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41. 发明申请

US20100266724A1 METHOD FOR PRODUCING AN ACIDIFIED MILK DRINK 审中-公开
标题翻译：生产酸奶饮料的方法
公开(公告)号：US20100266724A1
公开(公告)日：2010-10-21
申请号：US12678384
申请日：2008-09-16
申请人： Jeppe Wegener Tams , Preben Nielsen , Kirk Matthew Schnorr
发明人： Jeppe Wegener Tams , Preben Nielsen , Kirk Matthew Schnorr
IPC分类号： A23C9/12
CPC分类号： A23C9/1213 , A23C9/1275 , C12N9/0059 , C12Y110/03001 , C12Y110/03002 , C12Y114/18001
摘要： The present invention relates to a method for producing an acidified milk drink using an enzyme having phenoloxidase activity.
摘要翻译：本发明涉及使用具有酚氧化酶活性的酶来生产酸化乳饮料的方法。

42. 发明申请

US20100151111A1 Polypeptides of Strain Bacillus SP. P203 失效
标题翻译：菌株芽孢杆菌多肽 P203
公开(公告)号：US20100151111A1
公开(公告)日：2010-06-17
申请号：US12063599
申请日：2006-08-15
申请人： Preben Nielsen , Reinhard Wilting , Martin Borchert
发明人： Preben Nielsen , Reinhard Wilting , Martin Borchert
IPC分类号： C11D7/42 , C07K2/00 , C07K14/00 , C12N9/42 , C12N9/50 , C12N9/88 , C12N9/24 , C12N9/00 , C07H21/02 , C12N15/74 , C12N1/21 , C12P21/02 , C07H21/04 , A23L1/10
CPC分类号： C12N9/54 , C12N9/2468 , C12N9/248 , C12N9/88 , C12Y302/01008 , C12Y305/02006 , C12Y402/01001
摘要： A new strain Bacillus sp. P203 (Bacillus plakortiensis) is disclosed. Isolated mature functional polypeptide which is obtainable from the bacterium strain Bacillus sp. P203 deposited under accession number DSM 17419 are disclosed.
摘要翻译：新菌株芽孢杆菌公开了P203（Bacillus plakortiensis）。分离的成熟功能性多肽，其可从细菌菌株芽孢杆菌属公开了以登录号DSM17419保藏的P203。

43. 发明申请

US20100151081A1 Method For Producing An Acidified Milk Drink 审中-公开
标题翻译：生产酸化牛奶饮料的方法
公开(公告)号：US20100151081A1
公开(公告)日：2010-06-17
申请号：US12597014
申请日：2008-05-10
申请人： Jeppe Wegener Tams , Preben Nielsen
发明人： Jeppe Wegener Tams , Preben Nielsen
IPC分类号： A23C9/12 , A23C9/127 , C12N9/48
CPC分类号： A23C9/1209 , A23C9/1216 , A23C9/1275 , A23Y2220/00 , C12N9/485 , C12N9/80 , C12Y304/16005 , C12Y305/01
摘要： The present invention relates to a method for producing an acidified milk drink using an enzyme which reduces the isoelectric point of the milk proteins. The invention also relates to a novel enzyme having deamidase activity and its use in production of an acidified milk drink.
摘要翻译：本发明涉及使用降低乳蛋白质等电点的酶来生产酸化乳饮料的方法。本发明还涉及具有脱酰胺酶活性的新型酶及其在酸化乳饮料生产中的应用。

44. 发明申请

US20060243804A1 Container comprising code information elements 审中-公开
标题翻译：容器包含代码信息元素
公开(公告)号：US20060243804A1
公开(公告)日：2006-11-02
申请号：US11396889
申请日：2006-04-03
申请人： Lasse Christoffersen , Preben Nielsen , Lennart Berggren
发明人： Lasse Christoffersen , Preben Nielsen , Lennart Berggren
IPC分类号： G06K7/10 , G06K19/00
CPC分类号： G06K7/14 , A61M5/14546 , A61M2205/3306 , A61M2205/6072 , C03C23/0025 , G16H20/10
摘要： This invention relates to a container (10) for a medication delivery (110) device comprising an optical reader (111), where said container comprises a code information element (20) carrying a set of information readable by said optical reader where the container comprises at least one more code information element (20) carrying the set of information readable by said optical reader. The invention further relates to a method of applying code information elements onto the container and to a method of reading a code information element. The code information elements can be aligned with at least one protrusion on the container, or are aligned with at least one cavity on the container. Alternatively or additionally, the code information elements are juxtaposed to one another. Hereby, an optical code reader, embedded in the medication delivery device, will be able securely to read the information carried by means of image processing software compiling and combining more code information elements. With more code information elements available, it is possible to re-create a perfect image from several code information elements applied on the container. Thus, the undesirable effects, arising from humidity, dirt, dirty or sweaty fingers damaging the code information elements are minimised.
摘要翻译：本发明涉及一种用于药物输送（110）装置的容器（10），其包括光学阅读器（111），其中所述容器包括承载由所述光学读取器可读的一组信息的代码信息元件（20），其中容器包括至少一个代码信息元素（20），承载由所述光学读取器读取的信息集合。本发明还涉及将代码信息元素应用到容器上的方法以及读取代码信息元素的方法。代码信息元素可以与容器上的至少一个突起对准，或者与容器上的至少一个空腔对准。或者或另外，代码信息元素彼此并置。因此，嵌入在药物传送装置中的光学代码读取器将能够安全地读取通过图像处理软件进行编码并组合更多代码信息元素的信息。随着更多的代码信息元素可用，可以从应用于容器上的多个代码信息元素重新创建完美的图像。因此，由于湿度，污垢，脏的或湿汗的手指导致代码信息元件的不良影响被最小化。

