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61. 发明申请

US20060173184A1 Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase 有权
公开(公告)号：US20060173184A1
公开(公告)日：2006-08-03
申请号：US11321710
申请日：2005-12-29
申请人： Richard Apodaca , J. Breitenbucher , Kanaka Pattabiraman , Mark Seierstad , Wei Xiao
发明人： Richard Apodaca , J. Breitenbucher , Kanaka Pattabiraman , Mark Seierstad , Wei Xiao
IPC分类号： C07D403/02
CPC分类号： C07D295/195 , C07D207/335 , C07D209/08 , C07D209/14 , C07D209/82 , C07D211/16 , C07D213/38 , C07D213/56 , C07D213/61 , C07D213/75 , C07D215/12 , C07D215/18 , C07D239/42 , C07D241/42 , C07D295/20 , C07D295/215 , C07D307/79 , C07D307/81 , C07D317/46 , C07D317/58 , C07D319/16 , C07D319/18 , C07D333/58 , C07D333/60 , C07D401/12 , C07D405/12 , C07D417/12
摘要： Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).

62. 发明授权

US07071191B2 Non-imidazole aryloxypiperidines 有权
公开(公告)号：US07071191B2
公开(公告)日：2006-07-04
申请号：US09922619
申请日：2001-08-06
申请人： Richard Apodaca , Nicholas I. Carruthers , Curt A. Dvorak , Chandravadan R. Shah , Wei Xiao
发明人： Richard Apodaca , Nicholas I. Carruthers , Curt A. Dvorak , Chandravadan R. Shah , Wei Xiao
IPC分类号： A61K31/5375 , C07D413/12
CPC分类号： C07D207/325 , A61K31/4402 , A61K31/4465 , A61K45/06 , C07C217/22 , C07C323/25 , C07C335/32 , C07D207/335 , C07D211/22 , C07D211/46 , C07D211/58 , C07D213/36 , C07D213/74 , C07D215/06 , C07D231/12 , C07D233/42 , C07D233/54 , C07D233/56 , C07D233/84 , C07D233/88 , C07D235/06 , C07D235/26 , C07D239/34 , C07D249/08 , C07D257/04 , C07D277/36 , C07D295/088 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/205 , C07D307/52 , C07D317/28 , C07D333/20 , C07D401/12 , C07D401/14 , C07D471/08 , A61K2300/00
摘要： Substituted non-imidazole aryloxypiperidine compounds, compositions containing them, and methods of making and using them to treat or prevent histamine-mediated conditions.

63. 发明申请

US20050216462A1 System and method for a snapshot query during database recovery 有权
标题翻译：数据库恢复期间快照查询的系统和方法
公开(公告)号：US20050216462A1
公开(公告)日：2005-09-29
申请号：US10812188
申请日：2004-03-29
申请人： Wei Xiao
发明人： Wei Xiao
IPC分类号： G06F7/00
CPC分类号： G06F17/30533 , G06F11/1471 , G06F11/2074 , G06F17/30362 , G06F17/30371 , Y10S707/99938 , Y10S707/99944 , Y10S707/99953
摘要： A method of performing a snapshot query in a database undergoing recovery allows access to the database during rollback or undo operations. The method includes allowing the query to detect whether a redo lock is present on a data item and if so, waiting until subsequent rollback operations release the lock. If another user has placed an exclusive lock on a data item of the database, the query may continue by reading a version of the data item form the version store. In an embodiment where a mirror database is used for recovery, the constant redo operations have an associated version store. Upon failover to the mirror database, queries may begin during the undo phase of recovery by allowing a query to read the version store of redo operations.
摘要翻译：在正在进行恢复的数据库中执行快照查询的方法允许在回滚或撤消操作期间访问数据库。该方法包括允许查询检测数据项上是否存在重做锁，如果是，则等待直到后续回滚操作释放锁。如果另一用户已经对数据库的数据项放置了排他锁，则可以通过从版本存储器读取数据项的版本来继续查询。在使用镜像数据库进行恢复的实施例中，常数重做操作具有关联的版本存储。在故障切换到镜像数据库时，可以在恢复的撤消阶段期间开始查询，方法是允许查询读取重做操作的版本存储。

