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1. 发明申请

US20080032316A1 TUMOR ASSOCIATED ANTIGENS AND METHODS OF USING THE SAME 审中-公开
标题翻译：肿瘤相关抗原及其使用方法
公开(公告)号：US20080032316A1
公开(公告)日：2008-02-07
申请号：US11697639
申请日：2007-04-06
申请人： Brad Nelson , Bradley Stone
发明人： Brad Nelson , Bradley Stone
IPC分类号： G01N33/574
CPC分类号： G01N33/574 , G01N33/564 , G01N33/6854
摘要： The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease.
摘要翻译：本发明提供了用于诊断过度增殖性疾病和自身免疫疾病的方法和组合物。肿瘤相关抗原，编码它们的核酸和与肿瘤相关抗原的抗体被提供用于诊断过度增殖性疾病，例如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其它上皮癌，并且对于诊断自身免疫性疾病。

2. 发明申请

US20070248440A1 YIELDABLE BRACE FOR A VEHICLE AT A LOADING DOCK 有权
标题翻译：用于装载车辆的车辆的可接合的衣架
公开(公告)号：US20070248440A1
公开(公告)日：2007-10-25
申请号：US11772445
申请日：2007-07-02
申请人： Jonathan Andersen , Dave Holm , Timothy Muhl , Bradley Stone , Matt Sveum
发明人： Jonathan Andersen , Dave Holm , Timothy Muhl , Bradley Stone , Matt Sveum
IPC分类号： B65G69/00
CPC分类号： B65G69/003
摘要： To help hold a trailer bed of a truck steady at a loading dock as the truck is being loaded or unloaded of its cargo, a yieldable vehicle brace exerts a substantial, but limited, reactive force upward against the trailer's rear impact guard to resist the trailer's downward movement. In some embodiments, the brace holds the trailer bed stationary up to a certain load limit and provides the trailer bed with a controlled or dampened descent when the load exceeds that limit. In some cases, the reactive upward force exerted by the brace increases with the downward velocity of the trailer bed. The reactive force can be created by one or more pressure relief valves, hydraulic fluid passing through a flow restriction, a brake, a spring, or various combinations thereof. Some embodiments of the brace include provisions for accommodating horizontal movement of the rear impact guard.
摘要翻译：为了在卡车正在装载或卸载货物时，帮助卡车稳定在卡车的拖车床上，可屈服的车辆支架将大量但有限的反作用力向上靠在拖车的后部撞击防护装置上，以抵抗拖车的向下运动。在一些实施例中，支架将拖车床固定住至一定的负载极限，并且当负载超过该限制时，向拖车床提供受控或阻尼的下降。在一些情况下，由支架施加的反作用向上的力随着拖车床的向下速度而增加。反作用力可以由一个或多个泄压阀，通过流量限制器，制动器，弹簧或其各种组合的液压流体产生。支架的一些实施例包括用于容纳后部防撞件的水平运动的装置。

3. 发明申请

US20070077556A1 TUMOR ASSOCIATED ANTIGENS AND METHODS OF USING THE SAME 失效
标题翻译：肿瘤相关抗原及其使用方法
公开(公告)号：US20070077556A1
公开(公告)日：2007-04-05
申请号：US10106559
申请日：2002-03-25
申请人： Brad Nelson , Bradley Stone
发明人： Brad Nelson , Bradley Stone
IPC分类号： C12Q1/68 , G01N33/574
CPC分类号： G01N33/574 , G01N33/564 , G01N33/6854
摘要： The present invention provides methods and compositions for the diagnosis of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis of autoimmune disease.
摘要翻译：本发明提供了用于诊断过度增殖性疾病和自身免疫疾病的方法和组合物。肿瘤相关抗原，编码它们的核酸和与肿瘤相关抗原的抗体被提供用于诊断过度增殖性疾病，例如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其它上皮癌，并且对于诊断自身免疫性疾病。

