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51. 发明授权

US5800594A Column and processes for purifying solvent-containing gases 失效
标题翻译：用于净化含溶剂气体的柱和工艺
公开(公告)号：US5800594A
公开(公告)日：1998-09-01
申请号：US797184
申请日：1997-02-10
申请人： Werner Sievers , Gunter Muller
发明人： Werner Sievers , Gunter Muller
IPC分类号： B01D53/44 , B01D47/14 , B01D53/14 , B01D53/18
CPC分类号： B01D47/14 , B01D53/18
摘要： The invention relates to a fluidized-bed scrubber containing fluidizing bodies for purifying gases and to processes for its operation. The invention enables the fluidized-bed scrubber to be dimensioned, and the processes to be carried out, in such a manner that the number of fluidizing bodies is minimized and as much energy as possible is saved, without this decreasing the purifying efficiency.
摘要翻译：本发明涉及一种流化床洗涤器，其包含用于净化气体的流化体及其操作过程。本发明能够使流化床洗涤器的尺寸确定，并且以使得流化体的数量最小化并且尽可能减少能量的方式进行处理，而不会降低净化效率。

52. 发明授权

US4620585A Apparatus for the compaction of foundry mold material 失效
标题翻译：铸造模具材料压实装置
公开(公告)号：US4620585A
公开(公告)日：1986-11-04
申请号：US617920
申请日：1984-06-06
申请人： Gunter Muller , Norbert Damm , Gunter Kuppinger
发明人： Gunter Muller , Norbert Damm , Gunter Kuppinger
IPC分类号： B22C5/12 , B22C15/00 , B22C15/24
CPC分类号： B22C15/00
摘要： An apparatus for the compaction of foundry mold making material using gas under pressure, comprises a pressure vessel for the such gas, a mold flask, a filling frame, a pattern plate and a pattern thereon onto which the material is to be loosely heaped. The flask, frame and plate form a mold chamber under the pressure vessel and between them there a valve is placed, the valve having a movable valve member adapted to open up a flow cross section of the valve predominantly under the effect of gas under pressure in the pressure vessel. The valve member is guided within the pressure vessel, with the valve member being adapted to perform an opening motion, which at least mainly directed into the mold chamber.
摘要翻译：用于在压力下使用气体压实铸造模具制造材料的装置包括用于这种气体的压力容器，模具烧瓶，填充框架，图案板和其上要松散堆叠的材料的图案。烧瓶，框架和板在压力容器下形成模具室，并且在它们之间放置有阀，阀具有可移动的阀构件，该活动阀构件主要在压力下的气体的作用下打开阀的流动横截面压力容器。阀构件在压力容器内被引导，阀构件适于执行至少主要导向模具室的开启运动。

53. 发明授权

US4619307A Apparatus for compressing foundry moulding material by pressure gas 失效
标题翻译：压力气体压缩铸造成型材料的装置
公开(公告)号：US4619307A
公开(公告)日：1986-10-28
申请号：US767274
申请日：1985-08-02
申请人： Gunter Muller , Norbert Damm
发明人： Gunter Muller , Norbert Damm
IPC分类号： B22C15/23 , B22C15/00
CPC分类号： B22C15/00
摘要： In an apparatus for compressing foundry moulding material by pressure gas comprising a pressure vessel for the pressure gas forming an inlet pressure chamber, a moulding chamber positioned below it formed from moulding boxes with sand frames and a pattern plate with pattern on which the moulding material is loosely heaped up prior to compression and a large-area valve arranged between the pressure vessel and the moulding chamber, its closure member frees the valve opening in a few milliseconds, accompanied by the joint action of the pressure in the pressure vessel and thereby moves into the moulding chamber. The closure member is brought into the closed position by a pressure cylinder, whose piston is connected on the stroke side to a high pressure source and with its opposite side forms the movable termination of a gas-pressurized pressure reservoir, the high pressure side outflow being constructed in such a way that the pressure medium flows out at a speed of more than 10 m/s, accompanied by the simultaneous acceleration of the piston under the pressure in the pressure reservoir and the closure member into the open position.
摘要翻译： PCT No.PCT / EP84 / 00392 Sec。 371日期1985年8月2日 102（e）日期1985年8月2日PCT提交1984年12月7日PCT公布。第WO85 / 02568号公报日期：1985年6月20日。在通过压力气体压缩铸造模制材料的设备中，包括用于形成入口压力室的压力气体的压力容器，位于其下方的模制室由具有砂框架的模制箱和具有模制材料在压缩之前松散地堆积在其上并且大面积的阀布置在压力容器和模制室之间，其封闭构件在几毫秒内释放阀开口，伴随着压力的联合作用压力容器，从而移动到模制室中。关闭构件通过压力缸进入关闭位置，压力缸的活塞在行程侧连接到高压源，并且其相对侧形成气体加压压力储存器的可移动终端，高压侧流出为以使压力介质以大于10m / s的速度流出的方式构造，伴随着在压力贮存器和关闭构件的压力下活塞同时加速到打开位置。

