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    • 61. 发明授权
    • Antimicrobial resin cured rubber articles and prevulcanized compositions
    • 抗菌树脂固化橡胶制品和预硫化组合物
    • US06846871B2
    • 2005-01-25
    • US10424025
    • 2003-04-25
    • Bhawan PatelDavid L. Morris
    • Bhawan PatelDavid L. Morris
    • C08K3/00C08K3/08C08K3/22
    • C08K3/08C08K3/015C08K3/22C08L21/00
    • This invention relates to certain non-silicone resin cured rubber articles that are made from at least a majority by weight of non-silicone vulcanized rubber that include silver-based compounds to provide highly desirable long-term antimicrobial characteristics within the cured rubber articles. Such articles are in either solid or blown (foam or sponge) state (or combinations of both in multilayered forms) and can be utilized in a variety of different applications. This invention encompasses the presence of non-sulfur-based curing systems and agents, such as resin curing, that permit vulcanization and do not irreversibly bind silver ions thereto, thereby resulting in long-term antimicrobial performance of the ultimate rubber article itself. This invention also encompasses certain non-silicone pre-vulcanized raw rubber formulations made from at least a majority by weight of non-silicone rubber that include silver-based components to provide highly desirable long-term antimicrobial characteristics within the ultimate resin cured rubber articles made therefrom.
    • 本发明涉及由至少大部分重量的非硅氧烷硫化橡胶制成的某些非硅树脂固化橡胶制品,其包括银基化合物,以在固化的橡胶制品内提供高度期望的长期抗菌特性。 这样的制品是固体或吹制(泡沫或海绵)状态(或两者的组合形式),可用于各种不同的应用。 本发明包括非硫基固化体系和诸如树脂固化的试剂的存在,其允许硫化并且不会不可逆地将银离子结合到其上,从而导致最终橡胶制品本身的长期抗微生物性能。 本发明还包括由至少大部分重量的非硅橡胶制成的某些非硅氧烷预硫化生橡胶配方,其包括银基组分,以在最终树脂固化橡胶制品中提供非常期望的长期抗微生物特性 由此。
    • 62. 发明授权
    • Colored antimicrobial vulcanized rubber articles
    • US06638993B2
    • 2003-10-28
    • US10015878
    • 2001-12-12
    • Bhawan PatelDavid L. MorrisGeoffrey HaasWilliam O. Burke, III
    • Bhawan PatelDavid L. MorrisGeoffrey HaasWilliam O. Burke, III
    • C08K509
    • C08K3/34C08K3/015C08K5/0058C08L21/00C08L23/16
    • Certain non-silicone vulcanized rubber articles made from at least a majority by weight of ethylene-propylene-diene modified (terpolymer) rubber (such as, without limitation, EPDM and/or NBR) that include silver-based compounds to provide highly desirable long-term antimicrobial characteristics within the cured rubber articles, at least a portion of which exhibits a color other than black, are provided. Such articles are in either solid or blown (foam or sponge) state (or combinations of both in multilayered forms, either all colored or individual layers colored) that can be utilized in a variety of different applications. As silver-based compounds are deleteriously affected by utilization of standard curing agents and curing accelerators, such as sulfur-based compounds and/or systems, the ability to provide such an effective antimicrobial vulcanized rubber article is rather difficult. However, this invention encompasses the presence of different non-sulfur-based curing systems and agents, such as peroxides, as one example, that permit vulcanization and do not irreversibly bind silver ions thereto, thereby resulting in long-term antimicrobial performance of the ultimate rubber article itself. The rubber articles must also comprise fillers and may also include plasticizers to provide desired characteristics of dimensional stability, stiffness, flexural modulus, tensile strength, abrasion resistance, elongation, and the like, for the ultimate rubber article, while simultaneously and surprisingly both enhancing the control of antimicrobial efficacy of the rubber article and not deleteriously binding to the available silver to permit coloring of the target rubber as well.
    • 64. 发明授权
    • Procedures and apparatus for turning-on and turning-off elements within a field emission display device
    • 场致发射显示装置内的接通和关断元件的程序和装置
    • US06459209B1
    • 2002-10-01
    • US09767329
    • 2001-01-22
    • Donald J. EllowayDavid L. MorrisWilliam J. ScannellChristopher J. Spindt
    • Donald J. EllowayDavid L. MorrisWilliam J. ScannellChristopher J. Spindt
    • G09G310
    • G09G3/22G09G2310/06G09G2310/066G09G2330/02H01J9/39H01J9/44H01J31/127H01J2209/0223
    • A method of removing contaminant particles in newly fabricated field emission displays. According to one embodiment of the present invention, contaminant particles are removed by a conditioning process which includes the steps of: a) driving a anode of a field emission display (FED) to a predetermined voltage; b) slowly increasing an emission current of the FED after the anode has reached the predetermined voltage; and c) providing an ion-trapping device for catching the ions and particles knocked off, or otherwise released, by emitted electrons. In this embodiment, by driving the anode to the predetermined voltage and by slowly increasing the emission current of the FED, contaminant particles are effectively removed without damaging the FED. The present invention also provides a method of operating FEDs to prevent gate-to-emitter current during turn-on and turn-off. In this embodiment, the method comprises the steps of: a) enabling the anode display screen; and, b) enabling the electron-emitters after the anode display screen is enabled. In this embodiment, by allowing sufficient time for the anode display screen to reach a predetermined voltage before the emitter is enabled, the emitted electrons will be attracted to the anode.
