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51. 发明授权

US09176038B2 Apparatus and method for processing biological material 有权
标题翻译：用于处理生物材料的装置和方法
公开(公告)号：US09176038B2
公开(公告)日：2015-11-03
申请号：US13611211
申请日：2012-09-12
申请人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
发明人： Kyungyoon Min , Thomas E. Dudar , James C. Laird
IPC分类号： B01L3/00 , B01D21/00 , B01D21/26 , C12M1/00 , G01N1/40 , G01N15/04 , G01N21/07 , B01L1/00 , G01N15/14 , G01N21/03 , G01N35/10 , A61M39/04 , A61M39/26
CPC分类号： G01N1/4077 , A61M39/045 , A61M39/26 , B01D21/26 , B01D21/262 , B01L1/00 , B01L3/502 , B01L3/5021 , B01L3/5027 , B01L3/50273 , B01L3/502738 , B01L3/502753 , B01L3/50825 , B01L3/5635 , B01L2200/025 , B01L2200/026 , B01L2200/027 , B01L2200/0621 , B01L2200/0647 , B01L2200/10 , B01L2300/044 , B01L2300/046 , B01L2300/049 , B01L2400/0409 , B01L2400/0478 , B01L2400/0481 , B01L2400/0633 , C12M47/02 , G01N1/40 , G01N15/042 , G01N21/03 , G01N21/07 , G01N33/491 , G01N2001/4083 , G01N2015/149 , G01N2035/00495 , G01N2035/1058
摘要： The application discloses an apparatus and method for processing biological material, including a suspension of cells.
摘要翻译：本申请公开了一种用于处理生物材料的装置和方法，包括细胞悬浮液。

52. 发明授权

US09162228B2 Interlocking cap and receptacle for automated processes 有权
标题翻译：用于自动化过程的联锁盖和插座
公开(公告)号：US09162228B2
公开(公告)日：2015-10-20
申请号：US14210042
申请日：2014-03-13
申请人： GEN-PROBE INCORPORATED
发明人： Byron J. Knight
IPC分类号： B01L3/00 , B65B69/00 , B65D39/00 , G01N35/02 , C12Q1/68
CPC分类号： B01L3/5085 , B01L3/502 , B01L3/5082 , B01L3/50825 , B01L3/50853 , B01L3/50855 , B01L3/523 , B01L3/527 , B01L2200/02 , B01L2200/025 , B01L2200/026 , B01L2200/0668 , B01L2200/0689 , B01L2200/141 , B01L2200/142 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/046 , B01L2300/047 , B01L2300/048 , B01L2300/0609 , B01L2300/0829 , B01L2300/0832 , B01L2300/0838 , B01L2300/0851 , B01L2300/0858 , B01L2300/12 , B01L2400/0406 , B65B69/00 , B65D1/0207 , B65D1/34 , B65D1/36 , B65D17/50 , B65D39/0017 , B65D39/0029 , B65D2539/003 , C12Q1/686 , G01N30/6091 , G01N35/0099 , G01N35/026 , G01N35/10 , G01N35/1002 , G01N35/1079 , G01N2035/00287 , Y10T436/11
摘要： System, apparatuses, and methods for performing automated reagent-based analysis are provided. Also provided are methods for automated attachment of a cap to a reaction receptacle, and automated removal of a cap from a capped reaction receptacle.
摘要翻译：提供了用于执行基于自动化试剂的分析的系统，装置和方法。还提供了用于将盖自动附接到反应容器的方法，以及从加盖的反应容器自动移除盖。

53. 发明申请

US20150290640A1 VESSEL 审中-公开
标题翻译：船只
公开(公告)号：US20150290640A1
公开(公告)日：2015-10-15
申请号：US14437558
申请日：2013-10-15
申请人： RPC FORMATEC GMBH
发明人： Sabine Goettke
IPC分类号： B01L3/00
CPC分类号： B01L3/50825 , A61B5/150015 , A61B5/150351 , B01L3/5021 , B01L2200/0689 , B01L2300/042 , B01L2300/045 , B65D41/086
摘要： A vessel, in particular for receiving small quantities of liquid, for example for receiving analysis samples, has a vessel body which has a small diameter relative to a vessel length. The vessel body has a longitudinal axis and an opening which can be closed by a screw cap. This vessel is advantageously easy to handle with respect to closing the vessel. The screw cap can be secured by plugging the screw cap in the direction of the longitudinal axis in order to close the opening using an adapter part to which the screw cap is screw-fastened; afterwards, however, the opening can only be released by unscrewing the screw cap.
摘要翻译：特别是用于接收少量液体的容器，例如用于接收分析样品的容器具有相对于容器长度具有小直径的容器主体。容器主体具有纵向轴线和可由螺旋盖封闭的开口。该容器在关闭容器方面有利地易于处理。可以通过沿纵向轴线的方向堵塞螺丝帽来固定螺丝帽，以便使用螺钉固定螺丝帽的适配器部件来关闭开口; 然而，然后，只能通过拧下螺丝帽来释放开口。

