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51. 发明授权

US5102985A Process for the formation of intramolecular disulfide bridge in a polypeptide 失效
标题翻译：在多糖中形成分子间桥的方法
公开(公告)号：US5102985A
公开(公告)日：1992-04-07
申请号：US417323
申请日：1989-10-04
申请人： Mineo Niwa , Masakazu Kobayashi , Yoshinori Ishii , Ikuo Ueda
发明人： Mineo Niwa , Masakazu Kobayashi , Yoshinori Ishii , Ikuo Ueda
IPC分类号： C07K1/02 , C07K1/00 , C07K1/113 , C07K1/12 , C07K14/00 , C07K14/52 , C07K14/525 , C07K14/54 , C07K14/55 , C07K14/575 , C07K14/58 , C07K14/655
CPC分类号： C07K1/12
摘要： The cysteine-containing polypeptide is oxidized with hydrogen peroxide to produce the biologically active polypeptide having the intramolecular disulfide bridge.

52. 发明授权

US4831525A Method of generating a source program from inputted schematic information 失效
标题翻译：从输入的原理图信息生成源程序的方法
公开(公告)号：US4831525A
公开(公告)日：1989-05-16
申请号：US145410
申请日：1988-01-19
申请人： Kazumasa Saito , Hiroyuki Maezawa , Masakazu Kobayashi , Yoshihiko Futamura
发明人： Kazumasa Saito , Hiroyuki Maezawa , Masakazu Kobayashi , Yoshihiko Futamura
IPC分类号： G06F9/06 , G06F9/44
CPC分类号： B82Y15/00 , G06F8/30 , Y10S715/967
摘要： According to the present invention, using a display terminal for conversation, a module structure diagram (schemata expressive of the connectional relations among respective program modules) is created, and a processing flow diagram (a kind of processing flow chart), an internal data definition diagram (schemata for specifying the formats etc. of data for use in processes) and an interface data definition diagram (schemata for specifying the formats etc. of arguments, common data between the modules, etc.) are created for each module, the created contents being stored in a memory. Further, the schematic information items of the module structure diagram, processing flow diagram, internal data definition diagram and interface data definition diagram are read out from the memory for each module and have stereotyped sentences and symbols added thereto, to generate the individual sentences of a source program. These sentences are edited according to the rules of a language, to complete the source program. If necessary, the various diagrams are printed out and utilized as program specifications.
摘要翻译：根据本发明，使用显示终端进行会话，形成模块结构图（表示各程序模块之间的连接关系的模式），处理流程图（处理流程图的种类），内部数据定义为每个模块创建图表（用于指定用于进程的数据的格式等）和接口数据定义图（用于指定参数的格式等的模式，模块之间的公共数据等），创建内容被存储在存储器中。此外，模块结构图，处理流程图，内部数据定义图和接口数据定义图的原理图信息项目从每个模块的存储器中读出，并添加了刻板的句子和符号，以生成单个句子源程序。这些句子根据语言的规则进行编辑，以完成源程序。如果需要，各种图表被打印出来并用作程序规格。

53. 发明授权

US4802286A Method and apparatus for freeze drying 失效
标题翻译：冷冻干燥方法和装置
公开(公告)号：US4802286A
公开(公告)日：1989-02-07
申请号：US154151
申请日：1988-02-09
申请人： Masakazu Kobayashi , Konomi Harashima , Hiroichi Ariyama
发明人： Masakazu Kobayashi , Konomi Harashima , Hiroichi Ariyama
IPC分类号： F26B5/06
CPC分类号： F26B5/06
摘要： In the freeze drying method of the present invention, a predetermined amount of water is poured on the refrigerating/heating surface provided in the drying chamber, which surface is cooled to a temperature below 0.degree. C., so that an ice film is formed on the refrigerating/heating surface. After that, while the thus formed ice film is kept at a temperature below 0.degree. C., a liquid material is supplied to the surface of the ice film so that a frozen layer of the liquid material is formed on the surface of the ice film. Under such circumstances, a vacuum is produced in the drying chamber to conduct the freeze drying operation of the frozen material in a vacuum environment.
摘要翻译：在本发明的冷冻干燥方法中，将规定量的水倒在设置在干燥室内的冷冻加热面上，将该表面冷却至0℃以下，使冰膜形成在制冷/加热面。之后，将这样形成的冰膜保持在低于0℃的温度下，将液体材料供给到冰膜的表面，使得在冰膜的表面上形成液态物质的冻结层。在这种情况下，在干燥室中产生真空，以在真空环境中进行冷冻材料的冷冻干燥操作。

