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41. 发明申请

US20130156364A1 ELECTRONIC/PHOTONIC INTEGRATED CIRCUIT ARCHITECTURE AND METHOD OF MANUFACTURE THEREOF 有权
标题翻译：电子/光电集成电路架构及其制造方法
公开(公告)号：US20130156364A1
公开(公告)日：2013-06-20
申请号：US13326583
申请日：2011-12-15
申请人： Long Chen , Pietro Bernasconi , Po Dong , Liming Zhang , Young-Kai Chen
发明人： Long Chen , Pietro Bernasconi , Po Dong , Liming Zhang , Young-Kai Chen
IPC分类号： G02B6/12 , H01L21/02
CPC分类号： G02B6/12004 , G02B6/12002 , G02B6/1228 , G02F1/015 , H01L27/15 , H01S5/026 , H01S5/0261
摘要： A device includes a passive photonic layer located over a substrate and including at least one passive photonic element configured to propagate an optical signal therein. An electronic layer located between said substrate and said passive photonic layer includes at least one electronic device configured to propagate an electrical signal therein. An active photonic layer located over said passive photonic layer includes an active photonic device optically coupled to said passive photonic element and configured to convert between said electrical signal and said optical signal.
摘要翻译：一种器件包括位于衬底上方的无源光子层，并且包括配置成在其中传播光信号的至少一个无源光子元件。位于所述衬底和所述无源光子层之间的电子层包括配置成在其中传播电信号的至少一个电子器件。位于所述无源光子层之上的有源光子层包括光学耦合到所述无源光子元件并被配置为在所述电信号和所述光信号之间转换的有源光子器件。

42. 发明申请

US20120177060A1 OPTICAL APPARATUS, METHOD, AND APPLICATIONS 有权
标题翻译：光学装置，方法和应用
公开(公告)号：US20120177060A1
公开(公告)日：2012-07-12
申请号：US13213666
申请日：2011-08-19
申请人： Michal Lipson , Bernado Kyotoku , Long Chen
发明人： Michal Lipson , Bernado Kyotoku , Long Chen
IPC分类号： H04J14/02 , G02B6/34 , G02B6/42
CPC分类号： H04J14/02 , G02B6/12007 , G02B6/29307 , G02B6/29308 , G02B6/2931 , H04J14/0201
摘要： A high resolution, wide spectral range, optical apparatus that includes an optical resonator cavity and a wavelength demultiplexer, arrangeable in multiple configurations. A method for increasing the resolution of a wavelength demultiplexer involves inputting light into an optical resonant cavity; inputting a plurality of different resonant output wavelengths to a wavelength demultiplexer; and routing each different resonant wavelength to a different output waveguide of the demultiplexer to generate a demultiplexer output spectrum. The method further involves performing either a time serialization or a space serialization procedure to increase the channel density and fully cover the spectrum of interest.
摘要翻译：高分辨率，宽光谱范围，包括光学谐振腔和波长解复用器的光学装置，可配置成多种配置。一种用于增加波分解复用器的分辨率的方法包括将光输入光谐振腔; 将多个不同的谐振输出波长输入到波长解复用器; 并将每个不同的谐振波长路由到解复用器的不同输出波导以产生解复用器输出频谱。该方法还涉及执行时间序列化或空间序列化过程以增加信道密度并完全覆盖感兴趣的频谱。

43. 发明申请

US20120163750A1 Planar Polarization Rotator 失效
标题翻译：平面极化旋转器
公开(公告)号：US20120163750A1
公开(公告)日：2012-06-28
申请号：US12976554
申请日：2010-12-22
申请人： Long Chen
发明人： Long Chen
IPC分类号： G02B6/126 , B29D11/00 , G02F1/035
CPC分类号： G02B6/2766 , B29D11/00644 , G02B6/105 , G02B6/126 , G02B6/136 , G02B27/281 , G02F1/011
摘要： An optical polarization rotator includes first and second optical waveguide ribs located along a planar surface of a substrate. The second optical waveguide rib is located farther from the surface than the first optical waveguide rib. First segments of the optical waveguide ribs form a vertical stack over the substrate, and second segments of the optical waveguide ribs are offset laterally in a direction along the planar surface. The first and second optical waveguide ribs are formed of materials with different bulk refractive indexes.
摘要翻译：光学偏振旋转器包括沿着基板的平面表面定位的第一和第二光波导肋。第二光波导肋比第一光波导肋远离表面。光波导肋的第一段在衬底上形成垂直堆叠，并且光波导肋的第二段沿着平坦表面的方向横向偏移。第一和第二光波导肋由具有不同体积折射率的材料形成。

