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61. 发明授权

US09375215B2 Device for rapid repair of body conduits 有权
标题翻译：快速修复身体导管的装置
公开(公告)号：US09375215B2
公开(公告)日：2016-06-28
申请号：US11624513
申请日：2007-01-18
申请人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61F2/94 , A61B17/11 , A61F2/07 , A61F2/97 , A61B17/06 , A61F2/06 , A61F2/30 , A61F2/89
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.
摘要翻译：自扩张的支架移植物以径向压实状态提供用于植入，并且优选地由约束护套保持，其用于临时或永久性修复包括血管的受损部分或全部横断的身体导管。它可以在直接可视化下使用，以快速停止或显着减少来自这些受损血管的血液损失，并迅速重建在损伤部位远端的灌注。该设备通常将在急诊室条件下植入，但也由经过培训的医疗技术人员在现场使用。在装置的一端通过伤口进入插入血管之后，展开优选地通过定向释放约束护套从朝向装置长度方向移动的方向从装置端开始。在优选实施例中，装置的两个相对的端部可单独地从用于插入容器的压实的小直径扩展到可干燥地配合到容器的一部分中的较大的直径。

62. 发明授权

US08906081B2 Stented vascular graft 有权
标题翻译：支架血管移植
公开(公告)号：US08906081B2
公开(公告)日：2014-12-09
申请号：US11854735
申请日：2007-09-13
申请人： Edward H. Cully , Deenu Kanjickal , Bret J. Kilgrow , Larry J. Kovach , Timothy T. Stringer
发明人： Edward H. Cully , Deenu Kanjickal , Bret J. Kilgrow , Larry J. Kovach , Timothy T. Stringer
IPC分类号： A61F2/06 , A61F2/07 , A61F2/97 , A61F2/89 , A61F2/95
CPC分类号： A61F2/07 , A61F2/06 , A61F2/064 , A61F2/82 , A61F2/852 , A61F2/86 , A61F2/89 , A61F2/97 , A61F2002/065 , A61F2002/828 , A61F2002/9511 , A61F2002/9522 , A61F2210/0014 , A61F2230/0069 , A61F2240/001 , A61F2250/0067 , Y10T29/49885 , Y10T29/49901
摘要： A vascular graft incorporating a stent into a portion of its length. While various materials may be used for the vascular graft, the graft is preferably an ePTFE graft. The stent is preferably a self-expanding stent, although it may alternatively be a balloon expandable stent. The vascular graft preferably has a continuous inner tubular liner that extends between the opposing ends of the graft and provides a continuous luminal surface for blood contact that is uninterrupted by seams or joints. The length portion of the graft that does not include the stent has a greater wall thickness than does the portion including the stent.
摘要翻译：将支架结合到其长度的一部分中的血管移植物。虽然各种材料可用于血管移植物，但移植物优选为ePTFE移植物。支架优选是自扩张支架，尽管它可以替代地是球囊扩张支架。血管移植物优选具有在移植物的相对端之间延伸的连续的内部管状衬垫，并且提供用于血液接触的连续腔表面，其不受接缝或关节的中断。不包括支架的移植物的长度部分具有比包括支架的部分更大的壁厚。

63. 发明申请

US20130204345A1 EVERTABLE SHEATH DEVICES, SYSTEMS, AND METHODS 审中-公开
标题翻译：可靠的设备，系统和方法
公开(公告)号：US20130204345A1
公开(公告)日：2013-08-08
申请号：US13571296
申请日：2012-08-09
申请人： Edward H. Cully , Craig W. Irwin , James D. Silverman
发明人： Edward H. Cully , Craig W. Irwin , James D. Silverman
IPC分类号： A61F2/958
CPC分类号： A61F2/958 , A61F2/966 , A61F2002/826 , A61F2002/9522 , Y10T29/49863
摘要： The present disclosure comprises devices, systems, and methods having an inverted sheath configured to cover, and in some instances constrain, a medical device and to retract through eversion, thus enabling the deployment of medical device at the treatment site. A constraining sheath can evert hydraulically. A constraining sheath can be configured to neck down a medical device to achieve a lower delivery profile. Furthermore, a constraining sheath can comprise a balloon to expand or positionally or structurally adjust a medical device.
摘要翻译：本公开包括具有倒置护套的装置，系统和方法，其被配置为覆盖医疗装置并且在某些情况下约束医疗装置并且通过外翻退回，从而能够在治疗部位部署医疗装置。约束护套可以液压地切换。约束护套可以被配置为使医疗装置颈缩以实现较低的输送轮廓。此外，约束护套可以包括用于扩张或定位或结构地调整医疗装置的气囊。