54. 发明授权

US4379922A Cepham compounds 失效
标题翻译： Cepham化合物
公开(公告)号：US4379922A
公开(公告)日：1983-04-12
申请号：US213217
申请日：1980-12-05
申请人： Ikuo Ueda , Takao Takaya , Masakazu Kobayashi , Takashi Masugi , Hisashi Takasugi , Hiromu Kochi , Tadashi Kitaguchi
发明人： Ikuo Ueda , Takao Takaya , Masakazu Kobayashi , Takashi Masugi , Hisashi Takasugi , Hiromu Kochi , Tadashi Kitaguchi
IPC分类号： C07D317/30 , C07D319/06 , C07D501/04 , C07D501/14
CPC分类号： C07D317/30 , C07D319/06
摘要： This invention relates to new compounds comprising alkoxyimino dioxy butyric acid cepham derivatives, useful as intermediates in the production of antimicrobial agents.
摘要翻译：本发明涉及包含烷氧基亚氨基二氧基丁酸头孢类衍生物的新化合物，其可用作生产抗微生物剂的中间体。

55. 发明授权

US4251558A Method of making granular bean paste 失效
标题翻译：制备粒状豆酱的方法
公开(公告)号：US4251558A
公开(公告)日：1981-02-17
申请号：US64089
申请日：1979-08-06
申请人： Masakazu Kobayashi , Kenji Abo , Koh Harashima
发明人： Masakazu Kobayashi , Kenji Abo , Koh Harashima
IPC分类号： A23L11/00 , A23B4/04
CPC分类号： A23L11/05
摘要： Bean paste having a good plasticity is advantageously made to granules through the transformation to strips, without any fear of coagulation thereof into a mass, on account of the bean paste being made to strips by an extrusion under such vacuum which excites immediate dryness and cooling of stripped bean paste.
摘要翻译：具有良好塑性的豆浆有利地通过转化成条带而制成颗粒，而不用担心将其凝结成团块，这是由于在这样的真空下通过挤出制成的豆酱被剥去，从而激发立即干燥和冷却剥皮豆酱。

56. 发明授权

US4177574A Method and apparatus for granulating hydrated materials including food stuffs 失效
标题翻译：用于造粒包括食物在内的水合材料的方法和装置
公开(公告)号：US4177574A
公开(公告)日：1979-12-11
申请号：US885796
申请日：1978-03-13
申请人： Masakazu Kobayashi , Koh Harashima
发明人： Masakazu Kobayashi , Koh Harashima
IPC分类号： A23G7/00 , A23L1/00 , A23L1/202 , A23P1/02 , A61K9/16 , B01J2/20 , F26B7/00
CPC分类号： B01J2/20 , A23P10/25 , A61K9/16
摘要： Hydrated materials such as bean paste are controlled as to their moisture content to an intermediate moisture content such as 12% to 40% on dry basis and higher than their plastic limit, and are then extruded into strips under vacuum, followed by the granulation of said strips under vacuum by applying thereto mechanical shearing force to produce granules of desired sizes.
摘要翻译：将水合物如豆酱控制为其水分含量至中等水分含量，例如干基的12％至40％，高于其塑料极限，然后在真空下挤出成条，然后将所述通过施加机械剪切力在真空下制造条以产生所需尺寸的颗粒。

57. 发明授权

US09176881B2 Computer system and storage control method 有权
标题翻译：计算机系统和存储控制方法
公开(公告)号：US09176881B2
公开(公告)日：2015-11-03
申请号：US13577165
申请日：2012-01-26
申请人： Masakazu Kobayashi , Hiroshi Nojima , Takuya Okamoto
发明人： Masakazu Kobayashi , Hiroshi Nojima , Takuya Okamoto
IPC分类号： G06F12/08
CPC分类号： G06F12/0866 , G06F2212/314
摘要： The entirety or a part of free space of a second storage device included in a host computer is used as a cache memory region (external cache) outside of a storage apparatus. If Input/Output (I/O) in the host computer is Write, a Write request is transmitted from the host computer to a storage apparatus, the storage apparatus writes data associated with the Write request into a main cache that is a cache memory region included in this storage apparatus, and the storage apparatus writes the data in the main cache into a first storage device included in the storage apparatus. The storage apparatus writes the data in the main cache into an external cache included in the host computer. If the I/O in the host computer is Read, the host computer determines whether or not Read data as target data of the Read exists in the external cache. If a result of the determination is positive, the host computer reads the Read data from the external cache.
摘要翻译：包含在主计算机中的第二存储装置的可用空间的整体或一部分被用作在存储装置之外的高速缓冲存储器区域（外部高速缓存）。如果主计算机中的输入/输出（I / O）为写入，则从主计算机向存储装置发送写请求，存储装置将与写请求相关联的数据写入作为高速缓冲存储器区域的主缓存包括在该存储装置中，并且存储装置将数据存储在主高速缓存中，以包含在存储装置中的第一存储装置中。存储装置将主缓存中的数据写入包含在主计算机中的外部高速缓存。如果主计算机中的I / O为读取，则主机确定读取数据作为Read的目标数据是否存在于外部缓存中。如果确定结果为肯定，则主机从外部缓存读取读取数据。