45. 发明申请

US20050095669A1 Eubacterial rna-polymerase mutants with altered product production 审中-公开
标题翻译：具有改变产品生产的真菌rna聚合酶突变体
公开(公告)号：US20050095669A1
公开(公告)日：2005-05-05
申请号：US10498302
申请日：2002-12-20
申请人： Steen Joergensen , Jens Toenne , Niels Banke , Preben Nielsen
发明人： Steen Joergensen , Jens Toenne , Niels Banke , Preben Nielsen
IPC分类号： C12N15/01 , C12N1/20 , C12N1/21 , C12N9/10 , C12N9/12 , C12P21/02 , C12N15/74
CPC分类号： C12N9/1247 , C12N9/2408 , C12N9/2417 , C12N9/54
摘要： The present invention relates to an isolated mutant eubacterium comprising at least one mutation resulting in a substitution of at least one amino acid in the beta-subunit of the RNA-polymerase encoded for by the rpoB-gene providing an altered production of a product of interest when said production of a product of interest is compared to the production of the same product in an isogenic wild type strain grown at identical conditions, wherein the substitution of at least one amino acid occurs at any of the positions 469, 478, 482, 485, or 487 of SEQ ID NO:2, or at the equivalent positions in any eubacterial RNA-polymererase beta-sub-unit family member. Another aspect of the invention relates to a process for producing at least one product of interest in a mutant eubacterium and to a use of the mutant eubacterium according to the invention for producing at least one product of interest.
摘要翻译：本发明涉及分离的突变体真细胞，其包含至少一个导致由rpoB基因编码的RNA聚合酶的β-亚基中的至少一个氨基酸取代的突变体，提供改变产生感兴趣的产物当所述感兴趣的产物的生产与在相同条件下生长的等基因野生型菌株中相同产物的产生进行比较时，其中至少一个氨基酸的取代发生在任何位置469,478,482,485 ，或SEQ ID NO：2的487，或在任何细菌RNA-多聚赖氨酸酶β-亚单位家族成员中的等同位置。本发明的另一方面涉及用于产生至少一种在突变体杆菌中感兴趣的产物的方法和本发明的突变型杆菌的用途，用于生产至少一种目标产物。

46. 发明授权

US09314573B2 Injection device with means for signalling the time since the last injection 有权
标题翻译：注射装置，具有用于发出自上次注射以来的时间的装置
公开(公告)号：US09314573B2
公开(公告)日：2016-04-19
申请号：US11665484
申请日：2005-10-20
申请人： Preben Nielsen , Christian Peter Enggaard , Thomas D. Miller , Bodo von Münchow , Klaus Thogersen
发明人： Preben Nielsen , Christian Peter Enggaard , Thomas D. Miller , Bodo von Münchow , Klaus Thogersen
IPC分类号： A61M5/24 , A61M5/315 , A61M5/31
CPC分类号： A61M5/24 , A61M5/31525 , A61M5/3155 , A61M2005/3126 , A61M2205/50 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/587 , A61M2205/8212
摘要： The present Invention relates to an injection device capable of emitting a flashing light signal indicating the time elapsed since last ejection and/or the size of the last ejected dosage and/or a return signal indicating the operable state of the device and/or a time out signal indicating when the pen can be removed after ejecting of a dosage. The injection device comprises an electronic control circuit comprising: a sensor unit arranged to detect the occurrence of an ejection of a drug from the injection device; a timer for determining an approximate time elapsed since last ejection; a signal emitting device being able to emit a signal, the signal emitting device being controllable by the electric control circuit, so as to emit a time signal that varies with the time elapsed since last ejection.
摘要翻译：本发明涉及能够发出指示自上次喷射以来经过的时间的闪光信号和/或最后喷射剂量的尺寸和/或指示装置的可操作状态的返回信号和/或时间指示在喷射剂量之后何时可以取出笔的信号。注射装置包括电子控制电路，其包括：传感器单元，被布置成检测药物从注射装置喷射的发生; 用于确定自上次喷射以来经过的大致时间的计时器; 信号发射装置能够发射信号，信号发射装置可由电气控制电路控制，以便发射随上次喷射所经过的时间而变化的时间信号。