54. 发明授权

US3987985A Device for sealing off fuselage gap of aircraft 失效
标题翻译：用于密封飞机的密封空间的装置
公开(公告)号：US3987985A
公开(公告)日：1976-10-26
申请号：US596620
申请日：1975-07-17
申请人： Gunter Muller
发明人： Gunter Muller
IPC分类号： B64C3/40 , B64C1/14
CPC分类号： B64C3/40
摘要： A device for sealing the fuselage gap in a variable geometry aircraft. The fuselage gap is designed to receive part of the movable wing on the aircraft. The seal is in contact with the upper and lower wing surfaces near the inboard trailing edge section so that the fuselage gap is effectively sealed during flight. The seal is constructed of an air bellows with a triangular-shaped cross section and a plurality of partition walls therein, each partition wall being filled with air passageways in order to allow equilization of air pressure within the bellows. The partition walls are connected to one of the outer sheath walls of the bellows through a hinge-like connection. The hinge consists of numerous loops with a hinge pin protruding through the loops to interlock the concerned outer wall of the bellows with the partition walls. In another embodiment, a one-piece, elastic wire is threaded through the loops of all partition walls consecutively. The partition walls may be connected to the outer bellows sheath also through a force-locking device.

55. 发明授权

US08921404B2 Azole derivatives in the form of lipase and phospholipase inhibitors 有权
标题翻译：脂肪酶和磷脂酶抑制剂形式的唑衍生物
公开(公告)号：US08921404B2
公开(公告)日：2014-12-30
申请号：US11873846
申请日：2007-10-17
申请人： Gerhard Zoller , Stefan Petry , Gunter Muller , Hubert Heuer , Norbert Tennagels
发明人： Gerhard Zoller , Stefan Petry , Gunter Muller , Hubert Heuer , Norbert Tennagels
IPC分类号： A61K31/4523 , A61K31/423 , A61K31/428 , C07D275/04 , C07D498/04 , C07D261/20 , C07D413/12 , C07D513/04
CPC分类号： C07D261/20 , C07D275/04 , C07D413/12 , C07D513/04
摘要： The invention relates to azole derivatives of the general formula I as defined in the present application as well as to their uses in treatment of conditions that would benefit from their inhibitory effect on hormone sensitive lipase, HSL, an allosteric enzyme in adipocytes which is inhibited by insulin and is responsible for the breakdown of fats in fat cells and thus for transferring fat constituents into the blood stream. Inhibition of this enzyme is therefore equivalent to an insulin-like effect of the compounds of the invention.
摘要翻译：本发明涉及本申请中定义的通式I的唑衍生物，以及它们在治疗受益于其对激素敏感性脂肪酶HSL（对脂肪细胞中受抑制的脂肪细胞中的变构酶）的抑制作用的条件的用途胰岛素，并且负责脂肪细胞中脂肪的分解，从而将脂肪成分转移到血液中。因此，该酶的抑制等同于本发明化合物的胰岛素样效应。

56. 发明授权

US08633156B2 Insulin derivatives having an extremely delayed time-action profile 有权
标题翻译：具有非常延迟的时间作用特征的胰岛素衍生物
公开(公告)号：US08633156B2
公开(公告)日：2014-01-21
申请号：US12820727
申请日：2010-06-22
申请人： Paul Habermann , Gerhard Seipke , Roland Kurrle , Gunter Muller , Mark Sommerfeld , Norbert Tennagels , Georg Tschank , Ulrich Werner
发明人： Paul Habermann , Gerhard Seipke , Roland Kurrle , Gunter Muller , Mark Sommerfeld , Norbert Tennagels , Georg Tschank , Ulrich Werner
IPC分类号： A61K38/28 , A61K38/26
CPC分类号： C07K14/62
摘要： The invention relates to novel insulin analogs having a basal time-action profile, which are characterized by the addition and/or substitution of negatively and positively charged amino acid residues and by an amidation of the C-terminal carboxy group of the B chain and histidine in position 8 of the insulin A chain. The invention also relates to the production and use thereof.
摘要翻译：本发明涉及具有基础时间作用特征的新型胰岛素类似物，其特征在于负和带正电荷的氨基酸残基的添加和/或取代以及B链和组氨酸的C端羧基的酰胺化在胰岛素A链的位置8。本发明还涉及其生产和使用。

57. 发明授权

US08148395B2 Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases 有权
标题翻译：偶氮吡啶-3-酮衍生物作为脂肪酶和磷脂酶的抑制剂
公开(公告)号：US08148395B2
公开(公告)日：2012-04-03
申请号：US12235047
申请日：2008-09-22
申请人： Gerhard Zoller , Stefan Petry , Gunter Muller , Norbert Tennagels
发明人： Gerhard Zoller , Stefan Petry , Gunter Muller , Norbert Tennagels
IPC分类号： A61K31/44 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号： C07D471/04
摘要： The present invention relates to azolopyridin-3-one derivatives of the general formula I with the meanings indicated in the description, their pharmaceutically usable salts and their use as medicinal substances.
摘要翻译：本发明涉及通式I的苯并吡喃-3-酮衍生物，其具有说明书中所述的含义，其药学上可用的盐及其作为药用物质的用途。

