人： John Kelly , Brian Kelly , Herinaina Rabarimanantsoa-Jamous
发明人： John Kelly , Brian Kelly , Herinaina Rabarimanantsoa-Jamous
IPC分类号： A61M25/00
CPC分类号： A61M25/1002 , A61M25/1029 , A61M25/104 , A61M2025/1084 , A61M2025/1097
摘要： A balloon dilatation catheter for use in a valvuloplasty procedure includes a catheter shaft and a spiral perfusion balloon mounted thereon. The perfusion balloon is formed from an inflatable tube that is in fluid communication with a catheter shaft inflation lumen. The inflatable tube is coiled into a series of windings that in an inflated configuration form a cylindrical or hourglass profile. In the inflated configuration, inner surfaces of the coiled windings of the inflatable tube define a perfusion lumen to allow blood flow through the perfusion balloon. Adjacent windings may be secured together with a flexible adhesive and/or a support weave formed from one or more filaments of material that criss-crosses between the adjacent windings along substantially the entire length of the spiral perfusion balloon.
摘要翻译：用于瓣膜成形术的球囊扩张导管包括安装在其上的导管轴和螺旋灌注球囊。灌注气球由与导管轴膨胀腔流体连通的可充气管形成。可膨胀管被卷成一系列绕组，其以膨胀构型形成圆柱形或沙漏型。在充气构造中，可膨胀管的线圈绕组的内表面限定了灌注腔，以允许血液流过灌注球囊。相邻绕组可以用柔性粘合剂和/或由沿着螺旋形灌注气球的整个长度在相邻绕组之间交叉的一个或多个材料丝构成的支撑织物固定在一起。

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