64. 发明授权

US06884803B2 Phenylalkynes 有权
标题翻译：苯基炔
公开(公告)号：US06884803B2
公开(公告)日：2005-04-26
申请号：US10307870
申请日：2002-12-02
申请人： Richard Apodaca , Wei Xiao , Jill A. Jablonowski
发明人： Richard Apodaca , Wei Xiao , Jill A. Jablonowski
IPC分类号： C07D295/12 , A61K31/444 , A61K31/4453 , A61K31/4545 , A61K31/4709 , A61K31/496 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/541 , A61K45/00 , A61P1/08 , A61P11/06 , A61P25/00 , A61P25/06 , A61P25/08 , A61P25/18 , A61P25/20 , A61P25/28 , A61P27/14 , A61P27/16 , A61P37/08 , A61P43/00 , C07D203/12 , C07D209/14 , C07D209/16 , C07D211/14 , C07D211/22 , C07D211/44 , C07D211/46 , C07D211/60 , C07D211/62 , C07D211/66 , C07D213/38 , C07D215/06 , C07D215/12 , C07D239/42 , C07D273/00 , C07D273/01 , C07D277/04 , C07D295/02 , C07D295/03 , C07D295/073 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/205 , C07D401/04 , C07D401/12 , C07D471/10 , C07D491/10 , C07D491/113 , C07D403/06 , A61K31/495 , A61P25/24 , C07D295/04
CPC分类号： C07D239/42 , A61K31/444 , A61K31/4453 , A61K31/4709 , A61K31/5355 , A61K31/5377 , A61K31/541 , C07D203/12 , C07D209/16 , C07D211/14 , C07D211/22 , C07D211/44 , C07D211/46 , C07D211/60 , C07D211/62 , C07D213/38 , C07D215/06 , C07D273/00 , C07D277/04 , C07D295/02 , C07D295/03 , C07D295/073 , C07D295/096 , C07D295/112 , C07D295/135 , C07D295/205 , C07D401/04 , C07D401/12 , C07D471/10 , C07D491/10
摘要： Disclosed are substituted phenylalkynes of formula (I), wherein R1, R2, R3, R4, R5 and n are as defined, compositions containing them, and methods of making and using them to treat histamine-mediated conditions.
摘要翻译：公开了式（I）的取代的苯基炔，其中R 1，R 2，R 3，R 4， R 5和n如上所定义，含有它们的组合物，以及制备和使用它们来治疗组胺介导的病症的方法。

65. 发明申请

US20050085487A1 Heterocyclic compounds 审中-公开
标题翻译：杂环化合物
公开(公告)号：US20050085487A1
公开(公告)日：2005-04-21
申请号：US10961247
申请日：2004-10-08
申请人： Nicholas Carruthers , Wenying Chai , Curt Dvorak , James Edwards , Cheryl Grice , Jill Jablonowski , Lars Karlsson , Haripada Khatuya , Jennifer Kreisberg , Annette Kwok , Timothy Lovenberg , Kiev Ly , Barbara Pio , Chandravadan Shah , Siquan Sun , Robin Thurmond , Jianmei Wei , Wei Xiao
发明人： Nicholas Carruthers , Wenying Chai , Curt Dvorak , James Edwards , Cheryl Grice , Jill Jablonowski , Lars Karlsson , Haripada Khatuya , Jennifer Kreisberg , Annette Kwok , Timothy Lovenberg , Kiev Ly , Barbara Pio , Chandravadan Shah , Siquan Sun , Robin Thurmond , Jianmei Wei , Wei Xiao
IPC分类号： C07D307/84 , A61K31/496 , A61P1/04 , A61P7/00 , A61P9/06 , A61P17/06 , A61P19/02 , A61P25/28 , A61P29/00 , A61P37/04 , A61P37/06 , A61P37/08 , A61P43/00 , C07D209/42 , C07D401/12 , C07D403/06 , A61K31/454 , C07D413/02 , C07D417/02 , C07D43/02
CPC分类号： C07D401/12 , A61K31/496 , C07D209/42
摘要： Heterocyclic compounds and methods of making them and using them.
摘要翻译：杂环化合物及其制备方法和使用方法。