58. 发明授权

US08065331B2 Personalized website and database for a medical organization 有权
标题翻译：医疗机构的个性化网站和数据库
公开(公告)号：US08065331B2
公开(公告)日：2011-11-22
申请号：US12133893
申请日：2008-06-05
申请人： Gunter Muller , Claus Werner
发明人： Gunter Muller , Claus Werner
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06Q50/22 , G06F19/00 , G06Q10/10 , Y10S707/944
摘要： A system and method for managing the access of individuals to an information infrastructure is described. The metaphor for the user interface may be “myIntranet”, suggesting that the functions are similar to that of a browser of a client connected to the world-wide-web (WWW) through the Internet. The home page of “myIntranet” may be customized at a plurality of organizational levels within a medical facility, so as to provide rapid access to information that a person needs to perform a particular job responsibility. Each person may have a unique home page, or the home page may be customized, in part, by the user. Other portions of the home page may be customized by the department, the information technology organization, or other user with the appropriate permission. The configuration of the home page is associated with the individual user through a log-on procedure.
摘要翻译：描述了一种用于管理个人访问信息基础设施的系统和方法。用户界面的隐喻可能是“myIntranet”，表明这些功能类似于通过Internet连接到万维网（WWW）的客户端的浏览器。 “myIntranet”的主页可以在医疗设施内的多个组织级别进行定制，以便快速访问人需要执行特定工作职责的信息。每个人可以具有唯一的主页，或者主页可以部分地由用户定制。主页的其他部分可能由部门，信息技术组织或其他用户在适当的许可下进行定制。主页的配置通过登录过程与个人用户相关联。

59. 发明授权

US07754713B2 4-benzimidazol-2-ylpyridazin-3-one derivatives 失效
标题翻译： 4-苯并咪唑-2-基哒嗪-3-酮衍生物
公开(公告)号：US07754713B2
公开(公告)日：2010-07-13
申请号：US12251572
申请日：2008-10-15
申请人： Swen Hoelder , Karl Schoenafinger , David William Will , Hans Matter , Gunter Muller , Cecile Combeau , Christine Delaisi , Anke Steinmetz , Ingrid Sassoon
发明人： Swen Hoelder , Karl Schoenafinger , David William Will , Hans Matter , Gunter Muller , Cecile Combeau , Christine Delaisi , Anke Steinmetz , Ingrid Sassoon
IPC分类号： A61K31/501 , A61K31/5355 , A61P35/00 , C07D401/14 , C07D403/04 , C07D413/14
CPC分类号： C07D401/14 , C07D403/04 , C07D403/14 , C07D471/04
摘要： Disclosed are compounds of the general formula (I), where the definition of the substituents A, B, D, E, R1 and R2 are detailed in the description, and the physiologically tolerated salts thereof, a process for the preparation of these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase CDK2 (cyclin-dependent kinase 2).
摘要翻译：公开了通式（I）的化合物，其中取代基A，B，D，E，R 1和R 2的定义在说明书中详细描述，以及其生理上可耐受的盐，这些化合物的制备方法和它们用作药物。这些化合物是激酶抑制剂，特别是激酶CDK2（细胞周期蛋白依赖性激酶2）的抑制剂。

60. 发明授权

US07507734B2 Pyridazinone derivatives 失效
标题翻译：哒嗪酮衍生物
公开(公告)号：US07507734B2
公开(公告)日：2009-03-24
申请号：US11560620
申请日：2006-11-16
申请人： Swen Hoelder , Gunter Muller , Karl Schoenafinger , David William Will , Hans Matter , Martin Bossart , Cecile Combeau , Christine Delaisi , Ingrid Sassoon , Anke Steinmetz , Didier Benard
发明人： Swen Hoelder , Gunter Muller , Karl Schoenafinger , David William Will , Hans Matter , Martin Bossart , Cecile Combeau , Christine Delaisi , Ingrid Sassoon , Anke Steinmetz , Didier Benard
IPC分类号： A61K31/501 , C07D401/04 , C07D403/04 , C07D405/04 , C07D409/04 , C07D413/14 , C07D487/04 , A61K31/53 , A61K31/5355 , A61P35/00
CPC分类号： C07D403/04 , C07D401/14
摘要： Disclosed are compounds according to the general formula (I), where the definitions of the substituents X, R1 and R2 are detailed in the description, as well as their physiologically acceptable salts and solvate, methods for producing these compounds and their use as pharmaceuticals. These compounds are kinase inhibitors, in particular inhibitors of the kinase CDK2 (cyclin-dependent kinase 2).
摘要翻译：公开了根据通式（I）的化合物，其中取代基X，R 1和R 2的定义在说明书中详细描述，以及它们的生理上可接受的盐和溶剂合物，这些化合物的制备方法及其作为药物的用途。这些化合物是激酶抑制剂，特别是激酶CDK2（细胞周期蛋白依赖性激酶2）的抑制剂。

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