会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 43. 发明申请
    • Novel uracil derivatives and medicinal use thereof
    • 新型尿嘧啶衍生物及其药用
    • US20060094737A1
    • 2006-05-04
    • US10528373
    • 2003-09-17
    • Yoshiaki IsobeMasanori TobeYoshifumi InoueMasakazu Isobe
    • Yoshiaki IsobeMasanori TobeYoshifumi InoueMasakazu Isobe
    • A61K31/513C07D405/02C07D239/54
    • C07D239/545A61K31/513C07D405/06C07D405/12C07D405/14
    • It is intended to provide an uracil derivative represented by the following general formula (I): (I) wherein X represents a group selected from among NHCO, NHCH2, CO, CONH and CH2NH; R1 represents hydrogen or optionally substituted C1-6 alkyl; R2 represents a group of the following general formula (II) or (III): (II) (III) (wherein m is 0 or 1; n is an integer of from 1 to 3; Y represents OH or NH2; and a dotted line shows a binding position), provided that when R2 is a group of the general formula (III), X represents NHCO or NHCH2; R3 and R4 independently represent each hydrogen or C1-6 alkyl; and Ar represents phenyl substituted by C1-6 alkyl at the o- and m-positions, optionally substituted heteroaryl or a bicyclic aromatic group; its pharmaceutically acceptable salt, and a remedy containing the above uracil derivative or its pharmaceutically acceptable salt as the active ingredient for, in particular, allergic diseases relating to a type IV allergic reaction, i.e., a novel compound useful in treating diseases in which a type IV allergic reaction participates and a remedy for allergic diseases containing the same as the active ingredient.
    • 旨在提供由以下通式(I)表示的尿嘧啶衍生物:(I)其中X表示选自NHCO,NHCH 2,CO,CONH和CH 2的基团 NH; R 1表示氢或任选取代的C 1-6烷基; R 2表示下述通式(II)或(III)的基团:(II)(III)(其中m为0或1; n为1至3的整数; Y 表示OH或NH 2,虚线表示结合位置),条件是当R 2为通式(III)的基团时,X表示NHCO或 NHCH 2
    • 44. 发明申请
    • Organosilicon compound
    • 有机硅化合物
    • US20050101791A1
    • 2005-05-12
    • US11015024
    • 2004-12-20
    • Toshiyuki OzaiHiroyasu HaraYoshifumi InoueTomoyuki Goto
    • Toshiyuki OzaiHiroyasu HaraYoshifumi InoueTomoyuki Goto
    • C07F7/08C07F7/18
    • C07F7/1804
    • An organosilicon compound represented by the following general formula (1): wherein R1 is a hydrogen atom, a phenyl group or a halogenated phenyl group; R2 is a hydrogen atom or a methyl group; R3's are each a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms; X is a hydrolyzable group; Z1 is —R4—, —R4O— or —R4(CH3)2SiO—, where R4 is a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; Z2 is an oxygen atom or a substituted or unsubstituted divalent hydrocarbon group having 1 to 10 carbon atoms; and m is 0, 1 or 2 and n is 0, 1 or 2. When incorporated in silicone compositions, the organosilicon compound acts as a cross-linking agent having well-balanced photopolymerizability and condensation curability.
