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41. 发明申请

US20160317750A1 ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置和药物递送装置的组装
公开(公告)号：US20160317750A1
公开(公告)日：2016-11-03
申请号：US15105727
申请日：2014-12-18
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Michael Jugl , Axel Teucher , Marc Holtwick
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/31513 , A61M5/20 , A61M5/2033 , A61M5/31553 , A61M5/31583 , A61M5/482 , A61M2005/2086 , A61M2005/3126
摘要： An assembly for a drug delivery device (1) is described comprising at least one drive member (19, 26) adapted and arranged to be moved in a delivery direction during a dose delivery operation of the assembly and in a direction opposite to the delivery direction during a dose setting operation of the assembly, an energy storing member (16) adapted and arranged to store energy and to cause movement of the drive member (19, 26) in the delivery direction, and an interaction system adapted and arranged to generate a friction onto the drive member (19, 26), wherein an amount of friction regulates a speed of movement of the drive member (19, 26) when drive member (19, 26) is moved in the delivery direction. Furthermore, a drug delivery device comprising the assembly is described.
摘要翻译：描述了一种用于药物输送装置（1）的组件，其包括至少一个驱动构件（19,26），该驱动构件适于并布置成在组件的剂量递送操作期间沿与输送方向相反的方向在输送方向上移动在组件的剂量设定操作期间，能量存储部件（16）适于和布置成储存能量并且使驱动部件（19,26）在传送方向上移动，以及相互作用系统，其适于和布置成产生驱动构件（19,26）上的摩擦力，其中当驱动构件（19,26）沿输送方向移动时，摩擦量调节驱动构件（19,26）的移动速度。此外，描述了包括组件的药物递送装置。

42. 发明申请

US20160317749A1 ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置和药物递送装置的组装
公开(公告)号：US20160317749A1
公开(公告)日：2016-11-03
申请号：US15105251
申请日：2014-12-18
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Michael Jugl , Axel Teucher , Marc Holtwick
IPC分类号： A61M5/315 , A61M5/20
CPC分类号： A61M5/31513 , A61M5/20 , A61M5/2033 , A61M5/31501 , A61M5/31511 , A61M5/31553 , A61M5/31583 , A61M2005/2086 , A61M2005/3151 , A61M2005/3152
摘要： An assembly for a drug delivery device (1) is described comprising a piston rod (12) adapted and arranged to be displaceable in a delivery direction for dispensing a dose of a drug (10) from the device (1), an energy storing member (16) which is adapted and arranged to store energy and to move the piston rod (12) in the delivery direction, and an interaction member (7) adapted and arranged to mechanically cooperate with the piston rod (12), wherein the interaction member (7) is displaceable between a first position and a second position with respect to the piston rod (12), wherein the interaction member (7) is configured to be moved from the first position towards the second position to increase a friction onto the piston rod (12) and, wherein the interaction member (7) is configured to be moved from the second position back into the first position to decrease the friction onto the piston rod (12). Furthermore, a drug delivery device (1) comprising the assembly is described.
摘要翻译：描述了一种用于药物输送装置（1）的组件，包括适于并布置成可在输送方向上移位的活塞杆（12），用于从装置（1）分配剂量的药物（10），能量存储构件（16），其适于并布置成储存能量并沿输送方向移动活塞杆（12）;以及相互作用构件（7），其适于并布置成与活塞杆（12）机械配合，其中相互作用构件（7）可相对于活塞杆（12）在第一位置和第二位置之间移动，其中所述相互作用构件（7）构造成从所述第一位置向所述第二位置移动以增加对所述活塞的摩擦杆（12），并且其中所述相互作用构件（7）构造成从所述第二位置移动到所述第一位置以减小对所述活塞杆（12）的摩擦。此外，描述了包括组件的药物输送装置（1）。

43. 发明申请

US20160296711A1 DRUG DELIVERY DEVICE WITH DOSE KNOB CLUTCH 审中-公开
标题翻译：药物递送装置，带有针头离合器
公开(公告)号：US20160296711A1
公开(公告)日：2016-10-13
申请号：US15036525
申请日：2014-11-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stefan Blancke , Axel Teucher
IPC分类号： A61M5/315 , A61M5/24 , A61M5/31 , A61M5/32
摘要： An assembly for a drug delivery device and an associated drug delivery device are provided. The device has a drug delivery device housing and a medicament contained in the drug delivery device housing. A clutch is established between the dose knob and the dial link to prevent inadvertent proximal axial movement of the lead screw away from the cartridge piston, which can lead to dosing inaccuracies.
摘要翻译：提供了用于药物递送装置和相关联的药物递送装置的组件。该装置具有药物输送装置壳体和药物输送装置壳体中所含的药物。在剂量旋钮和表盘连接件之间建立了一个离合器，以防止导螺杆远离盒式活塞的无意的近端轴向移动，这可能导致配量不准确。