64. 发明授权

US08491613B2 Aortic dissection septal cutting tool 有权
标题翻译：主动脉夹层中隔切割工具
公开(公告)号：US08491613B2
公开(公告)日：2013-07-23
申请号：US12620360
申请日：2009-11-17
申请人： Cody L. Bliss , Edward H. Cully , Joel M. Greene , Joshua J. Lovekamp , Michael C. Nilson , Himanshu Jagdish Patel , David M. Williams , William P. Witort
发明人： Cody L. Bliss , Edward H. Cully , Joel M. Greene , Joshua J. Lovekamp , Michael C. Nilson , Himanshu Jagdish Patel , David M. Williams , William P. Witort
IPC分类号： A61B17/22
CPC分类号： A61B17/320016 , A61B17/3201 , A61B17/32075 , A61B18/1492 , A61B2017/00778 , A61B2017/22039 , A61B2017/22052 , A61B2017/22069 , A61M25/003 , A61M2025/0037
摘要： The present invention relates to medical cutting tools for treating aortic septal dissections. The cutting tool is provided with a delivery catheter and has a remotely actuated cutting blade or cutting wire component. The cutting tool is provided with at least one displacement element. The displacement element assists in placement of the cutting tool at a desired location. The displacement element also assists in maintaining contact between the cutting blade and tissue being cut.
摘要翻译：本发明涉及用于治疗主动脉间隔解剖的医疗切割工具。切割工具设置有输送导管，并且具有远程致动的切割刀片或切割线部件。切割工具设置有至少一个位移元件。位移元件有助于将切割工具放置在期望的位置。位移元件还有助于保持切割刀片和被切割的组织之间的接触。

65. 发明授权

US08425584B2 Expandable covered stent with wide range of wrinkle-free deployed diameters 有权
标题翻译：可扩展的支架具有广泛的无皱纹部署直径
公开(公告)号：US08425584B2
公开(公告)日：2013-04-23
申请号：US11408474
申请日：2006-04-21
申请人： Edward H. Cully , Michael J. Vonesh
发明人： Edward H. Cully , Michael J. Vonesh
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/915 , A61F2002/075 , Y10T29/49908 , Y10T29/49911 , Y10T29/49913
摘要： An improved stent-graft device is provided that delivers a smooth flow surface over a range of operative expanded diameters by applying a unique cover material to the stent through a technique that allows the cover to become wrinkle-free prior to reaching fully deployed diameter. The unique cover material then allows the device to continue to expand to a fully deployed diameter while maintaining a smooth and coherent flow surface throughout this additional expansion. Employed with a self-expanding device, when the device is unconstrained from a compacted diameter it will self-expand up to a fully deployed diameter with the graft being substantially wrinkle-free over diameters ranging from about 30-50% to 100% of the fully deployed diameter.
摘要翻译：提供了一种改进的支架移植装置，其通过使覆盖物在达到完全展开的直径之前变得无皱纹的技术，通过将独特的覆盖材料施加到支架上，在一定范围的工作扩张直径上提供平滑的流动表面。独特的覆盖材料然后允许设备继续扩展到完全展开的直径，同时在整个这种额外的扩展中保持平滑和一致的流动表面。采用自扩张装置，当装置不受压实直径的限制时，其将自膨胀直至完全展开的直径，其中移植物基本上无皱纹，直径范围为约30-50％至100％完全展开直径。