47. 发明授权

US08221356B2 Medication delivery system with a detector for providing a signal indicative of an amount of a set and/or ejected dose of drug 有权
标题翻译：具有检测器的药物递送系统，用于提供指示药物的设定和/或喷射剂量的量的信号
公开(公告)号：US08221356B2
公开(公告)日：2012-07-17
申请号：US11665572
申请日：2005-10-20
申请人： Christian Peter Enggaard , Preben Nielsen , Bodo von Munchow
发明人： Christian Peter Enggaard , Preben Nielsen , Bodo von Munchow
IPC分类号： A61M1/00 , A61M5/00 , A61B18/18
CPC分类号： G01F11/023 , A61M5/20 , A61M5/24 , A61M5/315 , A61M5/31505 , A61M5/31525 , A61M5/31553 , A61M2005/3125 , A61M2005/3126 , A61M2205/3317 , A61M2205/3389 , A61M2205/3546 , A61M2205/50 , A61M2205/502 , A61M2205/583 , A61M2205/6018 , A61M2205/8206 , G01D5/2451 , G01D21/00 , G01F11/029
摘要： A medication delivery system, comprising: a movable part (230, 232) adapted to move relative to a stationary part; at least two conductors (234, 236) which are arranged such that an electrical characteristic is defined by the mutual position of the movable and the stationary part and/or by movement of one of said parts relative to the other; and a detector for detecting a change of said electrical characteristic, wherein the parts are stationary relative to each other during dose setting and in that the parts are moved relative to each other during dose ejection, such that that detector provides a signal indicative of the actual amount of the ejected dose.
摘要翻译：一种药物输送系统，包括：适于相对于静止部分移动的可动部分（230,232）; 至少两个导体（234,236）被布置成使得电特性由可移动和静止部分的相互位置和/或通过所述部件之一相对于另一部分的移动来限定; 以及检测器，用于检测所述电特性的变化，其中所述部件在剂量设定期间相对于彼此是静止的，并且所述部件在剂量喷射期间相对于彼此移动，使得所述检测器提供指示实际的喷射剂量。

48. 发明申请

US20110181301A1 Absolute Position Determination of Movably Mounted Member in Medication Delivery Device 有权
标题翻译：药物输送装置中活动安装构件的绝对位置确定
公开(公告)号：US20110181301A1
公开(公告)日：2011-07-28
申请号：US12295430
申请日：2007-04-12
申请人： Preben Nielsen , Bodo von Münchow , Peter Grønning Sørensen
发明人： Preben Nielsen , Bodo von Münchow , Peter Grønning Sørensen
IPC分类号： G01R27/28
CPC分类号： A61M5/31525 , A61M5/31533 , A61M5/3155 , A61M5/31556 , A61M2205/3317 , G01D5/1655
摘要： The present invention relates to a medication delivery device for expelling set doses of medicament, the medication delivery device comprising a position determining arrangement for detecting absolute positions of a movably mounted member, such as a dose indicator barrel, relative to a housing of the medication delivery device. The position determining arrangement comprises a plurality of electrically conducting electrodes arranged on an outer surface of the movably mounted member, and a plurality of contacts members fixedly arranged relative to the housing of the medication delivery device. A first and a second contact member are arranged to follow a first path across the electrically conducting electrodes upon movement of the movably mounted member relative to the housing, whereas a third and a fourth contact member are arranged to follow a second path across the electrically conducting electrodes upon movement of the movably mounted member relative to the housing.
摘要翻译：本发明涉及用于排出设定剂量的药物的药物输送装置，所述药物输送装置包括位置确定装置，用于相对于药物输送的壳体检测诸如剂量指示器筒的可移动安装构件的绝对位置设备。位置确定装置包括布置在可移动安装构件的外表面上的多个导电电极和相对于药物输送装置的壳体固定布置的多个触点构件。第一和第二接触构件布置成在可移动安装的构件相对于壳体移动时跟随穿过导电电极的第一路径，而第三和第四接触构件布置成沿着导电的第二路径可移动安装的构件相对于壳体移动时的电极。

49. 发明授权

US07067252B2 Method for genome mining for secreted protein genes 失效
公开(公告)号：US07067252B2
公开(公告)日：2006-06-27
申请号：US09882144
申请日：2001-06-15
申请人： Preben Nielsen , Birthe Ravn Jørgensen
发明人： Preben Nielsen , Birthe Ravn Jørgensen
IPC分类号： C12Q1/70 , C12Q1/68 , C12N15/00 , C12P21/06 , C07H21/04
CPC分类号： C12N15/1034
摘要： The present invention relates to a method for screening for compounds secreted by an organism, comprising (a) raising antibodies against secreted products of a donor organism, (b) providing a gene library from the donor organism, (c) cloning the gene library into a suitable host organism, (d) expressing the cloned genes in the host organism, and (e) detecting positive clones, which upon expression of the cloned genes secretes a compound, using the antibodies of (a) to identify such positive clones. The invention also relates to compounds, nucleotide sequences and microorganisms identifiable by said method.

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