    • 由以下通式(1)表示的有机硅化合物:其中R 1是氢原子,苯基或卤代苯基; R 2是氢原子或甲基; R 3各自为取代或未取代的碳原子数为1〜10的一价烃基; X是可水解基团; Z 1是-R 4 - , - R 4 O-或-R 4(CH 3) 3 SiO 2,其中R 4是取代或未取代的具有1至10个碳原子的二价烃基; Z 2是氧原子或取代或未取代的碳原子数为1〜10的二价烃基; 并且m为0,1或2,n为0,1或2.当掺入有机硅组合物中时,有机硅化合物用作具有良好平衡光聚合性和缩合固化性的交联剂。
    • 45. 发明授权
    • Room temperature curable silicone rubber composition
    • 室温可固化硅橡胶组合物
    • US06756425B2
    • 2004-06-29
    • US10291692
    • 2002-11-12
    • Hiroshi MogiYoshifumi Inoue
    • Hiroshi MogiYoshifumi Inoue
    • C08K906
    • C08K9/06C08G77/12C08G77/14C08G77/16C08G77/20C08G77/70C08L83/04C08L83/00
    • A condensation curable silicone rubber composition is provided which is able to suppress increases in viscosity over time, has an adequate pot life and excellent mold releasability, and displays favorable urethane molding durability. The composition includes: (A) an organopolysiloxane represented by a general formula (I), wherein, each R1 represents, independently, a substituted or unsubstituted monovalent hydrocarbon group, and n represents a number which results in a viscosity at 25° C. of 100 to 500,000 mm2/s, with a viscosity at 25° C. of 100 to 500,000 mm2/s; (B) a surface-treated reinforcing fine silica powder with a specific surface area as measured by a BET method of at least 50 m2/g, and a tap density of 0.2 to 0.4 g/ml, which has undergone treatment with an organosilicon compound to produce a quantity of surface carbon of at least 2.5% by weight; and (C) a tin compound-based curing catalyst.
    • 提供了一种缩合可固化的硅橡胶组合物,其能够抑制随时间的粘度增加,具有足够的使用期和优异的脱模性,并且显示有利的聚氨酯模塑耐久性。 该组合物包括:(A)由通式(I)表示的有机聚硅氧烷,其中各R 1独立地表示取代或未取代的单价烃基,n表示25℃时的粘度 100至500,000mm 2 / s,粘度在25℃下为100至500,000mm 2 / s; (B)通过BET法测定的比表面积为至少50m 2 / g,振实密度为0.2〜0.4g / ml的经表面处理的增强微细二氧化硅粉末,其经历了 有机硅化合物,以产生至少2.5重量%的表面碳量; 和(C)锡化合物类固化催化剂。
    • 48. 发明授权
    • 2-trimethoxysilylpropionate
    • 2-三甲氧基甲硅烷基丙酸酯
    • US5286892A
    • 1994-02-15
    • US985868
    • 1992-12-04
    • Masatoshi AraiTakafumi SakamotoYoshifumi InoueKei Miyoshi
    • Masatoshi AraiTakafumi SakamotoYoshifumi InoueKei Miyoshi
    • C07F7/04C07F7/18C09K3/00C07F7/08
    • C07F7/045C07F7/1836
    • The present novel organosilicon compound is a 2-trimethoxysilylpropionate represented by the following formula ##STR1## wherein R represents a monovalent hydrocarbon group having 6 to 12 carbon atoms. This ester reacts efficiently with alcohols and silanols and is useful, for example, as a terminal alkoxysilylating agent for organopolysiloxanes such as industrially useful .alpha.,.omega.-dihydroxypolydimethylsiloxane, or as a surface treatment for silicas, or as a storage stabilizer that serves as a scavenger of an alcohol for alcohol elimination type RTV. Further, since the present organosilicon compound is a three-functional alkoxysilane having three methoxy groups in the molecule, it is useful as a curing agent for alcohol elimination type RTV.
    • 本发明的新型有机硅化合物是由下式(*化学结构*)表示的2-三甲氧基甲硅烷基丙酸酯,其中R表示碳原子数为6〜12的一价烃基。 该酯与醇和硅烷醇有效反应,并且可用作例如工业上有用的(α),(ω) - 二羟基聚二甲基硅氧烷的有机聚硅氧烷的末端烷氧基硅烷化剂,或作为二氧化硅的表面处理或作为储存稳定剂 作为酒精消除型RTV的酒精清除剂。 此外,由于本发明的有机硅化合物是分子中具有三个甲氧基的三官能烷氧基硅烷,因此可用作醇消除型RTV的固化剂。