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    • 52. 发明申请
    • Methods of automatically generating dummy fill having reduced storage size
    • 自动生成减少存储大小的虚拟填充的方法
    • US20080121939A1
    • 2008-05-29
    • US11593892
    • 2006-11-06
    • Michael MurrayVan Nguyen
    • Michael MurrayVan Nguyen
    • H01L27/10G06F17/50
    • H01L22/20G03F1/36H01L2924/0002H01L2924/00
    • The disclosure relates generally to production of lithography masks such as used in mass production of monolithic integrated circuits (IC's). Layers of such IC's often need to be filled with dummy-fill. In accordance with the disclosure, dummy-objects are first generated by a conventional flat-fill technique and then they are automatically surrounded by outlines that are substantially wrinkle-free. The outlines are cleared of the original flat-fill and then used as areas that are to be automatically tiled by an auto-tiling program. Tiles are then re-filled with array definitions of regularly-spaced dummy-objects. The arrays consume less data storage space than do the original, individually-specified (flat-filled) dummy-objects. The array data is appended to layout data of functional objects in a layer of the integrated monolithic device (IC) to thereby generate a dummy-filled tapeout file. The dummy-filled tapeout file is subjected to pre-tapeout rules checking and then transmitted via a network to a mask house for production of a corresponding lithography mask. The lithography mask is used to mass produce corresponding integrated circuits.
    • 本公开通常涉及用于批量生产单片集成电路(IC)的光刻掩模的生产。 这种IC的层通常需要填充虚拟填充。 根据本公开,虚拟物体首先通过常规的平填技术生成,然后它们被基本上无皱纹的轮廓自动地包围。 轮廓线被清除原始的平面填充,然后被用作自动平铺程序自动平铺的区域。 然后使用规则间隔的虚拟对象的数组定义重新填充瓷砖。 与原始的,单独指定的(平坦填充的)虚拟对象相比,阵列消耗的数据存储空间较少。 将阵列数据附加到集成单片设备(IC)的层中的功能对象的布局数据,从而生成虚拟填充的流图文件。 虚拟填充的流图文件经受预先流图规则检查,然后经由网络传输到掩模室,以生产相应的光刻掩模。 光刻掩模用于批量生产相应的集成电路。
    • 54. 发明申请
    • CATHETER PRODUCT PACKAGE AND METHOD OF FORMING SAME
    • 导管产品包装及其形成方法
    • US20070289887A1
    • 2007-12-20
    • US11760545
    • 2007-06-08
    • Michael MurrayKai Jorgensen
    • Michael MurrayKai Jorgensen
    • B65D69/00A61B19/02B65D83/10
    • B65D51/00A61M25/002A61M25/0111
    • A catheter product package and method of forming same in which the package comprises a sheet material wrapped about the catheter product to form a package for the catheter product. The catheter product extends generally longitudinally within the package, and the sheet material extends from a point beyond the proximal end to a point beyond the distal end of the catheter product. The sheet material of the package is wrapped about the catheter product in a manner defining confronting proximal end edges, confronting distal end edges, and confronting side edges. The confronting proximal end edges, distal end edges and side edges of the sheet material are joined by a seal after the sheet material is wrapped about the catheter product to define a sealed cavity. The sheet material has a tear strip affixed to it which causes the sheet material to tear along the tear strip to thereby cause the package to open along an intended opening line. A method of forming a package for a catheter product comprises the steps of providing a sheet material for the package and placing the catheter product on the sheet material. It also includes affixing a tear strip to the sheet material and wrapping the sheet material around the catheter product. Further, the method includes the step of sealing the sheet material to form a sealed cavity with the catheter product being disposed within the sealed cavity.