44. 发明申请

US20160287803A1 DRUG DELIVERY DEVICE WITH END OF DOSE FEEDBACK 有权
标题翻译：具有剂量反馈末端的药物递送装置
公开(公告)号：US20160287803A1
公开(公告)日：2016-10-06
申请号：US15036528
申请日：2014-11-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315
CPC分类号： A61M5/31551 , A61M5/24 , A61M5/28 , A61M5/3146 , A61M5/31558 , A61M5/31561 , A61M5/3157 , A61M5/31575 , A61M5/31578 , A61M5/31585 , A61M5/31593 , A61M2005/3104 , A61M2205/581 , A61M2205/582
摘要： A method and an assembly for providing a drug delivery device is presented. The assembly includes a housing and an end of dose feedback connection provides the user with an audible and/or tactile signal to indicate that the drug delivery is completed. A first section of the end of dose feedback connection is located on a distal portion of an inner sleeve and a second section of the end of dose feedback connection is located on the mid-body.
摘要翻译：提出了一种用于提供药物递送装置的方法和组件。该组件包括壳体，并且剂量反馈连接的结束为使用者提供了可听和/或触觉的信号，以指示药物递送完成。剂量反馈连接结束的第一部分位于内套筒的远端部分上，剂量反馈连接端的第二部分位于中间体上。

45. 发明申请

US20150202016A1 Impact-Resistant Fastening Assembly for a Medical Device 审中-公开
标题翻译：医疗器械的抗冲击紧固组件
公开(公告)号：US20150202016A1
公开(公告)日：2015-07-23
申请号：US14424374
申请日：2013-08-28
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61B19/00 , A61M5/24 , A61B5/00 , A61M5/142 , A61B5/145
CPC分类号： A61B5/6835 , A61B5/0002 , A61B5/14532 , A61B5/742 , A61B90/50 , A61B90/57 , A61B2560/0431 , A61B2560/0443 , A61B2562/18 , A61M5/14244 , A61M5/24 , A61M5/3129 , A61M2005/14264 , A61M2205/0216 , A61M2205/273 , A61M2205/276 , A61M2207/00 , A61M2230/201
摘要： The present invention relates to a fastening assembly for a medical device and to a respective medical device, wherein the fastening assembly comprises a support structure and a device component releasably fastenable to the support structure by means of mutually corresponding fastening members being adapted to abrogate an interconnection of the device component and the support structure when becoming subject to a force effect or a mechanical impact above a predefined threshold.
摘要翻译：本发明涉及一种用于医疗装置和相应的医疗装置的紧固组件，其中紧固组件包括支撑结构和装置部件，该部件可通过相应对应的紧固部件可释放地固定到支撑结构上，该紧固部件适于消除互连当受到超过预定阈值的力作用或机械冲击时，装置部件和支撑结构。

46. 发明申请

US20150161339A1 MEDICAL SYSTEM 审中-公开
标题翻译：医疗系统
公开(公告)号：US20150161339A1
公开(公告)日：2015-06-11
申请号：US14418204
申请日：2013-08-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Axel Teucher , Frank Roethke , Florian Schauderna , Marcus-Meinolf Dittrich , Andrew Tubb , Timothy Golnik , Joseph Flaherty
IPC分类号： G06F19/00 , G06F17/30 , A61M5/172 , H04L29/08
摘要： The invention refers to a medical device for supporting health control. In order to provide safe access to a dose helper functionality, the device has a first storage means arranged to store an initial data matrix with at least one initial parameter set containing at least two initial data entries for one parameter of the dose helper functionality; receiving means arranged to receive initialization data and/or security data, preferably from a second storage means, for example provided by a hardware key; selecting means operable to select based at least in part on the initialization data one data entry for each initial parameter set as initial data or one initial parameter template containing a reference to one data entry for each initial parameter set as initial data; and first activation means arranged to activate, preferably based at least in part on the security data, execution of the dose helper functionality based on the selected initial data. The invention further refers to a respective medical system, a method for providing such information, a respective computer program and a respective computer program product.
摘要翻译：本发明涉及用于支持健康控制的医疗装置。为了提供对剂量辅助功能的安全访问，设备具有第一存储装置，其被布置为存储具有至少一个初始参数集的初始数据矩阵，该初始参数集包含用于剂量辅助功能的一个参数的至少两个初始数据条目; 接收装置，优选地从第二存储装置接收例如由硬件密钥提供的初始化数据和/或安全数据; 选择装置，用于至少部分地基于所述初始化数据选择作为初始数据的每个初始参数的一个数据条目或者包含对作为初始数据的每个初始参数集合的对一个数据条目的引用的一个初始参数模板; 以及第一激活装置，其被布置为基于所选择的初始数据，优选至少部分地基于所述安全数据激活所述剂量帮助器功能的执行。本发明还涉及相应的医疗系统，用于提供这种信息的方法，相应的计算机程序和相应的计算机程序产品。

