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1. 发明授权

US11587662B2 Medical system 有权
公开(公告)号：US11587662B2
公开(公告)日：2023-02-21
申请号：US14418204
申请日：2013-08-09
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Axel Teucher , Frank Roethke , Florian Schauderna , Marcus-Meinolf Dittrich , Andrew Tubb , Timothy Golnik , Joseph Flaherty
IPC分类号： G16H20/17 , G16H40/63 , G16H20/10 , A61M5/172 , H04L67/12 , G06F16/22
摘要： The invention refers to a medical device for supporting health control. In order to provide safe access to a dose helper functionality, the device has a first storage means arranged to store an initial data matrix with at least one initial parameter set containing at least two initial data entries for one parameter of the dose helper functionality; receiving means arranged to receive initialization data and/or security data, preferably from a second storage means, for example provided by a hardware key; selecting means operable to select based at least in part on the initialization data one data entry for each initial parameter set as initial data or one initial parameter template containing a reference to one data entry for each initial parameter set as initial data; and first activation means arranged to activate, preferably based at least in part on the security data, execution of the dose helper functionality based on the selected initial data. The invention further refers to a respective medical system, a method for providing such information, a respective computer program and a respective computer program product.

2. 发明授权

US11000649B2 Drug delivery device with dose delivery clicker 有权
公开(公告)号：US11000649B2
公开(公告)日：2021-05-11
申请号：US16572517
申请日：2019-09-16
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/24 , A61M5/31
摘要： An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.

3. 发明申请

US20200090798A1 DATA MANAGEMENT UNIT FOR SUPPORTING HEALTH CONTROL 审中-公开
公开(公告)号：US20200090798A1
公开(公告)日：2020-03-19
申请号：US16471892
申请日：2017-12-21
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Axel Teucher , Florian Schauderna , Jochen Sieber , Alexandra Beer , Frank Roethke , Andrew Tubb , Ashley Engelhardt , Joseph Pomata , Margaret Wiley , Thora Thorgilsdottir
IPC分类号： G16H10/65 , G16H20/13 , G16H20/17 , A61M5/172
摘要： A data management unit for supporting health control and avoiding wrong dose suggestion, the unit including: a processor to provide a dose helper functionality with regard to a predefined medicament, a display, a data input unit, a data storage, a clock unit adapted to determine the absolute time of a dose helper request received by the data input. The processor is adapted to initiate storing at least the time of a dose helper request that is outside the time range around the usual dose time in the data storage. The processor is further adapted to execute the dose helper functionality only if the time of the most recent dose helper request is within the dose time window around the usual dose time. The processor is further adapted to initiate sending a recommendation message for change of usual dose time and/or dose time window to the display.

4. 发明申请

US20200086060A1 DRUG DELIVERY DEVICE WITH DOSE KNOB CLUTCH 审中-公开
公开(公告)号：US20200086060A1
公开(公告)日：2020-03-19
申请号：US16690086
申请日：2019-11-20
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stefan Blancke , Axel Teucher
IPC分类号： A61M5/315 , A61M5/24 , A61M5/31 , A61M5/32
摘要： An assembly for a drug delivery device and an associated drug delivery device are provided. The device has a drug delivery device housing and a medicament contained in the drug delivery device housing. A clutch is established between the dose knob and the dial link to prevent inadvertent proximal axial movement of the lead screw away from the cartridge piston, which can lead to dosing inaccuracies.

5. 发明申请

US20200038592A1 DRUG DELIVERY DEVICE WITH DOSE DELIVERY CLICKER 审中-公开
公开(公告)号：US20200038592A1
公开(公告)日：2020-02-06
申请号：US16572517
申请日：2019-09-16
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/24
摘要： An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.

6. 发明申请

US20200001019A1 Injection Device 审中-公开
公开(公告)号：US20200001019A1
公开(公告)日：2020-01-02
申请号：US16569411
申请日：2019-09-12
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Axel Teucher , Michael Jugl
IPC分类号： A61M5/32
摘要： Described is an injection device (1) for administering a drug, the injection device (1) comprising a cartridge holder (2) adapted to receive a drug cartridge (3), a hollow injection needle (6) having a proximal tip (6.2) adapted to pierce a septum (4) of the cartridge (3) so as to establish a fluid communication between the cartridge (3) and the needle (6), and a cap (7) arrangeable over the cartridge holder (2) in a manner to cover the needle (6). In an initial state the cartridge (3) is arranged within the cartridge holder (2) with the septum (4) axially spaced from the proximal tip (6.2) of the needle (6). The cap (7) is adapted to move the needle (6) relative to the septum (4) for piercing it on movement of the cap (7) relative to the cartridge holder (2).

