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41. 发明授权

US08647702B2 Maintaining a fixed distance by providing an air cushion during coating of a medical device 有权
标题翻译：通过在医疗装置的涂覆期间提供气垫来保持固定的距离
公开(公告)号：US08647702B2
公开(公告)日：2014-02-11
申请号：US13158101
申请日：2011-06-10
申请人： Randy Shen , Michael J. Leonard , Anthony S. Andreacchi
发明人： Randy Shen , Michael J. Leonard , Anthony S. Andreacchi
IPC分类号： A61M25/00
CPC分类号： A61M25/1029 , A61M2025/1031 , A61M2025/105 , B05B13/0442 , B05C5/00 , B05D3/00
摘要： System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by ejecting a pressurized medium against the surface of the expandable member.
摘要翻译：用于涂覆医疗装置的可膨胀构件的系统和方法，包括支撑结构以支撑可膨胀构件，以及施加器，其定位成邻近可扩张构件的表面的至少一个出口。驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。定位装置通过相对于可膨胀构件的表面喷射加压介质而在相对运动期间在至少一个出口和可膨胀构件的表面之间保持基本上固定的距离。

42. 发明申请

US20120064141A1 Drug-Coated Balloon With Location-Specific Plasma Treatment 有权
标题翻译：具有位置特异性等离子体处理的药物涂层气球
公开(公告)号：US20120064141A1
公开(公告)日：2012-03-15
申请号：US12883024
申请日：2010-09-15
申请人： Anthony S. Andreacchi , Stephen D. Pacetti , John Stankus , Victoria M. Gong , Michael J. Leonard , Binh Nguyen
发明人： Anthony S. Andreacchi , Stephen D. Pacetti , John Stankus , Victoria M. Gong , Michael J. Leonard , Binh Nguyen
IPC分类号： A61F2/00 , B05D3/06 , C23C14/02
CPC分类号： B05D3/144 , A61F2/82 , B05D7/02 , C08J7/123
摘要： Method of coating an expandable member, e.g. balloon, is provided, the method comprising providing an expandable member having an outer surface. The method includes a plasma treatment with a supply of gas performed on at least a portion of the outer surface of the expandable member. A therapeutic agent is applied on at least the plasma treated portion of the outer surface of the expandable member after the plasma treatment is performed. The plasma treatment can reduce the adhesion of therapeutic agent to the surface of the expandable member. A medical device made by the disclosed method is also provided.
摘要翻译：涂覆可膨胀构件的方法，例如气囊，所述方法包括提供具有外表面的可扩张构件。该方法包括在可扩张构件的外表面的至少一部分上进行气体供应的等离子体处理。在执行等离子体处理之后，至少在可膨胀构件的外表面的等离子体处理部分上施加治疗剂。等离子体处理可以降低治疗剂对可扩张构件表面的粘附。还提供了通过所公开的方法制造的医疗装置。

43. 发明授权

US08815061B2 Electropolishing fixture with plunger mechanism 有权
标题翻译：带柱塞机构的电抛光夹具
公开(公告)号：US08815061B2
公开(公告)日：2014-08-26
申请号：US13618348
申请日：2012-09-14
申请人： Anthony S. Andreacchi , Sophia L. Wong
发明人： Anthony S. Andreacchi , Sophia L. Wong
IPC分类号： C25F3/16 , C25F7/00 , A61F2/82
CPC分类号： C25F3/16 , A61F2/82 , C25F7/00
摘要： An electropolishing fixture with a plunger mechanism. The plunger mechanism can establish contact between a device and an anode mandrel during an electropolishing process while the device is immersed in an electrolytic bath.
摘要翻译：具有柱塞机构的电抛光夹具。柱塞机构可以在电解抛光过程中在器件浸入电解槽中之间建立装置与阳极心轴之间的接触。

44. 发明申请

US20140076739A1 ELECTROPOLISHING DEVICE AND METHOD 有权
标题翻译：电镀装置和方法
公开(公告)号：US20140076739A1
公开(公告)日：2014-03-20
申请号：US13618407
申请日：2012-09-14
申请人： Anthony S. Andreacchi
发明人： Anthony S. Andreacchi
IPC分类号： C25F7/00 , C25F3/16
CPC分类号： C25F3/16 , A61F2/82 , A61F2/89 , A61F2/91 , C25F7/00
摘要： A device for repositioning a device during an electropolishing process. A fixture is disclosed that is configured to reposition the device during the electropolishing process in order to more evenly electropolish a surface of the device.
摘要翻译：在电抛光过程中重新定位器件的装置。公开了一种固定装置，其被配置为在电抛光过程期间重新定位该装置，以便更均匀地电镀设备的表面。