66. 发明申请

US20130041404A1 Heart Occlusion Devices 有权
标题翻译：心脏闭塞装置
公开(公告)号：US20130041404A1
公开(公告)日：2013-02-14
申请号：US13571046
申请日：2012-08-09
申请人： Zahid Amin , Edward H. Cully , Warren Cutright , Coby Larsen , Steven J. Masters , Edward Emil Shaw
发明人： Zahid Amin , Edward H. Cully , Warren Cutright , Coby Larsen , Steven J. Masters , Edward Emil Shaw
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B17/12031 , A61B17/12145 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867
摘要： Devices for occluding an aperture in tissue or a vessel comprise a first flexible wire and a second flexible wire. Each of the first and second wires is comprised of a shape memory material. Each of the first and second wires is shaped into first and second geometric forms such that the first geometric form of the first wire and the first geometric form of the second wire form a first plate in a first plane, and the second geometric form of the first wire and the second geometric form of the second wire form a second plate in a second plane that is parallel to and remote from the first plane. The first and second plates are separated by a waist formed from two portions of the first wire and two portions of the second wire. Methods for occluding an aperture in tissue or a vessel using such devices are also provided.
摘要翻译：用于封闭组织或容器中的孔的装置包括第一柔性线和第二柔性线。第一和第二导线中的每一个由形状记忆材料构成。第一和第二电线中的每一个被成形为第一和第二几何形状，使得第一线的第一几何形状和第二线的第一几何形状在第一平面中形成第一板，并且第二几何形式的第一线和第二线的第二几何形状在与第一平面平行并远离第二平面的第二平面中形成第二板。第一和第二板由由第一线的两个部分和第二线的两个部分形成的腰部分开。还提供了使用这种装置封闭组织或容器中的孔的方法。

67. 发明授权

US08313503B2 Endoluminal devices 有权
标题翻译：腔内装置
公开(公告)号：US08313503B2
公开(公告)日：2012-11-20
申请号：US10907975
申请日：2005-04-22
申请人： Edward H. Cully , K. Jason Nackard , Michael J. Vonesh
发明人： Edward H. Cully , K. Jason Nackard , Michael J. Vonesh
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61B17/12109 , A61F2/013 , A61F2/91 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0015 , A61F2230/005 , A61F2230/0067 , A61F2230/0069 , A61F2230/0076 , A61F2230/008 , A61F2230/0091 , A61F2230/0093
摘要： A seamless, self-expanding implantable device having a low profile is disclosed along with methods of making and using the same. The implantable device includes a frame cut out of a single piece of material that is formed into a three-dimensional shape. The implantable device may comprise an embolic filter, stent, or other implantable structure. The present invention also allows complicated frame structures to be easily formed from planar sheets of starting material, such as through laser cutting, stamping, photo-etching, or other cutting techniques.
摘要翻译：公开了具有低轮廓的无缝的，自膨胀的可植入装置及其制造和使用方法。可植入装置包括由形成为三维形状的单块材料切出的框架。可植入装置可以包括栓塞过滤器，支架或其它可植入结构。本发明还允许通过激光切割，冲压，光蚀刻或其它切割技术从起始材料的平面薄片容易地形成复杂的框架结构。

68. 发明申请

US20120172927A1 LEFT ATRIAL APPENDAGE OCCLUSIVE DEVICES 有权
标题翻译：左侧ATRIAL APPENDAGE OCCLUSIVE设备
公开(公告)号：US20120172927A1
公开(公告)日：2012-07-05
申请号：US13293803
申请日：2011-11-10
申请人： Benjamin D. Campbell , Edward H. Cully , Jeffrey B. Duncan , Nichlas L. Helder , Coby C. Larsen , Steven J. Masters , Scot K. Mathena , Thomas R. McDaniel , Edward E. Shaw
发明人： Benjamin D. Campbell , Edward H. Cully , Jeffrey B. Duncan , Nichlas L. Helder , Coby C. Larsen , Steven J. Masters , Scot K. Mathena , Thomas R. McDaniel , Edward E. Shaw
IPC分类号： A61B17/03
CPC分类号： A61B17/1215 , A61B17/0057 , A61B17/12122 , A61B17/12145 , A61B17/12172 , A61B2017/00592 , A61B2017/00597 , A61B2017/00615 , A61B2017/00623 , A61B2017/00632 , A61B2017/1205
摘要： An occlusive device for left atrial appendage occlusion that has a membrane component configured to inhibit passage of blood and an expandable frame formed from a plurality of wires having a cupped occlusive component at least partially covered with the membrane component, one or more anchors with looped ends and a hub component. The occlusive device can be delivered percutaneously. The occlusive device is useful in the occlusion of the left atrial appendage.
摘要翻译：一种用于左心耳闭塞的闭塞装置，其具有构造成阻止血液通过的膜组件和由具有至少部分地被膜组件覆盖的杯状封闭组件的多根丝线形成的可扩张框架，一个或多个具有环形端部的锚固件和集线器组件。闭塞装置可以经皮递送。闭塞装置可用于闭塞左心耳。