58. 发明申请

US20140294869A1 IMMUNE TOLERANCE INDUCER 有权
标题翻译：免疫耐受性感应器
公开(公告)号：US20140294869A1
公开(公告)日：2014-10-02
申请号：US14237763
申请日：2012-07-13
申请人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
发明人： Ko Rii , Kazuo Sakurai , Masakazu Kobayashi , Hironori Ando , Sadaharu Higuchi , Shiro Takahara
IPC分类号： A61K39/00 , C12N15/113
CPC分类号： A61K39/0013 , A61K31/7105 , A61K31/716 , A61K2039/57 , C12N15/111 , C12N15/113 , C12N15/1138 , C12N2310/315 , C12N2320/32 , C12N2320/50 , C12N2310/14 , C12N2310/3519
摘要： An object of the present invention is to provide a drug and a method for effectively inducing donor-specific immune tolerance in a recipient in transplantation therapy. A complex of an siRNA for a costimulatory factor and schizophyllan is delivered to a Dectin-1 expressing cell which specifically recognizes schizophyllan to regulate the function of the Dectin-1 expressing cell, and therefore can induce immunosuppression effect as well as induce immune tolerance effectively.
摘要翻译：本发明的目的是提供在移植治疗中在受体中有效诱导供体特异性免疫耐受性的药物和方法。将共刺激因子和裂刺菌素的siRNA复合物递送到表达Dectin-1的细胞中，该细胞特异性地识别裂殖酵母以调节Dectin-1表达细胞的功能，因此可以有效地诱导免疫抑制作用以及诱导免疫耐受。

59. 发明授权

US08663832B2 Cell for reducing short circuit and battery incorporating the cell 有权
标题翻译：用于减少短路的电池和并入电池的电池
公开(公告)号：US08663832B2
公开(公告)日：2014-03-04
申请号：US12190133
申请日：2008-08-12
申请人： Takaaki Abe , Kazuki Miyatake , Osamu Shimamura , Masakazu Kobayashi , Hideaki Horie , Kyoichi Watanabe , Yoshio Shimoida
发明人： Takaaki Abe , Kazuki Miyatake , Osamu Shimamura , Masakazu Kobayashi , Hideaki Horie , Kyoichi Watanabe , Yoshio Shimoida
IPC分类号： H01M2/14 , H01M2/16 , H01M2/18
CPC分类号： H01M4/661 , H01M2/26 , H01M2/34 , H01M10/052 , H01M10/4235
摘要： Disclosed is a cell with a power-generating element and an outer package. The power-generating element includes a unit cell layer including a first electrode, a second electrode and an electrolyte layer disposed between the first and second electrodes. In the first electrode, a first collector is provided with one of a positive electrode active material layer and a negative electrode active material layer. In the second electrode, a second collector is provided with the other one of the positive and negative electrode active material layers. The first and second collectors have thicknesses such that when a conductor from outside penetrates at least two cells and a short circuit is formed between two cells via the conductor, shorted portions of the first and second collectors are fused by the heat generated by the current before the temperature of the cells reaches a predetermined value so that the short circuit is blocked.
摘要翻译：公开了具有发电元件和外包装的电池。发电元件包括单元电池层，其包括设置在第一和第二电极之间的第一电极，第二电极和电解质层。在第一电极中，第一集电体设置有正极活性物质层和负极活性物质层之一。在第二电极中，第二集电体设置有正极活性物质层和负极活性物质层中的另一个。第一和第二集电体具有这样的厚度，使得当来自外部的导体穿过至少两个电池并且经由导体在两个电池之间形成短路时，第一和第二集电器的短路部分被由电流产生的热量熔化电池的温度达到预定值，使得短路被阻塞。

60. 发明申请

US20120241814A1 POWER SEMICONDUCTOR DEVICE 审中-公开
标题翻译：功率半导体器件
公开(公告)号：US20120241814A1
公开(公告)日：2012-09-27
申请号：US13425250
申请日：2012-03-20
申请人： Shuji KAMATA , Masakazu Kobayashi
发明人： Shuji KAMATA , Masakazu Kobayashi
IPC分类号： H01L29/739
CPC分类号： H01L29/7397 , H01L29/0834 , H01L29/51
摘要： A power semiconductor device includes a p-type collector layer, an n-type base layer, a p-type base layer, an n-type source layer, and a gate electrode. The gate electrode is formed in a trench running from a surface of the n-type source layer through the n-type source layer and the p-type base layer to an interior of the n-type base layer via a gate insulating film. The gate electrode includes a first portion and a second portion. The first portion is opposed to a bottom end portion of the p-type base layer. The second portion is opposed to an upper end portion of the p-type base layer. The gate electrode is formed such that a threshold at the bottom end portion of the p-type base layer is not less than a threshold at the upper end portion of the p-type base layer.
摘要翻译：功率半导体器件包括p型集电极层，n型基极层，p型基极层，n型源极层和栅电极。栅电极形成在从n型源极的表面通过n型源极层和p型基极层经由栅极绝缘膜向n型基极层的内部延伸的沟槽中。栅电极包括第一部分和第二部分。第一部分与p型基底层的底端部分相对。第二部分与p型基底层的上端部相对。栅电极形成为使p型基极层的底端部的阈值为p型基底层的上端部的阈值以上。

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