4. 发明申请

US20050221305A1 Antigen panels and methods of using the same 审中-公开
标题翻译：抗原面板及其使用方法
公开(公告)号：US20050221305A1
公开(公告)日：2005-10-06
申请号：US10494874
申请日：2002-11-12
申请人： Brad Nelson , Bradley Stone
发明人： Brad Nelson , Bradley Stone
IPC分类号： A61K38/17 , A61K38/46 , A61K38/52 , C12Q1/68 , G01N33/564 , G01N33/574
CPC分类号： G01N33/57488 , C12Q1/6837 , C12Q1/6886 , C12Q2600/112 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158 , G01N33/564 , G01N33/57449
摘要： The present invention provides methods and compositions for the diagnosis, prognosis and treatment of hyperproliferative disease and autoimmune disease. Tumor associated antigens, nucleic acids encoding them and antibodies to the tumor associated antigens are provided for the diagnosis, prognosis and treatment of hyperproliferative disease, such as, for example, ovarian cancer, breast cancer, lung cancer, colorectal cancer, and other epithelial cancers, and for the diagnosis, prognosis and treatment of autoimmune disease.
摘要翻译：本发明提供了用于诊断，预后和治疗过度增殖性疾病和自身免疫疾病的方法和组合物。提供肿瘤相关抗原，编码它们的核酸和抗肿瘤相关抗原的抗体，用于诊断，预后和治疗过度增殖性疾病，如卵巢癌，乳腺癌，肺癌，结肠直肠癌和其他上皮癌，以及自身免疫性疾病的诊断，预后和治疗。

5. 发明申请

US20060215487A1 Platform shaker for CO2 environment 有权
标题翻译：平台摇床用于二氧化碳环境
公开(公告)号：US20060215487A1
公开(公告)日：2006-09-28
申请号：US11086978
申请日：2005-03-22
申请人： Lawrence Stalec , Bradley Stone
发明人： Lawrence Stalec , Bradley Stone
IPC分类号： B01F11/00
CPC分类号： B01F11/0005
摘要： A platform shaker for use in a CO2 rich environment that has a corrosion resistant output shaft and a corrosion resistant, sealed motor casing. An eccentric drive assembly is connected between the output shaft and a platform and has components treated with a corrosion inhibiting coating. A shaker control controls the electric motor has components treated with a conformal coating.
摘要翻译：一种用于富含CO 2环境的平台振动筛，具有耐腐蚀输出轴和耐腐蚀密封的电机外壳。偏心驱动组件连接在输出轴和平台之间，并具有用腐蚀抑制涂层处理的部件。振动器控制控制电动机具有用保形涂层处理的部件。

6. 发明申请

US20060213508A1 Environmental chamber and ultrasonic nebulizer assembly therefor 有权
标题翻译：环境室和超声波雾化器组装
公开(公告)号：US20060213508A1
公开(公告)日：2006-09-28
申请号：US11087209
申请日：2005-03-23
申请人： Michael Murray , Bradley Stone
发明人： Michael Murray , Bradley Stone
IPC分类号： A61M11/00 , B05B17/06
CPC分类号： B05B17/0615 , Y10S261/48
摘要： An environmental chamber includes an ultrasonic nebulizer assembly for controlling the relative humidity within the chamber. The ultrasonic nebulizer assembly is connected in closed-loop fluid communication with an enclosed chamber of the environmental chamber and includes an ultrasonic nebulizer module to generate water vapor that is introduced into the enclosed chamber. The ultrasonic nebulizer module is constructed to be immersed in water within the ultrasonic nebulizer assembly and is readily replaceable by the user. A nebulizer hour timer is provided to monitor the length of time of the ultrasonic nebulizer is operating to provide a precise indication to the user of how much life is left in the ultrasonic nebulizer before it needs to be replaced.
摘要翻译：环境室包括用于控制室内的相对湿度的超声雾化器组件。超声雾化器组件与环境室的封闭腔室以闭环流体连通的方式连接，并且包括超声雾化器模块以产生引入封闭腔室的水蒸气。超声雾化器模块被构造成浸入超声雾化器组件内的水中，并且可由用户容易地更换。提供雾化器小时计时器来监视超声波雾化器正在操作的时间长度，以向用户提供在超声雾化器需要更换之前剩余多少寿命的精确指示。

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