    • 一种在新制造的场致发射显示器中去除污染物颗粒的方法。 根据本发明的一个实施例,污染物颗粒通过调节过程去除,包括以下步骤:a)将场致发射显示器(FED)的阳极驱动到预定电压; b)在阳极达到预定电压后缓慢增加FED的发射电流; 以及c)提供离子捕获装置,用于捕获被发射的电子撞击或以其它方式释放的离子和颗粒。 在本实施例中,通过将阳极驱动到预定电压并且通过缓慢增加FED的发射电流,有效地去除污染物颗粒而不损坏FED。 本发明还提供了一种在开启和关断期间操作FED以防止栅极 - 发射极电流的方法。 在该实施例中,该方法包括以下步骤:a)启用阳极显示屏; 并且b)在使能阳极显示屏幕之后启用电子发射器。 在本实施例中,通过在发射极使能之前允许阳极显示屏足够的时间达到预定电压,发射的电子将被吸引到阳极。
    • 69. 发明授权
    • Fad-labeled specific binding assay monitored with apoglutathione
reductase or apolipoamide dehydrogenase
    • 用谷抑肽酶还原酶或载脂蛋白脱氢酶监测Fad标记的特异性结合分析
    • US4318983A
    • 1982-03-09
    • US203525
    • 1980-11-03
    • William E. HornbyDavid L. Morris
    • William E. HornbyDavid L. Morris
    • C12N9/96G01N33/535G01N33/542G01N33/78G01N33/54
    • G01N33/78C12N9/96G01N33/535G01N33/542Y10S435/81Y10S435/96Y10S435/975
    • A specific binding assay for determining a ligand in a liquid medium employing an organic prosthetic group residue, such as a residue of flavin adenine dinucleotide, flavin mononucleotide, or heme, as a label component in the labeled conjugate. Preferably, the label component is the prosthetic group residue alone or is a holoenzyme residue comprising such prosthetic group residue combined with an apoenzyme in the form of a holoenzyme complex. In the former case, the label component preferably is monitored in the assay by adding an apoenzyme after the binding reaction has been initiated and measuring the resultant holoenzyme activity. In the latter case, the label component is monitored simply by measuring holoenzyme activity. The assay method may follow conventional homogeneous and heterogeneous schemes. Preferred apoenzymes for use in the assay are apoglucose oxidase and apoperoxidase. The assay offers the advantages of colorimetric read-out and of being readily adaptable to automated techniques. Also disclosed are prosthetic group-labeled and enzyme-labeled conjugates for use in the assay, as well as a method for preparing the latter conjugates.
    • 使用有机修饰基团残基(例如黄素腺嘌呤二核苷酸残基,黄素单核苷酸或血红素)作为标记缀合物中的标记成分来测定液体培养基中配体的特异性结合测定。 优选地,标记组分是单独的修饰基团残基,或者是包含与全酶复合物形式的脱辅基酶组合的这种假基团残基的全酶残基。 在前一种情况下,优选在测定中通过在结合反应开始后加入脱辅基酶并测量所得的全酶活性来监测标记组分。 在后一种情况下,通过测量全酶活性来简单地监测标签组分。 测定方法可以遵循常规的均相和异构方案。 用于测定的优选的脱辅基酶是糖苷氧化酶和过氧化物酶。 该测定提供比色读出的优点并且易于适应于自动化技术。 还公开了用于测定中的假体基团标记和酶标记的缀合物,以及制备后缀合物的方法。
    • 70. 发明授权
    • Apoglucose oxidase preparation
    • 葡萄糖氧化酶制剂
    • US4268631A
    • 1981-05-19
    • US45191
    • 1979-06-04
    • Paul B. EllisDavid L. Morris
    • Paul B. EllisDavid L. Morris
    • C12Q1/26C12N9/04G01N33/542
    • C12N9/0006G01N33/542Y10S435/815
    • An apoglucose oxidase preparation having a residual glucose oxidase activity of less than 0.05%, and preferably less than 0.005%. The preparation is obtained by incubation of glucose oxidase in aqueous solution at a pH of less than about 2 and in the presence of about 20 to about 40, preferably about 30, percent by volume glycerol, and separating resulting dissociated prosthetic group, flavin adenine dinucleotide, from apoglucose oxidase by column chromatography, preferably on cross-linked dextran gel. The purified apoglucose oxidase is useful as a reagent in specific binding assays employing flavin adenine dinucleotide as a label.
    • 具有小于0.05%,优选小于0.005%的残留葡萄糖氧化酶活性的糖苷氧化酶制剂。 通过将葡萄糖氧化酶在小于约2的pH和约20至约40,优选约30体积%甘油的存在下在水溶液中温育获得制备,并分离所得的解离的假体基团,黄素腺嘌呤二核苷酸 ,通过柱色谱从糖葡萄糖氧化酶,优选在交联的葡聚糖凝胶上。 在使用黄素腺嘌呤二核苷酸作为标记的特异性结合测定中,纯化的糖苷氧化酶可用作试剂。