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51. 发明申请

US20150119722A1 IMAGE PROCESSING APPARATUS, MICROSCOPE SYSTEM, ENDOSCOPE SYSTEM, AND IMAGE PROCESSING METHOD 有权
标题翻译：图像处理装置，显微镜系统，内窥镜系统和图像处理方法
公开(公告)号：US20150119722A1
公开(公告)日：2015-04-30
申请号：US14565960
申请日：2014-12-10
申请人： OLYMPUS CORPORATION
发明人： Yoshioki Kaneko
IPC分类号： A61B5/00 , G01N21/64 , G02B21/16 , A61B1/06
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/043 , A61B1/0661 , A61B5/415 , A61B5/4227 , G01N21/6456 , G01N21/6458 , G01N21/6486 , G01N2021/6417 , G01N2021/6484 , G01N2201/0826 , G02B21/16 , G02B21/365 , G02B2207/113 , G06T7/0012 , G06T2207/10068 , G06T2207/30024
摘要： An image processing apparatus includes: an image acquiring unit configured to acquire image information representing an image acquired by irradiating a gland duct with excitation light and observing fluorescence generated in the gland duct; a fluorescence intensity computation unit configured to compute a value corresponding to intensity of the fluorescence as fluorescence intensity based on the image information; and an image determination unit configured to determine whether or not an endocrine cell exists in the gland duct based on the fluorescence intensity computed by the fluorescence intensity computation unit, and to determine abnormality of the gland duct based on a determination result of the endocrine cell.
摘要翻译：一种图像处理装置，包括：图像获取单元，被配置为获取表示通过用激发光照射腺体管获得的图像的图像信息，并观察在腺体管中产生的荧光; 荧光强度计算单元，被配置为基于所述图像信息计算与所述荧光强度对应的值作为荧光强度; 以及图像判定单元，其基于由所述荧光强度计算单元计算的荧光强度来判定所述腺体管内是否存在内分泌细胞，并根据所述内分泌细胞的判定结果来确定所述腺体管的异常。

52. 发明申请

US20150109432A1 Scanner With Increased Dynamic Range 有权
标题翻译：扫描仪增加动态范围
公开(公告)号：US20150109432A1
公开(公告)日：2015-04-23
申请号：US14382277
申请日：2013-03-04
申请人： HURON TECHNOLOGIES INTERNATIONAL INC.
发明人： Arthur Edward Dixon , Savvas Damaskinos
IPC分类号： G02B21/00 , G02B21/36
CPC分类号： G02B21/008 , G01N21/6456 , G01N21/6458 , G01N2021/6417 , G02B21/0076 , G02B21/367
摘要： An instrument and method for scanning all or part of a large specimen mounted on a specimen holder takes a plurality of measurements of each pixel in the whole or part of the specimen being scanned at a plurality of exposure values. A computer controls the movement of the specimen holder during scanning and again of the detector to produce a digitized image of all or part of the specimen with larger dynamic range than the dynamic range of the detection system. In a further embodiment, the instrument can scan two successive, identical strips at a different exposure values and combine the images from the two scans into one digitized image having a larger dynamic range than the dynamic range of the detection system.
摘要翻译：用于扫描安装在样本保持器上的大样本的全部或部分的仪器和方法以多个曝光值对被扫描的全部或部分待检体中的每个像素进行多次测量。计算机在扫描期间控制样品架的运动，并再次检测检测器，以产生具有比检测系统的动态范围更大的动态范围的全部或部分样品的数字化图像。在另一个实施例中，仪器可以以不同的曝光值扫描两个连续的相同的条，并将来自两个扫描的图像组合成具有比检测系统的动态范围更大的动态范围的一个数字化图像。

