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1. 发明授权

US6150377A Alkynyl-substituted quinolin-2-one derivatives useful as anticancer agents 有权
标题翻译：用作抗癌剂的炔基取代的喹啉-2-酮衍生物
公开(公告)号：US6150377A
公开(公告)日：2000-11-21
申请号：US383755
申请日：1999-08-26
申请人： Joseph P. Lyssikatos , Susan D. La Greca
发明人： Joseph P. Lyssikatos , Susan D. La Greca
IPC分类号： C07D401/06 , A61K31/47 , A61K31/4709 , A61P9/00 , A61P13/00 , A61P17/06 , A61P35/00 , A61P43/00 , C07D215/22 , C07D401/10 , C07D401/14 , C07F7/08 , C07F7/18 , C07D215/16 , C07D215/20 , C07D215/36
CPC分类号： C07D401/10 , C07D401/14 , C07F7/1836
摘要： The present invention relates to compounds of formula 1 and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, R.sup.9, R.sup.10, and R.sup.11 are as defined herein. The above compounds of formula 1 are useful in the treatment of hyperproliferative disorders, such as cancer, in mammals. The invention also relates to pharmaceutical compositions containing the compounds of formula 1 and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering the compounds of formula 1 to a mammal requiring such treatment.
摘要翻译：本发明涉及式1化合物及其药学上可接受的盐，前药和溶剂化物，其中R1，R2，R3，R4，R5，R6，R7，R8，R9，R10和R11如本文所定义。上述式1化合物可用于治疗哺乳动物中的过度增殖性疾病如癌症。本发明还涉及含有式1化合物的药物组合物以及通过向需要这种治疗的哺乳动物施用式1化合物来抑制哺乳动物异常细胞生长（包括癌症）的方法。

2. 发明授权

US06140523A Organosilicon compounds and making method 有权
标题翻译：有机硅化合物及其制备方法
公开(公告)号：US06140523A
公开(公告)日：2000-10-31
申请号：US472895
申请日：1999-12-28
申请人： Hideyoshi Yanagisawa , Masaaki Yamaya
发明人： Hideyoshi Yanagisawa , Masaaki Yamaya
IPC分类号： C07F7/18 , G07F7/10
CPC分类号： C07F7/1836 , C07F7/184
摘要： Novel organosilicon compounds containing organooxysilyl and sulfenamide groups in the molecule are provided. They are useful as interfacial binders between inorganic materials and organic materials, adhesion modifiers for organic resins and rubber, primers, etc.
摘要翻译：提供了分子中含有有机氧基甲硅烷基和次磺酰胺基团的新型有机硅化合物。它们可用作无机材料和有机材料之间的界面粘合剂，有机树脂和橡胶的粘合改性剂，底漆等。

3. 发明授权

US6113815A Ether-stabilized organosilane compositions and methods for using the same 失效
标题翻译：醚稳定的有机硅烷组合物及其使用方法
公开(公告)号：US6113815A
公开(公告)日：2000-09-05
申请号：US116636
申请日：1998-07-16
申请人： Jacques E. Elfersy , Joachim Berkner , Timothy C. Moses
发明人： Jacques E. Elfersy , Joachim Berkner , Timothy C. Moses
IPC分类号： A01N25/26 , A01N55/00 , A01N55/10 , A61L2/18 , C07F7/18 , C09D4/00 , C09D183/04 , C09D183/08 , D06M13/165 , D06M13/513 , D06M16/00 , D06P1/44 , D06P1/64 , D06P1/651 , A01N3/02 , A01N25/24 , A61K31/695 , C08G77/04 , C07F7/14
CPC分类号： D06P1/65131 , A01N55/00 , A61L2/18 , C07F7/1836 , C09D183/08 , C09D4/00 , D06M13/165 , D06M13/513 , D06M16/00 , D06P1/64
摘要： The composition formed by mixing an organosilane with an ether. Water-stabilized organosilane compounds. A water stable composition made from the ether and organosilane composition and water. A method of treating a substrate by mixing or contacting the substrate with the product, compound, or composition of this invention for a period of time sufficient for treatment of the substrate. A treated substrate having adhered thereto the product, compound, or composition of this invention. A method of dyeing and treating a substrate. A method of antimicrobially treating a food article. A method of antimicrobially coating a fluid container. A method of antimicrobially coating a latex medical article.
摘要翻译：通过将有机硅烷与醚混合而形成的组合物。水稳定的有机硅烷化合物。由醚和有机硅烷组合物和水制成的水稳定组合物。通过将底物与本发明的产品，化合物或组合物混合或接触足以处理底物的时间段来处理底物的方法。已经粘附了本发明的产品，化合物或组合物的经处理的基材。染色和处理底物的方法。一种抗微生物处理食品的方法。一种抗微生物涂覆流体容器的方法。一种抗微生物涂布乳胶医疗制品的方法。