7. 发明授权

US10420890B2 Assembly for a drug delivery device and use of an attenuation member 有权
公开(公告)号：US10420890B2
公开(公告)日：2019-09-24
申请号：US14913188
申请日：2014-08-15
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Michael Jugl , Axel Teucher
IPC分类号： A61M5/315 , A61M5/24
摘要： An assembly for a drug delivery device includes a first member and an attenuation member. The first member includes a main body and an elastically displaceable feature connected to the main body. The attenuation member mechanically cooperates with the elastically displaceable feature to influence the force which has to be exerted on the elastically displaceable feature to displace the elastically displaceable feature elastically with respect to the main body. An attenuation member can be used in a drug delivery device to tune the force required to elastically displace an elastically displaceable feature of a first member of the drug delivery device by bringing the attenuation member into mechanical cooperation with the elastically displaceable feature.

8. 发明申请

US20190224420A1 Assembly for a Drug Delivery Device 审中-公开
公开(公告)号：US20190224420A1
公开(公告)日：2019-07-25
申请号：US16373420
申请日：2019-04-02
申请人： Sanofi-Aventis Deutschland GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/32
摘要： An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed.

9. 发明申请

US20160296706A1 DRUG DELIVERY DEVICE WITH DOSE DELIVERY CLICKER 审中-公开
标题翻译：药物递送装置，带有剂量递送点击者
公开(公告)号：US20160296706A1
公开(公告)日：2016-10-13
申请号：US15036529
申请日：2014-11-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/24
CPC分类号： A61M5/3157 , A61M5/24 , A61M5/31528 , A61M5/31551 , A61M5/3158 , A61M5/31585 , A61M5/31593 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： An assembly for a drug delivery device is provided comprising a housing, and a lead screw having a longitudinal axis, a distal end and a proximal end, the lead screw being rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing, the lead screw further including a thread. The assembly further comprises a drive nut threadedly engaged with and screwable along the lead screw thread and a dial link connected with the drive nut and axially movable and rotatably fixed relative to the drive nut, where the dial link comprises a first portion of a feedback ratchet. The assembly is configured such that, during dose delivery, the assembly generates a feedback signal.
摘要翻译：提供了一种用于药物输送装置的组件，其包括壳体和具有纵向轴线，远端和近端的导螺杆，所述导螺杆在剂量设定和剂量递送期间可旋转地固定，并且在远端方向相对轴向地可移动导向螺丝进一步包括螺纹。所述组件还包括与所述导螺纹螺纹螺纹接合并可旋拧的驱动螺母，以及与所述驱动螺母相连并且相对于所述驱动螺母可轴向移动和可旋转地固定的拨盘连杆，其中所述拨号连杆包括反馈棘轮的第一部分。组件被配置为使得在剂量递送期间，组件产生反馈信号。

10. 发明申请

US20160287799A1 Assembly for a Drug Delivery Device 审中-公开
标题翻译：药物输送装置的装配
公开(公告)号：US20160287799A1
公开(公告)日：2016-10-06
申请号：US15037339
申请日：2014-11-17
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH
发明人： Stefan Blancke , Axel Teucher , Michael Jugl , Christiane Schneider
IPC分类号： A61M5/315 , A61M5/32
摘要： An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed.
摘要翻译：提出了用于药物递送装置的组件。组件包括壳体和具有纵向轴线，远端和近端的活塞杆。活塞杆还包括活塞杆相互作用特征以及可相对于活塞杆移动的活塞杆引导件，活塞杆引导件还包括与活塞杆相互作用特征对应的引导相互作用特征，活塞杆引导件可与相对于活塞杆在组件的第一状态和第二状态之间切换，第二状态不同于第一状态。组件被构造成使得在组件的第一状态下，活塞杆引导件相对于活塞杆处于第一轴向位置，在该第一状态中活塞杆相互作用特征被布置成与引导相互作用特征相互作用以防止近端运动所述活塞杆相对于所述壳体处于第二轴向位置，并且其中在所述组件的第二状态不同于所述第一状态时，所述活塞杆导向件相对于所述活塞杆处于第二轴向位置，所述第二轴向位置不同于第一轴向位置，其中在第二轴向位置中，活塞杆相互作用特征和引导相互作用特征被布置成使得允许活塞杆相对于壳体的近端运动。

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