69. 发明申请

US20120109283A1 STENT HAVING ADJACENT ELEMENTS CONNECTED BY FLEXIBLE WEBS 有权
标题翻译：具有由柔性织物连接的相邻元件的固定元件
公开(公告)号：US20120109283A1
公开(公告)日：2012-05-03
申请号：US13349346
申请日：2012-01-12
申请人： Dustin C. Burkart , Edward H. Cully , Jeffrey B. Duncan , Cody L. Hartman , James D. Silverman
发明人： Dustin C. Burkart , Edward H. Cully , Jeffrey B. Duncan , Cody L. Hartman , James D. Silverman
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2/07 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/915 , A61F2002/075 , A61F2002/826 , A61F2002/828 , A61F2002/91558
摘要： A stent incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent, spaced-apart stent elements. Preferably the spaced-apart adjacent stent elements are the result of forming the stent from a helically wound serpentine wire having space provided between adjacent windings. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used. The connecting elements are typically web-shaped and result from creating slits or apertures in a covering of graft material applied to the stent and then, for example, applying heat to cause the slits or apertures to enlarge. The remaining graft material forms the interconnecting webs between the adjacent stent elements.
摘要翻译：支架将柔性，优选聚合的连接元件结合到支架中，其中这些元件连接相邻的间隔开的支架元件。优选地，间隔开的相邻支架元件是由具有设置在相邻绕组之间的空间的螺旋形缠绕蛇形线形成支架的结果。还可以使用其它支架形式，例如多个，单独间隔开的环形或互连的支架元件。连接元件通常是网状的，并且是通过在施加到支架上的移植材料的覆盖物中产生狭缝或孔，并且然后例如施加热量以使狭缝或孔径增大。剩余的移植材料形成相邻支架元件之间的互连网。

70. 发明申请

US20120065652A1 ANASTOMOTIC DEVICES AND METHODS 有权
标题翻译：分析装置和方法
公开(公告)号：US20120065652A1
公开(公告)日：2012-03-15
申请号：US13229540
申请日：2011-09-09
申请人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
发明人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
IPC分类号： A61B17/11 , A61F2/06
CPC分类号： A61M1/3655 , A61B17/08 , A61B17/11 , A61B2017/1135 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/8486 , A61F2230/0067 , A61F2230/0069
摘要： Exemplary embodiments comprise AV fistulas and other anastomotic devices for creating new or reinforcing existing side-branch vessels, and/or bridging neighboring vessels together. An exemplary embodiment may comprise a sidewall port, such as a flanged sidewall port, and/or flow frame design, such as a partially bare, flexible stent or a whisk, for purposes of creating a transmural flow. Another exemplary embodiment may comprise a compliant vessel support to aid in the transition from device to vessel and/or vessel to device, and to promote vessel dilation.
摘要翻译：示例性实施例包括用于创建新的或加强现有侧支血管，和/或将邻近血管桥接在一起的AV瘘和其它吻合装置。为了产生透壁流，示例性实施例可以包括侧壁端口，例如法兰侧壁端口和/或流动框架设计，例如部分裸露的柔性支架或者搅拌器。另一个示例性实施例可以包括顺应容器支撑件，以帮助从装置到容器和/或容器到装置的过渡，并且促进血管扩张。

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