44. 发明授权

US08158630B2 Application of 2,5 -dihydroxymethyl-3,6-dimethyl pyrazine and its derivates in pharmacy 有权
标题翻译： 2,5-二羟甲基-3,6-二甲基吡嗪及其衍生物在药学中的应用
公开(公告)号：US08158630B2
公开(公告)日：2012-04-17
申请号：US12703131
申请日：2010-02-09
申请人： Wei Li , Long Chen , Huimin Bian , Hongmei Wen , Zheng Liu
发明人： Wei Li , Long Chen , Huimin Bian , Hongmei Wen , Zheng Liu
IPC分类号： A61K31/4965
CPC分类号： A61K31/4965
摘要： An application of 2,5-dihydroxymethyl-3,6-dimethyl pyrazine and its derivatives in the preparation of drugs for the treatment of, prevention of, and/or protection from heart failure wherein the structural formula of the compound is as follows:
摘要翻译： 2,5-二羟甲基-3,6-二甲基吡嗪及其衍生物在制备用于治疗，预防和/或保护心力衰竭的药物中的应用，其中化合物的结构式如下：

45. 发明授权

US08117432B2 Method for controlling boot sequence of server 有权
标题翻译：控制服务器启动顺序的方法
公开(公告)号：US08117432B2
公开(公告)日：2012-02-14
申请号：US12267349
申请日：2008-11-07
申请人： Long Chen , Tom Chen
发明人： Long Chen , Tom Chen
IPC分类号： G06F9/00 , G06F11/00
CPC分类号： G06F9/4416
摘要： A method for controlling a boot sequence of a server includes the following steps. A boot image is created, and a first proxy server program is placed into the boot image. The first proxy server program communicates with a management server. The boot image is restored on a rewritable removable storage device, so as to enable the rewritable removable storage device to boot a managed target server. A second proxy server program is installed and executed in the management server. A basic input/output system (BIOS) of the target server is set to enable the rewritable removable storage device to act as a first boot device. Boot files in the rewritable removable storage device are modified through the first proxy server program or the second proxy server program according to a boot instruction received from the management server, thereby controlling a boot sequence of the target server.
摘要翻译：一种用于控制服务器的引导顺序的方法包括以下步骤。创建引导映像，并将第一个代理服务器程序放入引导映像。第一个代理服务器程序与管理服务器进行通信。引导映像在可重写可移动存储设备上恢复，以便使可重写可移动存储设备能够引导受管目标服务器。在管理服务器中安装并执行第二代理服务器程序。目标服务器的基本输入/输出系统（BIOS）设置为使可重写可移动存储设备充当第一启动设备。根据从管理服务器接收到的引导指令，通过第一代理服务器程序或第二代理服务器程序修改可重写可移动存储设备中的引导文件，从而控制目标服务器的引导顺序。

46. 发明申请

US20060132409A1 Driving method for active matrix liquid crystal display panel 有权
标题翻译：有源矩阵液晶显示面板的驱动方法
公开(公告)号：US20060132409A1
公开(公告)日：2006-06-22
申请号：US11311847
申请日：2005-12-19
申请人： Long Chen , Eddy Chen , Chih-Sheng Chang , Sz Chen , Tsau Hsieh , Jia-Pang Pang
发明人： Long Chen , Eddy Chen , Chih-Sheng Chang , Sz Chen , Tsau Hsieh , Jia-Pang Pang
IPC分类号： G09G3/36
CPC分类号： G09G3/3648 , G09G2310/0251 , G09G2310/061 , G09G2320/0252 , G09G2320/0261
摘要： A driving method for an active matrix liquid crystal display panel includes the following steps. First, a frame period is divided into a display period (t1) and a black insertion period (tr). A gray-scale voltage is generated according to a desired corresponding light transmittance of each pixel of the liquid crystal display panel; and during the display period, the gray-scale voltage is supplied to a corresponding pixel electrode of the liquid crystal display panel. Then during the black insertion period, a restoring voltage Vh is supplied to the pixel electrode, so that the pixel is returned to an initial black state. Accordingly, the quality of motion pictures of the liquid crystal display panel is good.
摘要翻译：有源矩阵液晶显示面板的驱动方法包括以下步骤。首先，帧周期被分为显示周期（t 1> 1）和黑插入周期（t SUB）。根据液晶显示面板的每个像素的期望的对应的透光率产生灰度电压; 并且在显示期间，将灰度电压提供给液晶显示面板的对应像素电极。然后在黑插入期间，向像素电极提供恢复电压V H h，使得像素返回到初始黑色状态。因此，液晶显示面板的运动画面的质量良好。