4. 发明授权

US5965761A Photoactive silane derivatives for liquid crystals 失效
标题翻译：用于液晶的光活性硅烷衍生物
公开(公告)号：US5965761A
公开(公告)日：1999-10-12
申请号：US957096
申请日：1997-10-24
申请人： Richard Buchecker , Fran.cedilla.ois Herzog , Guy Marck , Andreas Schuster
发明人： Richard Buchecker , Fran.cedilla.ois Herzog , Guy Marck , Andreas Schuster
IPC分类号： C09K19/56 , C07F7/12 , C07F7/18 , C09K19/40 , G02F1/1337 , C07F7/08 , C07F7/10
CPC分类号： C09K19/406 , C07F7/12 , C07F7/1836 , G02F1/133719
摘要： The invention provides novel cross-linkable, photoactive silane derivatives and mixtures with 3-aryl-acrylic acid esters and amides. The present invention also provides orienting layers for liquid crystals, and non-structured and structured optical elements and multi-layer systems based on the silane mixtures and derivatives.
摘要翻译：本发明提供新的可交联的光活性硅烷衍生物和与3-芳基 - 丙烯酸酯和酰胺的混合物。本发明还提供了用于液晶的取向层，以及基于硅烷混合物和衍生物的非结构化和结构化的光学元件和多层系统。

5. 发明授权

US5959014A Water-stabilized organosilane compounds and methods for using the same 失效
标题翻译：水稳定性有机硅烷化合物及其使用方法
公开(公告)号：US5959014A
公开(公告)日：1999-09-28
申请号：US646156
申请日：1996-05-07
申请人： Lanny S. Liebeskind , Gary D. Allred
发明人： Lanny S. Liebeskind , Gary D. Allred
IPC分类号： C07F7/18 , C09D4/00 , C08K3/20
CPC分类号： C09D4/00 , C07F7/1836
摘要： The product of reacting an organosilane optionally having a nonhydrolizable organic group, but having one or more hydrolyzable groups, with a polyol containing at least three hydroxy groups, where any two of the hydroxy groups are separated by at least three intervening atoms. Water-stabilized organosilane compounds. A water stable composition made from the product or compound and water. A method of treating a substrate by contacting the substrate with the product, compound, or composition for a period of time sufficient for treatment of the substrate. A treated substrate having adhered thereto the product, compound, or composition.
摘要翻译：将任选具有不可水解的有机基团但具有一个或多个可水解基团的有机硅烷与含有至少三个羟基的多元醇反应的产物，其中任意两个羟基被至少三个中间原子隔开。水稳定的有机硅烷化合物。由产品或化合物和水制成的水稳定组合物。通过使底物与产物，化合物或组合物接触足以处理底物的时间段来处理底物的方法。经处理的基材，其上附着有产品，化合物或组合物。