54. 发明授权

US09140715B2 System and method for controlling thermal cycler modules 有权
标题翻译：用于控制热循环仪模块的系统和方法
公开(公告)号：US09140715B2
公开(公告)日：2015-09-22
申请号：US13747952
申请日：2013-01-23
申请人： Beckman Coulter, Inc.
发明人： Brian D. Wilson , Matthew S. Davis , Alan N. Johnson , Garrick A. Maurer
IPC分类号： C12P19/34 , G01N35/04 , G01N35/10 , G01N35/00 , B01L3/00 , B01L7/00 , C12Q3/00 , G05B13/02 , G01F23/24 , G01F23/26 , G06F19/10 , C12M1/34 , C12Q1/68 , G01N1/38 , G01N1/31 , B01L3/02
CPC分类号： G01N35/04 , B01L3/021 , B01L3/0275 , B01L3/50825 , B01L3/5085 , B01L3/50851 , B01L3/52 , B01L3/545 , B01L7/52 , B01L2200/025 , B01L2200/0642 , B01L2200/0668 , B01L2200/12 , B01L2200/147 , B01L2300/021 , B01L2300/022 , B01L2300/024 , B01L2300/042 , B01L2300/044 , B01L2300/045 , B01L2300/046 , B01L2300/0654 , B01L2300/0851 , B01L2300/123 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2400/043 , C12M41/12 , C12P19/34 , C12Q1/68 , C12Q1/686 , C12Q3/00 , G01F23/24 , G01F23/26 , G01N1/31 , G01N1/38 , G01N35/00732 , G01N35/0092 , G01N35/0098 , G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N35/1081 , G01N2035/00435 , G01N2035/00752 , G01N2035/00851 , G01N2035/0413 , G01N2035/0415 , G01N2035/0436 , G01N2035/0465 , G01N2035/0475 , G01N2035/1013 , G01N2035/1025 , G01N2035/1048 , G01N2035/1051 , G01N2035/1076 , G05B13/02 , G05B13/0205 , G06F19/10 , Y10T436/113332
摘要： Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.
摘要翻译：公开了用于处理和分析样品的系统和方法。该系统可以使用可在不同处理位置处理的测定盒来处理样品，例如生物流体。在某些情况下，该系统可用于PCR处理。不同的处理位置可以包括可以准备样品的准备位置和可以分析样品的分析位置。为了帮助准备样品，系统还可以包括可以包括加工车道的多个处理站。在样品分析期间，在某些情况下，热循环仪模块和适当的光学检测系统可用于检测样品中某些核酸序列的存在或不存在。该系统可用于准确快速地处理样品。

55. 发明申请

US20150253201A1 SAMPLE CONTAINER WITH SENSOR RECEPTABLE AND METHODS OF USE 审中-公开
标题翻译：具有传感器可接受的样品容器和使用方法
公开(公告)号：US20150253201A1
公开(公告)日：2015-09-10
申请号：US14719798
申请日：2015-05-22
申请人： HeatFlow Technologies Inc.
发明人： Warren L. DINGES
IPC分类号： G01K1/08 , G01K13/00
CPC分类号： G01K1/08 , B01L3/50825 , B01L7/52 , B01L2200/141 , B01L2200/147 , B01L2300/042 , B01L2300/047 , B01L2300/0851 , B01L2300/12 , G01K13/00
摘要： Devices and methods are described herein that are configured for use in laboratory testing, such as, for example, during a procedure including the monitoring and detection of chemical reactions. For example, the systems and devices described herein can be used during a procedure to monitor and detect polymerase chain reactions (PCR). In some embodiments, a sample container includes a container body that defines an interior volume and has an open end in fluid communication with the interior volume. A cap is sealingly engageable with the open end of the container body. The cap defines a receptacle that is configured to extend within a portion of the interior volume of the container body when the cap is sealingly engaged thereto. The receptacle can receive therein a sensor, such as, a temperature sensor that can monitor the temperature of a sample material disposed within the container body.
摘要翻译：本文描述了被配置用于实验室测试的装置和方法，例如在包括监测和检测化学反应的过程中。例如，本文所述的系统和装置可以在监测和检测聚合酶链反应（PCR）的过程中使用。在一些实施例中，样品容器包括限定内部容积并且具有与内部容积流体连通的开口端的容器主体。盖子可与容器主体的开口端密封地接合。所述盖限定了当所述盖与所述盖密封地接合到所述容器主体的内部容积的一部分内时延伸的容器。容器可以在其中容纳传感器，例如可以监测设置在容器主体内的样品材料的温度的温度传感器。

