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1. 发明申请

US20110230951A1 DEVICE FOR RAPID REPAIR OF BODY CONDUITS 有权
标题翻译：身体快速修复装置
公开(公告)号：US20110230951A1
公开(公告)日：2011-09-22
申请号：US13149696
申请日：2011-05-31
申请人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.
摘要翻译：自扩张的支架移植物以径向压实状态提供用于植入，并且优选地由约束护套保持，其用于临时或永久性修复包括血管的受损部分或全部横断的身体导管。它可以在直接可视化下使用，以快速停止或显着减少来自这些受损血管的血液损失，并迅速重建在损伤部位远端的灌注。该设备通常将在急诊室条件下植入，但也由经过培训的医疗技术人员在现场使用。在装置的一端通过伤口进入插入血管之后，展开优选地通过定向释放约束护套从朝向装置长度方向移动的方向从装置端开始。在优选实施例中，装置的两个相对的端部可单独地从用于插入容器的压实的小直径扩展到可干燥地配合到容器的一部分中的较大的直径。

2. 发明授权

US09381018B2 Device for rapid repair of body conduits 有权
公开(公告)号：US09381018B2
公开(公告)日：2016-07-05
申请号：US13149696
申请日：2011-05-31
申请人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61F2/84 , A61B17/11 , A61F2/07 , A61F2/97 , A61B17/06 , A61F2/06 , A61F2/30 , A61F2/89
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.

3. 发明授权

US09375215B2 Device for rapid repair of body conduits 有权
标题翻译：快速修复身体导管的装置
公开(公告)号：US09375215B2
公开(公告)日：2016-06-28
申请号：US11624513
申请日：2007-01-18
申请人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Edward H. Cully , Jeffrey B. Duncan , Keith M. Flury , Paul D. Goodman , Wayne D. House , Vrad W. Levering , Philip P. Off , Daniel M. O'Shea , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61F2/94 , A61B17/11 , A61F2/07 , A61F2/97 , A61B17/06 , A61F2/06 , A61F2/30 , A61F2/89
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.
摘要翻译：自扩张的支架移植物以径向压实状态提供用于植入，并且优选地由约束护套保持，其用于临时或永久性修复包括血管的受损部分或全部横断的身体导管。它可以在直接可视化下使用，以快速停止或显着减少来自这些受损血管的血液损失，并迅速重建在损伤部位远端的灌注。该设备通常将在急诊室条件下植入，但也由经过培训的医疗技术人员在现场使用。在装置的一端通过伤口进入插入血管之后，展开优选地通过定向释放约束护套从朝向装置长度方向移动的方向从装置端开始。在优选实施例中，装置的两个相对的端部可单独地从用于插入容器的压实的小直径扩展到可干燥地配合到容器的一部分中的较大的直径。

4. 发明申请

US20110276012A1 PUNCTURABLE CATHETER 有权
标题翻译：可拆卸导管
公开(公告)号：US20110276012A1
公开(公告)日：2011-11-10
申请号：US13186198
申请日：2011-07-19
申请人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61M25/00
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

5. 发明授权

US07556641B2 Deployment system for an expandable device 有权
标题翻译：可扩展设备的部署系统
公开(公告)号：US07556641B2
公开(公告)日：2009-07-07
申请号：US10892934
申请日：2004-07-16
申请人： Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958 , A61F2/97 , A61F2002/9511
摘要： The present invention is directed to a deployment system for an endoluminal device. The deployment system includes a confining sheath placed around a compacted endoluminal device. A deployment line is provided in the system that is an integral extension of the sheath. As the deployment line is actuated, the sheath retracts from around the compacted endoluminal device. As the sheath retracts from around the endoluminal device, material from the sheath may be converted into deployment line. Once the sheath is retracted from around the compacted endoluminal device, the endoluminal device expands in configuration and repairs vascular or cardiac structures of an implant recipient. Any remaining sheath material is removed from the implantation site along with the deployment line. The deployment system also includes an endo-prosthesis mounting member placed between the endoluminal device and an underlying catheter. The endo-prosthesis mounting member serves to cushion and retain the endoluminal device when constrained by the sheath and may assist in expansion of the endoluminal device when unconstrained by the sheath.The present invention is also directed to a deployment system having a deployment assembly that simultaneously expands an endo-prosthesis mounting member while removing a sheath from an expandable medical device.
摘要翻译：本发明涉及一种用于腔内装置的部署系统。部署系统包括围绕压实的腔内装置放置的限制鞘。在系统中提供了一个部署线，该线是护套的整体延伸。随着部署线被致动，护套从紧凑的腔内装置周围缩回。当护套从内腔装置周围缩回时，来自护套的材料可以被转换成展开线。一旦护套从紧凑的腔内装置周围缩回，腔内装置在构型上扩张并修复植入物接受者的血管或心脏结构。任何剩余的护套材料与植入线一起从植入部位移除。所述展开系统还包括放置在腔内装置和下面的导管之间的内腔假体安装构件。假体内固定构件用于在被护套约束时缓冲和保持内腔装置，并且可以在不受护套约束时有助于内腔装置的膨胀。本发明还涉及一种具有展开组件的展开系统，所述展开组件在从可扩张医疗装置移除护套的同时同时展开内衣假体安装构件。