45. 发明申请

US20140076737A1 ELECTROPOLISHING FIXTURE WITH PLUNGER MECHANISM 有权
标题翻译：电镀机器与PLUNGER机制
公开(公告)号：US20140076737A1
公开(公告)日：2014-03-20
申请号：US13618348
申请日：2012-09-14
申请人： Anthony S. Andreacchi , Sophia L. Wong
发明人： Anthony S. Andreacchi , Sophia L. Wong
IPC分类号： C25F7/00 , C25F3/16
CPC分类号： C25F3/16 , A61F2/82 , C25F7/00
摘要： An electropolishing fixture with a plunger mechanism. The plunger mechanism can establish contact between a device and an anode mandrel during an electropolishing process while the device is immersed in an electrolytic bath.
摘要翻译：具有柱塞机构的电抛光夹具。柱塞机构可以在电解抛光过程中在器件浸入电解槽中之间建立装置与阳极心轴之间的接触。

46. 发明申请

US20130008780A1 AUTOMATED ELECTROPOLISHING PROCESS 审中-公开
公开(公告)号：US20130008780A1
公开(公告)日：2013-01-10
申请号：US13615540
申请日：2012-09-13
申请人： Anthony S. Andreacchi , Andreina P. Gomez , Han Juanta , Jessie Madriaga , Dan Joel Dirilo
发明人： Anthony S. Andreacchi , Andreina P. Gomez , Han Juanta , Jessie Madriaga , Dan Joel Dirilo
IPC分类号： C25F7/00 , C25F3/16 , B23H3/04
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/001 , C25F3/24
摘要： An electropolishing system including an anode, a cathode, a rolling block and a motion controller. The anode is configured to removably retain a metal device to be electropolished, and may be formed as a bar made from a solid cylindrical piece of metal or other configurations, such as wires with hooks. The anode transfers the electricity to the metal device while grooming the surface of the metal device as it contacts the rolling block. The cathode may be configured as a mesh and completes the electrical circuit. The rolling block is formed from a relatively smooth, solid material and positioned so as to allow the metal device to roll against the surface of the block. The motion controller is configured to provide vertical and horizontal movement of the anode and metal device, using force transducers to control the compression of the metal device against the rolling block.

47. 发明申请

US20120315375A1 Maintaining A Fixed Distance By Providing An Air Cushion During Coating Of A Medical Device 有权
标题翻译：通过在医疗器械涂层期间提供空气垫片来维持固定距离
公开(公告)号：US20120315375A1
公开(公告)日：2012-12-13
申请号：US13158101
申请日：2011-06-10
申请人： Randy Shen , Michael J. Leonard , Anthony S. Andreacchi
发明人： Randy Shen , Michael J. Leonard , Anthony S. Andreacchi
IPC分类号： A61M25/10 , B05C11/00
CPC分类号： A61M25/1029 , A61M2025/1031 , A61M2025/105 , B05B13/0442 , B05C5/00 , B05D3/00
摘要： System and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A positioning device maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by ejecting a pressurized medium against the surface of the expandable member.
摘要翻译：用于涂覆医疗装置的可膨胀构件的系统和方法，包括支撑结构以支撑可膨胀构件，以及施加器，其定位成邻近可扩张构件的表面的至少一个出口。驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。定位装置通过相对于可膨胀构件的表面喷射加压介质而在相对运动期间在至少一个出口和可膨胀构件的表面之间保持基本上固定的距离。

48. 发明授权

US08323459B2 Automated electropolishing process 有权
标题翻译：自动电解抛光工艺
公开(公告)号：US08323459B2
公开(公告)日：2012-12-04
申请号：US12100991
申请日：2008-04-10
申请人： Anthony S. Andreacchi , Andreina P. Gomez , Han Juanta , Jessie Madriaga , Dan Joel Dirilo
发明人： Anthony S. Andreacchi , Andreina P. Gomez , Han Juanta , Jessie Madriaga , Dan Joel Dirilo
IPC分类号： C25D17/00 , B23H3/00 , B23H7/00 , B23H3/04
CPC分类号： C25F7/00 , A61F2/91 , A61F2240/001 , C25F3/24
摘要： An electropolishing system including an anode, a cathode, a rolling block and a motion controller. The anode is configured to removably retain a metal device to be electropolished, and may be formed as a bar made from a solid cylindrical piece of metal or other configurations, such as wires with hooks. The anode transfers the electricity to the metal device while grooming the surface of the metal device as it contacts the rolling block. The cathode may be configured as a mesh and completes the electrical circuit. The rolling block is formed from a relatively smooth, solid material and positioned so as to allow the metal device to roll against the surface of the block. The motion controller is configured to provide vertical and horizontal movement of the anode and metal device, using force transducers to control the compression of the metal device against the rolling block.
摘要翻译：一种电抛光系统，包括阳极，阴极，滚动块和运动控制器。阳极构造成可移除地保持待电抛光的金属装置，并且可以形成为由实心圆柱形金属片或其它构造制成的条，例如具有钩的线。当金属装置接触轧制块时，阳极将金属装置的电力转移到金属装置。阴极可以被配置为网状物并且完成电路。滚动块由相对光滑的固体材料形成并且被定位成允许金属装置滚动抵靠块的表面。运动控制器被配置为使用力传感器来提供阳极和金属装置的垂直和水平移动，以控制金属装置抵抗轧制块的压缩。