6. 发明授权

US5948927A Bis-silyl tertiary amines 失效
标题翻译：双甲硅烷基叔胺
公开(公告)号：US5948927A
公开(公告)日：1999-09-07
申请号：US53292
申请日：1998-04-01
申请人： Michael Lee Gunther , Eric Raymond Pohl
发明人： Michael Lee Gunther , Eric Raymond Pohl
IPC分类号： C07F7/18 , C07F7/10
CPC分类号： C07F7/1836
摘要： Bis-silyl tertiary amines of the formula (I) �((R.sup.1).sub.b Y).sub.a R.sup.2.sub.3-a SiR.sup.3 !.sub.2 NX wherein R.sup.1 and R.sup.2 are monovalent radicals, R.sup.3 is a divalent radical, X is a monovalent carbonyl containing radical, Y is oxygen, nitrogen or sulfur, a=1 to 3, and b=1 or 2 depending upon the valency of Y, provide controlled reactivity, crosslinking and good adhesion
摘要翻译：式（I）[（（R1）bY）aR23-aSiR3] 2NX的双甲硅烷基叔胺其中R 1和R 2是一价基团，R 3是二价基团，X是含有一价羰基的基团，Y是氧，氮或硫，a = 1至3，b = 1或2，这取决于Y的化合价，提供受控的反应性，交联和良好的附着力

7. 发明授权

US5932667A Reactive adducts of vinyldioxo compounds 失效
标题翻译：乙烯基二氧化合物的活性加合物
公开(公告)号：US5932667A
公开(公告)日：1999-08-03
申请号：US670956
申请日：1996-06-26
申请人： Basil V. Gregorovich , Isidor Hazan , Hisanori Omura
发明人： Basil V. Gregorovich , Isidor Hazan , Hisanori Omura
IPC分类号： C07F7/04 , C07F7/18 , C08F283/00 , C08G77/06 , C07D319/06 , C07D305/00
CPC分类号： C07F7/1836 , C07F7/04 , C07F7/182
摘要： Adducts of vinyldioxo compounds comprising a crosslinkable silyl-functional terminal group are disclosed. Such adducts are useful for preparing curable coating compositions.
摘要翻译：公开了包含可交联甲硅烷基官能端基的乙烯基二氧代化合物的加合物。这种加合物可用于制备可固化涂料组合物。

8. 发明授权

US5912374A Asymmetrical siloxy compounds 失效
标题翻译：不对称甲硅烷基化合物
公开(公告)号：US5912374A
公开(公告)日：1999-06-15
申请号：US910781
申请日：1997-08-13
申请人： Giorgio Agostini , Thierry Florent Edme Materne , Marc Junio , Friedrich Visel , Uwe Ernst Frank
发明人： Giorgio Agostini , Thierry Florent Edme Materne , Marc Junio , Friedrich Visel , Uwe Ernst Frank
IPC分类号： B60C1/00 , C07F7/02 , C07F7/18 , C07F7/28 , C07F9/165 , C07F9/201 , C07F9/535 , C08K3/36 , C08K5/54 , C08K5/548 , C08K5/56 , C08L9/06 , C07F7/08 , C08L9/00
CPC分类号： C08K5/5406 , C07F7/1836 , C07F9/1655 , C07F9/201 , C08K5/548 , C08K5/56 , Y10S152/905
摘要： The present invention relates to asymmetrical siloxy compounds of the formulae ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are independently selected from the group consisting of alkoxy radicals having from 1 to 8 carbon atoms; R.sup.4 is selected from the group consisting of alkylene groups having from 1 to 15 carbon atoms and arylene and alkyl substituted arylene groups having from 6 to 10 carbon atoms; R.sup.5 is selected from the group consisting of alkylene groups having from 1 to 15 carbon atoms, arylene and alkyl substituted arylene groups having 6 to 10 carbon atoms; y is 2 to 8; X is selected from the group consisting of ##STR2## W is selected from the group consisting of ##STR3## and Z is 1 to 8
摘要翻译：本发明涉及下式的不对称甲硅烷氧基化合物，其中R 1，R 2和R 3独立地选自具有1至8个碳原子的烷氧基; R4选自具有1至15个碳原子的亚烷基和具有6至10个碳原子的亚芳基和烷基取代的亚芳基; R5选自具有1至15个碳原子的亚烷基，亚芳基和具有6至10个碳原子的烷基取代的亚芳基; y为2〜8; X选自W选自由Z组成的组，Z为1至8