56. 发明授权

US09128017B2 Device, systems and methods for analyzing a target analyte 有权
标题翻译：用于分析目标分析物的装置，系统和方法
公开(公告)号：US09128017B2
公开(公告)日：2015-09-08
申请号：US14213751
申请日：2014-03-14
申请人： RareCyte, Inc.
发明人： Daniel Campton , Jackie Lynn Stilwell , Arturo Ramirez , Jennifer Chow
IPC分类号： B01L99/00 , G01N1/40 , G01N1/28 , G01N33/49 , B01L3/00
CPC分类号： G01N1/4077 , B01L3/50215 , B01L3/50825 , B01L2200/0668 , B01L2300/042 , B01L2300/046 , B01L2300/047 , B01L2400/043 , G01N1/28 , G01N33/487 , G01N33/49 , G01N2001/4083
摘要： This disclosure is directed to a cap for obtaining a target analyte from a suspension. The cap introduces a magnetic field or a magnetic gradient to the tube to draw the target analyte bound to a particle to the cap. In one aspect, a cap includes a magnetic insert and a receiving piece. The magnetic insert includes a stopper and a magnet extending from the stopper; and, the receiving piece, which is configured to hold the magnetic insert, includes a receiving stopper and a sheath. The sheath may include imaging slides on opposite sides of the sheath. In another aspect, the cap may include a stopper and an embedded magnet. The cap may include an analysis piece on a bottom end of the stopper. In yet another aspect, the cap may include a fluid compartment and a filter at a bottom end of the stopper.
摘要翻译：本公开涉及从悬浮液获得目标分析物的盖。帽向管引入磁场或磁梯度，以将与颗粒结合的靶分析物吸引到帽上。一方面，盖包括磁性插入件和接收件。磁性插入件包括止动件和从止动件延伸的磁体; 并且构造成保持磁性插入件的接收片包括接收塞子和护套。护套可以包括在护套的相对侧上的成像载片。在另一方面，盖可以包括止动器和嵌入式磁体。帽可以包括在止动器的底端上的分析片。在另一方面，盖子可以包括在塞子的底端处的流体隔室和过滤器。

57. 发明申请

US20150231632A1 SPIN ELUTE TUBE 审中-公开
标题翻译：旋压管
公开(公告)号：US20150231632A1
公开(公告)日：2015-08-20
申请号：US14428252
申请日：2013-09-11
申请人： Robert SHARTLE , Behrad VAHIDI , William M. STRAUSS
发明人： Robert Shartle , Behrad Vahidi , William M. Strauss
IPC分类号： B01L3/00 , B01D21/26
CPC分类号： B01L3/50825 , B01D21/262 , B01L3/5021 , B01L3/5027 , B01L7/52 , B01L2300/04 , B01L2300/042 , B01L2400/0409
摘要： Provided are devices for recovery of cells from a microfluidic device.
摘要翻译：提供了用于从微流体装置回收细胞的装置。