53. 发明申请

US20150104860A1 Smartphone Biosensor 审中-公开
标题翻译：智能手机生物传感器
公开(公告)号：US20150104860A1
公开(公告)日：2015-04-16
申请号：US14579804
申请日：2014-12-22
申请人： The Board of Trustees of the University of Illinois
发明人： Brian T. Cunningham
IPC分类号： H04M1/725 , G01N21/25 , G01N21/64
CPC分类号： H04M1/72527 , G01J3/0202 , G01J3/0264 , G01J3/0272 , G01J3/28 , G01J3/44 , G01J3/4406 , G01N21/25 , G01N21/31 , G01N21/553 , G01N21/63 , G01N21/6428 , G01N21/6445 , G01N21/6486 , G01N21/658 , G01N21/7746 , G01N2021/6417 , G01N2201/0612 , G01N2201/062
摘要： A mobile computing device that includes an image sensor may be used to detect the result of a biomolecular assay. The biomolecular assay may be performed in an optical assay medium that provides an optical output in response to light from a light source, with the optical output indicating result. A wavelength-dispersive element may be used to disperse the optical output into spatially-separated wavelength components. The mobile computing device may be positioned relative to the wavelength-dispersive element such that different wavelength components are received at different locations on the image sensor. With the mobile computing device positioned in this way, the image sensor may be used to obtain one or more images that include the separated wavelength components of the optical output. A wavelength spectrum of the optical output may be determined from the one or more images, and the result may be determined from the wavelength spectrum.
摘要翻译：可以使用包括图像传感器的移动计算设备来检测生物分子测定的结果。生物分子测定可以在光学测定介质中进行，光学测定介质响应于来自光源的光而提供光学输出，光学输出指示结果。波长分散元件可以用于将光输出分散到空间分离的波长分量中。移动计算设备可以相对于波长分散元件定位，使得在图像传感器上的不同位置处接收不同的波长分量。利用以这种方式定位的移动计算设备，可以使用图像传感器来获得包括光输出的分离的波长分量的一个或多个图像。可以从一个或多个图像确定光学输出的波长谱，并且可以根据波长谱确定结果。

54. 发明授权

US08878145B1 Apparatus and method for fluorescence spectral and color measurements of diamonds, gemstones and the like 有权
标题翻译：用于钻石，宝石等的荧光光谱和颜色测量的装置和方法
公开(公告)号：US08878145B1
公开(公告)日：2014-11-04
申请号：US13560202
申请日：2012-07-27
申请人： Yan Liu
发明人： Yan Liu
IPC分类号： G01N21/64 , F21K2/00
CPC分类号： G01N21/87 , G01N21/255 , G01N2021/6417
摘要： An apparatus and method for fluorescence spectral and color measurements of diamonds, gemstones and the like. The apparatus comprises a spectrometer, and computer and a dual integrating sphere measurement arrangement comprising a measurement integrating sphere, a sample integrating sphere, a sample platform, a lens system, a baffle, an ultraviolet radiation source on the top of the sample integrating sphere, and another light source attached to the measurement integrating sphere. The sample on the sample platform is radiated by the ultraviolet radiation source on the top of the measurement integrating sphere. The sample emits fluorescent light into the measurement integrating sphere, and the fluorescent light is received by the lens system. The spectrometer separates the fluorescent light into spectral signals, and the computer calculates the fluorescence spectrum and colorimetric data.
摘要翻译：用于钻石，宝石等的荧光光谱和颜色测量的装置和方法。该装置包括光谱仪，计算机和双积分球测量装置，包括测量积分球，样品积分球，样品平台，透镜系统，挡板，样品积分球顶部的紫外线辐射源，另一个光源附在测量积分球上。样品平台上的样品由测量积分球顶部的紫外线辐射源辐射。样品将荧光发射到测量积分球中，并且荧光被透镜系统接收。光谱仪将荧光灯分为光谱信号，计算机计算荧光光谱和比色数据。

55. 发明申请

US20140242717A1 METHOD AND APPARATUS FOR OPTICAL DETECTION OF BIO-CONTAMINANTS 有权
标题翻译：用于光敏检测生物污染物的方法和装置
公开(公告)号：US20140242717A1
公开(公告)日：2014-08-28
申请号：US13777053
申请日：2013-02-26
申请人： INSTITUT NATIONAL D'OPTIQUE/NATIONAL OPTICS INSTITUTE , STERIS INC.
发明人： Daniel Rochette , Pascal Gallant , Ozge Mermut , Francois Baribeau , Isabelle Noiseux , Isabelle Gosselin
IPC分类号： G01N21/94
CPC分类号： G01N21/6428 , A61L2/28 , A61L2202/24 , G01N21/6486 , G01N21/94 , G01N2021/6417 , G01N2021/6439 , G01N2201/06113 , G01N2201/068 , G01N2201/0697 , G01N2201/10 , G01N2201/105
摘要： A method and apparatus for optical detection of residual soil on articles (such as medical instruments and equipment), after completion of a washing or a rinsing operation by a washer. A soil detection system provides an indication of soil on the articles by detecting luminescent radiation emanating from the soil in the presence of ambient light.
摘要翻译：在清洗完成洗涤或冲洗操作之后，用于光学检测物品（例如医疗仪器和设备）上残留土壤的方法和装置。土壤检测系统通过在环境光的存在下检测从土壤发出的发光辐射来提供物品上的土壤的指示。