47. 发明申请

US20140138244A1 TEST STRIP FOR A MEDICAL METER 审中-公开
标题翻译：医疗仪器测试条
公开(公告)号：US20140138244A1
公开(公告)日：2014-05-22
申请号：US14131077
申请日：2012-07-06
申请人： SANOFI-AVENTIS DEUTSCHLAND GmbH
发明人： Axel Teucher , Michael Jugl
IPC分类号： G01N27/327
CPC分类号： G01N27/3272 , A61B5/145 , G01N33/4875
摘要： A test strip for a medical meter) capable of analysing a sample of a bodily fluid comprises a first end and a second end opposite to the first end. The test strip is made from a rigid material and comprises a bended portion that is located between the first and the second end.
摘要翻译：能够分析体液样品的用于医疗计量器的测试条包括与第一端相对的第一端和第二端。测试条由刚性材料制成并且包括位于第一和第二端之间的弯曲部分。

48. 发明授权

US11484662B2 Medicament injection device 有权
公开(公告)号：US11484662B2
公开(公告)日：2022-11-01
申请号：US15778263
申请日：2016-11-21
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Michael Jugl , Axel Teucher , Stefan Blancke , Michael Helmer , Marc Schader , Sebastian Braun
IPC分类号： A61M5/32 , A61M5/24 , A61M5/34 , A61M5/178 , A61M5/20
摘要： A medicament delivery device comprising: a main body arranged to receive a medicament cartridge sealed with a penetrable barrier; a needle carrier carrying a needle; a cap removably coupled to the needle carrier, a pre-stressed spring connected to the needle carrier and to the main body, wherein the pre-stressed spring is held by an activation element coupled to the cap, wherein the activation element is arranged to release the spring when the cap is pulled in a distal direction from the device, thereby causing the needle carrier to move axially in a proximal direction.

49. 发明申请

US20220059206A1 MEDICAL DEVICE WITH DOSE HELPER FUNCTIONALITY INCLUDING TIME ZONE OR LOCATION DETERMINATION 有权
公开(公告)号：US20220059206A1
公开(公告)日：2022-02-24
申请号：US17520502
申请日：2021-11-05
申请人： Sanofi-Aventis Deutschland GmbH
发明人： Axel Teucher , Frank Roethke , Florian Schauderna , Marcus-Meinolf Dittrich , Andrew Tubb , Timothy Golnik , Joseph Flaherty
IPC分类号： G16H20/17 , G06F16/22 , G16H40/63 , A61M5/172 , H04L29/08
摘要： A medical device for supporting health control is provided. An example medical device can include a receiver unit configured to receive information regarding a current location of the medical device or a current time-zone of the medical device, a user interface, a storage unit storing instructions, and one or more processors configured to execute the instructions to cause the medical device to perform operations. Examples of operations include determining a current location of the medical device and/or a current time zone of the medical device from the received information, providing a dose helper functionality employing a titration method to determine and/or recommend a basal long-acting insulin dose value or a corrective amount of basal long-acting insulin to be administered by a patient to the patient based on a measured physiological parameter, information about hyperglycemic events, the determined current location and/or current time zone of the medical device.

50. 发明授权

US11065389B2 Assembly for a drug delivery device 有权
公开(公告)号：US11065389B2
公开(公告)日：2021-07-20
申请号：US16373420
申请日：2019-04-02
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/32 , A61M5/31
摘要： An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed.

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