49. 发明申请

US20110281020A1 Maintaining A Fixed Distance During Coating Of Drug Coated Balloon 有权
标题翻译：在药物涂层气球涂层期间保持固定距离
公开(公告)号：US20110281020A1
公开(公告)日：2011-11-17
申请号：US13109156
申请日：2011-05-17
申请人： Victoria M. Gong , Stephen D. Pacetti , Anthony S. Andreacchi , Michael Leonard , Binh T. Nguyen , John Stankus , Dan Cox
发明人： Victoria M. Gong , Stephen D. Pacetti , Anthony S. Andreacchi , Michael Leonard , Binh T. Nguyen , John Stankus , Dan Cox
IPC分类号： B05D1/26 , B05C11/00 , B05C5/02
CPC分类号： B05B15/001 , A61F2/958 , A61M25/1029 , A61M2025/1031 , B05B3/00 , B05B13/0235 , B05B15/16 , B05C5/022 , B05D1/002 , B05D1/26 , B05D3/0254
摘要： A system and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and a dispenser positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A guide maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the expandable member relative to the at least one outlet.
摘要翻译：一种用于涂覆医疗装置的可膨胀构件的系统和方法，包括支撑结构以支撑可膨胀构件，以及分配器，其定位成邻近可扩张构件的表面的至少一个出口。驱动组件在至少一个出口和可膨胀构件的表面之间建立相对运动，以沿着涂覆路径向可扩张构件的表面施加流体。引导件通过相对于至少一个出口移动可膨胀元件而在其间的相对运动期间在至少一个出口和可膨胀元件的表面之间保持基本上固定的距离。

50. 发明申请

US20090317537A1 Method and System for Selective Coating of Endoluminal Prostheses 有权
标题翻译：腔内假体选择性涂层方法与系统
公开(公告)号：US20090317537A1
公开(公告)日：2009-12-24
申请号：US12145141
申请日：2008-06-24
申请人： Anthony S. Andreacchi
发明人： Anthony S. Andreacchi
IPC分类号： B05D1/28 , B05C1/00
CPC分类号： B05C13/025 , A61L2420/02 , B05B13/0442 , B05B13/0618 , B05B13/0654 , B05C1/02 , B05C1/022 , B05C1/08 , B05C3/18 , B05C7/06 , B05C13/02 , B05D1/002 , B05D1/18 , B05D1/26
摘要： A system and method for coating an endoprosthesis involves an applicator capable of delivering a coating substance to the endoprosthesis without spraying. The applicator may have a tube or die through which a coating substance is moved upwards by capillary action or by means of a pump so as to form an accumulation of the coating substance at an upper portion of the applicator. The endoprosthesis can be lowered onto the accumulation, then axially translated or rotated in order to transfer the coating substance to selected portions of the endoprosthesis. The applicator is lowered and/or the endoprosthesis is raised in order to form gaps in the coating. Selective coating of abluminal or luminal surface of the endoprosthesis may also be performed by allowing the surface to skip on a liquid surface of a pool of the coating substance.
摘要翻译：用于涂覆内假体的系统和方法涉及能够在不喷涂的情况下将涂层物质递送到内用假体的施加器。施用器可以具有管或模具，通过该管或模具，涂层物质通过毛细管作用或通过泵向上移动，以在涂抹器的上部形成涂层物质的积聚。可以将内假体降低到积聚物上，然后轴向平移或旋转，以将涂层物质转移到内置假体的选定部分。降低施用器和/或升高内置假体以在涂层中形成间隙。可以通过允许表面跳过涂覆物质池的液体表面来进行内置假体的腔内或腔表面的选择性涂层。

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