66. 发明授权

US06587881B1 Software server usage governor 有权
标题翻译：软件服务器使用总监
公开(公告)号：US06587881B1
公开(公告)日：2003-07-01
申请号：US09289054
申请日：1999-04-09
申请人： Sameet Agarwal , Wei Xiao , Michael Zwilling
发明人： Sameet Agarwal , Wei Xiao , Michael Zwilling
IPC分类号： G06F1516
CPC分类号： G06F9/505 , G06F11/3433 , G06F11/3438 , G06F11/3452 , G06F2201/87 , G06F2201/88
摘要： A system and method for controlling usage of a particular software program in a computer network environment is disclosed. The invention operates by controlling the throughput of the software as it executes on a server computer. In particular, the invention monitors the number of active requests to the software. If the number of active requests exceeds a predefined number, the software throughput on the server (e.g., requests completed per minute) is artificially restricted. As such, the present invention continues to allow further connections to the software but intentionally restricts further use by inhibiting the throughput for all connections to the software. Preferably, the present invention continues to allow the predefined number of active requests to be exceeded, but as more requests are made, the overall performance of software progressively degrades.
摘要翻译：公开了一种用于控制计算机网络环境中特定软件程序的使用的系统和方法。本发明通过在服务器计算机上执行时控制软件的吞吐量来操作。特别地，本发明监视对软件的活动请求的数量。如果活动请求的数量超过预定义的数量，则服务器上的软件吞吐量（例如，每分钟完成的请求）被人为限制。因此，本发明继续允许与软件的进一步连接，而是有意地通过禁止对软件的所有连接的吞吐量来限制进一步的使用。优选地，本发明继续允许超过预定数量的活动请求，但是随着更多请求，软件的整体性能逐渐降低。

67. 发明授权

US08914497B1 System and method for throttling service requests having non-uniform workloads 有权
标题翻译：用于限制具有不均匀工作负载的服务请求的系统和方法
公开(公告)号：US08914497B1
公开(公告)日：2014-12-16
申请号：US13327620
申请日：2011-12-15
申请人： Wei Xiao , David A. Lutz , Timothy Andrew Rath , Maximiliano Maccanti , Miguel Mascarenhas Filipe , David C. Yanacek
发明人： Wei Xiao , David A. Lutz , Timothy Andrew Rath , Maximiliano Maccanti , Miguel Mascarenhas Filipe , David C. Yanacek
IPC分类号： G06F15/173 , G06F11/00
CPC分类号： H04L67/16 , G06F9/505 , G06F11/3433 , G06F11/3452 , G06F11/3485 , G06F2201/81 , G06F2209/504 , H04L67/42 , Y02D10/22
摘要： A system that provides services to clients may receive and service requests, various ones of which may require different amounts of work. The system may determine whether it is operating in an overloaded or underloaded state based on a current work throughput rate, a target work throughput rate, a maximum request rate, or an actual request rate, and may dynamically adjust the maximum request rate in response. For example, if the maximum request rate is being exceeded, the maximum request rate may be raised or lowered, dependent on the current work throughput rate. If the target or committed work throughput rate is being exceeded, but the maximum request rate is not being exceeded, a lower maximum request rate may be proposed. Adjustments to the maximum request rate may be made using multiple incremental adjustments. Service request tokens may be added to a leaky token bucket at the maximum request rate.
摘要翻译：向客户端提供服务的系统可以接收和服务请求，其中各种可能需要不同的工作量。系统可以基于当前工作吞吐率，目标工作吞吐率，最大请求速率或实际请求速率来确定其是否处于过载或欠载状态，并且可以动态地调整响应的最大请求速率。例如，如果超过最大请求速率，则可以根据当前的工作吞吐率来提高或降低最大请求速率。如果超过了目标或提交的工作吞吐率，但不超过最大请求率，则可能会提出较低的最大请求率。可以使用多个增量调整来调整最大请求率。可以以最大请求率将服务请求令牌添加到泄漏令牌桶中。