9. 发明授权

US5767301A Precursor with (alkyloxy)(alkyl)-silylolefin ligand to deposit copper 失效
标题翻译：（烷氧基） - 硅烷基烯属配体的前体，以沉积铜
公开(公告)号：US5767301A
公开(公告)日：1998-06-16
申请号：US786546
申请日：1997-01-21
申请人： Yoshihide Senzaki , Masato Kobayashi , Lawrence J. Charneski , Tue Nguyen
发明人： Yoshihide Senzaki , Masato Kobayashi , Lawrence J. Charneski , Tue Nguyen
IPC分类号： C07F7/18 , C23C16/18 , H01L21/28 , H01L21/285 , C07F1/08
CPC分类号： C23C16/18 , C07F7/1836 , C07F7/184 , C07F7/1844
摘要： A method is provided for applying chemical vapor deposition (CVD) copper (Cu) to integrated circuit substrates using a Cu(hfac)(ligand) precursor with a silylolefin ligand including combinations of C1-C8 alkyl groups with at least one C2-C8 alkyloxy group. The alkyloxy groups include, ethoxy, propoxy, butoxy, pentyloxy, hexyloxy, heptyloxy, octyloxy, and aryloxy, while the alkyl groups include methyl, ethyl, propyl, butyl, pentyl, hexyl, heptyl, octyl, and aryl. The oxygen atoms of the alkyloxy groups, and the long carbon chains of both the alkyl and alkyloxy groups, increase the stability of the precursor by contributing electrons to the Cu(hfac) complex. The improved bond helps insure that the ligand separates from the (hfac)Cu complex at consistent temperatures when Cu is to be deposited. Combinations of alkyloxy and alkyl groups allow the molecular weight of the precursor to be manipulated so that the volatility of the precursor is adjustable for specific process scenarios. Other embodiments provide a precursor blend made from additional silylolefins, hexafluoroacetylacetone (H-hfac), H-hfac dihydrate, and water, either separately, or in combinations, to enhance deposition rate, conductivity, and precursor stability. A Cu precursor compound including silylolefin ligands having at least one alkyloxy group is also provided. Combinations of ethyl groups with ethoxy groups are specifically disclosed.
摘要翻译：提供了一种用于使用Cu（hfac）（配体）前体将金属化学气相沉积（CVD）铜（Cu）施加到集成电路衬底的方法，所述Cu（hfac）（配体）前体具有含有C 1 -C 8烷基与至少一个C 2 -C 8烷氧基组。烷氧基包括乙氧基，丙氧基，丁氧基，戊氧基，己氧基，庚氧基，辛氧基和芳氧基，而烷基包括甲基，乙基，丙基，丁基，戊基，己基，庚基，辛基和芳基。烷基氧基和烷基和烷氧基的长碳链的氧原子通过向Cu（hfac）络合物贡献电子而增加前体的稳定性。当Cu沉积时，改进的键有助于确保配体在恒定温度下与（hfac）Cu络合物分离。烷氧基和烷基的组合允许操纵前体的分子量，使得前体的挥发性对于具体的工艺情况是可调节的。其他实施方案提供由另外的水溶性烯烃，六氟乙酰丙酮（H-hfac），H-hfac二水合物和水分别或组合地制备的前体共混物，以增强沉积速率，导电性和前体稳定性。还提供了包含具有至少一个烷氧基的硅单元配体的Cu前体化合物。具体公开乙基与乙氧基的组合。

10. 发明授权

US5719251A Reactive organosilicon compounds 失效
标题翻译：活性有机硅化合物
公开(公告)号：US5719251A
公开(公告)日：1998-02-17
申请号：US703285
申请日：1996-08-26
申请人： Lech Wilczek , Idisor Hazan , Basil V. Gregorovich
发明人： Lech Wilczek , Idisor Hazan , Basil V. Gregorovich
IPC分类号： C07F7/12 , C07F7/18 , C09D7/12 , C09D183/14 , C09D201/00 , C08G77/04
CPC分类号： C09D183/14 , C07F7/12 , C07F7/1836
摘要： Organosilicon compounds are described which contain a cyclic organic moiety between at least two reactive silane groups. The compounds are useful in coatings, adhesives, and sealants, and the like.
摘要翻译：描述了在至少两个反应性硅烷基团之间含有环状有机部分的有机硅化合物。这些化合物可用于涂料，粘合剂和密封剂等。

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