58. 发明授权

US09101936B2 Sealed oxygen reference fluid containing bag 有权
标题翻译：密封氧气参考流体袋
公开(公告)号：US09101936B2
公开(公告)日：2015-08-11
申请号：US12081996
申请日：2008-04-24
申请人： Ib Marcher , Henrik Siiger , Allan Spork
发明人： Ib Marcher , Henrik Siiger , Allan Spork
IPC分类号： B65D33/24 , B01L3/00 , B65D41/00 , B65D30/00 , B65D51/00 , B65D75/58 , G01N33/96 , B65D33/16
CPC分类号： B01L3/505 , B01L3/50 , B01L3/50825 , B01L2200/025 , B01L2200/026 , B01L2200/0689 , B01L2300/04 , B01L2300/041 , B01L2300/044 , B01L2300/0848 , B65D51/002 , B65D75/58 , G01N33/96 , G01N2496/70
摘要： The invention relates to a sealed oxygen reference fluid containing bag adapted for being pierced by an access probe for withdrawal of the oxygen reference fluid and including an access system comprising: a sealing element provided outside the bag and preventing any leakage between the bag and the access probe when the access probe has penetrated the bag, and a longitudinal support element provided inside the bag extending essentially parallel to an edge of the bag and being adapted to support the bag when the bag is penetrated by the access probe.
摘要翻译：本发明涉及一种密封的氧气参考流体容纳袋，其适用于由用于取出氧气参考流体的进入探针刺穿并包括一个进入系统，该通道系统包括：设置在该袋外部的密封元件，并防止该袋与该通道之间的任何泄漏当接近探针已经穿过袋子时探针，以及设置在袋内的纵向支撑元件，其基本上平行于袋的边缘延伸，并且当袋子被进入探针穿透时适于支撑袋子。

59. 发明授权

US09097672B2 Method and system for detecting biological molecules in samples 有权
标题翻译：检测样品中生物分子的方法和系统
公开(公告)号：US09097672B2
公开(公告)日：2015-08-04
申请号：US13704719
申请日：2011-06-17
申请人： R. Stephen Brown , Eric Marcotte , Doug Wilton , Peter Gallant , David Dolphin , Lee Underwood
发明人： R. Stephen Brown , Eric Marcotte , Doug Wilton , Peter Gallant , David Dolphin , Lee Underwood
IPC分类号： G01N21/64 , G01N33/12 , G01N33/18 , B01L3/00
CPC分类号： G01N21/6486 , B01L3/50825 , G01N21/6428 , G01N21/6452 , G01N33/12 , G01N33/1826 , G01N2021/6417 , G01N2021/6482 , G01N2021/6484 , G01N2201/062
摘要： A system for detecting presence of an organism having an enzyme in a sample, comprising: a cartridge for containing the sample and a substrate such that the enzyme can react with the substrate to produce a biological molecule; a partitioning element mounted in a recess in a base of the cartridge, the partitioning element allowing partitioning of the biological molecule thereinto; a light source for irradiating the biological molecule partitioned into the partitioning element; and, a detector for detecting fluorescence of the biological molecule partitioned into the partitioning element, the detected fluorescence being indicative of presence of the organism in the sample; wherein the light source is in a raised cartridge mount of the system that mates with the recess in the base of the cartridge.
摘要翻译：一种用于检测样品中具有酶的生物体的存在的系统，包括：用于容纳样品和底物的筒，使得酶可以与底物反应以产生生物分子; 安装在所述盒的基部中的凹部中的分隔元件，所述分隔元件允许生物分子在其中分配; 用于照射被划分成分隔元件的生物分子的光源; 以及检测器，用于检测划分成分隔元件的生物分子的荧光，检测到的荧光指示样品中生物体的存在; 其中所述光源位于所述系统的凸起的盒安装件中，以与所述盒的所述底座中的凹部配合。

60. 发明授权

US09091672B2 Retaining device for a pipetting needle 有权
标题翻译：移液针固定装置
公开(公告)号：US09091672B2
公开(公告)日：2015-07-28
申请号：US14206603
申请日：2014-03-12
申请人： Siemens Healthcare Diagnostics Products GmbH
发明人： Hugo Wilmes
IPC分类号： G01N35/10 , B01L3/00
CPC分类号： G01N35/1079 , B01L3/50825
摘要： The invention relates to a retaining device (1) for a hollow needle (12) of a pipetting device in an automatic analysis apparatus. The retaining device (1) comprises a first retaining element (2), which can be secured releasably on a base plate that is movable in an automated manner, and a second retaining element (4), which is connected to the first retaining element (2), wherein at least one bearing bushing (14) is provided, which is fixed between the retaining elements (2, 4) and in which the hollow needle (12) is mounted.
摘要翻译：本发明涉及一种用于自动分析装置中的移液装置的中空针（12）的保持装置（1）。保持装置（1）包括第一保持元件（2），该第一保持元件可释放地固定在可自动移动的基板上;第二保持元件（4），其连接到第一保持元件其中至少一个轴承衬套（14）被固定在所述保持元件（2,4）之间并且所述中空针头（12）安装在所述轴承衬套中。

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