    • 导管产品包装及其形成方法,其中包装包括围绕导管产品缠绕的片材以形成用于导管产品的包装。 导管产品在包装内大致纵向地延伸,并且片材从超过近端的点延伸到超过导管产品的远端的点。 包装的片材以围绕近端边缘,面对远端边缘和面对侧边缘的方式围绕导管产品缠绕。 在片材围绕导管产品缠绕以限定密封空腔之后,片材的面对的近端边缘,远端边缘和侧边缘通过密封件接合。 片材具有固定到其上的撕裂条,其导致片材沿着撕裂带撕裂,从而使包装沿着预期的开口线打开。 形成用于导管产品的包装的方法包括以下步骤:提供用于包装的片材材料并将导管产品放置在片材上。 它还包括将撕裂带固定在片材上并将片材缠绕在导管产品周围。 此外,该方法包括密封片材以形成密封空腔的步骤,导管产品设置在密封腔内。
    • 58. 发明申请
    • Environmental chamber and ultrasonic nebulizer assembly therefor
    • 环境室和超声波雾化器组装
    • US20060213508A1
    • 2006-09-28
    • US11087209
    • 2005-03-23
    • Michael MurrayBradley Stone
    • Michael MurrayBradley Stone
    • A61M11/00B05B17/06
    • B05B17/0615Y10S261/48
    • An environmental chamber includes an ultrasonic nebulizer assembly for controlling the relative humidity within the chamber. The ultrasonic nebulizer assembly is connected in closed-loop fluid communication with an enclosed chamber of the environmental chamber and includes an ultrasonic nebulizer module to generate water vapor that is introduced into the enclosed chamber. The ultrasonic nebulizer module is constructed to be immersed in water within the ultrasonic nebulizer assembly and is readily replaceable by the user. A nebulizer hour timer is provided to monitor the length of time of the ultrasonic nebulizer is operating to provide a precise indication to the user of how much life is left in the ultrasonic nebulizer before it needs to be replaced.
    • 环境室包括用于控制室内的相对湿度的超声雾化器组件。 超声雾化器组件与环境室的封闭腔室以闭环流体连通的方式连接,并且包括超声雾化器模块以产生引入封闭腔室的水蒸气。 超声雾化器模块被构造成浸入超声雾化器组件内的水中,并且可由用户容易地更换。 提供雾化器小时计时器来监视超声波雾化器正在操作的时间长度,以向用户提供在超声雾化器需要更换之前剩余多少寿命的精确指示。
    • 59. 发明申请
    • Removal of lipopolysaccharides from protein-lipopolysaccharide complexes by non flammable solvents.
    • 通过非易燃溶剂从蛋白质 - 脂多糖复合物中去除脂多糖。
    • US20060189790A1
    • 2006-08-24
    • US10561985
    • 2004-06-15
    • Philip RoppMichael Murray
    • Philip RoppMichael Murray
    • C07K14/765C07K14/785C07K14/47
    • C07K1/22B01D15/362B01D15/363B01D15/3804B01D15/426C07K1/18
    • During the production of recombinant proteins from gram negative bacteria, lipopolysaccharides (LPS, endotoxin) are released along with the protein of interest. In many instances, LPS will copurify with the target protein due to specific or non-specific protein-ILPS interactions. We have investigated the ability of alkanediols to effect the separation of LPS from protein-LPS complexes while the complexes are immobilized on anion or cation exchange chromatographic media. Alkanediols provide a safer alternative to the use of other organics such as alcohols or acetonitrile due to their lower toxicity and decreased flammability. In addition, they are less costly than many of the detergents that have been used for such purposes. LPS removal efficiency increased with increasing alkane chain length. 1,2-alkanediols were more effective than terminal alkanediols in the separation of LPS from protein LPS complexes.
    • 在从革兰氏阴性细菌生产重组蛋白质期间,脂多糖(LPS,内毒素)与感兴趣的蛋白质一起释放。 在许多情况下,由于特异性或非特异性蛋白质 - ILPS相互作用,LPS将与目标蛋白质融合。 我们已经研究了链烷二醇在将蛋白质 - LPS复合物固定在阴离子或阳离子交换色谱介质上时能够分解LPS的能力。 由于其较低的毒性和较低的易燃性,烷烃二醇为其他有机物如醇或乙腈提供了更安全的替代方案。 此外,它们比用于这些目的的许多洗涤剂成本低。 LPS去除效率随着烷烃链长度的增加而增加。 在分离LPS与蛋白质LPS复合物时,1,2-链烷二醇比末端链烷二醇更有效。