56. 发明授权

US08781560B2 Method and apparatus for rapid detection and diagnosis of tissue abnormalities 有权
标题翻译：快速检测和诊断组织异常的方法和装置
公开(公告)号：US08781560B2
公开(公告)日：2014-07-15
申请号：US13228717
申请日：2011-09-09
申请人： Shabbir Bakir Bambot , Mark Faupel , Jonathan David Mongin
发明人： Shabbir Bakir Bambot , Mark Faupel , Jonathan David Mongin
IPC分类号： A61B5/00
CPC分类号： A61B5/4331 , A61B5/0059 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/0077 , G01J3/02 , G01J3/0208 , G01J3/0218 , G01J3/0229 , G01J3/0232 , G01J3/0262 , G01J3/0264 , G01J3/027 , G01J3/0272 , G01J3/0283 , G01J3/0291 , G01J3/10 , G01J3/28 , G01J3/4406 , G01J2003/1213 , G01J2003/2866 , G01N21/274 , G01N21/31 , G01N21/474 , G01N21/645 , G01N2021/6417 , G01N2021/6423 , G01N2021/6484 , G01N2201/0221
摘要： A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics and correlate same to photographic images. Further, the system and method accomplish this measurement rapidly by increasing the light throughput by integrating optics into a hand held unit and avoiding the need for a coherent fiber optic bundle being used. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.
摘要翻译：提供了一种方法和装置，用于询问，接收和分析至少一种荧光激发波长的全发射光谱，以及至少一次反射测量以确定组织特征并将其与摄影图像相关联。此外，该系统和方法通过将光学器件集成到手持式单元中并且避免对使用的相干光纤束的需要而增加光通量而快速地完成该测量。该方法包括用光能照射目标组织的第一部分，形成目标组织的第一图像，用光能照射目标组织的第二部分，对目标反射和/或发射的光能进行光谱测量基于光谱测量的结果确定目标组织的第二部分的光能量的组织，以及确定靶组织的组织特征。

57. 发明申请

US20140159860A1 Gas Activated Changes to Light Absorption and Emission Characteristics for Security Articles 有权
标题翻译：气体对安全物品的光吸收和排放特性的改变
公开(公告)号：US20140159860A1
公开(公告)日：2014-06-12
申请号：US14179833
申请日：2014-02-13
申请人： Nabil Lawandy
发明人： Nabil Lawandy
IPC分类号： G06F21/00
CPC分类号： B42D25/36 , B42D25/29 , G01N1/22 , G01N21/64 , G01N21/6408 , G01N21/643 , G01N21/783 , G01N2021/1795 , G01N2021/3137 , G01N2021/6417 , G01N2021/6419 , G01N2021/6439 , G06F21/00 , G06K7/10544 , G07D7/1205
摘要： Disclosed are security articles and methods and systems for authenticating security articles using a plurality of stimuli. According to one embodiment, an illustrative security feature includes an encoded feature wherein differential activation of phosphorescent or fluorescent materials creates a machine readable code through the simultaneous presence of a source of electromagnetic radiation and a specific gas environment. A detector detects a differential spectral emission across the security feature that results from the change in gas environment. The spectral emission may be compared to an expected emissive signature to determine authenticity of the security article.
摘要翻译：公开了用于使用多个刺激来认证安全物品的安全物品和方法和系统。根据一个实施例，说明性安全特征包括编码特征，其中磷光或荧光材料的差分激活通过同时存在电磁辐射源和特定气体环境而产生机器可读代码。检测器检测由气体环境变化导致的安全特征的差分光谱发射。可以将光谱发射与期望的发射签名进行比较以确定安全性文章的真实性。