68. 发明授权

US08886523B2 Audio decoding based on audio class with control code for post-processing modes 有权
标题翻译：基于音频类的音频解码，具有后处理模式的控制码
公开(公告)号：US08886523B2
公开(公告)日：2014-11-11
申请号：US12893526
申请日：2010-09-29
申请人： David Sylvain Thierry Virette , Yang Gao , Wei Xiao
发明人： David Sylvain Thierry Virette , Yang Gao , Wei Xiao
IPC分类号： G10L19/02 , G10L21/02 , G10L19/26 , G10L25/18
CPC分类号： G10L19/00 , G10L19/26 , G10L25/18
摘要： In accordance with an embodiment, a method of generating an encoded audio signal, the method includes estimating a time-frequency energy of an input audio signal from a time-frequency filter bank, computing a global variance of the time-frequency energy, determining a post-processing method according to the global variance, and transmitting an encoded representation of the input audio signal along with an indication of the determined post-processing method.
摘要翻译：根据实施例，一种生成编码音频信号的方法，所述方法包括估计来自时频滤波器组的输入音频信号的时频能量，计算时频能量的全局方差，确定根据全局方差的后处理方法，以及输出音频信号的编码表示以及所确定的后处理方法的指示。

69. 发明授权

US08530476B2 Piperazinyl and piperidinyl ureas as modulators of fatty acid amide hydrolase 有权
公开(公告)号：US08530476B2
公开(公告)日：2013-09-10
申请号：US12557650
申请日：2009-09-11
申请人： Richard Apodaca , J. Guy Breitenbucher , Kanaka Pattabiraman , Mark Seierstad , Wei Xiao
发明人： Richard Apodaca , J. Guy Breitenbucher , Kanaka Pattabiraman , Mark Seierstad , Wei Xiao
IPC分类号： A61K31/497 , C07D403/00 , C07D405/06 , C07D401/06
CPC分类号： C07D295/195 , C07D207/335 , C07D209/08 , C07D209/14 , C07D209/82 , C07D211/16 , C07D213/38 , C07D213/56 , C07D213/61 , C07D213/75 , C07D215/12 , C07D215/18 , C07D239/42 , C07D241/42 , C07D295/20 , C07D295/215 , C07D307/79 , C07D307/81 , C07D317/46 , C07D317/58 , C07D319/16 , C07D319/18 , C07D333/58 , C07D333/60 , C07D401/12 , C07D405/12 , C07D417/12
摘要： Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).

70. 发明授权

US08380526B2 Method, device and system for enhancement layer signal encoding and decoding 有权
标题翻译：用于增强层信号编码和解码的方法，装置和系统
公开(公告)号：US08380526B2
公开(公告)日：2013-02-19
申请号：US13111834
申请日：2011-05-19
申请人： Chen Hu , Zexin Liu , Lei Miao , Longyin Chen , Qing Zhang , Wei Xiao , Herve Marcel Taddei
发明人： Chen Hu , Zexin Liu , Lei Miao , Longyin Chen , Qing Zhang , Wei Xiao , Herve Marcel Taddei
IPC分类号： G10L19/00 , G10L19/12
CPC分类号： G10L21/00 , G10L19/24
摘要： A method, device and system for signal encoding and decoding are disclosed. The method includes: encoding a core layer signal to obtain a core layer signal code; selecting an enhancement sample point that requires enhancement layer signal encoding according to the core layer signal code and the number of bits that can be used by an enhancement layer; obtaining an enhancement layer signal code of the enhancement sample point; and outputting a bit stream, where the bit stream includes the core layer signal code and the enhancement layer signal code. In embodiments of the present invention, according to the number of bits that can be used by the enhancement layer, the enhancement sample point that requires enhancement layer signal encoding is selected; the enhancement layer signal of the selected enhancement sample point is encoded and decoded; when no sufficient bits are available for the enhancement layer, the enhancement quality of the core layer can be improved.
摘要翻译：公开了用于信号编码和解码的方法，装置和系统。该方法包括：编码核心层信号以获得核心层信号码; 选择需要根据核心层信号码的增强层信号编码和增强层可以使用的位数的增强采样点; 获得增强采样点的增强层信号码; 并输出比特流，其中比特流包括核心层信号码和增强层信号码。在本发明的实施例中，根据增强层可以使用的比特数，选择需要增强层信号编码的增强采样点; 所选择的增强采样点的增强层信号被编码和解码; 当没有足够的比特可用于增强层时，可以提高核心层的增强质量。

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