47. 发明授权

US12006353B2 Application of SCFV protein, car gene expression vector, CAR-T cell and application thereof 有权
公开(公告)号：US12006353B2
公开(公告)日：2024-06-11
申请号：US17872131
申请日：2022-07-25
申请人： Long Chen
发明人： Long Chen , Fake Yang , Fukun Chen , Huatao Niu , Yongzhu Pu , Jindan Li , Conghui Yang , Dongxue Chen
IPC分类号： C07K16/00 , C12N5/0783 , C12N15/86
CPC分类号： C07K16/00 , C12N5/0636 , C12N15/86 , C07K2317/622
摘要： An application of SCFV protein in preparation of a CAR gene expression vector is disclosed. The protein sequence of the SCFV protein is shown in SEQ ID No. 1. The 1st˜21st amino acids are the extracellular signal peptide amino acid sequences. The 22nd˜31st amino acids are Flag amino acid sequences. And the remaining sequences are CXCR4 scfv sequences. An application of the gene sequence encoding the SCFV protein in preparation of a CAR gene expression vector is disclosed, and the gene sequence is shown in SEQ ID No.2. A CAR gene expression vector and a CAR-T cell are disclosed. The expression vector is plent-EF1a-Flag-CXCR4 CAR, and CAR-T cells are used in the preparation of a drug for a targeted therapy of tumor cells with high expression of CXCR4.

48. 发明公开

US20230243832A1 METHOD OF USING CIRBP AS A MOLECULAR MARKER FOR DIAGNOSIS AND TREATMENT OF PANCREATIC CANCER 审中-公开
公开(公告)号：US20230243832A1
公开(公告)日：2023-08-03
申请号：US18297858
申请日：2023-04-10
申请人： Long CHEN
发明人： Long Chen , Chengde Liao , Hongqiang Gao , Fake Yang , Yong Zha , Yongzhu Pu , Jindan Li , Chengtao Feng , Yue Wang , Rong Huang , Qiuyuan Hu
IPC分类号： G01N33/574 , A01N1/02
CPC分类号： G01N33/57434 , A01N1/0284 , G01N2800/7028
摘要： A method of using CIRBP as a molecular marker for diagnosis and treatment of pancreatic cancer is disclosed. The method includes the following steps: S1: material preparation, S2: cell resuscitation, S3: cell culture, S4: experiment grouping, and S5: RIP to detect P CIRBP regulating TP53. For the method, the nucleoplasm expression of antibody is significantly inversely related to the tumor size of patients with pancreatic cancer, the paraneoplastic plasma expression of antibody is significantly inversely related to the diabetes history of patients with pancreatic cancer. In other words, the plasmas expression of antibody of the subgroup without a history of diabetes is significantly higher, the total survival of the pancreatic cancer patients with a high nuclear expression of the antibody is significantly better, and the survival of the pancreatic cancer with a high expression of the target gene in the database query is significantly better for inhibiting cancer.

49. 发明授权

US09146349B2 Monolithic integration of dielectric waveguides and germanium-based devices 有权
标题翻译：介质波导和基于锗的器件的整体集成
公开(公告)号：US09146349B2
公开(公告)日：2015-09-29
申请号：US13077086
申请日：2011-03-31
申请人： Long Chen , Christopher Doerr , Young-Kai Chen
发明人： Long Chen , Christopher Doerr , Young-Kai Chen
IPC分类号： G02B6/12 , G02B6/122 , G02B6/42 , G02B6/43
CPC分类号： G02B6/12004 , G02B6/122 , G02B6/42 , G02B6/43 , G02B2006/12061 , G02B2006/1208
摘要： Various exemplary embodiments relate to an integrated optical device including: a semiconductor waveguide on a substrate; a dielectric waveguide on a substrate optically coupled to the semiconductor waveguide; and a germanium device on the semiconductor waveguide optically coupled to the semiconductor waveguide.
摘要翻译：各种示例性实施例涉及一种集成光学装置，包括：衬底上的半导体波导; 光电耦合到半导体波导的基板上的电介质波导; 以及光学耦合到半导体波导的半导体波导上的锗器件。

50. 发明授权

US08836224B2 Compact converter plug for LED light strings 有权
标题翻译：用于LED灯串的紧凑型转换插头
公开(公告)号：US08836224B2
公开(公告)日：2014-09-16
申请号：US12834949
申请日：2010-07-13
申请人： Long Chen , Beijing Yu , Jing Jing Yu
发明人： Long Chen , Beijing Yu , Jing Jing Yu
IPC分类号： H05B37/02 , H05B33/08 , H02M7/00 , H01R13/66
CPC分类号： H05B33/0815 , H01R13/665 , H02M7/003 , Y02B20/19
摘要： Disclosed is a compact inverter plug that can be used with LED lighting strings. The converter plug has a size and shape that is comparable to a standard wall plug and is capable of plugging into a standard wall socket. The converter plug is waterproof and can be easily assembled. A unique converter circuit is utilized that is compact and highly efficient. Monitoring is performed by a transformer coil that generates a monitoring signal. The converter is controlled by controlling the modulation frequency of a direct current signal using a controller.
摘要翻译：公开了可与LED照明灯串一起使用的紧凑型逆变器插头。转换器插头的尺寸和形状与标准墙壁插头相当，并且能够插入标准墙壁插座。转换器插头是防水的，可以方便地组装。使用独特的转换器电路，其紧凑且高效。监控由产生监控信号的变压器线圈执行。通过使用控制器控制直流信号的调制频率来控制转换器。

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