58. 发明授权

US08735166B2 Polyanthrylene materials and methods for their preparation and use 有权
标题翻译：聚亚乙烯材料及其制备和使用方法
公开(公告)号：US08735166B2
公开(公告)日：2014-05-27
申请号：US13505059
申请日：2011-04-07
申请人： Mei-rong Huang , Shao-jun Huang , Jiang-Ying Li , Xin-gui Li
发明人： Mei-rong Huang , Shao-jun Huang , Jiang-Ying Li , Xin-gui Li
IPC分类号： G01N21/64 , B01J19/08 , C08G61/10
CPC分类号： G01N33/20 , C08G61/10 , C08G2261/314 , C08G2261/43 , C08L65/00 , C09K11/06 , C09K2211/1416 , G01N21/643 , G01N2021/6417 , Y10T436/21 , Y10T436/212
摘要： Compositions containing polyanthrylene and methods of making these compositions are disclosed herein. The polyanthrylene composition can, for example, be used for detection of iron in a sample.
摘要翻译：本文公开含有聚亚芳基的组合物和制备这些组合物的方法。聚亚苯基组合物可以例如用于检测样品中的铁。

59. 发明申请

US20140117255A1 SURFACE PLASMON-FIELD ENHANCED FLUORESCENCE SPECTROSCOPIC MEASUREMENT METHOD AND SURFACE PLASMON-FIELD ENHANCED FLUORESCENCE SPECTROSCOPIC MEASUREMENT DEVICE 有权
标题翻译：表面等离子体增强荧光光谱测量方法和表面等离子体增强荧光光谱测量装置
公开(公告)号：US20140117255A1
公开(公告)日：2014-05-01
申请号：US14126752
申请日：2012-05-31
申请人： Naoki Hikage , Masataka Matsuo , Takatoshi Kaya
发明人： Naoki Hikage , Masataka Matsuo , Takatoshi Kaya
IPC分类号： G01N21/64
CPC分类号： G01N21/64 , B01L3/502715 , B01L2300/0654 , B01L2300/0816 , B01L2300/168 , G01N21/648 , G01N33/54373 , G01N33/582 , G01N2021/6417 , G01N2021/6439 , G01N2021/6482
摘要： To provide a surface plasmon-field enhanced fluorescence spectroscopic measurement method and a surface plasmon-field enhanced fluorescence spectroscopic measurement device which are capable of accurately measuring a fluorescent signal regardless of the type of a light detection means even when the concentration of an analyte is high by adjusting the dynamic range of the SPFS device. A surface plasmon-field enhanced fluorescence stereoscopic measurement method wherein an analyte labeled with a fluorescent substance is excited by surface plasmon light generated by applying excitation light to a metallic thin film, and generated fluorescence is received by a light detection means to thereby detect the analyte. The dynamic range is expanded by adjusting the amount of the fluorescence received by the light detection means.
摘要翻译：提供表面等离子体场增强荧光光谱测量方法和表面等离子体激元增强荧光光谱测量装置，即使当分析物的浓度高时，也能够精确地测量荧光信号而不管光检测装置的类型通过调整SPFS设备的动态范围。一种表面等离子体场增强荧光立体测定方法，其中用荧光物质标记的分析物通过将激发光施加到金属薄膜而产生的表面等离子体激元激发，并且由光检测装置接收产生的荧光，从而检测分析物。通过调节由光检测装置接收的荧光的量来扩大动态范围。

60. 发明申请

US20140084153A1 Nanoparticulate Assisted Nanoscale Molecular Imaging by Mass Spectrometery 有权
标题翻译：纳米粒子辅助纳米尺度分子成像质谱
公开(公告)号：US20140084153A1
公开(公告)日：2014-03-27
申请号：US14092732
申请日：2013-11-27
申请人： Ionwerks, Inc.
发明人： J. Albert Schultz , Thomas F. Egan , Ernest K. Lewis , Steven Ulrich , Kelley L. Waters
IPC分类号： G01N21/64 , H01J49/26 , H01J49/40
CPC分类号： H01J49/10 , G01N21/64 , G01N21/6458 , G01N21/65 , G01N21/658 , G01N23/2258 , G01N2021/6417 , H01J49/0004 , H01J49/0422 , H01J49/0463 , H01J49/142 , H01J49/164 , H01J49/26 , H01J49/40
摘要： Methods and devices for mass spectrometry are described, specifically the use of nanoparticulate implantation as a matrix for secondary ion and more generally secondary particles. A photon beam source or a nanoparticulate beam source can be used a desorption source or a primary ion/primary particle source.
摘要翻译：描述了用于质谱的方法和装置，具体地，使用纳米颗粒注入作为二次离子的基质，更一般地说是二次粒子。光子束源或纳米颗粒束源可用于解吸源或初级离子/一次粒子源。

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