6. 发明授权

US09433745B2 Puncturing tool for puncturing catheter shafts 有权
标题翻译：穿刺导管轴穿刺工具
公开(公告)号：US09433745B2
公开(公告)日：2016-09-06
申请号：US10868252
申请日：2004-06-14
申请人： Edward H. Cully , Sherif A. Eskaros , Keith M. Flury , James W. Mann , Benjamin M. Trapp , Michael J. Vonesh
发明人： Edward H. Cully , Sherif A. Eskaros , Keith M. Flury , James W. Mann , Benjamin M. Trapp , Michael J. Vonesh
IPC分类号： A61M5/178 , A61M25/00 , A61M25/01
CPC分类号： A61M25/00 , A61M2025/0175
摘要： Puncturing tools that cause an aperture to be pierced through the wall of a guidewire lumen of a catheter shaft at a location at which it is desired to have a guidewire exit the guidewire lumen.
摘要翻译：刺穿工具，其导致孔被刺穿穿过导管轴的导丝管腔的壁，在期望导丝线离开导丝管腔的位置处。

7. 发明授权

US08016752B2 Puncturable catheter 有权
标题翻译：可导管
公开(公告)号：US08016752B2
公开(公告)日：2011-09-13
申请号：US10402083
申请日：2003-03-28
申请人： Joseph R. Armstrong , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： Joseph R. Armstrong , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61B1/12 , A61M29/00
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅仅覆盖导管轴的直接邻近导丝管腔的外部的部分的单独部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

8. 发明授权

US09119937B2 Puncturable catheter 有权
标题翻译：可导管
公开(公告)号：US09119937B2
公开(公告)日：2015-09-01
申请号：US13186198
申请日：2011-07-19
申请人： Joseph R. Armstrong , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： Joseph R. Armstrong , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61M25/00 , A61M25/10 , A61F2/958 , A61M25/01
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

9. 发明申请

US20100137928A1 IMPLANTABLE LEAD 有权
标题翻译：可塑性铅
公开(公告)号：US20100137928A1
公开(公告)日：2010-06-03
申请号：US12605302
申请日：2009-10-23
申请人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61N1/05 , H01R43/16 , H01R24/04
CPC分类号： A61N1/05 , A61N1/0563 , Y10T29/49204
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.
摘要翻译：高度灵活的可植入引线，提供更好的灵活性，疲劳寿命和疲劳和耐磨性，提高了可靠性，有效的电极组织接触具有小直径和低抽提时的组织损伤风险。在一个实施例中，引线设置有除颤电极和起搏/感测电极。对于除颤/起搏引线，引线直径可以小至六法国或更小。该结构采用螺旋缠绕导体。对于并入多个独立导体的引线，许多螺旋缠绕导体以多丝状关系布置。优选地，每个导体是在其长度的大约中间部分未绝缘的导线的长度以产生电极，其中导体在大约中间的长度处折叠成一半，以形成构成平行导体的第一和第二长度段。

10. 发明授权

US08364281B2 Implantable lead 有权
公开(公告)号：US08364281B2
公开(公告)日：2013-01-29
申请号：US12605302
申请日：2009-10-23
申请人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0563 , Y10T29/49204
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.

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